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PLoS ONE, ISSN 1932-6203, 10/2016, Volume 11, Issue 10, p. e0164370
To explore novel genetic abnormalities occurring in myelodysplastic syndromes (MDS) through an integrative study combining array-based comparative genomic... 
PROGNOSTIC SCORING SYSTEM | NORMAL KARYOTYPE | COPY NUMBER ALTERATIONS | SNP-ARRAY | MULTIDISCIPLINARY SCIENCES | CRYPTIC CHROMOSOMAL LESIONS | CHRONIC LYMPHOCYTIC-LEUKEMIA | ACUTE MYELOID-LEUKEMIA | MUTATIONS | CANCER GENOMES | CHRONIC MYELOMONOCYTIC LEUKEMIA | Recurrence | Humans | Middle Aged | Male | Risk | Tumor Suppressor Protein p53 - genetics | DNA Copy Number Variations | Young Adult | DNA Mutational Analysis | Aged, 80 and over | Adult | Female | Child | Proto-Oncogene Proteins - genetics | DNA - metabolism | DNA-Binding Proteins - genetics | DNA - isolation & purification | DNA (Cytosine-5-)-Methyltransferases - genetics | DNA - chemistry | Myelodysplastic Syndromes - diagnosis | Comparative Genomic Hybridization | Adolescent | Chromosome Aberrations | Chromosomes, Human, Pair 13 | Aged | High-Throughput Nucleotide Sequencing | Myelodysplastic Syndromes - genetics | Myelodysplastic Syndromes - pathology | Core Binding Factor Alpha 2 Subunit - genetics | Karyotype | Medical research | Methyltransferases | Genes | Genomics | Medicine, Experimental | Cytogenetics | Genomes | Comparative analysis | Tumor proteins | Health aspects | Myelodysplastic syndromes | Copy number | p53 Protein | Leukemia | Disorders | Hybridization | Gene deletion | DNA repair | Neoplasms | Myelodysplastic syndrome | Genetic abnormalities | Clonal deletion | Deletion | Chromosome 13 | Chromosomes | Deoxyribonucleic acid--DNA | BRCA2 protein | Sequences | Risk groups | Abnormalities | Runx1 protein | Breast cancer | Patients | Studies | Genetic engineering | Mutation | Cancer | Tumors | Deoxyribonucleic acid | DNA
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, p. e0148972
Identifying additional genetic alterations associated with poor prognosis in acute lymphoblastic leukemia (ALL) is still a challenge. Aims: To characterize the... 
PEDIATRIC DISEASE | MULTIDISCIPLINARY SCIENCES | CONCERTED ACTION REPORT | HYBRIDIZATION | GLUCOCORTICOID RESISTANCE | CHROMOTHRIPSIS | MINIMAL RESIDUAL DISEASE | CANCER GENOMES | CHILDHOOD | CHEMOTHERAPY INCLUDING RITUXIMAB | CHROMOSOMAL REARRANGEMENTS | Multivariate Analysis | Humans | Middle Aged | Child, Preschool | Infant | Male | Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality | DNA Copy Number Variations | Young Adult | Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy | Aged, 80 and over | Adult | Female | Child | Infant, Newborn | Genetic Predisposition to Disease | Genome-Wide Association Study | Gene Frequency | Kaplan-Meier Estimate | Proportional Hazards Models | Treatment Outcome | Gene Dosage | Genetic Markers | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Comparative Genomic Hybridization | Adolescent | Aged | Biomarkers, Tumor - genetics | Genetic markers | Prognosis | Genetic variation | Physiological aspects | Genetic aspects | Acute lymphocytic leukemia | Research | Pediatrics | Copy number | Leukemia | Genomes | Parameter identification | Blood | Alterations | Cell cycle | Classification | Bone marrow | Children | Lesions | Deoxyribonucleic acid--DNA | Medical research | Acute lymphatic leukemia | Hematology | Markers | Lymphatic leukemia | Survival | Patients | Studies | DNA microarrays | Medical prognosis | Cytogenetics | Adults | Cancer | Apoptosis | Deoxyribonucleic acid | DNA
Journal Article
Journal Article
British Journal of Cancer, ISSN 0007-0920, 07/2017, Volume 117, Issue 2, pp. 256 - 265
Journal Article
European Journal of Haematology, ISSN 0902-4441, 02/2017, Volume 98, Issue 2, pp. 142 - 148
Journal Article
Journal Article
Annals of Hematology, ISSN 0939-5555, 11/2013, Volume 92, Issue 11, pp. 1543 - 1552
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 4942 - 4942
Abstract Type 1 Gaucher disease (GD1) is caused by the deficiency in the lysosomal enzyme glucocerebrosidase and causes the accumulation of glucocerebroside... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 4339 - 4339
Abstract Background and Aim:It is increasingly recognized that patients with a de novomyelodysplastic syndrome (MDS) onset as young adults, lacking any other... 
Journal Article
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 1036 - 1036
Abstract Introduction: The Wilms’ tumor 1 (WT1) gene, located on chromosome 11p13, encodes a transcription factor. WT1 is overexpressed in 90% of patients with... 
Journal Article
Blood, ISSN 0006-4971, 11/2012, Volume 120, Issue 21, pp. 1723 - 1723
Abstract Abstract 1723 Introduction and Objective: A large number of patients with low-risk myelodysplastic syndrome (MDS) need blood transfusions, being iron... 
Journal Article
Blood, ISSN 0006-4971, 11/2013, Volume 122, Issue 21, pp. 1329 - 1329
Abstract Introduction The Wilms' tumor 1 (WT1) gene, located on chromosome 11p13, encodes a transcription factor with both oncogene and tumor suppressor... 
Journal Article
European Journal of Haematology, ISSN 0902-4441, 07/2012, Volume 89, Issue 1, pp. 37 - 41
Objectives The myeloproliferative neoplasms displaying a PDGFRB rearrangement are rare diseases derived from a haematopoietic stem cell. The goals of the study... 
PDGFRB rearrangement | myeloproliferative neoplasms (MPNs) | fluorescence in situ hybridisation (FISH) | atypical CML (aCML) | cytogenetics | chronic myelomonocytic leukaemia (CMML) | Myeloproliferative neoplasms (MPNs) | Cytogenetics | Fluorescence in situ hybridisation (FISH) | Chronic myelomonocytic leukaemia (CMML) | Atypical CML (aCML) | TRANSLOCATIONS | DISORDERS | CLASSIFICATION | CHRONIC MYELOID-LEUKEMIA | BETA | GROWTH-FACTOR RECEPTOR | DISEASES | TARGETS | HEMATOLOGY | FUSION GENES | IMATINIB MESYLATE | Piperazines - administration & dosage | Translocation, Genetic | Follow-Up Studies | Humans | Middle Aged | Bone Marrow Neoplasms - epidemiology | Male | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Bone Marrow Neoplasms - genetics | Receptor, Platelet-Derived Growth Factor beta - genetics | Myeloproliferative Disorders - genetics | Incidence | Aged, 80 and over | Myeloproliferative Disorders - epidemiology | Adult | Female | Pyrimidines - administration & dosage | In Situ Hybridization, Fluorescence | Treatment Outcome | Myeloproliferative Disorders - drug therapy | Piperazines - therapeutic use | Imatinib Mesylate | Protein Kinase Inhibitors - administration & dosage | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | Aged | Bone Marrow Neoplasms - drug therapy | Benzamides
Journal Article