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Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 06/2011, Volume 29, Issue 18, pp. 2493 - 2498
Journal Article
IEEE/ASME Transactions on Mechatronics, ISSN 1083-4435, 06/2015, Volume 20, Issue 3, pp. 1384 - 1394
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2013, Volume 8, Issue 11, p. e80070
Purpose: Aberrant PI3K/AKT/mTOR signaling has been linked to oncogenesis and therapy resistance in various malignancies including leukemias. In Philadelphia... 
MAMMALIAN TARGET | RAPAMYCIN | PIK3CA GENE | MULTIDISCIPLINARY SCIENCES | IN-VIVO | T-CELL LEUKEMIA | KINASE INHIBITORS | ACUTE MYELOID-LEUKEMIA | MTOR COMPLEX | CANCER-THERAPY | MOLECULAR-MECHANISMS | TOR Serine-Threonine Kinases - metabolism | Humans | Gene Expression Regulation, Neoplastic | Multiprotein Complexes - genetics | Phosphatidylinositol 3-Kinases - metabolism | Mechanistic Target of Rapamycin Complex 2 | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Proto-Oncogene Proteins c-akt - genetics | Quinolines - pharmacology | Mechanistic Target of Rapamycin Complex 1 | Multiprotein Complexes - antagonists & inhibitors | TOR Serine-Threonine Kinases - antagonists & inhibitors | Multiprotein Complexes - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | TOR Serine-Threonine Kinases - genetics | Antineoplastic Agents - pharmacology | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Proto-Oncogene Proteins c-akt - metabolism | Everolimus | Lymphocytes - metabolism | Sirolimus - analogs & derivatives | Morpholines - pharmacology | Imidazoles - pharmacology | Pyrimidines - pharmacology | Sirolimus - pharmacology | Drug Synergism | Phosphatidylinositol 3-Kinases - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Fusion Proteins, bcr-abl - genetics | Lymphocytes - pathology | Signal Transduction - drug effects | Aminopyridines - pharmacology | Lymphocytes - drug effects | Fusion Proteins, bcr-abl - antagonists & inhibitors | Primary Cell Culture | Fusion Proteins, bcr-abl - metabolism | Naphthyridines - pharmacology | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Tyrosine | Genetic aspects | Comparative analysis | Health aspects | Long-term care of the sick | Cancer | TOR protein | BCR protein | Phosphorylation | Pathogenesis | Leukemia | Clinical trials | Oncology | AKT protein | Kinases | Anticancer properties | Cell growth | Allosteric properties | Precursors | Cell cycle | Tumorigenesis | Inhibition | Fusion protein | Growth factors | Protein-tyrosine kinase | Medical research | Cell survival | Acute lymphatic leukemia | Hematology | Therapeutic applications | Abl protein | Lymphatic leukemia | Patients | 1-Phosphatidylinositol 3-kinase | Philadelphia chromosome | Medicine | Signaling | Inhibitors | Experimental design | Medical prognosis | Mutation | ATP | Apoptosis
Journal Article
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program, 2009, pp. 371 - 381
The tyrosine kinase inhibitor (TKI) imatinib has become an integral part of front-line therapy for Ph(+) ALL, with remission rates exceeding 90% irrespective... 
Piperazines - administration & dosage | Precursor Cell Lymphoblastic Leukemia-Lymphoma - surgery | Humans | Salvage Therapy | Central Nervous System - pathology | Drug Resistance, Neoplasm | Neoplasm Proteins - antagonists & inhibitors | Thiazoles - administration & dosage | Secondary Prevention | Thiazoles - therapeutic use | Neoplasm, Residual | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Antibodies, Bispecific - administration & dosage | Adult | Transplantation Conditioning - methods | Neoplasm Proteins - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Child | Philadelphia Chromosome | Dasatinib | Pyrimidines - administration & dosage | Hematopoietic Stem Cell Transplantation | Combined Modality Therapy | Piperazines - therapeutic use | Imatinib Mesylate | Antibodies, Bispecific - therapeutic use | Protein Kinase Inhibitors - administration & dosage | Fusion Proteins, bcr-abl - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Leukemic Infiltration - prevention & control | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | Adolescent | Fusion Proteins, bcr-abl - antagonists & inhibitors | Leukemic Infiltration - drug therapy | Precursor Cell Lymphoblastic Leukemia-Lymphoma - enzymology | Benzamides | Mutation | Adrenal Cortex Hormones - administration & dosage
Journal Article
Chemical Engineering and Processing - Process Intensification, ISSN 0255-2701, 03/2018, Volume 125, pp. 325 - 333
For the intensification of a dehydrogenation reaction, a membrane reactor concept with palladium foils was tested. A planar membrane module with... 
Microstructured reactor | Film effectiveness factor | Optimization of membrane area | Concentration polarization | Palladium foil | METHANOL | ENERGY & FUELS | SIMULATION | ENGINEERING, CHEMICAL | PURE HYDROGEN | TRANSPORT | MODULE | TEMPERATURE | HYDROGEN PERMEATION | CONCENTRATION-POLARIZATION | HEAT-STORAGE | PALLADIUM MEMBRANE
Journal Article
International Journal of Cancer, ISSN 0020-7136, 10/2016, Volume 139, Issue 8, pp. 1799 - 1809
Journal Article
Journal Article
by Nauth, Aaron and Creek, Aaron T and Zellar, Abby and Lawendy, Abdel-Rahman and Dowrick, Adam and Gupta, Ajay and Dadi, Akhil and van Kampen, Albert and Yee, Albert and de Vries, Mark R and de Vries, Jean Paul P.M and de Vries, Alexander C and de Mol van Otterloo, Alexander and Garibaldi, Alisha and Liew, Susan and Liew, Allen and McIntyre, Allison W and Prasad, Amal Shankar and Romero, Amanda W and Rangan, Amar and Oatt, Amber and Sanghavi, Amir and Foley, Amy L and Karlsten, Anders and Dolenc, Andrea and Bucknill, Andrew and Chia, Andrew and Evans, Andrew and Evans, Simone and Gong, Andrew and Schmidt, G. Ben and Schmidt, Andrew H and Marcantonio, Andrew J and Jennings, Andrew and Ward, Angela and Khanna, Angshuman and Rai, Anil and Rai, B. Sachidananda and Rai, Kamal and Smits, Anke B and Horan, Annamarie D and Brekke, Anne Christine and Flynn, Annette and Duraikannan, Aravin and Stødle, Are and van Vugt, Arie B and Luther, Arlene and Zurcher, Arthur W and Jain, Arvind and Jain, Neeraj and Amundsen, Asgeir and Moaveni, Ash and Carr, Ashley and Sharma, Gaurav and Sharma, Ateet and Hill, Austin D and Trommer, Axel and Hileman, Barbara and Schreurs, Bart and Verhoeven, Bart and Barden, Benjamin B and Flatøy, Bernhard and Cleffken, Berry I and Bøe, Berthe and Perey, Bertrand and Hanusch, Birgit C and Weening, Brad and Fioole, Bram and Rijbroek, Bram and Crist, Brett D and Halliday, Brett and Peterson, Brett and Mullis, Brian and Richardson, C. Glen and Richardson, Martin and Clark, Callum and Sagebien, Carlos A and van der Pol, Carmen C and Bowler, Carol and Humphrey, Catherine A and Coady, Catherine and Koppert, Cees L and Coles, Chad and Tannoury, Chadi and DePaolo, Charles J and Gayton, Chris and Herriott, Chris and Reeves, Christina and Tieszer, Christina and Dobb, Christine and Anderson, Linda K and Anderson, Christopher G and Anderson, Sarah A and Sage, Claire and Cuento, Claudine and Jones, Vicki and Jones, Clifford B and Bosman, Coks H.R and Linehan, Colleen and van der Hart, Cor P and ... and Fixation using Alternative Implants for the Treatment of Hip fractures (FAITH) Investigators
The Lancet, ISSN 0140-6736, 04/2017, Volume 389, Issue 10078, pp. 1519 - 1527
Journal Article
Immunity, ISSN 1074-7613, 05/2019, Volume 50, Issue 5, pp. 1232 - 1248.e14
Journal Article