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Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, p. e85715
We investigated early cellular responses induced by infection with Leishmania major in macrophages from resistant C57/BL6 mice. Infection increased production... 
SIGNAL-TRANSDUCTION | FAS LIGAND | TUMOR-NECROSIS-FACTOR | INDUCED APOPTOSIS | NITRIC-OXIDE SYNTHASE | MULTIDISCIPLINARY SCIENCES | MAP KINASES | MICE | TNF-ALPHA | EXPRESSION | T-LYMPHOCYTES | Parasites - physiology | Fas Ligand Protein - metabolism | Reactive Oxygen Species - metabolism | Antioxidants - metabolism | JNK Mitogen-Activated Protein Kinases - metabolism | Leishmania major - physiology | Macrophages - parasitology | Parasites - drug effects | Leishmania major - growth & development | Stress, Physiological - drug effects | Cell Death - drug effects | Parasites - growth & development | Chemokines - biosynthesis | Macrophages - pathology | Leishmania major - drug effects | Mice, Inbred C57BL | Leishmaniasis, Cutaneous - pathology | Macrophages - enzymology | Up-Regulation - drug effects | Animals | MAP Kinase Signaling System - drug effects | Leishmaniasis, Cutaneous - parasitology | Macrophages - drug effects | Mice | Mice, Inbred BALB C | Protein Kinase Inhibitors - pharmacology | Infection | Antioxidants | Medical research | Tumor necrosis factor | Acetylcysteine | Medicine, Experimental | Macrophages | Health aspects | Oxidative stress | Reactive oxygen species | Transcription factors | Infections | Activation | Interleukin 1 receptors | Parasites | Kinases | Tissue inhibitor of metalloproteinase 1 | Deferoxamine | Interleukin 6 | Proteins | Signal transduction | Cell activation | Granulocyte colony-stimulating factor | Parasitic diseases | Tumor necrosis factor-TNF | Stress response | Stresses | Cell survival | Cytokines | Secretion | Interleukin 1 receptor antagonist | Neutrophils | c-Jun protein | Inflammation | Biophysics | Tumor necrosis factor-α | Gene expression | Inhibitors | FasL protein | Ligands | Replication | Macrophage inflammatory protein | Chemokines | Monocyte chemoattractant protein 1 | Cellular stress response | Peritoneum | Apoptosis
Journal Article
Journal Article
International Journal for Parasitology: Drugs and Drug Resistance, ISSN 2211-3207, 12/2018, Volume 8, Issue 3, pp. 475 - 487
Previous work from our group showed that tamoxifen, an oral drug that has been in use for the treatment of breast cancer for over 40 years, is active both and... 
Sphingolipids | IPC synthase | Tamoxifen | Inositolphosphorylceramide | Leishmania amazonensis | Phosphatidylinositols | BRAZILIENSIS | INOSITOL PHOSPHORYLCERAMIDE SYNTHASE | SPHINGOLIPID SYNTHESIS | PROTEIN-KINASE | CERAMIDE | MASS-SPECTROMETRY | THERAPY | METABOLISM | PHARMACOLOGY & PHARMACY | TRANSPORT FUNCTION | MYO-INOSITOL-1-PHOSPHATE SYNTHASE | PARASITOLOGY
Journal Article
Enzyme Research, ISSN 2090-0406, 2011, Volume 2011, Issue 1, pp. 648159 - 13
The protozoan parasite Trypanosoma cruzi is the causative agent of human Chagas disease, for which there currently is no cure. The life cycle of T. cruzi is... 
Chemotherapy | Synthesis | Physiological aspects | Lipids | Sphingolipids | Chagas' disease | Research | Drug therapy | Health aspects | Cancer
Journal Article
Journal Article
Current Organic Chemistry, ISSN 1385-2728, 07/2008, Volume 12, Issue 11, pp. 926 - 939
This review highlights the chemical structures of complex glycoconjugates from protozoan and helminth parasites, etiologic agents of major world-wide... 
FORM TRYPANOSOMA-BRUCEI | LEISHMANIA-MAJOR | DE-NOVO SYNTHESIS | SCHISTOSOMA-MANSONI EGG | N-GLYCANS | LEWIS-X | EXCRETORY-SECRETORY PRODUCT | TRICHINELLA-SPIRALIS | CHEMISTRY, ORGANIC | HEPATIC GRANULOMA-FORMATION | GPI-ANCHORED PROTEINS
Journal Article
Journal of Bioenergetics and Biomembranes, ISSN 0145-479X, 04/2017, Volume 49, Issue 2, p. 183
Trypanosoma brucei is an extracellular protozoan parasite that causes human African trypanosomiasis or "sleeping sickness". During the different phases of its... 
Journal Article
Journal of Bioenergetics and Biomembranes, ISSN 0145-479X, 04/2017, Volume 49, Issue 2, pp. 183 - 194
Trypanosoma brucei is an extracellular protozoan parasite that causes human African trypanosomiasis or "sleeping sickness". During the different phases of its... 
Journal Article
Journal of Bioenergetics and Biomembranes, ISSN 0145-479X, 04/2017, Volume 49, Issue 2, p. 183
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1007/s10863-017-9695-y... 
Phosphates | Inositol | Analysis | Enzyme kinetics | Gene expression
Journal Article
Journal Article
Journal Article