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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2014, Volume 111, Issue 25, pp. 9145 - 9150
Journal Article
PLOS ONE, ISSN 1932-6203, 11/2015, Volume 10, Issue 11, p. e0141991
Multidrug transporters mediate the active extrusion of antibiotics and toxic ions from the cell. This reaction is thought to be based on a switch of the... 
Binding | Efflux | Lactococcus lactis | Fluorescent dyes | Fluorescence | Crosslinking | Biochemistry | Drug delivery | Fluorescent indicators | Glucose | Metabolism | Gene expression | Substrates | Mammalian cells | Proteins | Microorganisms | Antibiotics | Extrusion | Distance measurement | Electron paramagnetic resonance | Transporter | Binding sites | Conformation
Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 1336 - 11
Journal Article
Nature reviews. Microbiology, ISSN 1740-1526, 09/2018, Volume 16, Issue 9, pp. 577 - 577
In the version of this Review originally published, the author contributions of co-author Arthur Neuberger were incorrectly listed. The author contributions... 
Efflux | Structure-function relationships
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 12/2015, p. jbc.M115.694901
This article has been withdrawn by the authors. Some lanes in the immunoblots were used to represent different experimental conditions in Figs 3A and 5A. The... 
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2012, Volume 7, Issue 6, pp. e38715 - e38715
Journal Article
Trends in Microbiology, ISSN 0966-842X, 05/2015, Volume 23, Issue 5, pp. 311 - 319
Microorganisms encode several classes of transmembrane pumps that can expel an enormous range of toxic substances, thereby improving their fitness in harsh... 
Journal Article
The EMBO Journal, ISSN 0261-4189, 06/2000, Volume 19, Issue 11, pp. 2503 - 2514
The bacterial LmrA protein and the mammalian multidrug resistance P-glycoprotein are closely related ATP-binding cassette (ABC) transporters that confer... 
multidrug resistance | membrane protein | drug efflux | LmrA | transport mechanism | Transport mechanism | Membrane protein | Drug efflux | Multidrug resistance | RESISTANCE P-GLYCOPROTEIN | MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SECONDARY | CATALYTIC TRANSITION-STATE | CELL BIOLOGY | NUCLEOTIDE | MDR1 | LABELING SITES | DRUG-INTERACTION SITES | TERTIARY STRUCTURE CHANGES | LACTOCOCCUS-LACTIS | Vinblastine - metabolism | Lactococcus lactis | Allosteric Regulation | Bacterial Proteins - chemistry | Recombinant Fusion Proteins - physiology | ATP-Binding Cassette Transporters - physiology | ATP-Binding Cassette Transporters - chemistry | Biological Transport, Active | Isoquinolines - pharmacology | Adenosine Triphosphate - metabolism | Vanadates - pharmacology | ATP-Binding Cassette, Sub-Family B, Member 1 - chemistry | Cell Membrane - metabolism | Catalysis | Binding Sites | Dimerization | Drug Resistance, Multiple - physiology | Protein Structure, Tertiary | Photoaffinity Labels | Mutagenesis, Site-Directed | Models, Molecular | Cell Membrane - ultrastructure | Bacterial Proteins - physiology | Calcium Channel Blockers - pharmacology | ATP-Binding Cassette, Sub-Family B, Member 1 - physiology | Adenosine Diphosphate - pharmacology | Benzimidazoles - metabolism | Liposomes | Quinazolines - pharmacology | Multidrug Resistance-Associated Proteins | Multidrug transport | LmrA protein | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 10/2010, Volume 467, Issue 7318, pp. 926 - 927
  In the past decade, crystal structures have been determined for multidrug transporters belonging to four families: the major facilitator superfamily (MFS),... 
Proteins | Biochemistry | Drug resistance | Binding sites | Crystal structure
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2012, Volume 7, Issue 6, pp. e37845 - e37845
ABC transporters use the energy from binding and hydrolysis of ATP to import or extrude substrates across the membrane. Using ribosome display, we raised... 
ANKYRIN REPEAT PROTEIN | MALTOSE TRANSPORTER | ESCHERICHIA-COLI | BIOLOGY | RIBOSOME DISPLAY | PHAGE DISPLAY | MULTIDRUG-RESISTANCE | MONOCLONAL-ANTIBODIES | MEMBRANE-PROTEINS | LACTOCOCCUS-LACTIS | ATP-BINDING | Recombinant Proteins - metabolism | Solubility - drug effects | Surface Plasmon Resonance | Detergents - pharmacology | Epitope Mapping | Enzyme-Linked Immunosorbent Assay | Proteolipids - metabolism | Adenosine Triphosphatases - metabolism | Biophysical Phenomena - drug effects | Daunorubicin - pharmacology | Ribosomes - metabolism | Lactococcus lactis - metabolism | Ankyrin Repeat | Proteolipids - drug effects | Epitopes - immunology | Pharmaceutical Preparations - metabolism | Protein Binding - drug effects | Ribosomes - drug effects | ATP-Binding Cassette Transporters - metabolism | Biological Transport - drug effects | Cell Membrane - metabolism | Cell Membrane - drug effects | Lactococcus lactis - drug effects | Proteins | Hydrolysis | Adenosine triphosphatase | Antigenic determinants | Protein binding | Binding | Efflux | Lactococcus lactis | Membranes | Yeast | Energy use | Cloning | Homology | Biochemistry | Pharmacology | Genomes | Fluorides | Epitopes | Binders | Substrates | Molecular modelling | In vivo methods and tests | ABC transporters | Ankyrin | Transporter | ABC transporter | Pharmaceuticals | Index Medicus
Journal Article