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by Porcu, E and Medici, M and Pistis, G and Volpato, C.B and Wilson, S.G and Cappola, A.R and Bos, S.D and Deelen, J and Heijer, M. den and Freathy, R.M and Lahti, J and Liu, C and Lopez, L.M and Nolte, I.M and O'Connell, J.R and Tanaka, T and Trompet, S and Arnold, A and Bandinelli, S and Beekman, M and Bohringer, S and Brown, S.J and Buckley, B.M and Camaschella, C and Craen, A.J. de and Davies, G and Visser, M.C.H. de and Ford, I and Forsen, T and Frayling, T.M and Fugazzola, L and Gogele, M and Hattersley, A.T and Hermus, A.R.M.M and Hofman, A and Houwing-Duistermaat, J.J and Jensen, R.A and Kajantie, E and Kloppenburg, M and Lim, E.M and Masciullo, C and Mariotti, S and Minelli, C and Mitchell, B.D and Nagaraja, R and Netea-Maier, R.T and Palotie, A and Persani, L and Piras, M.G and Psaty, B.M and Raikkonen, K and Richards, J.B and Rivadeneira, F and Sala, C and Sabra, M.M and Sattar, N and Shields, B.M and Soranzo, N and Starr, J.M and Stott, D.J and Sweep, F.C and Usala, G and Klauw, M.M. van der and Heemst, D. van and Mullem, A. van and Vermeulen, S and Visser, W.E and Walsh, J.P and Westendorp, R.G.J and Widen, E and Zhai, G and Cucca, F and Deary, I.J and Eriksson, J.G and Ferrucci, L and Fox, C.S and Jukema, J.W and Kiemeney, L.A.L.M and Pramstaller, P.P and Schlessinger, D and Shuldiner, A.R and Slagboom, E.P and Uitterlinden, A.G and Vaidya, B and Visser, T.J and Wolffenbuttel, B.H.R and Meulenbelt, I and Rotter, J.I and Spector, T.D and Hicks, A.A and Toniolo, D and Sanna, S and Peeters, R.P and Naitza, S
PLOS Genetics, ISSN 1553-7390, 2013, Volume 9, Issue 2, p. e1003266
Thyroid hormone is essential for normal metabolism and development, and overt abnormalities in thyroid function lead to common endocrine disorders affecting... 
FACTOR BINDING PROTEIN-5 | VARIANTS | GROWTH | GENETICS & HEREDITY | SERUM TSH | COMMON VARIATION | MUTATIONS | HORMONE PATHWAY GENES | EXPRESSION | GENOME-WIDE ASSOCIATION | THYROTROPIN | Quantitative genetics | Physiological aspects | Genetic aspects | Research | Thyroid hormones | Health aspects | Meta-analysis | Studies | Older people | Thyroid gland | Genomes | Agreements | Hormones | Grants
Journal Article
by Wood, Anew R and Esko, Tonu and Yang, Jian and Vedantam, Sailaja and Pers, Tune H and Gustafsson, Stefan and Chu, Auey Y and Estrada, Karol and Luan, Jian'an and Kutalik, Zoltán and Amin, Najaf and Buchkovich, Martin L and Croteau-Chonka, Damien C and Day, Felix R and Duan, Yanan and Fall, Tove and Fehrmann, Rudolf and Ferreira, Teresa and Jackson, Anne U and Karjalainen, Juha and Lo, Ken Sin and Locke, Adam E and Mägi, Reedik and Mihailov, Evelin and Porcu, Eleonora and Randall, Joshua C and Scherag, Ané and Vinkhuyzen, Anna A. E and Westra, Harm-Jan and Winkler, Thomas W and Workalemahu, Tsegaselassie and Zhao, Jing Hua and Absher, Devin and Albrecht, Eva and Anderson, Denise and Baron, Jeffrey and Beekman, Marian and Demirkan, Ayse and Ehret, Georg B and Feenstra, Bjarke and Feitosa, Mary F and Fischer, Krista and Fraser, Ross M and Goel, Anuj and Gong, Jian and Justice, Anne E and Kanoni, Stavroula and Kleber, Marcus E and Kristiansson, Kati and Lim, Unhee and Lotay, Vaneet and Lui, Julian C and Mangino, Massimo and Mateo Leach, Irene and Medina-Gomez, Carolina and Nalls, Michael A and Nyholt, Dale R and Palmer, Cameron D and Pasko, Dorota and Pechlivanis, Sonali and Prokopenko, Inga and Ried, Janina S and Ripke, Stephan and Shungin, Dmitry and Stancáková, Alena and Strawbridge, Rona J and Sung, Yun Ju and Tanaka, Toshiko and Teumer, Alexander and Trompet, Stella and van der Laan, Sander W and van Setten, Jessica and van Vliet-Ostaptchouk, Jana V and Wang, Zhaoming and Yengo, Loïc and Zhang, Weihua and Afzal, Uzma and Arnlöv, Johan and Arscott, Gillian M and Bandinelli, Stefania and Barrett, Amy and Bellis, Claire and Bennett, Amanda J and Berne, Christian and Blüher, Matthias and Bolton, Jennifer L and Böttcher, Yvonne and Boyd, Heather A and Bruinenberg, Marcel and Buckley, Brendan M and Buyske, Steven and Caspersen, Ida H and Chines, Peter S and Clarke, Robert and Claudi-Boehm, Simone and Cooper, Matthew and Daw, E. Warwick and de Jong, Pim A and Deelen, Joris and Delgado, Graciela and ... and PAGE Consortium and MIGen Consortium and LifeLines Cohort Study and Elect Med Records & Genom eMERGE C and Electronic Medical Records and Genomics (eMEMERGEGE) Consortium and PAGEGE Consortium and The MIGen Consortium and The PAGE Consortium and The Electronic Medical Records and Genomics (eMERGE) Consortium and The LifeLines Cohort Study and Högskolan Dalarna and Akademin Utbildning, hälsa och samhälle and Medicinsk vetenskap
Nature genetics, ISSN 1061-4036, 2014, Volume 46, Issue 11, pp. 1173 - 1186
Journal Article
JOURNAL OF MEDICAL INTERNET RESEARCH, ISSN 1438-8871, 04/2016, Volume 18, Issue 4
Background: Increasing physical activity is a viable strategy for improving both the health and quality of life of older adults. Objective: The aim of this... 
MEDICAL INFORMATICS | HEALTH CARE SCIENCES & SERVICES | Internet | HEALTH | quality of life | EXERCISE | physical activity
Journal Article
by Shungin, Dmitry and Winkler, Thomas W and Croteau-Chonka, Damien C and Ferreira, Teresa and Locke, Adam E and Mägi, Reedik and Strawbridge, Rona J and Pers, Tune H and Fischer, Krista and Justice, Anne E and Workalemahu, Tsegaselassie and Wu, Joseph M. W and Buchkovich, Martin L and Heard-Costa, Nancy L and Roman, Tamara S and ng, Alexander W and Song, Ci and Gustafsson, Stefan and Day, Felix R and Esko, Tonu and Fall, Tove and Kutalik, Zoltán and Luan, Jian'an and Randall, Joshua C and Scherag, Ané and Vedantam, Sailaja and Wood, Anew R and Chen, Jin and Fehrmann, Rudolf and Karjalainen, Juha and Kahali, Bratati and Liu, Ching-Ti and Schmidt, Ellen M and Absher, Devin and Amin, Najaf and Anderson, Denise and Beekman, Marian and Bragg-Gresham, Jennifer L and Buyske, Steven and Demirkan, Ayse and Ehret, Georg B and Feitosa, Mary F and Goel, Anuj and Jackson, Anne U and Johnson, Toby and Kleber, Marcus E and Kristiansson, Kati and Mangino, Massimo and Mateo Leach, Irene and Medina-Gomez, Carolina and Palmer, Cameron D and Pasko, Dorota and Pechlivanis, Sonali and Peters, Marjolein J and Prokopenko, Inga and Stančáková, Alena and Ju Sung, Yun and Tanaka, Toshiko and Teumer, Alexander and van Vliet-Ostaptchouk, Jana V and Yengo, Loïc and Zhang, Weihua and Albrecht, Eva and Ärnlöv, Johan and Arscott, Gillian M and Bandinelli, Stefania and Barrett, Amy and Bellis, Claire and Bennett, Amanda J and Berne, Christian and Blüher, Matthias and Böhringer, Stefan and Bonnet, Fabrice and Böttcher, Yvonne and Bruinenberg, Marcel and Carba, Delia B and Caspersen, Ida H and Clarke, Robert and Daw, E. Warwick and Deelen, Joris and Deelman, Ewa and Delgado, Graciela and Doney, Alex S. F and Eklund, Niina and Erdos, Michael R and Estrada, Karol and Eury, Elodie and Frieich, Nele and Garcia, Melissa E and Gieaitis, Vilmantas and Gigante, Bruna and Go, Alan S and Golay, Alain and Grallert, Harald and Grammer, Tanja B and Gräßler, Jürgen and Grewal, Jagvir and Groves, Christopher J and Haller, Toomas and Hallmans, Goran and ... and PAGE Consortium and LifeLines Cohort Study and CARDIOGRAMplusC4D Consortium and MuTHER Consortium and ICBP and ADIPOGEN Consortium and CKDGen Consortium and GEFOS Consortium and Int Endogene Consortium and GENIE Consortium and MAGIC Investigators and ReproGen Consortium and GLGC and ADIPOGen Consortium and International Endogene Consortium and The PAGE Consortium and The International Endogene Consortium and The MAGIC Investigators and The ReproGen Consortium and The CKDGen Consortium and The ADIPOGen Consortium and The ICBP and The CARDIOGRAMplusC4D Consortium and The GENIE Consortium and The GLGC and The GEFOS Consortium and The MuTHER Consortium and The LifeLines Cohort Study and Högskolan Dalarna and Akademin Utbildning, hälsa och samhälle and Medicinsk vetenskap
Nature, ISSN 0028-0836, 2015, Volume 518, Issue 7538, pp. 187 - U378
Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our... 
HUMAN HEIGHT | ABDOMINAL ADIPOSITY | MULTIDISCIPLINARY SCIENCES | COMMON SNPS | SUSCEPTIBILITY LOCI | GLYCEMIC TRAITS | FALSE DISCOVERY | MESENCHYMAL STEM-CELLS | GENOME-WIDE ASSOCIATION | ADIPOGENIC DIFFERENTIATION | SEXUAL-DIMORPHISM | Body Mass Index | Genome-Wide Association Study | Age Factors | Neovascularization, Physiologic - genetics | Epigenesis, Genetic | Humans | Male | Continental Population Groups - genetics | Sex Characteristics | Obesity - genetics | Europe - ethnology | Genome, Human - genetics | Adipose Tissue - metabolism | Insulin - metabolism | Models, Biological | Adipocytes - metabolism | Insulin Resistance - genetics | Polymorphism, Single Nucleotide - genetics | Female | Body Fat Distribution | Transcription, Genetic - genetics | Adipogenesis - genetics | Waist-Hip Ratio | Quantitative Trait Loci - genetics | Adipose tissues | Quantitative trait loci | Genetic research | Genetic aspects | Research | Metabolism | Health aspects | Studies | Body mass index | Genealogy | Body fat | Insulin resistance | Genetics | Genomes | Abdomen | Meta-analysis | Life Sciences | Adipocytes/metabolism Adipogenesis/genetics Adipose Tissue/metabolism Age Factors Body Fat Distribution Body Mass Index Continental Population Groups/genetics Epigenesis, Genetic Europe/ethnology Female Genome, Human/genetics Genome-Wide Association Study Humans Insulin/metabolism Insulin Resistance/genetics Male Models, Biological Neovascularization, Physiologic/genetics Obesity/genetics Polymorphism, Single Nucleotide/genetics Quantitative Trait Loci/genetics Sex Characteristics Transcription, Genetic/genetics Waist-Hip Ratio | Clinical Medicine | Hälsa och välfärd | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Health and Welfare
Journal Article
The Journal of Sexual Medicine, ISSN 1743-6095, 05/2016, Volume 13, Issue 5, pp. S216 - S216
Journal Article
by Shvetsova, Ekaterina and Sofronova, Alina and Monajemi, Ramin and Gagalova, Kristina and Draisma, Harmen H. M and White, Stefan J and Santen, Gijs W. E and Chuva de Sousa Lopes, Susana M and Heijmans, Bastiaan T and van Meurs, Joyce and Jansen, Rick and Franke, Lude and Kiełbasa, Szymon M and den Dunnen, Johan T and ‘t Hoen, Peter A. C and Heijmans, Bastiaan T and ‘t Hoen, Peter A. C and van Meurs, Joyce and Boomsma, Dorret I and Pool, René and van Dongen, Jenny and Hottenga, Jouke J and van Greevenbroek, Marleen Mj and Stehouwer, Coen Da and van der Kallen, Carla Jh and Schalkwijk, Casper G and Wijmenga, Cisca and Zhernakova, Sasha and Tigchelaar, Ettje F and Slagboom, P Eline and Beekman, Marian and Deelen, Joris and van Heemst, Diana and Veldink, Jan H and van den Berg, Leonard H and van Duijn, Cornelia M and Hofman, Bert A and Uitterlinden, André G and Jhamai, P Mila and Verbiest, Michael and Suchiman, H Eka D and Verkerk, Marijn and van der Breggen, Ruud and van Rooij, Jeroen and Lakenberg, Nico and Mei, Hailiang and Bot, Jan and Zhernakova, Dasha V and van ’t Hof, Peter and Deelen, Patrick and Nooren, Irene and Moed, Matthijs and Vermaat, Martijn and Luijk, René and Jan Bonder, Marc and van Iterson, Maarten and van Dijk, Freerk and van Galen, Michiel and Arindrarto, Wibowo and Kiełbasa, Szymon M and Swertz, Morris A and van Zwet, Erik W and Isaacs, Aaron and Jansen, Rick and Franke, Lude and Francioli, Lc and Menelaou, A and Pulit, Sl and van Dijk, F and Palamara, Pf and Elbers, Cc and Neerincx, Pb and Ye, K and Guryev, V and Kloosterman, Wp and Deelen, P and Abdellaoui, A and van Leeuwen, Em and van Oven, M and Vermaat, M and Li, M and Laros, Jf and Karssen, Lc and Kanterakis, A and Amin, N and Hottenga, Jj and Lameijer, Ew and Kattenberg, M and Dijkstra, M and Byelas, H and van Setten, J and van Schaik, Bd and Bot, J and Nijman, Ij and Renkens, I and Marschall, T and Schönhuth, A and Hehir-Kwa, Jy and Handsaker, Re and Polak, P and ... and GoNL Consortium and BIOS Consortium and GoNL consortium and BIOS consortium
European Journal of Human Genetics, ISSN 1018-4813, 03/2019, Volume 27, Issue 3, pp. 455 - 465
X-inactivation is a well-established dosage compensation mechanism ensuring that X-chromosomal genes are expressed at comparable levels in males and females.... 
VARIABILITY | TRANSLOCATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DMD LOCUS | GENETICS & HEREDITY | ADRENOLEUKODYSTROPHY | CONSEQUENCES | PATTERNS | DUCHENNE MUSCULAR-DYSTROPHY | CHROMOSOME-INACTIVATION | EXPRESSION | CARRIERS | Dosage compensation | Alleles | Population | Genomes | Negative selection | Females | Ribonucleic acid--RNA | Chromosomes | Embryos | Blood | Hemopoiesis
Journal Article