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ACS Medicinal Chemistry Letters, ISSN 1948-5875, 03/2018, Volume 9, Issue 3, pp. 238 - 243
Ubiquitin specific protease 7 (USP7, HAUSP) has become an attractive target in drug discovery due to the role it plays in modulating Mdm2 levels and... 
proteasome | USP7 | ubiquitination | Mdm2 | HAUSP | deubiquitinase | ubiquitin | p53 | CHEMISTRY, MEDICINAL | CANCER | DISCOVERY | POTENT | SMALL-MOLECULE INHIBITORS | USP7/HAUSP
Journal Article
Chemistry - A European Journal, ISSN 0947-6539, 05/2013, Volume 19, Issue 21, pp. 6509 - 6509
Journal Article
Chemistry, ISSN 0947-6539, 05/2013, Volume 19, Issue 21, p. 6509
Journal Article
by Ghinda, Diana and Chen, Suzan and Bedaiwy, Mahmoud and Jabri, Hussam and Alshardan, Mohammad and Taccone, Michael S and Lai, Carolyn and Rabski, Jessica and Tsai, Eve and Dedek, Annemarie and Xu, Jian and Tsai, Eve and Lombroso, Paul and Hildebrand, Mike and Mothe, Andrea and Tator, Charles H and Siladi, Andrew and Nally, Jaqueline and Stirling, David and Keller, Anastasia and Buckley, Christian and Shum-Siu, Alice and Magnuson, David and Rosenbaum, Benjamin P and Kelly, Michael L and Ahuja, Christopher and Ahuja, Christopher and Nori, Satoshi and Khazaei, Mohamad and Ahlfors, Jan-Eric and Liu, Yang and Wang, Jian and Fuehrmann, Tobias and Pakulska, Malgosia and Hettiaratchi, Marian H and Poon, Peter and Shoichet, Molly S and Fehlings, Michael G and Fehlings, Michael G and Fehlings, Michael G and Hazrati, Lili-Naz and Cherian, Leela and Nilewski, Lizanne and Tour, James M and Kent, Thomas A and Robertson, Claudia S and Wilde, Elisabeth and Newsome, Mary and Scheibel, Randall and Troyanskaya, Maya and Velez, Carmen and Wade, Benjamin and Drennon, Ann Marie and York, Gerald and Bigler, Erin and Abildskov, Tracy and Taylor, Brian and Jaramillo, Carlos and Eapen, Blessen and Belanger, Heather and Morey, Rajendra and Haswell, Courtney and Levin, Harvey and Hinds, Sidney and Walker, William and Walker, William and Kochunov, Peter and Jahanshad, Neda and Thompson, Paul and Tate, David and Statz, Jonathan and Goodrich, Jessica and Goforth, Cdr Carl and Tschiffely, Anna E and Arena, John D and Smith, Douglas H and Wolf, John A and Johnson, Victoria E and Rhodes, James and Friess, Stuart and Lee, Taylor and Lycke, Roy J and Jang, Ikbeom and Vike, Nicole L and Nauman, Eric A and Talavage, Thomas M and Rispoli, Joseph V and Alonso-Escalante, Jose and Fulton, William and Sodhi, Chhinder and Hackam, David J and Nasr, Isam W and Hubbard, W B and Joseph, Binoy and Spry, Malinda L and Vekaria, Hemendra J and Saatman, Kathryn and Sullivan, Patrick G and Sullivan, Patrick G and Vascak, Michal and ...
Journal of Neurotrauma, ISSN 0897-7151, 08/2018, Volume 35, Issue 16, pp. A-1 - A-285
[...]the vast majority of basic science pain research ends at target identification and validation in rodent models of chronic pain without confirmation in... 
Abstracts | Neurosciences | Keywords | Traumatic brain injury | Cytokines | Central nervous system | Inflammation | Gene expression | Trauma | Studies | Brain research | Hospitals | Pain | Rodents | Stem cells | DNA methylation | Biomarkers | Spinal cord injuries | Growth factors | Research centers | Proteins
Journal Article
Chemical Communications, ISSN 1359-7345, 01/2011, Volume 47, Issue 46, pp. 12459 - 12461
Electrophilic direct borylation is facilitated, and arene substrate scope enhanced, by using electrophiles derived from inexpensive reagents; specifically an... 
Boron | Amines
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 02/2018, Volume 14, Issue 2, pp. 118 - 125
Given the importance of ubiquitin-specific protease 7 (USP7) in oncogenic pathways, identification of USP7 inhibitors has attracted considerable interest.... 
INACTIVATION | DUBS | STABILIZATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | HAUSP | ACTIVATES P53 | PROTEASES | Ubiquitin | Cell culture | MDM2 protein | Ubiquitin-specific proteinase | Antagonists | Tumor cell lines | Optimization | Allosteric properties | Inhibitors | Cell lines | Binding sites | Crystal structure | Cancer
Journal Article
ISSN 1359-7345, 11/2011, Volume 47, Issue 46, pp. 12459 - 12461
Electrophilic direct borylation is facilitated, and arene substrate scope enhanced, by using electrophiles derived from inexpensive reagents; specifically an... 
Journal Article
Chemical Communications, ISSN 1359-7345, 12/2011, Volume 47, Issue 46, pp. 12459 - 12461
Electrophilic direct borylation is facilitated, and arene substrate scope enhanced, by using electrophiles derived from inexpensive reagents; specifically an... 
POLYMERS | SOLAR-CELLS | DYES | COMPLEXES | ADDUCTS | AROMATIC BORYLATION | BORENIUM | BORANE | CHEMISTRY, MULTIDISCIPLINARY | H ACTIVATION | CATIONS
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 07/2009, Volume 50, Issue 26, p. 3224
Dialdehydes undergo sequenced SmI.sub.2-mediated cyclization cascades generating four contiguous stereocenters with high diastereocontrol. 
Samarium
Journal Article
Journal of Cardiovascular Electrophysiology, ISSN 1045-3873, 07/2019, Volume 30, Issue 7, pp. 1102 - 1107
Several Boston Scientific pacemaker models have a known issue with intermittent oversensing of the minute ventilation sensor when paired with non‐Boston... 
header | impedance | safety switch | lead fracture | minute ventilation | CARDIAC & CARDIOVASCULAR SYSTEMS | Incompatibility | Surgical implants | Pacemakers | Ventilation | Hybrid systems | Safety | Impedance | Stents | Switching | Catheters | High impedance
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2009, Volume 50, Issue 26, pp. 3224 - 3226
Dialdehydes undergo sequenced SmI -mediated cyclization cascades generating four contiguous stereocenters with high diastereocontrol. Dialdehydes undergo... 
Cyclization | Samarium | Radical | Cascade
Journal Article
Tetrahedron, ISSN 0040-4020, 2009, Volume 65, Issue 52, pp. 10816 - 10829
Dialdehydes undergo ‘radical then aldol’ cyclization cascades upon treatment with SmI , generating four contiguous stereocenters with high diastereocontrol.... 
Cyclization | Samarium | Radical | Cascade
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 11/2009, Volume 48, Issue 49, pp. 9315 - 9317
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 11/2007, Volume 46, Issue 45, pp. 8656 - 8658
From dipole to diazole! A direct and regioselective route to functionalized pyrazole boronic esters is developed that employs the cycloaddition of... 
regioselectivity | cycloaddition | heterocycles | boronic esters | Boronic esters | Heterocycles | Cycloaddition | Regioselectivity | DIELS-ALDER | FACILE SYNTHETIC ROUTE | BUILDING-BLOCKS | MEDIATED 2+2+2 CYCLOADDITION | CHEMISTRY, MULTIDISCIPLINARY | ARYLBORONIC ACIDS | ALKENES | CHEMISTRY | ARYL | CYCLOTRIMERIZATION | DERIVATIVES | Esters | Utilities | Joining | Dipoles | Pyrazole
Journal Article
Tetrahedron, ISSN 0040-4020, 12/2009, Volume 65, Issue 52, pp. 10816 - 10829
Dialdehydes undergo 'radical then aldol' cyclization cascades upon treatment with SmI , generating four contiguous stereocenters with high diastereocontrol.... 
Samarium | Cyclization | Radical | Cascade | UNSATURATED ALDEHYDES | IODIDE | COSOLVENT | CHEMISTRY, ORGANIC | FUNCTIONALIZED CYCLOBUTANOLS | SKELETON | REDUCTIONS | ALCOHOLS | STEREOSELECTIVE APPROACH | SAMARIUM(II)-MEDIATED 4-EXO-TRIG CYCLIZATION | PESTALOTIOPSIN-A
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 06/2005, Volume 44, Issue 25, pp. 3889 - 3892
Journal Article
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