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Journal Article
Cancer Cell, ISSN 1535-6108, 05/2014, Volume 25, Issue 5, pp. 590 - 604
Journal Article
Cancer Cell, ISSN 1535-6108, 12/2014, Volume 26, Issue 6, pp. 909 - 922
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 09/2013, Volume 123, Issue 9, p. 3639
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 09/2013, Volume 123, Issue 9, pp. 3639 - 3639
Molecularly targeted agents promise to revolutionize therapeutics by reducing morbidity and mortality in patients with cancer. However, despite an urgent need... 
Journal Article
Frontiers in Oncology, ISSN 2234-943X, 2013, Volume 3, p. 86
Despite the ongoing "war on cancer," cancer remains one of the major causes of human morbidity and mortality. A new paradigm of targeted therapies holds the... 
Resistance | Targeted therapies | Activating somatic mutation | Lung cancer | Breast cancer | Reversible and irreversible tyrosine kinase inhibitors | ERBB2/HER2 | lung cancer | breast cancer | targeted therapies | resistance mechanisms | activating somatic mutation
Journal Article
Oncotarget, ISSN 1949-2553, 08/2018, Volume 9, Issue 60, pp. 31572 - 31589
CDK4 is emerging as a target in -mutant non-small cell lung cancer (NSCLC). We demonstrate that -mutant NSCLC cell lines are initially sensitive to the CDK4/6... 
MEK inhibitor | Drug resistance | CDK4/6 inhibitor | FGFR1 | KRAS-mutant non-small cell lung cancer
Journal Article
Journal Article
Cancer Discovery, ISSN 2159-8274, 02/2018, Volume 8, Issue 2, pp. 216 - 233
Journal Article
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 10/2018, Volume 24, Issue 19, pp. 4854 - 4864
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 10/2018, Volume 24, Issue 19, p. 4854
Despite the challenge to directly target mutant KRAS due to its high GTP affinity, some agents are under development against downstream signaling pathways,... 
Journal Article
18.