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Nature, ISSN 0028-0836, 06/2017, Volume 546, Issue 7658, pp. 357 - 358
Cellular metabolism is tightly coordinated with the needs of the existing cellular state. Dividing cells must duplicate their cellular components and... 
Proteins | Enzymes | Cell cycle | Cell division | Lipids | Division | Lipid metabolism | Metabolism | Kinases | Deoxyribonucleic acid--DNA | Apoptosis
Journal Article
Science, ISSN 0036-8075, 9/2010, Volume 329, Issue 5998, pp. 1492 - 1499
Journal Article
Nature Cell Biology, ISSN 1465-7392, 11/2015, Volume 17, Issue 12, pp. 1515 - 1517
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 2012, Volume 8, Issue 10, pp. 839 - 847
Cancer cells engage in a metabolic program to enhance biosynthesis and support cell proliferation. The regulatory properties of pyruvate kinase M2 (PKM2)... 
ISOZYME | INHIBITION | FRUCTOSE-1,6-BISPHOSPHATE | THYROID-HORMONE | CONVERSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ISOFORM | BINDING PROTEIN | CANCER-CELL METABOLISM | TUMOR-GROWTH | NUCLEAR TRANSLOCATION | Genes | Cells | Cancer | Tumors | Index Medicus | BASIC BIOLOGICAL SCIENCES
Journal Article
Molecular Cancer Research, ISSN 1541-7786, 01/2016, Volume 14, Issue 1 Supplement, pp. IA23 - IA23
Journal Article
Nature Cell Biology, ISSN 1465-7392, 09/2017, Volume 19, Issue 9, pp. 1017 - 1026
Although normally dormant, hair follicle stem cells (HFSCs) quickly become activated to divide during a new hair cycle. The quiescence of HFSCs is known to be... 
MORPHOGENESIS | MITOCHONDRIAL PYRUVATE CARRIER | METABOLISM | QUIESCENCE | C-MYC | NICHE | SKIN | INDUCTION | EXPRESSION | CYCLE | CELL BIOLOGY | L-Lactate Dehydrogenase - metabolism | Mitochondrial Membrane Transport Proteins - antagonists & inhibitors | Cellular Senescence - drug effects | Male | Glycolysis - drug effects | Mitochondrial Membrane Transport Proteins - genetics | Anion Transport Proteins - antagonists & inhibitors | Stem Cells - enzymology | Time Factors | Isoenzymes - metabolism | Acrylates - pharmacology | Female | Mitochondrial Membrane Transport Proteins - metabolism | Signal Transduction | Isoenzymes - genetics | Lactic Acid - metabolism | Mice, Inbred C57BL | Genotype | Hair Follicle - enzymology | Isoenzymes - deficiency | Anion Transport Proteins - metabolism | Proto-Oncogene Proteins c-myc - metabolism | Mice, Knockout | Hair Follicle - drug effects | Hair Follicle - cytology | Phenotype | Animals | L-Lactate Dehydrogenase - genetics | L-Lactate Dehydrogenase - deficiency | Stem Cells - drug effects | Cell Proliferation - drug effects | Anion Transport Proteins - genetics | Cell metabolism | Lactate dehydrogenase | Genetic aspects | Hair follicles | Health aspects | Stem cells | Hair | Dehydrogenases | Pyruvic acid | Epidermis | Activation | Myc protein | Dehydrogenase | Metabolism | L-Lactate dehydrogenase | Mitochondria | Cell activation | Clonal deletion | Glycolysis | Deletion | Lactic acid | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 11/2015, Volume 6, Issue 1, pp. 8873 - 8873
Viruses rewire host cell glucose and glutamine metabolism to meet the bioenergetic and biosynthetic demands of viral propagation. However, the mechanism by... 
PATHWAY | METABOLIC-RESPONSES | GLUCOSE | MULTIDISCIPLINARY SCIENCES | INFECTION | CELL-GROWTH | REDUCTIVE CARBOXYLATION | Cell Line | Humans | Glutamine - metabolism | Adenoviridae - physiology | Proto-Oncogene Proteins c-myc - genetics | Mutation | Proto-Oncogene Proteins c-myc - metabolism | Virus Replication - physiology | Index Medicus
Journal Article
Nature Cell Biology, ISSN 1465-7392, 09/2017, Volume 19, Issue 9, pp. 1027 - 1036
Most differentiated cells convert glucose to pyruvate in the cytosol through glycolysis, followed by pyruvate oxidation in the mitochondria. These processes... 
COLON-CANCER | PROGENITORS | INHIBITION | TCA CYCLE | GROWTH | VALPROIC ACID | DIFFERENTIATION | IDENTIFICATION | ADULT DROSOPHILA MIDGUT | CARRIER | CELL BIOLOGY | Intestines - drug effects | Mitochondrial Membrane Transport Proteins - antagonists & inhibitors | Receptors, G-Protein-Coupled - metabolism | Humans | Intestines - metabolism | Drosophila Proteins - metabolism | Stem Cells - metabolism | Mitochondrial Membrane Transport Proteins - genetics | Drosophila melanogaster - metabolism | Transfection | Anion Transport Proteins - antagonists & inhibitors | RNA Interference | Time Factors | Mitochondrial Proteins - metabolism | Acrylates - pharmacology | Pyruvic Acid - metabolism | Cell Differentiation | Mitochondrial Membrane Transport Proteins - metabolism | Signal Transduction | Tissue Culture Techniques | Lactic Acid - metabolism | Cells, Cultured | Drosophila melanogaster - cytology | Genotype | Mitochondria - metabolism | Mitochondria - drug effects | Anion Transport Proteins - metabolism | Mice, Knockout | Phenotype | Animals | Glycolysis | Stem Cells - drug effects | Cell Proliferation - drug effects | Receptors, G-Protein-Coupled - genetics | Drosophila Proteins - genetics | Anion Transport Proteins - genetics | Intestines - cytology | Cell proliferation | Drosophila | Pyruvic acid | Metabolism | Cytosol | Mitochondria | Clonal deletion | Organoids | Intestine | Stem cells | Deletion | Oxidation | Differentiation | Cancer | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 04/2013, Volume 496, Issue 7443, pp. 38 - 40
[...]the addition of cell-membrane-permeable (R)-2HG to cells without an IDH mutation had the same effects, indicating that this metabolite is the transforming... 
Proteins | DNA methylation | Epigenetics | Mutation
Journal Article