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Nature, ISSN 0028-0836, 10/2015, Volume 526, Issue 7575, pp. 700 - 704
Journal Article
Science, ISSN 0036-8075, 12/2018, Volume 362, Issue 6419, pp. 1165 - 1170
Journal Article
Genome Biology, ISSN 1474-7596, 06/2015, Volume 16, Issue 1, pp. 133 - 133
Journal Article
Cancer Letters, ISSN 0304-3835, 2015, Volume 371, Issue 1, pp. 79 - 89
Highlights • First mathematical model of a regulatory network of AURKA in neuroblastoma. • Model simulations uncover GWL/ MASTL stabilizing AURKA. • Role of... 
Hematology, Oncology and Palliative Medicine | Gene regulatory network | Neuroblastoma | Boolean network | GWL/MASTL | AURKA | ACTIVATION | AURORA-A KINASE | PROTEIN PHOSPHATASE 2A | MITOSIS | AMPLIFICATION | HELA-CELLS | ONCOLOGY | RISK NEUROBLASTOMA | SIGNALING NETWORK | MITOTIC SPINDLE | N-MYC | Oncogene Proteins - genetics | Microtubule-Associated Proteins - genetics | Oligonucleotide Array Sequence Analysis | Microtubule-Associated Proteins - metabolism | Humans | Neuroblastoma - enzymology | Gene Expression Regulation, Neoplastic | Child, Preschool | Databases, Genetic | Infant | Male | Neuroblastoma - mortality | Gene Regulatory Networks | Aurora Kinase A - metabolism | Young Adult | Computer Simulation | Female | N-Myc Proto-Oncogene Protein | Nuclear Proteins - genetics | Child | Aurora Kinase A - genetics | Infant, Newborn | Neuroblastoma - pathology | Protein-Serine-Threonine Kinases - metabolism | Signal Transduction | Neuroblastoma - genetics | Enzyme Stability | Oncogene Proteins - metabolism | Protein Phosphatase 2 - genetics | Protein-Serine-Threonine Kinases - genetics | Gene Expression Profiling - methods | Nuclear Proteins - metabolism | Gene Expression Regulation, Enzymologic | Adolescent | Protein Phosphatase 2 - metabolism | Survival Analysis | Models, Genetic | Analysis | Models | Proteins | Medical research | Genes | Medical prognosis | Cell cycle | Kinases | Phosphatase | Cell adhesion & migration
Journal Article
Cancer Cell, ISSN 1535-6108, 11/2014, Volume 26, Issue 5, pp. 722 - 737
Journal Article
Cancer Cell, ISSN 1535-6108, 03/2018, Volume 33, Issue 3, pp. 417 - 434.e7
Journal Article
Molecular Oncology, ISSN 1574-7891, 02/2016, Volume 10, Issue 2, pp. 344 - 359
Neuroblastoma is an embryonal pediatric tumor that originates from the developing sympathetic nervous system and shows a broad range of clinical behavior,... 
TFAP2B | Neuroblastoma | Differentiation | Retinoic acid | Prognostic marker | TUMOR-SUPPRESSOR GENES | 13-CIS-RETINOIC ACID | MONOCLONAL-ANTIBODY | FACTOR AP-2 | BREAST-CANCER | ONCOLOGY | POOR-PROGNOSIS | RANK STATISTICS | HIGH-RISK NEUROBLASTOMA | FACTOR AP-2-BETA | Tyrosine 3-Monooxygenase - metabolism | Up-Regulation | Adrenergic Neurons - metabolism | Prognosis | Humans | Child, Preschool | Infant | Transcription Factor AP-2 - metabolism | Gene Knockdown Techniques | Young Adult | Adrenergic Neurons - pathology | Dopamine beta-Hydroxylase - metabolism | Adult | N-Myc Proto-Oncogene Protein | Child | Infant, Newborn | Neuroblastoma - pathology | Repressor Proteins - metabolism | Tretinoin - pharmacology | Promoter Regions, Genetic | Down-Regulation | Neuroblastoma - genetics | Oncogene Proteins - metabolism | Azacitidine - analogs & derivatives | Nuclear Proteins - metabolism | Azacitidine - pharmacology | Transcription Factor AP-2 - genetics | Cell Cycle | Cell Differentiation - drug effects | Adolescent | Cell Line, Tumor | CpG Islands - genetics | Neuroblastoma - metabolism | DNA Methylation - drug effects | RNA, Small Interfering - metabolism | Enzymes | DNA microarrays | Neurons | Analysis | Oncology, Experimental | Genes | Genetic research | Physiological aspects | Research | Methylation | Cancer | Cell proliferation | Pediatrics | Transcription factors | Nervous system | Neuroblastoma cells | Proteins | Demethylation | Cell cycle | DNA methylation | Age | Deoxyribonucleic acid--DNA | CpG islands | AP-2 protein | Grants | Cell differentiation | Gene expression | Sympathetic nervous system | Patients | Esophagus | Molecular modelling | Biomarkers | Norepinephrine | Tumors
Journal Article
Cancer Research, ISSN 0008-5472, 06/2007, Volume 67, Issue 12, pp. 5727 - 5736
Journal Article