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Cell Metabolism, ISSN 1550-4131, 02/2017, Volume 25, Issue 2, p. 223
Diabetes is a growing epidemic, and many patients depend on insulin injections to control the disease and minimize long-term complications. In a recent... 
Pancreatic beta cells | Genetically modified organisms
Journal Article
Cell Metabolism, ISSN 1550-4131, 02/2017, Volume 25, Issue 2, pp. 223 - 224
Diabetes is a growing epidemic, and many patients depend on insulin injections to control the disease and minimize long-term complications. In a recent... 
IN-VITRO | ENDOCRINOLOGY & METABOLISM | CELL BIOLOGY | Cell Line | Animals | Diabetes Mellitus, Experimental | Humans | Blood Glucose | Mice | Insulin - genetics | Insulin-Secreting Cells | Index Medicus
Journal Article
Pancreatology, ISSN 1424-3903, 03/2014, Volume 14, Issue 2, p. e5
  While functional studies delineating the exact function of pancreatic mesenchyme in the adult pancreas are missing, the fact that mesenchymal cells reside... 
Stem cells | Diabetes | Pancreas
Journal Article
Current Opinion in Genetics & Development, ISSN 0959-437X, 06/2015, Volume 32, p. 171
The Islets of Langerhans are crucial 'micro-organs' embedded in the glandular exocrine pancreas that regulate nutrient metabolism. They not only synthesize,... 
Analysis | Stem cells | Insulin
Journal Article
The EMBO Journal, ISSN 0261-4189, 07/2015, Volume 34, Issue 13, pp. 1759 - 1772
Journal Article
Cell, ISSN 0092-8674, 09/2012, Volume 150, Issue 6, p. 1103
[beta] cell dysfunction with subsequent apoptosis is considered a significant contributor to the development of type 2 diabetes. Emerging data from Talchai et... 
Type 2 diabetes | Pancreatic beta cells
Journal Article
Nature Medicine, ISSN 1078-8956, 05/2016, Volume 22, Issue 5, pp. 497 - 505
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2011, Volume 108, Issue 41, pp. 17010 - 17015
Although Hedgehog (Hh) signaling regulates cell differentiation during pancreas organogenesis, the consequences of pathway upregulation in adult β-cells in... 
Beta cells | Transcription factors | Phenotypes | Transgenic animals | Genes | Islet cells | Adults | Pancreas | Insulin | Cilia | Signaling pathways | Embryogenesis | Progenitor | Glucose stimulated insulin secretion | PANCREAS DEVELOPMENT | PROGENITORS | MULTIDISCIPLINARY SCIENCES | INSULIN-SECRETION | progenitor | PROLIFERATION | ADULT HUMAN | PRIMARY CILIUM | glucose stimulated insulin secretion | IN-VITRO | embryogenesis | signaling pathways | GENE | SOX9 | EXPRESSION | Cilia - physiology | Glucose Intolerance - metabolism | Up-Regulation | Pancreatic Neoplasms - metabolism | Pancreatic Neoplasms - etiology | Homeodomain Proteins - metabolism | Zinc Finger Protein Gli2 | Transcriptome | Hedgehog Proteins - metabolism | Male | Insulin-Secreting Cells - metabolism | Glucose Intolerance - etiology | Kruppel-Like Transcription Factors - metabolism | Trans-Activators - genetics | Insulin-Secreting Cells - cytology | Nuclear Proteins - genetics | Recombinant Proteins - metabolism | SOX9 Transcription Factor - metabolism | Glucose Intolerance - genetics | Cell Dedifferentiation - physiology | Signal Transduction | Pancreatic Neoplasms - pathology | Mice, Transgenic | Nuclear Proteins - metabolism | Recombinant Proteins - genetics | Transcription Factors - genetics | Homeodomain Proteins - genetics | Cilia - genetics | Transcription Factors - metabolism | Animals | Trans-Activators - metabolism | Mice | Cell Dedifferentiation - genetics | Kruppel-Like Transcription Factors - genetics | SOX9 Transcription Factor - genetics | Index Medicus | Biological Sciences
Journal Article
Diabetes, ISSN 0012-1797, 05/2013, Volume 62, Issue 5, pp. 1581 - 1592
Journal Article
Nature Cell Biology, ISSN 1465-7392, 2014, Volume 16, Issue 3, pp. 255 - 267
Journal Article
Nature Reviews Endocrinology, ISSN 1759-5029, 2014, Volume 10, Issue 5, pp. 253 - 255
Journal Article
Nature Reviews. Endocrinology, ISSN 1759-5029, 05/2014, Volume 10, Issue 5, p. 253
Journal Article
Nature Reviews Endocrinology, ISSN 1759-5029, 05/2014, Volume 10, Issue 5, p. 253
A genetic analysis of patients with permanent neonatal diabetes mellitus has revealed functional conservation of transc