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Science, ISSN 0036-8075, 6/2007, Volume 316, Issue 5829, pp. 1349 - 1353
Proteasomes are responsible for generating peptides presented by the class I major histocompatibility complex (MHC) molecules of the immune system. Here, we... 
T lymphocytes | Molecules | Thymocytes | Epithelial cells | Stromal cells | Positive selection | Stem cells | Amino acids | Ligands | Reports | Cellular immunity | 20S PROTEASOME | IMMUNOPROTEASOMES | TOLERANCE | MULTIDISCIPLINARY SCIENCES | ANTIGEN PRESENTATION | GENERATION | SELECTION | PROTEINS | MICE LACKING | T-Lymphocyte Subsets - immunology | CD8-Positive T-Lymphocytes - cytology | Lymphopoiesis | Autoantigens - metabolism | Spleen - immunology | T-Lymphocyte Subsets - cytology | Humans | Molecular Sequence Data | Green Fluorescent Proteins - genetics | Thymus Gland - enzymology | CD4-Positive T-Lymphocytes - immunology | Histocompatibility Antigens Class I - metabolism | Peptides - metabolism | Amino Acid Sequence | Green Fluorescent Proteins - metabolism | Catalytic Domain | Peptides - chemistry | CD4-Positive T-Lymphocytes - cytology | Histocompatibility Antigens Class I - immunology | Thymus Gland - cytology | Proteasome Endopeptidase Complex - chemistry | Spleen - cytology | Proteasome Endopeptidase Complex - genetics | Animals | Autoantigens - immunology | Epithelial Cells - enzymology | Thymus Gland - immunology | Proteasome Endopeptidase Complex - metabolism | CD8-Positive T-Lymphocytes - immunology | Biomedical research | Immunology | Cellular biology | Peptides | Endocrine system | Rodents | Catalysis
Journal Article
by Yamagami, Keitaro and Kurogi, Ryota and Kurogi, Ai and Nishimura, Hiroyuki and Nishimura, Shinjitsu and Nishimura, Yasuaki and Nishimura, Kunihiro and Nishimura, Ataru and Onozuka, Daisuke and Ren, Nice and Kada, Akiko and Arimura, Koichi and Ido, Keisuke and Mizoguchi, Masahiro and Sakamoto, Seisaburo and Sakamoto, Tetsuya and Kayama, Takamasa and Suzuki, Nozomi and Suzuki, Michiyasu and Suzuki, Sachio and Suzuki, Hidenori and Suzuki, Ichiro and Suzuki, Susumu and Arai, Yoshinori and Arai, Hajime and Arai, Motohiro and Hagihara, Akihito and Iihara, Koji and Takigami, Masayoshi and Kamiyama, Kenji and Houkin, Kiyohiro and Nishi, Shougo and Yoshimoto, Tetsuyuki and Yoshimoto, Junpei and Kaneko, Sadao and Oka, Hirofumi and Oka, Koji and Ooyama, Hiroshi and Kamada, Kyousuke and Makino, Kenichi and Tokumitsu, Naoki and Sako, Kazuhiro and Izumi, Naoto and Nitta, Hisashi and Nitta, Kazumi and Ootaki, Masahumi and Isobe, Masanori and Nishiya, Mikio and Yamazaki, Takaaki and Mabuchi, Syouji and Mabuchi, Eiichiro and Ogasawara, Kuniaki and Kubo, Naohiko and Shimizu, Yukihiko and Saito, Hitoshi and Saito, Keiichi and Yamanome, Tatumi and Yoshino, Kimihiro and Yoshino, Atsuo and Fujitsuka, Mitsuyuki and Takami, Masaaki and Ohtaka, Hirotoshi and Hirano, Teruyuki and Shiokawa, Yosiaki and Okada, Takaharu and Kohno, Michihiro and Haraoka, Jou and Kawamura, Noriyoshi and Kawamura, Tadao and Isoshima, Akira and Yasue, Masaharu and Takayoshi Kobayashi, Mitsuhiko Hokari and Kawai, Kensuke and Maehara, Taketoshi and Noguchi, Makoto and Hoshino, Haruhiko and Hiyama, Hirofumi and Yoshida, Kensaku and Yoshida, Kazunari and Utsugi, Osamu and Takeda, Yasuaki and Takeda, Yuu and Tamaki, Kouichi and Karasudani, Hirohide and Urabe, Takao and Kobayashi, Nozomu and Kobayashi, Shiro and Nakamura, Yusaku and Nakamura, Kazuhito and Nakamura, Michio and Nakamura, Yoshinari and Koguchi, Yorio and Ono, Junichi and Suda, Sumio and Hadeishi, Hiromu and Fukutake, Toshio and Wakui, Kenji and Tanno, Hirokazu and Ishige, Naoki and Ohasi, Takashi and ... and J-ASPECT Study Collaborators
World Neurosurgery, ISSN 1878-8750, 10/2019, Volume 130, pp. e26 - e46
The epidemiology of patients with traumatic brain injury (TBI) has changed dramatically over recent decades as a result of rapid advances in aging societies.... 
Aging | Hospital mortality | Prognosis | Traumatic brain injury | Subdural hematoma
Journal Article
by Aharonian, Felix and Akamatsu, Hiroki and Akimoto, Fumie and Allen, Steven W and Anabuki, Naohisa and Angelini, Lorella and Arnaud, Keith and Audard, Marc and Awaki, Hisamitsu and Axelsson, Magnus and Bamba, Aya and Bautz, Marshall and Blandford, Roger and Brenneman, Laura and Brown, Gregory V and Bulbul, Esra and Cackett, Edward and Chernyakova, Maria and Chiao, Meng and Coppi, Paolo and Costantini, Elisa and De Plaa, Jelle and Den Herder, Jan-Willem and Done, Chris and Dotani, Tadayasu and Ebisawa, Ken and Eckart, Megan and Enoto, Teruaki and Ezoe, Yuichiro and Fabian, Andrew C and Ferrigno, Carlo and Foster, Adam and Fujimoto, Ryuichi and Fukazawa, Yasushi and Furuzawa, Akihiro and Galeazzi, Massimiliano and Gallo, Luigi and Gandhi, Poshak and Giustini, Margherita and Goldwurm, Andrea and Gu, Liyi and Guainazzi, Matteo and Haba, Yoshito and Hagino, Kouichi and Hamaguchi, Kenji and Harrus, Ilana and Hatsukade, Isamu and Hayashi, Katsuhiro and Hayashi, Takayuki and Hayashida, Kiyoshi and Hiraga, Junko and Hornschemeier, Ann and Hoshino, Akio and Hughes, John and Iizuka, Ryo and Inoue, Hajime and Inoue, Yoshiyuki and Ishibashi, Kazunori and Ishida, Manabu and Ishikawa, Kumi and Ishisaki, Yoshitaka and Itoh, Masayuki and Iyomoto, Naoko and Kaastra, Jelle and Kallman, Timothy and Kamae, Tuneyoshi and Kara, Erin and Kataoka, Jun and Katsuda, Satoru and Katsuta, Junichiro and Kawaharada, Madoka and Kawai, Nobuyuki and Kelley, Richard and Khangulyan, Dmitry and Kilbourne, Caroline and King, Ashley and Kitaguchi, Takao and Kitamoto, Shunji and Kitayama, Tetsu and Kohmura, Takayoshi and Kokubun, Motohide and Koyama, Shu and Koyama, Katsuji and Kretschmar, Peter and Krimm, Hans and Kubota, Aya and Kunieda, Hideyo and Laurent, Philippe and Lebrun, François and Lee, Shiu-Hang and Leutenegger, Maurice and Limousin, Olivier and Loewenstein, Michael and Long, Knox S and Lumb, David and Madejski, Grzegorz and Maeda, Yoshitomo and Maier, Daniel and Makishima, Kazuo and Markevitch, Maxim and ... and Hitomi Collaboration and SLAC National Accelerator Lab., Menlo Park, CA (United States)
Nature, ISSN 0028-0836, 07/2016, Volume 535, Issue 7610, pp. 117 - 121
Clusters of galaxies are the most massive gravitationally bound objects in the Universe and are still forming. They are thus important probes(1) of... 
NGC 1275 | GALAXY CLUSTERS | TURBULENT VELOCITY | MULTIDISCIPLINARY SCIENCES | LINE | GAS | NGC-1275 | CONSTRAINTS | X-RAY SPECTROSCOPY | XMM-NEWTON | FEEDBACK | Clusters | Observations | Stars | Cosmology | Astrophysics | Velocity | Stars & galaxies | ASTRONOMY AND ASTROPHYSICS | GRQC | ASTRO
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2009, Volume 106, Issue 34, pp. 14514 - 14517
Cancer surgery requires the complete and precise identification of malignant tissue margins including the smallest disseminated lesions. Internal green... 
Carcinoma | Navigation | Imaging | Colorectal cancer | Fluorescence | Viruses | Lesions | Tumors | Nodules | Cancer | Adenovirus | Green fluorescent protein | Metastasis | GASTROINTESTINAL CANCER | metastasis | MULTIDISCIPLINARY SCIENCES | MOUSE | MICE | CARCINOMATOSIS | FLUORESCENT PROTEINS | green fluorescent protein | PERIOPERATIVE INTRAPERITONEAL CHEMOTHERAPY | PERITONEAL SURFACE COMPONENT | Humans | Transplantation, Heterologous | Green Fluorescent Proteins - genetics | Recombinant Fusion Proteins - metabolism | Neoplasms, Experimental - pathology | Adenoviridae - genetics | Telomerase - metabolism | Green Fluorescent Proteins - chemistry | Neoplasms, Experimental - surgery | Minimally Invasive Surgical Procedures - methods | Peritoneal Neoplasms - pathology | Cell Line | Green Fluorescent Proteins - metabolism | Reproducibility of Results | HCT116 Cells | Peritoneal Neoplasms - surgery | Recombinant Fusion Proteins - chemistry | HT29 Cells | Animals | Mice, Nude | Peritoneal Neoplasms - metabolism | Cell Line, Tumor | Recombinant Fusion Proteins - genetics | Mice | Neoplasms, Experimental - metabolism | Microscopy, Fluorescence | Physiological aspects | Diagnosis | Research | Adenoviruses | Animal models | Transcription | Lung cancer | Data processing | Colon cancer | Surgery | Illumination | Pleural cavity | Peritoneum | Biological Sciences
Journal Article
Arthroscopy: The Journal of Arthroscopic and Related Surgery, ISSN 0749-8063, 2015, Volume 32, Issue 5, pp. 851 - 859
Journal Article
Journal Article
Cancer, ISSN 0008-543X, 05/2017, Volume 123, Issue 9, pp. 1576 - 1584
BACKGROUND There are limited options for the curative treatment of refractory bone and soft tissue sarcomas. The purpose of this phase 1/2 study was to assess... 
clinical trial | tumor lysate | dendritic cells | sarcoma | immunotherapy | CANCER PATIENTS | STAGE IV MELANOMA | CLINICAL-TRIAL | VACCINATION | SUPPORTIVE CARE | HEPATOCELLULAR-CARCINOMA | ONCOLOGY | STREPTOCOCCAL PREPARATION OK-432 | REGULATORY T-CELLS | GENERATION | RELAPSED OSTEOSARCOMA | Interleukin-4 | Immunotherapy - methods | Dendritic Cells | Bone Neoplasms - therapy | Humans | Middle Aged | Male | Leukocytes, Mononuclear | Sarcoma - blood | Sarcoma - therapy | Young Adult | Interleukin-12 - blood | Picibanil | Chondrosarcoma - blood | Adult | Female | Histiocytoma, Malignant Fibrous - therapy | Bone Neoplasms - blood | Child | Osteosarcoma - blood | Soft Tissue Neoplasms - therapy | Leiomyosarcoma - blood | Sarcoma, Clear Cell - blood | Sarcoma, Synovial - therapy | Soft Tissue Neoplasms - blood | Antineoplastic Agents | Treatment Outcome | Chondrosarcoma - therapy | Tumor Necrosis Factor-alpha | Leiomyosarcoma - therapy | Disease-Free Survival | Sarcoma, Synovial - blood | Adolescent | Aged | Histiocytoma, Malignant Fibrous - blood | Sarcoma, Clear Cell - therapy | Granulocyte-Macrophage Colony-Stimulating Factor | Osteosarcoma - therapy | Interferon-gamma - blood | Cancer patients | Usage | Dendritic cells | Immunotherapy | Research | Tumor lysis syndrome | Diagnosis | Health aspects | Therapy | Toxicity | Interleukin | Medical services | Leukocytes (mononuclear) | Macrophages | Metastases | Interleukin 4 | Immunology | Peripheral blood mononuclear cells | Colony-stimulating factor | Cell survival | Immune response | Sarcoma | Granulocyte-macrophage colony-stimulating factor | Soft tissue sarcoma | Interleukin 12 | T cell receptors | Injection | Patients | Side effects | Interferon | Bone | Cancer | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 01/2019, Volume 20, Issue 1, p. 170
Journal Article