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Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 3619 - 13
Squamous cell carcinomas (SCCs) are aggressive malignancies. Previous report demonstrated that master transcription factors (TFs) TP63 and SOX2 exhibited... 
LONG NONCODING RNAS | REGENERATIVE PROLIFERATION | MULTIDISCIPLINARY SCIENCES | BINDING PROTEINS | TRANSCRIPTION | C-MYC | EPITHELIAL DEVELOPMENT | P63 | COMPREHENSIVE GENOMIC CHARACTERIZATION | EXPRESSION | CELL CARCINOMA | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | ErbB Receptors - genetics | Gene Expression Regulation, Neoplastic | Phosphatidylinositol 3-Kinases - metabolism | Proto-Oncogene Proteins c-akt - genetics | SOXB1 Transcription Factors - metabolism | SOXB1 Transcription Factors - genetics | Tumor Suppressor Proteins - genetics | Proto-Oncogene Proteins c-akt - metabolism | Promoter Regions, Genetic | Tumor Suppressor Proteins - metabolism | ErbB Receptors - metabolism | MAP Kinase Kinase Kinases - genetics | MAP Kinase Kinase Kinases - metabolism | RNA, Long Noncoding - genetics | Transcription Factors - genetics | Phosphatidylinositol 3-Kinases - genetics | Transcription Factors - metabolism | Xenograft Model Antitumor Assays | Animals | Enhancer Elements, Genetic | Cell Line, Tumor | Mice, Inbred NOD | Squamous cell carcinoma | Transcription factors | Epidermal growth factor receptors | Extracellular signal-regulated kinase | AKT protein | Activation | Gene expression | Ribonucleic acid--RNA | 1-Phosphatidylinositol 3-kinase | Proteins | Enhancers | Phenotyping | Tumorigenesis | Localization | Non-coding RNA | Deoxyribonucleic acid--DNA | Cancer
Journal Article
Nature Genetics, ISSN 1061-4036, 2014, Volume 46, Issue 8, pp. 866 - 871
Journal Article
PLoS Genetics, ISSN 1553-7390, 03/2018, Volume 14, Issue 3, p. e1007277
Journal Article
Oncology Reports, ISSN 1021-335X, 07/2012, Volume 28, Issue 1, pp. 55 - 61
Journal Article
EMBO reports, ISSN 1469-221X, 01/2018, Volume 19, Issue 1, pp. 73 - 88
p63, more specifically its ΔNp63α isoform, plays essential roles in squamous cell carcinomas (SCCs), yet the mechanisms controlling its nuclear transport... 
STEM-CELLS | EPIDERMAL DIFFERENTIATION | LOCALIZATION SIGNAL | EPITHELIAL-CELLS | CANCER CELLS | REGENERATIVE PROLIFERATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PORE COMPLEX COMPOSITION | SELF-RENEWAL | TARGET GENE | HUMAN KERATINOCYTES | CELL BIOLOGY | Phosphorylation | Cell Proliferation | Membrane Glycoproteins - metabolism | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Gene Expression Regulation, Neoplastic | Uterine Cervical Neoplasms - pathology | Head and Neck Neoplasms - metabolism | Nuclear Pore Complex Proteins - genetics | Cell Nucleus - metabolism | Uterine Cervical Neoplasms - metabolism | rho-Associated Kinases - metabolism | HEK293 Cells | Female | Cell Differentiation | Membrane Proteins - metabolism | Rho Guanine Nucleotide Exchange Factors - metabolism | Active Transport, Cell Nucleus - genetics | Skin Neoplasms - pathology | Amino Acid Sequence | Signal Transduction | Atlases as Topic | Membrane Proteins - genetics | Nuclear Pore Complex Proteins - metabolism | Computational Biology | rho-Associated Kinases - genetics | Rho Guanine Nucleotide Exchange Factors - genetics | Uterine Cervical Neoplasms - genetics | Head and Neck Neoplasms - pathology | Membrane Glycoproteins - genetics | Skin Neoplasms - metabolism | Skin Neoplasms - genetics | Cell Line, Tumor | Cytosol - metabolism | Head and Neck Neoplasms - genetics | Cell proliferation | Squamous cell carcinoma | Phenylalanine | Imports | Glycine | Kinases | Nuclear transport | Rho-associated kinase | Proteins | Nucleoporins | Cell fate | Transport | Differentiation | Membrane & Intracellular Transport | Cancer
Journal Article
Gut, ISSN 0017-5749, 08/2017, Volume 66, Issue 8, pp. 1358 - 1368
ObjectivesOesophageal squamous cell carcinoma (OSCC) is an aggressive malignancy and the major histological subtype of oesophageal cancer. Although recent... 
ONCOGENES | OESOPHAGEAL CANCER | CANCER | CELL BIOLOGY | RNA-POLYMERASE-II | CANCER-CELLS | HSP90 INHIBITOR | SIGNALING PATHWAY | TRANSCRIPTION | COVALENT CDK7 INHIBITOR | PROLIFERATION | DIFFERENTIATION | GASTROENTEROLOGY & HEPATOLOGY | TUMOR-GROWTH | CONTRIBUTES | Neoplasm Transplantation | Gene Expression - drug effects | Carcinoma, Squamous Cell - genetics | Humans | Transcriptome | Gene Expression Profiling | Female | Antineoplastic Agents - pharmacology | Sterol Regulatory Element Binding Protein 2 - genetics | Cyclin-Dependent Kinases - antagonists & inhibitors | Acrylamides - pharmacology | Oncogenes - genetics | p21-Activated Kinases - genetics | HSP40 Heat-Shock Proteins - genetics | Phosphoproteins - genetics | Pyrimidines - pharmacology | Animals | Carcinoma, Squamous Cell - drug therapy | High-Throughput Screening Assays | Sequence Analysis, RNA | Esophageal Neoplasms - genetics | Aminopyridines - pharmacology | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Phenylenediamines - pharmacology | Cell Proliferation - drug effects | Mice | Core Binding Factor Alpha 2 Subunit - genetics | Esophageal Neoplasms - drug therapy | Drug Screening Assays, Antitumor | Reports | Squamous cell carcinoma | Research | Oncogenes | Esophageal cancer | Transcription factors | Chromatin | Phenotypes | Immunoprecipitation | Genomic analysis | Pathogenesis | Medical innovations | Runx1 protein | Genomes | Malignancy | Metastasis | Gene expression | Kinases | Ribonucleic acid--RNA | Esophagus | Yes-associated protein | Medical prognosis | Drug dosages | Tumors
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2017, Volume 114, Issue 15, pp. 3981 - 3986
ZBTB transcription factors orchestrate gene transcription during tissue development. However, their roles in glioblastoma (GBM) remain unexplored. Here,... 
BCL6 | NCoR | AXL | Glioblastoma multiforme | ZBTB | glioblastoma multiforme | MULTIDISCIPLINARY SCIENCES | CELL-GROWTH | BTB DOMAIN | BREAST-CANCER | B-CELLS | IN-VITRO | GROWTH ARREST | PROBE LEVEL | INHIBITOR | HUMAN GLIOBLASTOMA-MULTIFORME | Biological Sciences
Journal Article
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 05/2017, Volume 114, Issue 21, pp. E4317 - E4317
Journal Article
CELL DIVISION, ISSN 1747-1028, 08/2019, Volume 14, Issue 1, pp. 7 - 13
Background Nuclear pore complexes (NPCs) act as nano-turnstiles within nuclear membranes between the cytoplasm and nucleus of mammalian cells. NPC proteins,... 
CELLS | Mitosis | SPINDLE | Cytokinesis | Nup58 | CELL BIOLOGY | Midbody | COHESIN SUBUNIT SMC1 | NUCLEAR-PORE COMPLEX | NUP62 | DYNAMICS | SUBCOMPLEX | RAE1 | CONTRIBUTES | Centrosome
Journal Article