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Journal of Dermatological Science, ISSN 0923-1811, 2014, Volume 75, Issue 2, pp. 109 - 120
Highlights • Strongly diminished pyrophosphate levels leading to intensified calcification of ECM in PXE cells. • We demonstrated a dysfunction of... 
Dermatology | Ectonucleotide pyrophosphatase 1 | Bisphosphonate | Tissue nonspecific alkaline phosphate | Pyrophosphate | ABCC6 | Calcification | Pseudoxanthoma elasticum | VASCULAR CALCIFICATION | DERMATOLOGY | BISPHOSPHONATES | INORGANIC PYROPHOSPHATE | MOUSE MODEL | ECTOPIC MINERALIZATION | GENERALIZED ARTERIAL CALCIFICATION | MUTATIONS | BONE | GLA PROTEIN | FETUIN-A | Calcinosis - genetics | Osteopontin - genetics | Diphosphates - metabolism | Humans | Transforming Growth Factor beta1 - metabolism | Alkaline Phosphatase - metabolism | Pyrophosphatases - genetics | Osteopontin - metabolism | RNA, Messenger - metabolism | Case-Control Studies | Elastic Tissue - metabolism | Time Factors | Multidrug Resistance-Associated Proteins - genetics | Calcinosis - metabolism | Fibroblasts - metabolism | Pseudoxanthoma Elasticum - metabolism | Alkaline Phosphatase - genetics | Phosphoric Diester Hydrolases - metabolism | Signal Transduction | Cells, Cultured | Gene Expression Regulation | Phosphoric Diester Hydrolases - genetics | Pseudoxanthoma Elasticum - pathology | Transforming Growth Factor beta1 - genetics | Fibroblasts - pathology | Pyrophosphatases - metabolism | Elastic Tissue - pathology | Pseudoxanthoma Elasticum - genetics | Calcinosis - pathology | Multidrug Resistance-Associated Proteins - metabolism | Phosphates | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2015, Volume 10, Issue 12, pp. e0145478 - e0145478
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 17779 - 14
Diminished microRNA-29b levels have recently been revealed to provoke increased expression and accumulation of extracellular matrix molecules, such as... 
FIBROSIS | MIR-29 | COLLAGEN EXPRESSION | SERUM XYLOSYLTRANSFERASE | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | FUNCTIONAL-ANALYSIS | GENE-EXPRESSION | MECHANISMS | IDENTIFICATION | MYOFIBROBLAST DIFFERENTIATION | Transfection | MicroRNAs | Collagen | Fibrosis | MiRNA | Fibroblasts | Extracellular matrix | Skin | Gene expression | Sp1 protein | Binding sites
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 06/2016, Volume 57, Issue 7, pp. 3323 - 3330
Journal Article
JAMA Ophthalmology, ISSN 2168-6165, 05/2015, Volume 133, Issue 5, pp. 581 - 588
Journal Article
Scientific Reports, ISSN 2045-2322, 07/2015, Volume 5, Issue 1, pp. 12537 - 12537
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2014, Volume 9, Issue 9, pp. e108336 - e108336
Mutations in the ABC transporter ABCC6 were recently identified as cause of Pseudoxanthoma elasticum ( PXE), a rare genetic disorder characterized by... 
XYLOSYLTRANSFERASE-I | PROTEIN MATURATION | MULTIDISCIPLINARY SCIENCES | TRANSPORT ACTIVITY | MUTATION | GENE-EXPRESSION | PXE PATIENTS | RESISTANCE | SERUM WITHDRAWAL | ABC TRANSPORTERS | THYMOSIN BETA-4 | Metabolomics | Oxidative Stress | Glycerophospholipids - classification | Dipeptides - biosynthesis | Humans | Extracellular Matrix - metabolism | Multidrug Resistance-Associated Proteins - biosynthesis | Fatty Acids - classification | Guanine - metabolism | RNA Interference | HEK293 Cells | Multidrug Resistance-Associated Proteins - genetics | Dermis - cytology | Pantothenic Acid - metabolism | Fibroblasts - metabolism | Cell Line | Pseudoxanthoma Elasticum - metabolism | Gene Expression | Dermis - metabolism | Purines - metabolism | Glycerophospholipids - biosynthesis | Pseudoxanthoma Elasticum - pathology | Mutation - genetics | Elastic Tissue - pathology | Pseudoxanthoma Elasticum - genetics | Dermis - pathology | RNA, Small Interfering | Calcinosis - pathology | Fatty Acids - biosynthesis | Oxidative stress | Diabetic retinopathy | Cell culture | Energy metabolism | Peptides | Pathogenesis | Amino acids | Lipids | Biology | Biochemistry | Nucleotides | Leucine | Kinases | Cofactors | Guanine | Fibers | Alterations | Metabolites | Mineralization | Fibroblasts | Extracellular matrix | Xenobiotics | Growth factors | Carbohydrates | Polypeptides | Mass spectroscopy | Metabolism | Gene expression | Patients | Vitamins | Studies | Calcification | Skin | Mutation | Mass spectrometry | Transporter | ABC transporter | Index Medicus
Journal Article
LIPIDS IN HEALTH AND DISEASE, ISSN 1476-511X, 01/2019, Volume 18, Issue 1, pp. 2 - 2
Journal Article
Journal Article