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Journal of Clinical Oncology, ISSN 0732-183X, 05/2016, Volume 34, Issue 15_suppl, pp. e20623 - e20623
Journal Article
Nature Genetics, ISSN 1061-4036, 01/2017, Volume 49, Issue 1, pp. 65 - 74
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2018, Volume 36, Issue 15_suppl, pp. e21156 - e21156
Journal Article
Lancet Oncology, ISSN 1470-2045, 2009, Volume 10, Issue 8, pp. 772 - 784
Journal Article
Lancet Oncology, ISSN 1470-2045, 10/2017, Volume 18, Issue 10, pp. 1307 - 1316
Background: BRAF(V600E) mutation occurs in 1-2% of lung adenocarcinomas and acts as an oncogenic driver. Dabrafenib, alone or combined with trametinib, has... 
SURVIVAL | HARBORING BRAF MUTATIONS | 1ST-LINE TREATMENT | MULTICENTER | MELANOMA | PEMBROLIZUMAB | ONCOLOGY | CRIZOTINIB | MULTICOHORT | CHEMOTHERAPY | EGFR
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2019, Volume 37, Issue 15_suppl, pp. e20544 - e20544
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2018, Volume 36, Issue 15_suppl, pp. e21026 - e21026
Journal Article
BMC Cancer, ISSN 1471-2407, 02/2016, Volume 16, Issue 1, p. 71
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2012, Volume 109, Issue 8, pp. 2802 - 2807
We use an integrated approach to understand breast cancer heterogeneity by modeling mRNA, copy number alterations, micro-RNAs, and methylation in a pathway... 
Datasets | T lymphocytes | Messenger RNA | BREAST CANCER SPECIAL FEATURE | Noninfiltrating intraductal carcinoma | Breast cancer | Mast cells | Macrophages | Signatures | Tumors | Cancer | Integrated molecular data | Perturbated pathway | Functional genomics | Omics | IMMUNE-RESPONSE | perturbated pathway | CANCER CELLS | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | functional genomics | FOXM1 | PORTRAITS | integrated molecular data | omics | INFLAMMATION | INTERFERONS | T-CELLS | PROGRESSION | Prognosis | Genomics | Humans | Gene Expression Regulation, Neoplastic | Databases, Genetic | Carcinoma, Intraductal, Noninfiltrating - genetics | Gene Expression Profiling | Th2 Cells - immunology | Th1 Cells - immunology | Interleukins - metabolism | Carcinoma, Intraductal, Noninfiltrating - immunology | Female | Breast Neoplasms - classification | Reproducibility of Results | Neoplasm Invasiveness | Mammography | Signal Transduction - genetics | Breast Neoplasms - blood supply | Algorithms | Breast Neoplasms - genetics | Carcinoma, Intraductal, Noninfiltrating - pathology | Breast Neoplasms - pathology | Survival Analysis | Lymphocyte Count | Carcinoma, Intraductal, Noninfiltrating - classification | Lymphocytes, Tumor-Infiltrating - immunology | Interleukins | RNA | Physiological aspects | Carcinoma, Ductal | Development and progression | Genetic aspects | Research | Health aspects | Biological Sciences | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
Lancet Oncology, ISSN 1470-2045, 10/2017, Volume 18, Issue 10, p. 1307
BRAF.sup.V600E mutation occurs in 1--2% of lung adenocarcinomas and acts as an oncogenic driver. Dabrafenib, alone or combined with trametinib, has shown... 
Complications and side effects | Medical research | Care and treatment | Analysis | Medicine, Experimental | Metastasis | Lung cancer, Non-small cell
Journal Article
by Seidel, Danila and Zander, Thomas and Heukamp, Lukas C and Peifer, Martin and Bos, Marc and Fernandez-Cuesta, Lynnette and Leenders, Frauke and Lu, Xin and Ansen, Sascha and Gardizi, Masyar and Nguyen, Chau and Berg, Johannes and Russell, Prudence and Wainer, Zoe and Schildhaus, Hans-Ulrich and Rogers, Toni-Maree and Solomon, Benjamin and Pao, William and Carter, Scott L and Getz, Gad and Hayes, D. Neil and Wilkerson, Matthew D and Thunnissen, Erik and Travis, William D and Perner, Sven and Wright, Gavin and Brambilla, Elisabeth and Buettner, Reinhard and Wolf, Juergen and Thomas, Roman and Gabler, Franziska and Wilkening, Ines and Mueller, Christian and Dahmen, Ilona and Menon, Roopika and Koenig, Katharina and Albus, Kerstin and Merkelbach-Bruse, Sabine and Fassunke, Jana and Schmitz, Katja and Kuenstlinger, Helen and Kleine, Michaela and Binot, Elke and Querings, Silvia and Altmueller, Janine and Boessmann, Ingelore and Nuemberg, Peter and Schneider, Peter and Bogus, Magdalena and Soltermann, Alex and Moch, Holger and Brustugun, Odd Terje and Solberg, Steinar and Lund-Iversen, Marius and Helland, Aslaug and Muley, Thomas and Hoffmann, Hans and Schnabel, Philipp A and Chen, Yuan and Groen, Harry and Timens, Wim and Sietsma, Hannie and Clement, Joachim H and Weder, Walter and Saenger, Joerg and Stoelben, Erich and Ludwig, Corinna and Engel-Riedel, Walburga and Smit, Egbert and Heideman, Danille A. M and Snijders, Peter J. F and Nogova, Lucia and Sos, Martin L and Mattonet, Christian and Toepelt, Karin and Scheffler, Matthias and Goekkurt, Eray and Kappes, Rainer and Krueger, Stefan and Kambartel, Kato and Behringer, Dirk and Schulte, Wolfgang and Galetke, Wolfgang and Randerath, Winfried and Heldwein, Matthias and Schlesinger, Aneas and Serke, Monika and Hekmat, Khosro and Frank, Konrad F and Schnell, Roland and Reiser, Marcel and Huenerlituerkoglu, Ali-Nuri and Schmitz, Stephan and Meffert, Lisa and Ko, Yon-Dschun and Litt-Lampe, Markus and Gerigk, Ulrich and Fricke, Rainer and Besse, Benjamin and Brambilla, Christian and ... and CLCGP and NGM and Clinical Lung Cancer Genome Project (CLCGP) and Network Genomic Medicine (NGM) and The Clinical Lung Cancer Genome Project (CLCGP) and Network Genomic Medicine (NGM)
Science Translational Medicine, ISSN 1946-6234, 10/2013, Volume 5, Issue 209, pp. 209ra153 - 209ra153
We characterized genome alterations in 1255 clinically annotated lung tumors of all histological subgroups to identify genetically defined and clinically... 
MEDICINE, RESEARCH & EXPERIMENTAL | GEFITINIB | FUSION | GENE | NRF2 | ADENOCARCINOMA | OPEN-LABEL | SQUAMOUS-CELL CARCINOMAS | CANCER | ACTIVATING MUTATIONS | DRIVER MUTATIONS | CELL BIOLOGY | Lung Neoplasms - genetics | Lung Neoplasms - classification | Automation | Genomics | Humans | Lung Neoplasms - pathology | Lung Neoplasms - diagnosis | Genome, Human - genetics
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 4, p. e18064
Journal Article
Cancer discovery, ISSN 2159-8274, 06/2011, Volume 1, Issue 1, pp. 78 - 89
Journal Article