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by Mok, Tony S K and Wu, Yi-Long and Kudaba, Iveta and Kowalski, Dariusz M and Cho, Byoung Chul and Turna, Hande Z and Castro, Gilberto and Srimuninnimit, Vichien and Laktionov, Konstantin K and Bondarenko, Igor and Kubota, Kaoru and Lubiniecki, Gregory M and Zhang, Jin and Kush, Debra and Lopes, Gilberto and Adamchuk, Grigory and Ahn, Myung-Ju and Alexandru, Aurelia and Altundag, Ozden and Alyasova, Anna and Andrusenko, Orest and Aoe, Keisuke and Araujo, Antonio and Aren, Osvaldo and Arrieta Rodriguez, Oscar and Ativitavas, Touch and Avendano, Oscar and Barata, Fernando and Barrios, Carlos Henrique and Beato, Carlos and Bergstrom, Per and Betticher, Daniel and Bolotina, Larisa and Bondarenko, Igor and Botha, Michiel and Buddu, Sayeuri and Caglevic, Christian and Cardona, Andres and Castro, Gilberto and Castro, Hugo and Cay Senler, Filiz and Cerny, Carlos Alexandre Sydow and Cesas, Alvydas and Chan, Gee-Chen and Chang, Jianhua and Chen, Gongyan and Chen, Xi and Cheng, Susanna and Cheng, Ying and Cherciu, Nelly and Chiu, Chao-Hua and Cho, Byoung Chul and Cicenas, Saulius and Ciurescu, Daniel and Cohen, Graham and Costa, Marcos Andre and Danchaivijitr, Pongwut and De Angelis, Flavia and de Azevedo, Sergio Jobim and Dediu, Mircea and Deliverski, Tsvetan and De Marchi, Pedro Rafael Martins and de The Bustamante Valles, Flor and Ding, Zhenyu and Doganov, Boyan and Dreosti, Lydia and Duarte, Ricardo and Edusma-Dy, Regina and Emelyanov, Sergey and Erman, Mustafa and Fan, Yun and Fein, Luis and Feng, Jifeng and Fenton, David and Fernandes, Gustavo and Ferreira, Carlos and Franke, Fabio Andre and Freitas, Helano and Fujisaka, Yasuhito and Galindo, Hector and Galvez, Christina and Ganea, Doina and Gil, Nuno and Girotto, Gustavo and Goker, Erdem and Goksel, Tuncay and Gomez Aubin, Gonzalo and Gomez Wolff, Luis and Griph, Hakan and Gumus, Mahmut and Hall, Jacqueline and Hart, Gregory and Havel, Libor and He, Jianxing and He, Yong and Hernandez Hernandez, Carlos and Hespanhol, Venceslau and Hirashima, Tomonori and Ho, Chung Man James and Horiike, Atsushi and ... and KEYNOTE-042 Investigators
The Lancet, ISSN 0140-6736, 05/2019, Volume 393, Issue 10183, pp. 1819 - 1830
First-line pembrolizumab monotherapy improves overall and progression-free survival in patients with untreated metastatic non-small-cell lung cancer with a... 
MEDICINE, GENERAL & INTERNAL | CARBOPLATIN | GEFITINIB | BEVACIZUMAB | CRIZOTINIB | NIVOLUMAB | PACLITAXEL | Genes, erbB-1 - drug effects | Lung Neoplasms - drug therapy | Translocation, Genetic | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Humans | Lung Neoplasms - metabolism | Middle Aged | Far East - epidemiology | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Lung Neoplasms - pathology | Male | Anaplastic Lymphoma Kinase - genetics | Antibodies, Monoclonal, Humanized - administration & dosage | Carcinoma, Non-Small-Cell Lung - secondary | Lung Neoplasms - secondary | Female | Carcinoma, Non-Small-Cell Lung - pathology | Anaplastic Lymphoma Kinase - drug effects | Antibodies, Monoclonal, Humanized - adverse effects | Antibodies, Monoclonal, Humanized - therapeutic use | Drug Administration Schedule | Genes, erbB-1 - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Disease-Free Survival | B7-H1 Antigen - metabolism | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Neoplasm Metastasis - pathology | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Mutation | Chemotherapy | Metastasis | Lung cancer, Non-small cell | Cancer | Lung cancer | Oncology | Kinases | Cancer therapies | Evidence-based medicine | Metastases | Pembrolizumab | Randomization | Motivation | Platinum | Risk assessment | Population | Translocation | Cell survival | Life expectancy | Epidermal growth factor receptors | Hyperthyroidism | Histology | Health care facilities | Hypothyroidism | Survival | Patients | Life span | Interactive systems | PD-L1 protein | Men | Ligands | Tumors | Apoptosis
Journal Article
Journal of Thoracic and Cardiovascular Surgery, The, ISSN 0022-5223, 2013, Volume 145, Issue 4, pp. 926 - 932
Journal Article
Future Oncology, ISSN 1479-6694, 03/2018, Volume 14, Issue 6, pp. 567 - 575
The global burden of lung cancer has been increasing over the past years, and is still a major threat to public health worldwide, leading to disabilities and... 
epidemiology | lung cancer screening | biomarkers | low-dose computed tomography | smoking | MORTALITY | MANAGEMENT | STAGE | FAMILIAL RISK | TRIAL | CHEST RADIOGRAPH | ONCOLOGY | SPIRAL COMPUTED-TOMOGRAPHY | EXPOSURE | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2013, Volume 8, Issue 9, p. e72373
Introduction: Polymorphic variants in the 5p15, 6p12, 6p21, and 15q25 loci were demonstrated to potentially contribute to lung cancer carcinogenesis.... 
PHASE-III TRIAL | SURVIVAL | GENE | BEVACIZUMAB | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY | 1ST-LINE THERAPY | FACTOR RECEPTOR | GEMCITABINE | ENDOTHELIAL GROWTH-FACTOR | GENOME-WIDE ASSOCIATION | Multivariate Analysis | Prognosis | Prospective Studies | Lung Neoplasms - mortality | Humans | Middle Aged | Lung Neoplasms - pathology | Male | Genetic Loci | Vascular Endothelial Growth Factor A - genetics | Portugal | Case-Control Studies | Aged, 80 and over | Adult | Female | Chromosomes, Human, Pair 5 - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Genetic Predisposition to Disease | Genetic Association Studies | Carcinoma, Non-Small-Cell Lung - genetics | Risk Factors | Kaplan-Meier Estimate | Chromosomes, Human, Pair 15 - genetics | Carcinoma, Non-Small-Cell Lung - mortality | Chromosomes, Human, Pair 6 - genetics | Disease-Free Survival | Aged | Polymorphism, Single Nucleotide | Oncology, Experimental | Genomics | Lung cancer, Small cell | Development and progression | Research | Lung cancer, Non-small cell | Vascular endothelial growth factor | Cancer | Health sciences | Disease | Laboratories | Lung cancer | Oncology | Risk | Genomes | Single-nucleotide polymorphism | Carcinogenesis | Angiogenesis | Carcinogens | Epidermal growth factor | Chromosome 15 | Deoxyribonucleic acid--DNA | Health risks | Non-small cell lung carcinoma | Chromosome 6 | Histology | Chromosome 5 | Medical screening | Survival | Patients | Loci | Medicine | Studies | Hospitals | Medical prognosis | Biomarkers | Mutation | Deoxyribonucleic acid | DNA
Journal Article
Journal of Thoracic Oncology, ISSN 1556-0864, 01/2017, Volume 12, Issue 1, pp. S274 - S275
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 488 - 488
Tumor-specific (somatic) mutations in plasma can serve as biomarkers for tumor detection, monitor tumor response to specific therapies, detect residual disease... 
Journal Article
CANCERS, ISSN 2072-6694, 09/2019, Volume 11, Issue 9, p. 1229
Identification of targetable molecular changes is essential for selecting appropriate treatment in patients with advanced lung adenocarcinoma. Methods: In this... 
CANCER PATIENTS | targeted therapy | KINASE INHIBITORS GUIDELINE | NSCLC | next-generation sequencing | MOLECULAR TESTING GUIDELINE | CLASSIFICATION | EGFR | lung cancer | ONCOLOGY | MUTATION | INTERNATIONAL-ASSOCIATION | OF-AMERICAN-PATHOLOGISTS | KRAS | molecular profiling
Journal Article
Journal Article
JOURNAL OF CLINICAL MEDICINE, ISSN 2077-0383, 03/2019, Volume 8, Issue 3, p. 315
Background: Few data are available on chronic bacterial infections (CBI) in bronchiectasis patients. Given that CBI seems to trigger longer hospital stays,... 
ADULT PATIENTS | DIAGNOSIS | MEDICINE, GENERAL & INTERNAL | chronic bacterial infection | PSEUDOMONAS-AERUGINOSA | INFLAMMATION | Pseudomonas aeruginosa | COLONIZATION | CYSTIC-FIBROSIS | bronchiectasis
Journal Article
Scientific reports, ISSN 2045-2322, 02/2020, Volume 10, Issue 1, pp. 3625 - 9
EGFR and KRAS are the most frequently mutated genes in lung cancer, being active research topics in targeted therapy. The biopsy is the traditional method to... 
Phenotypes | Epidermal growth factor receptors | Computed tomography | Biopsy | Lung cancer | Biomarkers | Mutation | Tumors
Journal Article
Journal of Thoracic Oncology, ISSN 1556-0864, 01/2017, Volume 12, Issue 1, pp. S950 - S950
Journal Article
Tumor Biology, ISSN 1010-4283, 12/2012, Volume 33, Issue 6, pp. 2061 - 2068
Journal Article
Journal of Cardiopulmonary Rehabilitation and Prevention, ISSN 1932-7501, 09/2012, Volume 32, Issue 5, pp. 278 - 283
Journal Article
Archives of Bronchology (Archivos de Bronconeumología, English Edition), ISSN 1579-2129, 2016, Volume 53, Issue 9, pp. 530 - 531
Journal Article
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