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Journal of biological rhythms, ISSN 0748-7304, 2/2018, Volume 33, Issue 1, pp. 84 - 98
Modern imaging techniques allow the monitoring of circadian rhythms of single cells. Coupling between these single cellular circadian oscillators can generate... 
Oscillator | Suprachiasmatic Nucleus | Coupling | Synchronization | Circadian Clock
Journal Article
Cell Metabolism, ISSN 1550-4131, 09/2013, Volume 18, Issue 3, pp. 416 - 430
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2009, Volume 106, Issue 50, pp. 21407 - 21412
Journal Article
Current Biology, ISSN 0960-9822, 04/2015, Volume 25, Issue 8, pp. R337 - R339
Using real-time imaging of circadian gene expression, a new study reveals how a light pulse briefly desynchronizes clock neurons in the fly brain before they... 
ORGANIZATION | NETWORK | SUPRACHIASMATIC NUCLEUS | SYNCHRONY | BIOCHEMISTRY & MOLECULAR BIOLOGY | DROSOPHILA | CELL BIOLOGY | Animals | Period Circadian Proteins - metabolism | Light | Circadian Rhythm - physiology | Neurons - metabolism | Circadian Clocks - physiology | Nerve Net - physiology | Index Medicus
Journal Article
Journal Article
Journal Article
Journal of Biological Rhythms, ISSN 0748-7304, 10/2015, Volume 30, Issue 5, pp. 396 - 407
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2009, Volume 106, Issue 38, pp. 16493 - 16498
Circadian rhythms are modeled as reliable and self-sustained oscillations generated by single cells. The mammalian suprachiasmatic nucleus (SCN) keeps near... 
Suprachiasmatic nucleus | Cell culture techniques | Bioluminescence | Neurons | Cultured cells | Neuropeptides | Circadian rhythm | Gene expression | Current density | Oscillators | Pacemaker | Period gene | Luciferase | Vasoactive intestinal polypeptide | CLOCK GENE-EXPRESSION | pacemaker | BRAIN CLOCK | MULTIDISCIPLINARY SCIENCES | RAT SUPRACHIASMATIC NUCLEUS | NETWORK MODEL | INDIVIDUAL FIBROBLASTS | SYNCHRONIZATION | OSCILLATORS | PERIOD | luciferase | suprachiasmatic nucleus | CELL | vasoactive intestinal polypeptide | SCN | Immunohistochemistry | Vasoactive Intestinal Peptide - metabolism | Luciferases - metabolism | Neurons - cytology | Luciferases - genetics | Suprachiasmatic Nucleus - physiology | Neurons - physiology | Suprachiasmatic Nucleus - cytology | Cell Cycle Proteins - genetics | Suprachiasmatic Nucleus - metabolism | Neurons - metabolism | Nuclear Proteins - genetics | Tissue Culture Techniques | Mice, Inbred C57BL | Cell Cycle Proteins - metabolism | Cells, Cultured | Nuclear Proteins - metabolism | Circadian Rhythm - physiology | Transcription Factors - genetics | Luminescent Measurements - methods | Period Circadian Proteins | Gene Knock-In Techniques | Transcription Factors - metabolism | Patch-Clamp Techniques | Animals | Arginine Vasopressin - metabolism | Mice | Proteins | Cell culture | Signal transduction | Peptides | Index Medicus | Biological Sciences
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2013, Volume 123, Issue 12, pp. 5389 - 5400
Brain aging is associated with diminished circadian clock output and decreased expression of the core clock proteins, which regulate many aspects of cellular... 
MEDICINE, RESEARCH & EXPERIMENTAL | NERVOUS-SYSTEM | CYCLOOXYGENASE-2 | RHYTHMS | IN-VIVO | ADAPTATION | GENE-EXPRESSION | COMPONENTS | BMAL1 | BRAIN | NPAS2 | Neurons - pathology | Oxidative Stress | Neuroglia - pathology | Nerve Tissue Proteins - deficiency | Cerebral Cortex - pathology | Nerve Degeneration - physiopathology | Nerve Degeneration - genetics | Period Circadian Proteins - deficiency | CLOCK Proteins - deficiency | Mice, Neurologic Mutants | Gliosis - pathology | ARNTL Transcription Factors - deficiency | RNA Interference | Neurons - metabolism | Corpus Striatum - pathology | Basic Helix-Loop-Helix Transcription Factors - deficiency | Period Circadian Proteins - physiology | Basic Helix-Loop-Helix Transcription Factors - physiology | CLOCK Proteins - physiology | Gliosis - genetics | Nerve Tissue Proteins - physiology | Oxidation-Reduction | Brain - physiopathology | Mice, Inbred C57BL | Circadian Rhythm - genetics | Gene Expression Regulation - physiology | Circadian Rhythm - physiology | Hippocampus - pathology | Mice, Knockout | Animals | Aging - physiology | Homeostasis - physiology | Brain - pathology | Sleep Disorders, Circadian Rhythm - physiopathology | Neuroglia - metabolism | Locomotion - physiology | ARNTL Transcription Factors - physiology | Homeostasis - genetics | Circadian rhythms | Physiological aspects | Homeostasis | Nervous system | Degeneration | Research | Brain | Oxidative stress | Neurodegeneration | Rodents | Circadian rhythm | Behavior | Kinases | Gene expression | Age | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 07/2010, Volume 30, Issue 30, pp. 10220 - 10232
Diet restriction retards aging and extends lifespan by triggering adaptive mechanisms that alter behavioral, physiological, and biochemical responses in... 
LIFE-SPAN EXTENSION | ENERGY-BALANCE | STIMULATED INSULIN-SECRETION | CAENORHABDITIS-ELEGANS | C-FOS | FOOD-ANTICIPATORY ACTIVITY | MICE | SACCHAROMYCES-CEREVISIAE | NEUROSCIENCES | INCREASED DOSAGE | CALORIE RESTRICTION | Enzyme-Linked Immunosorbent Assay - methods | Sirtuin 1 - metabolism | Receptors, G-Protein-Coupled - metabolism | Body Temperature - drug effects | Adaptation, Physiological - drug effects | Dorsomedial Hypothalamic Nucleus - physiology | Hypothalamic Area, Lateral - cytology | Motor Activity - drug effects | Male | Receptors, Neuropeptide - metabolism | RNA, Messenger - metabolism | Sirtuin 1 - genetics | Brain - metabolism | Hypothalamic Area, Lateral - physiology | Statistics, Nonparametric | Chromatin Immunoprecipitation - methods | Female | Neurons - metabolism | Sirtuin 1 - deficiency | Neurons - drug effects | Dorsomedial Hypothalamic Nucleus - drug effects | Dorsomedial Hypothalamic Nucleus - cytology | Mice, Inbred C57BL | Adaptation, Physiological - physiology | Receptors, Neuropeptide - genetics | Ghrelin - pharmacology | Up-Regulation - genetics | Orexin Receptors | Food Deprivation - physiology | Motor Activity - genetics | Ghrelin - blood | Microdissection - methods | Animals | Body Temperature - genetics | Hypothalamic Area, Lateral - drug effects | Mice | Receptors, G-Protein-Coupled - genetics | Index Medicus | diet restriction | SIRT1 | hypothalamus | DMH | orexin type 2 receptor
Journal Article