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Journal of Clinical Oncology, ISSN 0732-183X, 02/2018, Volume 36, Issue 4_suppl, pp. 335 - 335
Journal Article
The Lancet, ISSN 0140-6736, 07/2018, Volume 392, Issue 10143, pp. 232 - 243
More than 1·8 million new cases of HIV-1 infection were diagnosed worldwide in 2016. No licensed prophylactic HIV-1 vaccine exists. A major limitation to date... 
MEDICINE, GENERAL & INTERNAL | IPCAVD 001 | IMMUNOGENICITY | SAFETY | EFFICACY TRIAL | CELLULAR IMMUNE-RESPONSES | SIV CHALLENGES | ENV VACCINE | PREVENTION | INFECTION | PROTECTIVE EFFICACY | Back Pain - etiology | Abdominal Pain - etiology | Adenoviridae | Double-Blind Method | Aspartate Aminotransferases - analysis | Humans | Middle Aged | Fatigue - etiology | Macaca mulatta | Healthy Volunteers | AIDS Vaccines - adverse effects | Dose-Response Relationship, Drug | Young Adult | Dizziness - etiology | HIV-1 - immunology | Animals | Immunity, Humoral | Adolescent | Adult | Diarrhea - etiology | AIDS Vaccines - administration & dosage | Genetic Vectors | Immunity, Cellular | Clinical trials | Product development | Vaccines | HIV (Viruses) | Back pain | Pandemics | Laboratories | Aluminum | Viruses | Lymphocytes T | Monkeys | Infections | Dosage | Posture | Proteins | Prevention | Randomization | Pain | Gag protein | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Peripheral blood | Safety | Pharmaceutical industry | Vaccinia | Enzyme-linked immunosorbent assay | Binding | Antigens | Medical research | Phenotypes | Immune response | Effectiveness | Health risks | Diarrhea | Durability | Studies | Immunogenicity | Adenoviruses | Federal agencies | Aspartate aminotransferase | Phagocytosis
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 07/2017, Volume 23, Issue 14, pp. 3638 - 3648
Journal Article
British Journal of Cancer, ISSN 0007-0920, 10/2018, Volume 119, Issue 9, pp. 1086 - 1093
BACKGROUND: This phase 1 dose-escalation trial studied MM-302, a novel HER2-targeted PEGylated antibody-liposomal doxorubicin conjugate, in HER2-positive... 
EMTANSINE | POSITRON-EMISSION-TOMOGRAPHY | PERTUZUMAB PLUS TRASTUZUMAB | ONCOLOGY | CARDIOTOXICITY | ANTITUMOR-ACTIVITY | ANTHRACYCLINES | COMBINATION | DOCETAXEL | III TRIAL | DELIVERY | Brain - diagnostic imaging | Cyclophosphamide - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Receptor, ErbB-2 - genetics | Humans | Single-Chain Antibodies - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Immunoconjugates - pharmacokinetics | Cyclophosphamide - adverse effects | Immunoconjugates - administration & dosage | Dose-Response Relationship, Drug | Doxorubicin - analogs & derivatives | Adult | Female | Breast Neoplasms - diagnostic imaging | Doxorubicin - administration & dosage | Immunoconjugates - adverse effects | Drug Administration Schedule | Single-Chain Antibodies - adverse effects | Trastuzumab - adverse effects | Treatment Outcome | Trastuzumab - administration & dosage | Breast Neoplasms - drug therapy | Doxorubicin - pharmacokinetics | Breast Neoplasms - genetics | Single-Chain Antibodies - pharmacokinetics | Survival Analysis | Aged | Doxorubicin - adverse effects | Neuroimaging | Thrombocytopenia | Brain | Conjugates | Anemia | Mucosa | Brain tumors | Fatigue | Nausea | Breast cancer | Pharmacology | Patients | Doxorubicin | ErbB-2 protein | Metastases | Cyclophosphamide | Anthracycline | Pharmacokinetics | Trastuzumab | Cancer | Tumors | Neutropenia
Journal Article
Journal Article
Theranostics, ISSN 1838-7640, 2017, Volume 7, Issue 17, pp. 4229 - 4239
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 07/2012, Volume 262, Issue 1, pp. 1 - 10
Anthracycline-based regimens are a mainstay of early breast cancer therapy, however their use is limited by cardiac toxicity. The potential for cardiotoxicity... 
Safety sciences | Stem cell-derived cardiomyocytes | HER2-targeted liposomal doxorubicin | Cardiotoxicity | Doxorubicin | Preclinical safety | TRASTUZUMAB | EFFICACY | FAILURE | DELIVERY | PLATFORM | THERAPY | IMMUNOLIPOSOMES | METASTATIC BREAST-CANCER | PRECLINICAL MANUFACTURE | CONJUGATE | PHARMACOLOGY & PHARMACY | TOXICOLOGY | Antibiotics, Antineoplastic - toxicity | Antibiotics, Antineoplastic - pharmacology | Humans | Receptor, ErbB-2 - metabolism | Breast Neoplasms - drug therapy | Doxorubicin - toxicity | Drug Delivery Systems | Antibiotics, Antineoplastic - administration & dosage | Animals | Myocytes, Cardiac - drug effects | Signal Transduction - drug effects | Breast Neoplasms - pathology | Mice, Nude | Myocytes, Cardiac - metabolism | Female | Mice | Doxorubicin - pharmacology | Doxorubicin - administration & dosage | Induced Pluripotent Stem Cells - metabolism | Antimitotic agents | Anthracyclines | Care and treatment | Antineoplastic agents | Analysis | Cancer | Index Medicus | Drugs | Heart | Toxicity | Mortality | Data processing | Breast cancer | cardiomyocytes | trastuzumab | Signal transduction | Anthracycline | Cell death | Safety engineering | HEART | APOPTOSIS | MAMMARY GLANDS | NEOPLASMS | CLINICAL TRIALS | SAFETY | DOXORUBICIN | ANIMAL TISSUES | STEM CELLS | TOXICITY | 60 APPLIED LIFE SCIENCES
Journal Article
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