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ACS Medicinal Chemistry Letters, ISSN 1948-5875, 10/2019, Volume 10, Issue 1, pp. 62 - 66
A series of derivatives of the potent dual soluble epoxide hydrolase (sEH)/5-lipoxygenase-activating protein (FLAP) inhibitor diflapolin was designed,... 
Inflammation | 5-Lipoxygenase activating protein (FLAP) | Diflapolin | Soluble epoxide hydrolase (sEH) | Arachidonic acid cascade | SOLUBLE EPOXIDE HYDROLASE | MULTIPLE LIGANDS | CHEMISTRY, MEDICINAL | BIOSYNTHESIS | LICOFELONE | DISCOVERY
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 05/2008, Volume 14, Issue 15, pp. 4725 - 4730
A new catalytic asymmetric Henry reaction has been developed that uses a C1‐symmetric chiral aminopyridine ligand derived from camphor and picolylamine. A... 
aldol reaction | copper | antifungal agents | asymmetric catalysis | nucleophilic addition | Aldol reaction | Copper | Asymmetric catalysis | Antifungal agents | Nucleophilic addition
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 03/2011, Volume 17, Issue 13, pp. 3768 - 3773
Journal Article
Tetrahedron: Asymmetry, ISSN 0957-4166, 2006, Volume 17, Issue 14, pp. 2046 - 2049
Chiral iminopyridines prepared in a modular fashion from monoterpenic (camphor-derived) ketones and pyridinylalkylamines catalyze the enantioselective Henry... 
ASYMMETRIC CATALYSIS | ACID | REAGENTS | ALPHA-KETO ESTERS | COMPLEXES | CHEMISTRY, ORGANIC | CHEMISTRY, PHYSICAL | ALDEHYDES | CHEMISTRY, INORGANIC & NUCLEAR | ALKOXIDE-PROMOTED ADDITION | DIELS-ALDER REACTION | DERIVATIVES | ALLYLIC SUBSTITUTIONS | Copper compounds | Enantiomers
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2018, Volume 61, Issue 23, pp. 10724 - 10738
Intracellular elevation of E2 levels in bone by inhibition of 17β hydroxysteroid dehydrogenase type 2 (17β-HSD2) without affecting systemic E2 levels is an... 
DESIGN | CHEMISTRY, MEDICINAL | II 17-BETA-HYDROXYSTEROID-DEHYDROGENASE | LEAD OPTIMIZATION | BIOLOGICAL EVALUATION | IDENTIFICATION | TYPE-2 | DERIVATIVES | DISCOVERY | SOLUBILITY
Journal Article
Journal of Colloid And Interface Science, ISSN 0021-9797, 2010, Volume 349, Issue 2, pp. 583 - 593
Cu 2+ ion removal from aqueous streams by poly(acrylic acid-co-acrylamide) hydrogels is discussed. The monomer ratio has a significant effect on Cu 2+ removal.... 
XPS | Adsorption | Swelling | Hydrogels | ACID | BEHAVIOR | CHEMISTRY, PHYSICAL | COPPER | MODIFIED POLYACRYLAMIDE HYDROGELS | ACTIVATED CARBON | WASTE-WATER | SWELLING PROPERTIES | METAL-IONS | LEAD | Surface chemistry | Polymerization | Crosslinking | Monomers | X-ray photoelectron spectroscopy | Streams
Journal Article
Organic & biomolecular chemistry, ISSN 1477-0520, 02/2008, Volume 6, Issue 3, pp. 468 - 476
The copper complex of a chiral iminopyridine easily prepared from (R)-(-)-fenchone and picolylamine catalyzes the enantioselective Henry (nitroaldol) reaction... 
Copper - chemistry | Esters - chemistry | Methane - analogs & derivatives | Pyridines - chemistry | Stereoisomerism | Substrate Specificity | Ligands | Methane - chemistry | Nitroparaffins - chemistry | Catalysis
Journal Article
Tetrahedron: Asymmetry, ISSN 0957-4166, 2005, Volume 16, Issue 11, pp. 1953 - 1958
[Display omitted] Amides derived from ( S)-(+)-mandelic acid in the presence of titanium isopropoxide catalyze the enantioselective addition of dimethylzinc to... 
BETA-AMINO ALCOHOLS | ALKOXIDE-PROMOTED ADDITION | TITANIUM(IV) COMPLEXES | CHIRAL LIGANDS | HYDROXY CARBOXYLIC-ACIDS | DIALKYLZINC | ASYMMETRIC ORGANOZINC ADDITIONS | CHEMISTRY, PHYSICAL | AROMATIC-ALDEHYDES | DERIVATIVES | DIETHYLZINC ADDITIONS | Enantiomers
Journal Article
Synlett, ISSN 0936-5214, 06/2011, Volume 2011, Issue 9, pp. 1195 - 1211
Abstract This account shows our efforts towards the development of new N,N-ligands and their application in the asymmetric Henry reaction. Iminopyridine... 
account | N, N -ligands | nitro alcohols | asymmetric catalysis | nucleophilic additions | C symmetry | CATALYSIS | D-SOTALOL | ALPHA-HYDROXY ESTERS | BIS(OXAZOLINE) LIGANDS | INDUCED MYOCARDIAL INJURY | COMPLEXES | CHEMISTRY, ORGANIC | N,N-ligands | KETO ESTERS | ASYMMETRIC NITROALDOL REACTION | C-1-symmetry | STEREOSELECTIVE-SYNTHESIS | ALLYLIC SUBSTITUTIONS
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 09/2019, Volume 62, Issue 18, pp. 8443 - 8460
The emerging pharmacological target soluble epoxide hydrolase (sEH) is a bifunctional enzyme exhibiting two different catalytic activities that are located in... 
TARGET | CHEMISTRY, MEDICINAL | AGENTS | ACIDS | MODULATION | Index Medicus | Life Sciences | Biotechnology
Journal Article