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Diabetologia, ISSN 0012-186X, 4/2017, Volume 60, Issue 4, pp. 613 - 617
Journal Article
Nature Medicine, ISSN 1078-8956, 10/2011, Volume 17, Issue 10, pp. 1251 - 1260
Here we show that p38 mitogen-activated protein kinase (p38 MAPK) phosphorylates the spliced form of X-box binding protein 1 (Xbp1s) on its Thr48 and Ser61... 
MEDICINE, RESEARCH & EXPERIMENTAL | ER STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOPLASMIC-RETICULUM STRESS | CELL BIOLOGY | UNFOLDED PROTEIN RESPONSE | MESSENGER-RNA | INSULIN-RESISTANCE | GENE-EXPRESSION | PHOSPHOLIPID BIOSYNTHESIS | TRANSCRIPTION FACTOR | SIGNAL-TRANSDUCTION PATHWAY | TRANSMEMBRANE PROTEIN | Blood Glucose - physiology | Mitogen-Activated Protein Kinase Kinases - genetics | Phosphorylation | Active Transport, Cell Nucleus - physiology | Humans | MAP Kinase Kinase 3 - genetics | X-Box Binding Protein 1 | DNA-Binding Proteins - metabolism | MAP Kinase Kinase 6 - metabolism | Tandem Mass Spectrometry | MAP Kinase Kinase 6 - genetics | Chromatography, Liquid | Fibroblasts | Mitogen-Activated Protein Kinase 8 - genetics | p38 Mitogen-Activated Protein Kinases - metabolism | Liver - metabolism | Cells, Cultured | Obesity - physiopathology | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Gene Knockout Techniques | Mutation - genetics | Regulatory Factor X Transcription Factors | Obesity - metabolism | Transcription Factors - metabolism | Animals | Analysis of Variance | Homeostasis - physiology | Mice | Homeostasis | Physiological aspects | Glucose metabolism | Genetic aspects | Research | Mitogen-activated protein kinases | Proteins | Diabetes | Kinases | Binding sites | Index Medicus
Journal Article
Nature Medicine, ISSN 1078-8956, 10/2018, Volume 24, Issue 10, pp. 1526 - 1531
Trillions of microorganisms inhabit the human gut and are regarded as potential key factors for health(1,2). Characteristics such as diet, lifestyle, or... 
MEDICINE, RESEARCH & EXPERIMENTAL | DIET | GLUCOSE-METABOLISM | GENETICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DIVERSITY | HEALTH | AGE | CELL BIOLOGY | Genetics, Population | Africa - epidemiology | Clostridiales - classification | Humans | Netherlands - epidemiology | Risk Factors | Male | Gastrointestinal Microbiome - genetics | Bacteroides - genetics | Feces - microbiology | Ethnic Groups - genetics | Microbiota - genetics | Ethnic Groups - classification | Clostridiales - genetics | RNA, Ribosomal, 16S - genetics | Female | Clostridiales - isolation & purification | Bacteroides - classification | Bacteroides - isolation & purification | Ethnicity | Composition | Microbiota (Symbiotic organisms) | Demographic aspects | Urban population | Physiological aspects | Health aspects | Geography | rRNA 16S | Digestive system | Microbiomes | Ribonucleic acid--RNA | Minority & ethnic groups | Ethnic factors | Gene sequencing | Microorganisms | Microbiota | Diet | Intestine | Genetics | Intestinal microflora | Digestive tract | Index Medicus | Life Sciences | Santé publique et épidémiologie | Food and Nutrition | disease | Gastroenterologi | health | glucose-metabolism | enterotypes | Cell Biology | Medicine | Biochemistry & Molecular Biology | Research & Experimental | diversity | genetics | diet | markers | Gastroenterology and Hepatology | age
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2016, Volume 291, Issue 33, pp. 17394 - 17404
Journal Article
Journal of Hepatology, ISSN 0168-8278, 04/2019, Volume 70, Issue 1, pp. e304 - e304
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 08/2016, Volume 20, Issue 8, pp. 1561 - 1570
Journal Article
PLoS ONE, ISSN 1932-6203, 2017, Volume 12, Issue 11, pp. e0181693 - e0181693
An altered intestinal microbiota composition has been implicated in the pathogenesis of metabolic disease including obesity and type 2 diabetes mellitus... 
IMMUNITY | METABOLIC SYNDROME | BACTERIA | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | GASTROINTESTINAL-TRACT | FAT | LOW-GRADE INFLAMMATION | GUT MICROBIOTA | DIET-INDUCED OBESITY | RECEPTOR 5 | Inflammation - pathology | Gram-Negative Bacterial Infections - pathology | Intestines - pathology | Diabetes Mellitus, Type 2 - microbiology | Obesity - complications | Humans | Mice, Inbred C57BL | Glucose Intolerance - microbiology | Male | Obesity - microbiology | Glucose Intolerance - complications | Gram-Negative Bacterial Infections - microbiology | Feces - microbiology | Inflammation - complications | Animals | Intestines - microbiology | Ralstonia pickettii - physiology | Diet, High-Fat | Intra-Abdominal Fat - microbiology | DNA, Bacterial - analysis | Female | Aged | Intra-Abdominal Fat - pathology | Diabetes Mellitus, Type 2 - complications | Glucose intolerance | Microbiota (Symbiotic organisms) | Physiological aspects | Metabolic diseases | Development and progression | Research | Risk factors | Obesity | rRNA 16S | Adipose tissue | Pathogenesis | Diabetes mellitus | Ralstonia pickettii | Glucose | Insulin | Glucose tolerance | Intolerance | Microbiota | Intestine | Rodents | Insulin resistance | Bacteria | Mice | Intestinal microflora | Deoxyribonucleic acid--DNA | Teaching hospitals | Index Medicus | metabolic syndrome | receptor 5 | insulin-resistance | Endokrinologi och diabetes | bacteria | fat | low-grade inflammation | gastrointestinal-tract | immunity | diet-induced obesity | gut microbiota | Endocrinology and Diabetes | Microbiological Laboratory | Microbiologie | Microbiology | VLAG | WIMEK | Laboratorium voor Microbiologie | Deoxyribonucleic acid | DNA
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 01/2014, Volume 443, Issue 2, pp. 689 - 693
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2019, Volume 14, Issue 3, p. e0213202
Increasing evidence indicates that the development of type 2 diabetes is driven by chronic low grade beta-cell inflammation. However, it is unclear whether... 
Type 2 diabetes | Diabetics | Usage | PET imaging | Blood sugar | Analysis | Diagnosis | Health aspects
Journal Article
Cell, ISSN 0092-8674, 11/2016, Volume 167, Issue 4, p. 1052
It is widely believed that inflammation associated with obesity has an important role in the development of type 2 diabetes. I[kappa]B kinase beta (IKK[beta])... 
Type 2 diabetes | Medical colleges | Liver | Homeostasis | Insulin resistance | Cellular signal transduction | Inflammation | Glucose | Dextrose | Protein binding | Glucose metabolism | Insulin
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 01/2014, Volume 443, Issue 2, p. 689
acents Hyperactivation of mTORC1 due to loss of TSC1 induces glucose intolerance in vivo. acents IRS1.sup.Ser307 phosphorylation is not involved in... 
Glucose metabolism | Insulin resistance | Glucose | Dextrose
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2011, Volume 6, Issue 11, pp. e24564 - e24564
Journal Article