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1. Full Text Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls
by Flannick, Jason and Mercader, Josep M and Fuchsberger, Christian and Udler, Miriam S and Mahajan, Anubha and Wessel, Jennifer and Teslovich, Tanya M and Caulkins, Lizz and Koesterer, Ryan and Barajas-Olmos, Francisco and Blackwell, Thomas W and Boerwinkle, Eric and Brody, Jennifer A and Centeno-Cruz, Federico and Chen, Ling and Chen, Siying and Contreras-Cubas, Cecilia and Córdova, Emilio and Correa, Adolfo and Cortes, Maria and DeFronzo, Ralph A and Dolan, Lawrence and Drews, Kimberly L and Elliott, Amanda and Floyd, James S and Gabriel, Stacey and Garay-Sevilla, Maria Eugenia and García-Ortiz, Humberto and Gross, Myron and Han, Sohee and Heard-Costa, Nancy L and Jackson, Anne U and Jørgensen, Marit E and Kang, Hyun Min and Kelsey, Megan and Kim, Bong-Jo and Koistinen, Heikki A and Kuusisto, Johanna and Leader, Joseph B and Linneberg, Allan and Liu, Ching-Ti and Liu, Jianjun and Lyssenko, Valeriya and Manning, Alisa K and Marcketta, Anthony and Malacara-Hernandez, Juan Manuel and Martínez-Hernández, Angélica and Matsuo, Karen and Mayer-Davis, Elizabeth and Mendoza-Caamal, Elvia and Mohlke, Karen L and Morrison, Alanna C and Ndungu, Anne and Ng, Maggie C. Y and O’Dushlaine, Colm and Payne, Anthony J and Pihoker, Catherine and Post, Wendy S and Preuss, Michael and Psaty, Bruce M and Vasan, Ramachandran S and Rayner, N. William and Reiner, Alexander P and Revilla-Monsalve, Cristina and Robertson, Neil R and Santoro, Nicola and Schurmann, Claudia and So, Wing Yee and Soberón, Xavier and Stringham, Heather M and Strom, Tim M and Tam, Claudia H. T and Thameem, Farook and Tomlinson, Brian and Torres, Jason M and Tracy, Russell P and van Dam, Rob M and Vujkovic, Marijana and Wang, Shuai and Welch, Ryan P and Witte, Daniel R and Wong, Tien-Yin and Atzmon, Gil and Barzilai, Nir and Blangero, John and Bonnycastle, Lori L and Bowden, Donald W and Chambers, John C and Chan, Edmund and Cheng, Ching-Yu and Cho, Yoon Shin and Collins, Francis S and de Vries, Paul S and Duggirala, Ravindranath and Glaser, Benjamin and Gonzalez, Clicerio and Gonzalez, Ma Elena and Groop, Leif and Kooner, Jaspal Singh and Kwak, Soo Heon and ... and DiscovEHR Collaboration and ESP and GoT2D and SIGMA-T2D and Broad Genomics Platform and AMP-T2D-GENES and LuCamp and T2D-GENES and CHARGE and ProDiGY
Nature (London), ISSN 0028-0836, 06/2019, Volume 570, Issue 7759, pp. 71 - 76
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Genome-Wide Association Study | Diabetes Mellitus, Type 2 - genetics | Gene Frequency | Humans | Decision Support Techniques | Male | Case-Control Studies | Mice, Knockout | Whole Exome Sequencing | Exome - genetics | Animals | Female | Mice | Type 2 diabetes | Genetic research | Genetic aspects | Research | Exome sequencing | Sequences | Disease | Pathogenesis | Genes | Diabetes mellitus | Hispanic Americans | Health risks | Genomes | Epidemiology | Disease control | Studies | Proteins | Genetic variance | Gene frequency | Alleles | Heritability | Gene loci | Diabetes | Diabetes mellitus (non-insulin dependent) | Power | Index Medicus | Clinical Medicine | Medicinsk genetik | Basic Medicine | Medical Genetics | Endokrinologi och diabetes | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Mus | Klinisk medicin | Endocrinology and Diabetes
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2. Full Text Revisit Population-based and Family-based Genotype Imputation
by Liu, Ching-Ti and Deng, Xuan and Fisher, Virginia and Heard-Costa, Nancy and Xu, Hanfei and Zhou, Yanhua and Vasan, Ramachandran S and Cupples, L. Adrienne
Scientific reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1800 - 1800
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Genotype & phenotype | Accuracy | Pedigree | Linkage disequilibrium | Population studies | Heritability | Heredity | Genomes | Genotypes | Index Medicus
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3. Full Text Association of Maternal Prepregnancy Weight with Offspring Adiposity Throughout Adulthood over 37 Years of Follow‐up
by Schoppa, Isabelle and Lyass, Asya and Heard‐Costa, Nancy and de Ferranti, Sarah D and Fox, Caroline and Gillman, Matthew W and D’Agostino, Ralph and Levy, Daniel and Mendelson, Michael M
Obesity (Silver Spring, Md.), ISSN 1930-7381, 01/2019, Volume 27, Issue 1, pp. 137 - 144
Endocrinology & Metabolism | Life Sciences & Biomedicine | Nutrition & Dietetics | Science & Technology | Follow-Up Studies | Gestational Weight Gain - physiology | Humans | Risk Factors | Adult | Female | Male | Obesity - etiology | Adiposity - genetics | Longitudinal Studies | Cohort Studies | Obesity - pathology | Obesity | Cardiovascular disease | Pregnancy | Studies | Hypotheses | Weight control | Questionnaires | DNA methylation | Epigenetics | Adults | Diabetes | Health risk assessment | Age | Index Medicus
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4. Full Text Sequence Kernel Association Test for Survival Traits
by Chen, Han and Lumley, Thomas and Brody, Jennifer and Heard‐Costa, Nancy L and Fox, Caroline S and Cupples, L. Adrienne and Dupuis, Josée
Genetic epidemiology, ISSN 0741-0395, 04/2014, Volume 38, Issue 3, pp. 191 - 197
likelihood ratio test | variance component test | Cox proportional hazard model | rare variant analysis | Rare variant analysis | Variance component test | Likelihood ratio test | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Mathematical & Computational Biology | Heart | Genetic Association Studies | Humans | Proportional Hazards Models | Genotype | Logistic Models | Obesity - genetics | Survival | Phenotype | Time Factors | Survival Analysis | Polymorphism, Single Nucleotide - genetics | Models, Genetic | Software | Research Design | Cohort Studies | Medical tests | Analysis | Statistics | Regression analysis | Index Medicus
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5. Full Text Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies
by Joehanes, Roby and Zhang, Xiaoling and Huan, Tianxiao and Yao, Chen and Ying, Sai-xia and Nguyen, Quang Tri and Demirkale, Cumhur Yusuf and Feolo, Michael L and Sharopova, Nataliya R and Sturcke, Anne and Schäffer, Alejandro A and Heard-Costa, Nancy and Chen, Han and Liu, Po-ching and Wang, Richard and Woodhouse, Kimberly A and Tanriverdi, Kahraman and Freedman, Jane E and Raghavachari, Nalini and Dupuis, Josée and Johnson, Andrew D and O'Donnell, Christopher J and Levy, Daniel and Munson, Peter J
Genome Biology, ISSN 1474-7596, 01/2017, Volume 18, Issue 1, pp. 16 - 16
Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Gene Expression | Genetic Predisposition to Disease | Reproducibility of Results | Gene Frequency | Humans | Middle Aged | Regulatory Sequences, Nucleic Acid | Male | Gene Expression Profiling | Alleles | Adult | Female | Aged | MicroRNAs - genetics | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Genomics - methods | Quantitative Trait Loci | Web Browser | Cluster Analysis | Phenotypes | Disease | Genomics | Coronary artery | Genomes | Single-nucleotide polymorphism | Gene expression | Blood | Quantitative trait loci | Studies | DNA microarrays | DNA methylation | Lead | miRNA | Heart diseases | Polymorphism | Index Medicus
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6. Full Text Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment
by Nagtegaal, Paul and Broer, L and Zilhao, N.R and Jakobsdottir, Margret and Bishop, C.E and Brumat, M and Christiansen, M.W and Cocca, Massimiliano and Gao, Y and Heard-Costa, N.L and Evans, Daniel and Pankratz, Shane and Pratt, S.R and Price, T.R and Spankovich, C and Stimson, M.R and Valle, K and Vuckovic, gana and Wells, H and Eiriksdottir, Gudny and Fransen, Erik and Ikram, Arfan and Li, C.-M and Longstreth, W.T and Steves, Claire and Camp, Guy and Correa, D.D and Cruickshanks, Karen and Gasparini, Paolo and Girotto, S and Deloukas, Panagiotis and Nalls, Michael and Schweinfurth, J.M and Seshai, Sudha and Sotoodehnia, Nona and Tranah, Gregory and Uitterlinden, Ané and Wilson, James and Gudnason, Vilmundur and Hoffman, H.J and Williams, Frances and Goedegebure, Ane
Scientific reports, ISSN 2045-2322, 10/2019, Volume 9, Issue 1, pp. 15192 - 10
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Phenotypes | Reviews | Hair cells | Aging | Single-nucleotide polymorphism | Genomes | Hearing protection | Hearing impairment | Inner ear | Age | Hearing loss | Index Medicus
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7. Full Text Trends in the association of parental history of obesity over 60 years
by Fox, Caroline S and Pencina, Michael J and Heard‐Costa, Nancy L and Shrader, Peter and Jaquish, Cashell and O'Donnell, Christopher J and Vasan, Ramachandran S and Cupples, L. Adrienne and D'Agostino, Ralph B
Obesity (Silver Spring, Md.), ISSN 1930-7381, 03/2014, Volume 22, Issue 3, pp. 919 - 924
Endocrinology & Metabolism | Life Sciences & Biomedicine | Nutrition & Dietetics | Science & Technology | Body Mass Index | Genetic Predisposition to Disease | Prevalence | United States | Humans | Middle Aged | Risk Factors | Parents | Male | Obesity - genetics | Obesity - epidemiology | Weight Gain - genetics | Adult | Female | Longitudinal Studies | Obesity | Body mass index | Weight control | Health risk assessment | Index Medicus | epidemiology | Framingham Heart Study | weight change | family history | obesity
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8. Full Text Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation
by Chu, Audrey Y and Deng, Xuan and Fisher, Virginia A and Drong, Alexander and Zhang, Yang and Feitosa, Mary F and Liu, Ching-Ti and Weeks, Olivia and Choh, Audrey C and Duan, Qing and Dyer, Thomas D and Eicher, John D and Guo, Xiuqing and Heard-Costa, Nancy L and Kacprowski, Tim and Kent, Jack W and Lange, Leslie A and Liu, Xinggang and Lohman, Kurt and Lu, Lingyi and Mahajan, Anubha and O'Connell, Jeffrey R and Parihar, Ankita and Peralta, Juan M and Smith, Albert V and Zhang, Yi and Homuth, Georg and Kissebah, Ahmed H and Kullberg, Joel and Laqua, René and Launer, Lenore J and Nauck, Matthias and Olivier, Michael and Peyser, Patricia A and Terry, James G and Wojczynski, Mary K and Yao, Jie and Bielak, Lawrence F and Blangero, John and Borecki, Ingrid B and Bowden, Donald W and Carr, John Jeffrey and Czerwinski, Stefan A and Ding, Jingzhong and Friedrich, Nele and Gudnason, Vilmunder and Harris, Tamara B and Ingelsson, Erik and Johnson, Andrew D and Kardia, Sharon L.R and Langefeld, Carl D and Lind, Lars and Liu, Yongmei and Mitchell, Braxton D and Morris, Andrew P and Mosley, Thomas H and Rotter, Jerome I and Shuldiner, Alan R and Towne, Bradford and Völzke, Henry and Wallaschofski, Henri and Wilson, James G and Allison, Matthew and Lindgren, Cecilia M and Goessling, Wolfram and Cupples, L Adrienne and Steinhauser, Matthew L and Fox, Caroline S
Nature genetics, ISSN 1061-4036, 01/2017, Volume 49, Issue 1, pp. 125 - 130
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Predisposition to Disease | Genome-Wide Association Study | Humans | Mice, Inbred C57BL | Genetic Loci - genetics | Adipocytes - cytology | Male | Obesity - genetics | Phenotype | Animals | Ethnic Groups - genetics | Adipocytes - metabolism | Genetic Markers - genetics | Polymorphism, Single Nucleotide - genetics | Female | Cell Differentiation | Mice | Body Fat Distribution | Cohort Studies | Adipose tissues | Genome-wide association studies | Usage | Magnetic resonance imaging | Analysis | Heart | Women | Genealogy | Medical imaging | Nuclear magnetic resonance--NMR | Body fat | Genomes | Adipocytes | Metabolism | Body mass index | Mens health | Rodents | Quality | Index Medicus | adipocyte development | GWAS | differentiation | ectopic fat | obesity
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