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Biophysical Journal, ISSN 0006-3495, 02/2017, Volume 112, Issue 3, pp. 475a - 475a
Journal Article
Biophysical Journal, ISSN 0006-3495, 01/2015, Volume 108, Issue 2, pp. 127a - 127a
Journal Article
Biophysical Journal, ISSN 0006-3495, 08/2014, Volume 107, Issue 3, p. 613
  EmrE is a small multidrug resistance transporter that has been well studied as a model for secondary active transport. Because transport requires the protein... 
Membranes | Nuclear magnetic resonance--NMR | Bacterial proteins | Biophysics | Drug resistance | Biological assays | Crystal structure
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2015, Volume 112, Issue 50, p. 15366
  Flux-dependent inactivation that arises from functional coupling between the inner gate and the selectivity filter is widespread in ion channels. The... 
Proteins | Ions | Binding sites | Crystal structure
Journal Article
The Journal of General Physiology, ISSN 0022-1295, 12/2015, Volume 146, Issue 6, p. 445
  The small multidrug resistance transporter EmrE is a homodimer that uses energy provided by the proton motive force to drive the efflux of drug substrates.... 
Protons | Drugs | Nuclear magnetic resonance--NMR | Asymmetry
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2017, Volume 114, Issue 47, p. E10083
EmrE is a small multidrug resistance transporter found in Escherichia coli that confers resistance to toxic polyaromatic cations due to its proton-coupled... 
Protons | Exchanging | Efflux | Drug delivery systems | Nuclear magnetic resonance--NMR | Multidrug resistance | Antiport | Substrates | Multidrug resistant organisms | E coli | Cations | Transport | Transporter
Journal Article
Biophysical Journal, ISSN 0006-3495, 01/2013, Volume 104, Issue 2, pp. 128a - 128a
Journal Article
Biophysical Journal, ISSN 0006-3495, 01/2012, Volume 102, Issue 3, pp. 215a - 215a
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2017, Volume 114, Issue 47, pp. E10083 - E10091
Journal Article
Analytical Biochemistry, ISSN 0003-2697, 05/2018, Volume 549, pp. 130 - 135
Membrane transporters are an important class of proteins which remain challenging to study. Transport assays are crucial to developing our understanding of... 
Membrane protein | Multidrug transporter | Membrane transport | Transport assay | Mass spectrometry | CHEMISTRY, ANALYTICAL | KINETICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | BIOCHEMICAL RESEARCH METHODS | RESISTANCE | CELL | membrane transport | mass spectrometry | membrane protein | multidrug transporter | transport assay
Journal Article
PLoS Pathogens, ISSN 1553-7366, 01/2014, Volume 10, Issue 1, p. e1003869
Journal Article
Biophysical Journal, ISSN 0006-3495, 07/2019, Volume 117, Issue 2, pp. 388 - 398
The voltage-sensing domain (VSD) is a conserved structural module that regulates the gating of voltage-dependent ion channels in response to a change in... 
DEPENDENT K+ CHANNEL | BIOPHYSICS | S3-S4 LINKER | CRYSTAL-STRUCTURE | TRANSITIONS | MEMBRANE-PROTEINS | SENSOR DOMAIN | CHARGE | CHANNEL GATING KINETICS | POTASSIUM CHANNEL | REVEALS | Molecular dynamics | Nuclear magnetic resonance spectroscopy | Analysis
Journal Article