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animals (30) 30
science & technology (28) 28
life sciences & biomedicine (24) 24
endocrinology & metabolism (17) 17
male (17) 17
digestive, oral, and skin physiology (15) 15
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obesity (13) 13
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eating - drug effects (7) 7
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receptors, glucagon - agonists (5) 5
receptors, glucagon - metabolism (5) 5
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diabetes. impaired glucose tolerance (4) 4
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endocrinology (4) 4
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glucagon (4) 4
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1. Full Text Targeting FXR and FGF19 to Treat Metabolic Diseases-Lessons Learned From Bariatric Surgery
by Bozadjieva, Nadejda and Heppner, Kristy M and Seeley, Randy J and Seeley, Randy J
Diabetes (New York, N.Y.), ISSN 0012-1797, 09/2018, Volume 67, Issue 9, pp. 1720 - 1728
Obesity, Morbid - surgery | Humans | Metabolic Diseases - drug therapy | Fibroblast Growth Factors - metabolism | Obesity, Morbid - physiopathology | Liver - drug effects | Enterohepatic Circulation - drug effects | Fibroblast Growth Factors - agonists | Bariatric Surgery - adverse effects | Obesity, Morbid - metabolism | Obesity, Morbid - therapy | Hypoglycemic Agents - therapeutic use | Molecular Targeted Therapy - adverse effects | Liver - metabolism | Gastrointestinal Microbiome | Bile Acids and Salts - metabolism | Receptors, Cytoplasmic and Nuclear - agonists | Combined Modality Therapy - adverse effects | Organ Specificity | Animals | Metabolic Diseases - metabolism | Signal Transduction - drug effects | Metabolic Diseases - etiology | Models, Biological | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Fibroblast Growth Factors - antagonists & inhibitors | Metabolic Diseases - microbiology | Receptors, Cytoplasmic and Nuclear - metabolism | Obesity | Care and treatment | Usage | Bile acids | Surgery | Metabolic diseases | Fibroblast growth factors | Health aspects | Glucose monitoring | Gastric bypass | Body weight loss | Glucose | Metabolism | Gastrectomy | Glucose metabolism | Microbiota | Molecular modelling | Acids | Gastrointestinal surgery | Intestinal microflora | Metabolic disorders | Index Medicus | Abridged Index Medicus | s in Diabetes | 0706
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2. Mechanisms in endocrinology: regulation of glucose metabolism by the ghrelin system: multiple players and multiple actions
by Heppner, Kristy M and Tong, Jenny
European journal of endocrinology, ISSN 0804-4643, 2014, Volume 171, Issue 1, pp. R21 - 32
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Ghrelin - metabolism | Animals | Humans | Glucose - metabolism | Receptors, Ghrelin - metabolism | Endocrinology | Acylation
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3. Regulation of glucose metabolism by the ghrelin system: Multiple players and multiple actions
by Heppner, Kristy M and Tong, Jenny
European journal of endocrinology, ISSN 0804-4643, 2014, Volume 171, Issue 1, pp. R21 - R32
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4. Full Text Fibroblast growth factor 21 mediates specific glucagon actions
by Habegger, Kirk M and Stemmer, Kerstin and Cheng, Christine and Müller, Timo D and Heppner, Kristy M and Ottaway, Nickki and Holland, Jenna and Hembree, Jazzminn L and Smiley, David and Gelfanov, Vasily and Krishna, Radha and Arafat, Ayman M and Konkar, Anish and Belli, Sara and Kapps, Martin and Woods, Stephen C and Hofmann, Susanna M and D'Alessio, David and Pfluger, Paul T and Perez-Tilve, Diego and Seeley, Randy J and Konishi, Morichika and Itoh, Nobuyujki and Kharitonenkov, Alexei and Spranger, Joachim and DiMarchi, Richard D and Tschöp, Matthias H
Diabetes (New York, N.Y.), ISSN 0012-1797, 05/2013, Volume 62, Issue 5, pp. 1453 - 1463
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Diabetes. Impaired glucose tolerance | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Obesity - drug therapy | Humans | Peptides - pharmacokinetics | Fibroblast Growth Factors - genetics | Male | Fibroblast Growth Factors - secretion | Obesity - blood | Anti-Obesity Agents - therapeutic use | Glucagon - agonists | Fibroblast Growth Factors - metabolism | Anti-Obesity Agents - pharmacokinetics | Peptides - chemical synthesis | Hepatocytes - secretion | Hypoglycemic Agents - therapeutic use | Receptors, Glucagon - agonists | Receptors, Glucagon - genetics | Hypoglycemic Agents - pharmacokinetics | Peptides - physiology | Rats | Hypoglycemic Agents - pharmacology | Mice, Knockout | Cross-Over Studies | Anti-Obesity Agents - chemical synthesis | Mice | Anti-Obesity Agents - pharmacology | Hepatocytes - pathology | Diabetes Mellitus, Type 2 - metabolism | Hepatocytes - metabolism | Molecular Targeted Therapy | Mice, Mutant Strains | HEK293 Cells | Adult | Female | Hepatocytes - drug effects | Recombinant Proteins - metabolism | Double-Blind Method | Cells, Cultured | Insulin Resistance | Receptors, Glucagon - metabolism | Recombinant Proteins - agonists | Glucagon - pharmacology | Obesity - metabolism | Diabetes Mellitus, Type 2 - blood | Animals | Fibroblast Growth Factors - blood | Hypoglycemic Agents - chemical synthesis | Glucagon - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Peptides - therapeutic use | Physiological aspects | Fibroblast growth factors | Research | Glucagon | Analysis | Index Medicus | Abridged Index Medicus | Original Research
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5. Full Text GLP-1 based therapeutics: Simultaneously combating T2DM and obesity
by Heppner, Kristy M and Perez-Tilve, Diego
Frontiers in neuroscience, ISSN 1662-4548, 03/2015, Volume 9, pp. 92 - 92
Obesity | CNS | GLP-1 | Diabetes | Insulin | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Energy metabolism | Peptides | Glucagon | Secretion | Diabetes mellitus | Homeostasis | Body weight loss | Glucose | Metabolism | Monkeys & apes | Glucose metabolism | Weight control | Agonists | Pancreas | Glucagon-like peptide 1 | diabetes
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6. Full Text The metabolic actions of glucagon revisited
by Heppner, Kristy M and Geary, Nori and Bartness, Timothy J and Habegger, Kirk M and DiMarchi, Richard and Tschöp, Matthias H
Nature reviews. Endocrinology, ISSN 1759-5029, 12/2010, Volume 6, Issue 12, pp. 689 - 697
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Humans | Glucagon - physiology | Metabolism - physiology | Glucagon - pharmacology | Obesity - metabolism | Adipose Tissue - metabolism | Animals | Models, Biological | Metabolism - drug effects | Lipid Metabolism - drug effects | Energy Metabolism - physiology | Adipose Tissue - drug effects | Energy Metabolism - drug effects | Lipid Metabolism - physiology | Metabolism - genetics | Physiological aspects | Obesity | Care and treatment | Research | Metabolic syndrome X | Glucagon | Index Medicus
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7. Full Text Both acyl and des-acyl ghrelin regulate adiposity and glucose metabolism via central nervous system ghrelin receptors
by Heppner, Kristy M and Piechowski, Carolin L and Müller, Anne and Ottaway, Nickki and Sisley, Stephanie and Smiley, David L and Habegger, Kirk M and Pfluger, Paul T and DiMarchi, Richard and Biebermann, Heike and Tschöp, Matthias H and Sandoval, Darleen A and Perez-Tilve, Diego
Diabetes (New York, N.Y.), ISSN 0012-1797, 01/2014, Volume 63, Issue 1, pp. 122 - 131
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Adiposity - drug effects | Animals | Central Nervous System - metabolism | Ghrelin - administration & dosage | Humans | HEK293 Cells | Glucose - metabolism | Receptors, Ghrelin - metabolism | Ghrelin - pharmacology | Adiposity - physiology | Mice | Infusions, Intraventricular | Glucose metabolism | Cell receptors | Genetic aspects | Properties | Ghrelin | Identification and classification | Growth hormones | Glucose | Comparative analysis | Insulin | Rodents | Index Medicus | Abridged Index Medicus | Metabolism
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8. Full Text Direct control of brown adipose tissue thermogenesis by central nervous system glucagon-like peptide-1 receptor signaling
by Lockie, Sarah H and Heppner, Kristy M and Chaudhary, Nilika and Chabenne, Joseph R and Morgan, Donald A and Veyrat-Durebex, Christelle and Ananthakrishnan, Gayathri and Rohner-Jeanrenaud, Françoise and Drucker, Daniel J and DiMarchi, Richard and Rahmouni, Kamal and Oldfield, Brian J and Tschöp, Matthias H and Perez-Tilve, Diego
Diabetes (New York, N.Y.), ISSN 0012-1797, 11/2012, Volume 61, Issue 11, pp. 2753 - 2762
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Diabetes. Impaired glucose tolerance | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Up-Regulation | Central Nervous System - metabolism | Ion Channels - genetics | Male | Mitochondrial Proteins - genetics | Scapula | Sympathetic Nervous System - metabolism | Adipose Tissue, Brown - innervation | Glucagon-Like Peptide 1 - agonists | Mitochondrial Proteins - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Trans-Activators - genetics | Neurons - metabolism | Oxyntomodulin - metabolism | Receptors, Glucagon - agonists | Receptors, Glucagon - genetics | Glucagon-Like Peptide 1 - metabolism | Signal Transduction | Mice, Inbred C57BL | Insulin Resistance | Receptors, Glucagon - metabolism | Nerve Tissue Proteins - genetics | Mice, Knockout | Nerve Tissue Proteins - metabolism | Animals | Thermogenesis | Glucagon-Like Peptide-1 Receptor | Ion Channels - metabolism | Glucagon - metabolism | Trans-Activators - metabolism | Adipose Tissue, Brown - metabolism | Mice | Transcription Factors | Uncoupling Protein 1 | Physiological aspects | Brown adipose tissue | Research | Analysis | Index Medicus | Abridged Index Medicus | Metabolism
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9. Full Text FGF21 decreases body weight without reducing food intake or bone mineral density in high-fat fed obese rhesus macaque monkeys
by Andersen, Birgitte and Straarup, Ellen M and Heppner, Kristy M and Takahashi, Diana L and Raffaele, Virginia and Dissen, Gregory A and Lewandowski, Katherine and Bödvarsdottir, Thóra B and Raun, Kirsten and Grove, Kevin L and Kievit, Paul
International Journal of Obesity, ISSN 0307-0565, 06/2018, Volume 42, Issue 6, pp. 1151 - 1160
Endocrinology & Metabolism | Life Sciences & Biomedicine | Nutrition & Dietetics | Science & Technology | Glucose Tolerance Test | Anti-Obesity Agents - administration & dosage | Obesity - drug therapy | Blood Glucose | Fibroblast Growth Factors - pharmacology | Macaca mulatta | Weight Loss - drug effects | Eating - physiology | Obesity - metabolism | Dose-Response Relationship, Drug | Eating - drug effects | Bone Density - drug effects | Animals | Fibroblast Growth Factors - administration & dosage | Diet, High-Fat | Weight Loss - physiology | Energy Metabolism - physiology | Hydrocortisone - blood | Anti-Obesity Agents - pharmacology | Energy Metabolism - drug effects | Disease Models, Animal | Obesity | Care and treatment | Physiological aspects | Models | Fibroblast growth factors | Health aspects | Ketogenic diet | Lipoproteins (low density) | Animal models | Body weight | Dyslipidemia | Clinical trials | Lipids | Monkeys | Hormones | Glucose | Males | Drug development | Hydrocortisone | Composition effects | Body composition | High fat diet | Bone resorption | Glucose metabolism | Body composition (biology) | Bone density | Lipid metabolism | Bone composition | Food | Dual energy X-ray absorptiometry | Medical research | Ovariectomy | Diabetes mellitus | Markers | Triglycerides | Metabolism | Insulin | Cholesterol | Bone mineral content | Glucose tolerance | Organic chemistry | Sensitivity | Side effects | Food intake | Collagen | Weight reduction | Bone mineral density | Females | Index Medicus
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