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Nature, ISSN 0028-0836, 2014, Volume 510, Issue 7504, pp. 268 - 272
Journal Article
Blood, ISSN 0006-4971, 11/2011, Volume 118, Issue 21, pp. 2955 - 2955
Abstract Abstract 2955 Emerging evidence shows that many cancers are organized as cellular hierarchies sustained by a subpopulation of cancer stem cells (CSC).... 
Journal Article
Blood, ISSN 0006-4971, 11/2013, Volume 122, Issue 21, pp. 1648 - 1648
Abstract Acute Myeloid Leukemia (AML) is a heterogeneous disease with a relapse rate of up to 80% depending on patient age and AML subtype. AML is organized as... 
Journal Article
Cancer Research, ISSN 0008-5472, 04/2012, Volume 72, Issue 8 Supplement, pp. 3330 - 3330
Journal Article
Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 8 Supplement, pp. 2292 - 2292
Journal Article
Cancer Cell, ISSN 1535-6108, 06/2012, Volume 21, Issue 6, pp. 777 - 792
There is increasing evidence that some cancers are hierarchically organized, sustained by a relatively rare population of cancer-initiating cells (C-ICs).... 
HUMAN COLORECTAL-CARCINOMA | STEM-CELLS | ONCOLOGY | INDUCED APOPTOSIS | PROTECTIVE ROLE | PROSTATE-CANCER | DNA-DAMAGE | ACUTE MYELOID-LEUKEMIA | ID-1 PROTEIN | EXPRESSION | HUMAN PANCREATIC-CANCER | CELL BIOLOGY | Cell Cycle - genetics | Colonic Neoplasms - genetics | Neoplastic Stem Cells - drug effects | Colonic Neoplasms - drug therapy | Humans | Gene Expression Regulation, Neoplastic | Spheroids, Cellular - pathology | Inhibitor of Differentiation Proteins - genetics | Neoplasm Proteins - metabolism | Organoplatinum Compounds - pharmacology | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Neoplastic Stem Cells - metabolism | RNA Interference | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Neoplastic Stem Cells - pathology | Antineoplastic Agents - pharmacology | Spheroids, Cellular - drug effects | Tumor Cells, Cultured | Neoplasm Proteins - genetics | Spheroids, Cellular - metabolism | Inhibitor of Differentiation Proteins - metabolism | Inhibitor of Differentiation Protein 1 - metabolism | Mice, SCID | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Xenograft Model Antitumor Assays | Microscopy, Confocal | Animals | Colonic Neoplasms - pathology | Inhibitor of Differentiation Protein 1 - genetics | Mice, Inbred NOD | Cell Proliferation - drug effects | Mice | Cell Cycle - drug effects | Chemotherapy | Genes | Cancer | Tumors
Journal Article
Journal Article
Cancer Cell, ISSN 1535-6108, 02/2016, Volume 29, Issue 2, pp. 214 - 228
Journal Article
Journal Article
Cell Stem Cell, ISSN 1934-5909, 09/2016, Volume 19, Issue 3, pp. 383 - 396
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 3824 - 3824
Abstract Background: Residing at the apex of the blood system hierarchy, hematopoietic stem cells (HSCs) are endowed with multi-potency and self-renewal... 
Journal Article
Journal of Hydrology, ISSN 0022-1694, 12/2017, Volume 555, pp. 407 - 419
Geophysical data have proven to be very useful for lithological characterization. However, quantitatively integrating the information gained from acquiring... 
Rock-physics | Multiple point statistics | Recharge | Geophysics | Aquifer recharge and recovery | TOMOGRAPHY | WATER RESOURCES | FILTRATION | SIMULATION | FLOW | ENGINEERING, CIVIL | GEOSCIENCES, MULTIDISCIPLINARY | TRACE ORGANIC-CHEMICALS | UNCERTAINTY | REPRODUCTION
Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 4267 - 4267
Abstract Therapy-resistant leukemic stem cells (LSCs) sustain acute myeloid leukemia (AML) and must be eliminated to cure a patient. However, there are no... 
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 3579 - 3579
Abstract The multistep pathogenesis of Down Syndrome (DS)-associated pre-leukemia and subsequent progression to acute leukemia is one of the better... 
Journal Article
SCIENCE TRANSLATIONAL MEDICINE, ISSN 1946-6234, 12/2017, Volume 9, Issue 421, p. eaag3214
Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative therapy, but the large number of HSCs required limits its widespread use. Host... 
MEDICINE, RESEARCH & EXPERIMENTAL | IN-VITRO | INTERFERON-GAMMA | SELF-RENEWAL | NECROSIS-FACTOR-ALPHA | UMBILICAL-CORD BLOOD | MARROW-TRANSPLANTATION | HEMATOLOGIC MALIGNANCY | VERSUS-HOST-DISEASE | TERM MULTILINEAGE ENGRAFTMENT | FACTOR RECEPTOR | CELL BIOLOGY
Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 900 - 900
Abstract Recent studies have shown that several miRNA are differentially expressed in hematopoietic stem cells (HSC) and involved in regulating self-renewal,... 
Journal Article