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Journal of Pharmaceutical Sciences, ISSN 0022-3549, 09/2016, Volume 105, Issue 9, pp. 2723 - 2734
In recent years, there has been a significant increase in use of physiologically based pharmacokinetic models in drug development and regulatory applications.... 
pharmacokinetics | particle size | food effects | absorption | physiologically based pharmacokinetic modeling | oral absorption | Predictive Value of Tests | Drug Industry | Humans | Biopharmaceutics | Intestinal Absorption | Particle Size | Animals | Models, Biological | Computer Simulation | Dogs | Drug Compounding | Software | Pharmacokinetics | Therapeutic Equivalency
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 04/2016, Volume 105, Issue 4, pp. 1398 - 1404
NVS123 is a poorly water-soluble protease 56 inhibitor in clinical development. Data from in vitro hepatocyte studies suggested that NVS123 is mainly... 
Journal Article
Current Pharmacology Reports, ISSN 2198-641X, 12/2018, Volume 4, Issue 6, pp. 491 - 501
This article provides a brief overview of the development of pediatric physiologically based pharmacokinetic (PPBPK) models, the challenges of uncertain... 
Biomedicine, general | Simulations | Biomedicine | Physiologically based pharmacokinetic modeling | Drug-metabolizing enzymes | Elimination | Cancer Research | Molecular Medicine | Pharmacology/Toxicology | Preclinical pharmacokinetics | Clinical pharmacokinetics
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 01/2019, Volume 108, Issue 1, pp. 592 - 602
Journal Article
Biopharmaceutics & Drug Disposition, ISSN 0142-2782, 03/2018, Volume 39, Issue 3, pp. 152 - 163
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 06/2019, Volume 108, Issue 6, pp. 2191 - 2198
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 01/2019, Volume 108, Issue 1, pp. 87 - 101
Journal Article
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 02/2018, Volume 536, Issue 2, pp. 530 - 535
A small amount of food is commonly used to aid administration of medicines to children to improve palatability and/or swallowability. However the impact of... 
Fed-effect | Paediatric | Biopharmaceutics | DRUG | PHARMACOKINETICS | METABOLISM | PHARMACOLOGY & PHARMACY | MECHANISMS | CHILDREN | Animals | Food-Drug Interactions | Humans | Pharmaceutical Preparations - administration & dosage | Child | Food
Journal Article