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1. Editorial [Hot topic: Emerging roles of the unfolded protein response signaling in physiology and disease (executive editor: Claudio A. Hetz and Claudio Soto)]
by Hetz, Claudio A and Soto, Claudio
Current Molecular Medicine, ISSN 1566-5240, 02/2006, Volume 6, Issue 1, pp. 1 - 3
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2. Full Text The unfolded protein response: Controlling cell fate decisions under ER stress and beyond
by Hetz, Claudio
Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 02/2012, Volume 13, Issue 2, pp. 89 - 102
Protein-folding stress at the endoplasmic reticulum (ER) is a salient feature of specialized secretory cells and is also involved in the pathogenesis of many... 
NF-Y | ACTIVATION | MESSENGER-RNA | LUMINAL DOMAIN | IRE1 | BAX INHIBITOR-1 | ENDOPLASMIC-RETICULUM STRESS | TRANSCRIPTION FACTOR ATF6 | TRANSMEMBRANE PROTEIN | NEGATIVE REGULATOR | CELL BIOLOGY | Cell Proliferation | Unfolded Protein Response - genetics | Adaptation, Biological - genetics | Humans | Cell Survival - genetics | Apoptosis - genetics | Endoplasmic Reticulum Stress - genetics | Adaptation, Biological - physiology | Cell Differentiation - genetics | Animals | Cell Death - genetics | Cell Death - physiology | Apoptosis - physiology | Cell Differentiation - physiology | Unfolded Protein Response - physiology | Cell Survival - physiology | Endoplasmic Reticulum Stress - physiology
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3. Full Text Guidelines for the use and interpretation of assays for monitoring autophagy
by Klionsky, Daniel J and Abdalla, Fabio C and Abeliovich, Hagai and Abraham, Robert T and Acevedo-Arozena, Abraham and Adeli, Khosrow and Agholme, Lotta and Agnello, Maria and Agostinis, Patrizia and Aguirre-Ghiso, Julio A and Ahn, Hyung Jun and Ait-Mohamed, Ouardia and Ait-Si-Ali, Slimane and Akematsu, Takahiko and Akira, Shizuo and Al-Younes, Hesham M and Al-Zeer, Munir A and Albert, Matthew L and Albin, Roger L and Alegre-Abarrategui, Javier and Aleo, Maria Francesca and Alirezaei, Mehrdad and Almasan, Alexandru and Almonte-Becerril, Maylin and Amano, Atsuo and Amaravadi, Ravi K and Amarnath, Shoba and Amer, Amal O and Andrieu-Abadie, Nathalie and Anantharam, Vellareddy and Ann, David K and Anoopkumar-Dukie, Shailendra and Aoki, Hiroshi and Apostolova, Nadezda and Arancia, Giuseppe and Aris, John P and Asanuma, Katsuhiko and Asare, Nana Y.O and Ashida, Hisashi and Askanas, Valerie and Askew, David S and Auberger, Patrick and Baba, Misuzu and Backues, Steven K and Baehrecke, Eric H and Bahr, Ben A and Bai, Xue-Yuan and Bailly, Yannick and Baiocchi, Robert and Baldini, Giulia and Balduini, Walter and Ballabio, Andrea and Bamber, Bruce A and Bampton, Edward T.W and Juhász, Gábor and Bartholomew, Clinton R and Bassham, Diane C and Bast, Robert C and Batoko, Henri and Bay, Boon-Huat and Beau, Isabelle and Béchet, Daniel M and Begley, Thomas J and Behl, Christian and Behrends, Christian and Bekri, Soumeya and Bellaire, Bryan and Bendall, Linda J and Benetti, Luca and Berliocchi, Laura and Bernardi, Henri and Bernassola, Francesca and Besteiro, Sébastien and Bhatia-Kissova, Ingrid and Bi, Xiaoning and Biard-Piechaczyk, Martine and Blum, Janice S and Boise, Lawrence H and Bonaldo, Paolo and Boone, David L and Bornhauser, Beat C and Bortoluci, Karina R and Bossis, Ioannis and Bost, Frédéric and Bourquin, Jean-Pierre and Boya, Patricia and Boyer-Guittaut, Michaël and Bozhkov, Peter V and Brady, Nathan R and Brancolini, Claudio and Brech, Andreas and Brenman, Jay E and Brennand, Ana and Bresnick, Emery H and Brest, Patrick and Bridges, Dave and Bristol, Molly L and Brookes, Paul S and Brown, Eric J and Brumell, John H and ... and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Geriatrik and Institutionen för medicin och hälsa and Farmakologi and Experimentell patologi and Hälsouniversitetet and Cellbiologi
Autophagy, ISSN 1554-8627, 04/2012, Volume 8, Issue 4, pp. 445 - 544
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and... 
stress | vacuole | autolysosome | flux | LC3 | autophagosome | lysosome | phagophore | Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | Phagophore | Lysosome | Autolysosome | Flux | Autophagosome | Vacuole | Stress | ACTIVATED PROTEIN-KINASE | CHAPERONE-MEDIATED AUTOPHAGY | VACUOLE TARGETING PATHWAY | ENDOPLASMIC-RETICULUM STRESS | ISOLATED RAT HEPATOCYTES | STARVATION-INDUCED AUTOPHAGY | GLUCAGON-INDUCED AUTOPHAGY | CELL BIOLOGY | PROGRAMMED CELL-DEATH | BREAST-CANCER CELLS | BETAINE HOMOCYSTEINE METHYLTRANSFERASE | Biological Assay - methods | Animals | Autophagy - genetics | Models, Biological | Humans | Life Sciences | Cellular Biology | Review | Medical and Health Sciences | Medicin och hälsovetenskap
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4. BCL-2 protein family
: essential regulators of cell death
by Hetz, Claudio
2010, Advances in experimental medicine and biology, ISBN 1441967052, Volume 687., xvii, 145
This book highlights the relevance of the BCL‑2 family of proteins in apoptosis, physiology and disease. It examines the potential therapeutic benefits of... 
pathology | physiology | metabolism | Proto-Oncogene Proteins c-bcl-2 | Tumor proteins | Neoplasms | Apoptosis
Book
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5. Full Text Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases
by Hetz, Claudio and Mollereau, Bertrand
Nature Reviews Neuroscience, ISSN 1471-003X, 2014, Volume 15, Issue 4, pp. 233 - 249
The unfolded protein response (UPR) is a homeostatic mechanism by which cells regulate levels of misfolded proteins in the endoplasmic reticulum (ER). Although... 
SYNUCLEINOPATHY IN-VIVO | UNFOLDED-PROTEIN RESPONSE | IMPROVES FUNCTIONAL RECOVERY | TRANSCRIPTION FACTOR XBP-1 | SODIUM 4-PHENYLBUTYRATE PROTECTS | SPINAL-CORD-INJURY | GAMMA-SECRETASE ACTIVITY | AMYOTROPHIC-LATERAL-SCLEROSIS | AMYLOID PRECURSOR PROTEIN | LYSOSOMAL STORAGE DISORDERS | NEUROSCIENCES | Stress, Physiological - physiology | Animals | Neurodegenerative Diseases - physiopathology | Homeostasis - physiology | Humans | Endoplasmic Reticulum - physiology | Unfolded Protein Response - physiology | Protein research | Protein metabolism | Physiological aspects | Nervous system | Degeneration | Research | Neurological research | Endoplasmic reticulum | Life Sciences
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6. Full Text ER stress and the unfolded protein response in neurodegeneration
by Hetz, Claudio and Saxena, Smita
Nature Reviews Neurology, ISSN 1759-4758, 08/2017, Volume 13, Issue 8, pp. 477 - 491
The clinical manifestation of neurodegenerative diseases is initiated by the selective alteration in the functionality of distinct neuronal populations. The... 
MOTOR-NEURONS | DISULFIDE-ISOMERASE | ALZHEIMERS-DISEASE | MOUSE MODEL | IMPROVES FUNCTIONAL RECOVERY | SODIUM 4-PHENYLBUTYRATE PROTECTS | SPINAL-CORD | ENDOPLASMIC-RETICULUM STRESS | AMYOTROPHIC-LATERAL-SCLEROSIS | ALPHA-SYNUCLEIN | CLINICAL NEUROLOGY | Inflammation - metabolism | Animals | Signal Transduction | Neuronal Plasticity | Endoplasmic Reticulum Stress | Humans | Neurodegenerative Diseases - metabolism | Unfolded Protein Response | Nerve Degeneration - metabolism | Care and treatment | Analysis | Quality control | Nervous system | Degeneration | Research | Endoplasmic reticulum | Neurodegeneration | Protein folding
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7. Stressing out the ER: A role of the unfolded protein response in prion-related disorders
by Hetz, Claudio A and Soto, Claudio
Current Molecular Medicine, ISSN 1566-5240, 02/2006, Volume 6, Issue 1, pp. 37 - 43
Glucose-regulated proteins | Aggresomes | Caspase-12 | lke | ER stress | Prion related disorders | Apoptosis | Proteasome | PrP
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