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Alcoholism: Clinical and Experimental Research, ISSN 0145-6008, 11/2013, Volume 37, Issue 11, pp. 1838 - 1848
Background Transforming growth factor beta 1 (TGF‐β1) is a pleiotropic cytokine that activates hepatic stellate cell (HSC) proliferation, but inhibits... 
Liver Fibrosis | Proliferation | TGF‐β1 | PDGF‐β Receptor | Hepatic Stellate Cells | TGF-β1 | PDGF-β Receptor
Journal Article
American Journal of Pathology, ISSN 0002-9440, 2014, Volume 184, Issue 5, pp. 1458 - 1467
Journal Article
American Journal of Pathology, The, ISSN 0002-9440, 2014, Volume 184, Issue 5, pp. 1458 - 1467
Alcohol-induced liver fibrosis and eventually cirrhosis is a leading cause of death. Acetaldehyde, the first metabolite of ethanol, up-regulates expression of... 
Pathology
Journal Article
Experimental and Clinical Endocrinology & Diabetes, ISSN 0947-7349, 02/2019
Abstract The expansion of adipose tissue is regulated by insulin and leptin through SREBP-1c, up-regulating lipogenesis in tissues by SCD1 enzyme, while ATGL... 
Article
Journal Article
Journal Article
Alcoholism: Clinical and Experimental Research, ISSN 0145-6008, 04/2008, Volume 32, Issue 4, pp. 559 - 566
Background:  The diverse incidence of alcoholic cirrhosis around the world and the fact that not all alcoholic drinkers develop liver disease indicates that... 
Alcohol | Genetic Factors | Liver Damage | APOE Polymorphism
Journal Article
IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, ISSN 2008-3866, 06/2019, Volume 22, Issue 6, pp. 623 - 630
Objective(s): The present study aimed to evaluate the receptor of advanced glycation end-products (RAGE), NF-kB, NRF2 gene expression, and RAGE cell... 
MEDICINE, RESEARCH & EXPERIMENTAL | Obesity | Oxidative stress | Receptor for advanced - glycation end products | Insulin resistance | PHARMACOLOGY & PHARMACY | AGER protein human | Original | Receptor for advanced glycation end products | insulin resistance
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 12/2013, Volume 65, pp. 1487 - 1496
We investigated whether the fibrogenic actions of acetaldehyde, the immediate oxidation product of ethanol, are mediated via Wingless (WNT) and/or β-catenin... 
Oxidative stress | β-Catenin | Hepatic stellate cells | Nucleoredoxin | Acetaldehyde | WNT SIGNALING PATHWAY | ACTIVATION | TGF-BETA | COLLAGEN | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIVER FIBROSIS | RECEPTOR | PROLIFERATION | INSULIN | ENDOCRINOLOGY & METABOLISM | beta-Catenin | GENE-EXPRESSION | UP-REGULATION | Oxidoreductases - antagonists & inhibitors | Reactive Oxygen Species - metabolism | Humans | Hepatic Stellate Cells - metabolism | Glycogen Synthase Kinase 3 beta | Aldehydes - metabolism | Receptor, Platelet-Derived Growth Factor beta - genetics | Wnt Proteins - metabolism | RNA, Messenger - biosynthesis | Glutathione - biosynthesis | Collagen Type I - genetics | Nuclear Proteins - biosynthesis | RNA Interference | Acetaldehyde - pharmacology | Dishevelled Proteins | Hepatic Stellate Cells - drug effects | Oxidoreductases - biosynthesis | Ethanol - metabolism | Phosphoproteins - biosynthesis | Glycogen Synthase Kinase 3 - biosynthesis | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Liver Cirrhosis, Alcoholic - pathology | Intercellular Signaling Peptides and Proteins | Cells, Cultured | beta Catenin - metabolism | beta Catenin - genetics | Ethanol - chemistry | beta Catenin - antagonists & inhibitors | Active Transport, Cell Nucleus - drug effects | Genes, myc - genetics | Nuclear Proteins - antagonists & inhibitors | Adaptor Proteins, Signal Transducing - biosynthesis | RNA, Small Interfering | Oxidative Stress - drug effects | Receptor, Platelet-Derived Growth Factor beta - biosynthesis
Journal Article
Journal Article
Scandinavian Journal of Clinical and Laboratory Investigation, ISSN 0036-5513, 04/2019, Volume 79, Issue 3, pp. 218 - 224
Most quantitative real-time PCR (qPCR) detection methods use two types of chemistries to measure the expression levels of ChREBP isoforms, hydrolysis probes... 
molecular probes | CHREBP protein human | quantitative real-time PCR | obesity | biopsies | MEDICINE, RESEARCH & EXPERIMENTAL | TAQMAN | TRANSCRIPTION | SYBR GREEN | ELEMENT-BINDING PROTEIN | PCR ASSAYS
Journal Article
Journal Article
Alcoholism: Clinical and Experimental Research, ISSN 0145-6008, 11/2013, Volume 37, Issue 11, pp. 1838 - 1848
Transforming growth factor beta 1 (TGF- beta 1) is a pleiotropic cytokine that activates hepatic stellate cell (HSC) proliferation, but inhibits parenchymal... 
1-Phosphatidylinositol 3-kinase
Journal Article
Scandinavian journal of clinical and laboratory investigation, 02/2019, p. 1
Most quantitative real-time PCR (qPCR) detection methods use two types of chemistries to measure the expression levels of ChREBP isoforms, hydrolysis probes... 
Journal Article
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 12/2013, Volume 65, p. 1487
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.freeradbiomed.2013.07.017... 
Glucose metabolism | Liver diseases | Platelet-derived growth factor | Synthesis | RNA | Glycogen | Collagen | Genetic engineering | Health aspects | Acetaldehyde
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 11/2004, Volume 287, Issue 5, pp. G974 - G987
Transforming growth factor-β1 (TGF-β1), the main cytokine involved in liver fibrogenesis, induces expression of the type I collagen genes in hepatic stellate... 
Collagen degradation | Collagenase | Fibrogenesis | Fibrosis
Journal Article
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