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Journal of Biological Chemistry, ISSN 0021-9258, 09/2008, Volume 283, Issue 36, pp. 24770 - 24780
Accumulation of indigestible lipofuscin and decreased mitochondrial energy production are characteristic age-related changes of post-mitotic retinal pigment... 
LIPOFUSCIN FLUOROPHORE | RAT | DYSTROPHY | DNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | MACULAR DEGENERATION | COMPONENT | RPE CELLS | N-RETINYLIDENE ETHANOLAMINE | BINDING | PHOTORECEPTORS | Retinoids - metabolism | Epithelial Cells - metabolism | Lipofuscin - pharmacology | Antioxidants - metabolism | Humans | Lysosomes - genetics | Rats, Long-Evans | Adenosine Triphosphate - genetics | Phagocytosis - genetics | Membrane Potential, Mitochondrial - drug effects | Mitosis - genetics | Oxidative Phosphorylation - drug effects | DNA, Mitochondrial - genetics | Lysosomes - metabolism | Aging - genetics | Cell Death - genetics | Mitochondria - genetics | Adenosine Triphosphate - metabolism | Membrane Potential, Mitochondrial - genetics | Pyruvic Acid - metabolism | Lysosomes - pathology | Cell Death - drug effects | Cell Line | Phagocytosis - drug effects | DNA, Mitochondrial - metabolism | Rats | Epithelial Cells - pathology | Mitochondria - metabolism | Antioxidants - pharmacology | Mitochondria - pathology | Aging - pathology | Pigment Epithelium of Eye - metabolism | Macular Degeneration - metabolism | Point Mutation | Pyridinium Compounds - pharmacology | Animals | Mitosis - drug effects | Macular Degeneration - genetics | Glucose - metabolism | Pigment Epithelium of Eye - pathology | Pyridinium Compounds - metabolism | Lipofuscin - metabolism | Retinoids - pharmacology | Aging - metabolism | Macular Degeneration - pathology | Index Medicus | Molecular Basis of Cell and Developmental Biology
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 11/2013, Volume 288, Issue 45, pp. 32639 - 32639
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2003, Volume 278, Issue 20, p. 18207
The autofluorescent pigments that accumulate in retinal pigment epithelial cells with aging and in some retinal disorders have been implicated in the etiology... 
Journal Article
Organic Letters, ISSN 1523-7060, 06/2005, Volume 7, Issue 13, pp. 2799 - 2801
Bridged bicyclic dienones underwent silyl-directed Nazarov cyclization with generally very high diastereoselectivity. In most cases, a strong preference for... 
CHEMISTRY, ORGANIC | ROUTE | EFFICIENT CATALYSIS | NORBORNENES | CYCLOPENTANNELATION | Bridged Bicyclo Compounds - chemical synthesis | Bridged Bicyclo Compounds - chemistry | Cyclization | Ketones - chemical synthesis | Stereoisomerism | Ketones - chemistry | Indicators and Reagents | Catalysis | Cyclopentanes - chemical synthesis
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 04/2004, Volume 126, Issue 14, pp. 4646 - 4652
The photochemistry of the retinoid analogue A1E shows an oxygen and solvent dependence. Irradiation of A1E with visible light (λirr = 425 nm) in methanol... 
Cyclization | Oxidation-Reduction | Photolysis | Retinoids - chemistry | Nuclear Magnetic Resonance, Biomolecular | Pyridinium Compounds - chemistry | Spectrum Analysis | Photochemistry | Pyridinium compounds | Research
Journal Article
Advances in Experimental Medicine and Biology, ISSN 0065-2598, 2005, Volume 572, pp. 69 - 74
Journal Article
2006, Advances in Experimental Medicine and Biology, ISBN 0387284648, Volume 572
For many years, blue light damage associated with retinal pigment epithelial (RPE) cell lipofuscin (LF) has been implicated in the cause of age-related macular... 
Medicine & Public Health | Life Sciences, general | Quality of Life Research | Ophthalmology | Anatomy | Epidemiology
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