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1. Full Text Anomalous Diffusion of Single Particles in Cytoplasm
by Regner, Benjamin M and Vučinić, Dejan and Domnisoru, Cristina and Bartol, Thomas M and Hetzer, Martin W and Tartakovsky, Daniel M and Sejnowski, Terrence J
Biophysical Journal, ISSN 0006-3495, 04/2013, Volume 104, Issue 8, pp. 1652 - 1660
The crowded intracellular environment poses a formidable challenge to experimental and theoretical analyses of intracellular transport mechanisms. Our... 
CELLS | FRACTIONAL DYNAMICS | BIOPHYSICS | INTRACELLULAR-TRANSPORT | PERSPECTIVE | MEMBRANE | RESOLUTION | MEDIA | HIGH-SPEED | PROTEINS | MICROSCOPY | Xenopus | Microspheres | Motion | Biological Transport, Active | Microtubules - metabolism | Animals | Models, Biological | Cytoplasm - metabolism | Diffusion | Sects | Neurosciences | Analysis | Cells | Aerospace engineering | Cell Biophysics
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2. Full Text Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects
by Mertens, Jerome and Paquola, Apuã C.M and Ku, Manching and Hatch, Emily and Böhnke, Lena and Ladjevardi, Shauheen and McGrath, Sean and Campbell, Benjamin and Lee, Hyungjun and Herdy, Joseph R and Gonçalves, J. Tiago and Toda, Tomohisa and Kim, Yongsung and Winkler, Jürgen and Yao, Jun and Hetzer, Martin W and Gage, Fred H
Cell Stem Cell, ISSN 1934-5909, 12/2015, Volume 17, Issue 6, pp. 705 - 718
Aging is a major risk factor for many human diseases, and in vitro generation of human neurons is an attractive approach for modeling aging-related brain... 
PLURIPOTENT STEM-CELLS | REJUVENATION | CONVERSION | DNA-DAMAGE | DISEASE | HUMAN FIBROBLASTS | GENE-REGULATION | PROGERIA | IDENTIFICATION | HIGHLY EFFICIENT | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Cell Separation | Humans | Middle Aged | Transcriptome | Child, Preschool | Cytoplasm - metabolism | Infant | Neurons - cytology | ran GTP-Binding Protein - metabolism | Cellular Reprogramming | Young Adult | Cell Nucleus - metabolism | Flow Cytometry | Adolescent | Neural Cell Adhesion Molecules - metabolism | Aged, 80 and over | Aging | Adult | Aged | Fibroblasts - cytology | Induced Pluripotent Stem Cells - cytology | Child | Infant, Newborn
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3. Full Text Epidemiology and clinical profile of pathogens responsible for the hospitalization of children in Sousse area, Tunisia
by Brini, Ines and Guerrero, Aida and Hannachi, Naila and Bouguila, Jihene and Orth-Höller, Dorothea and Bouhlel, Amira and Boughamoura, Lamia and Hetzer, Benjamin and Borena, Wegene and Schiela, Britta and Von Laer, Dorothee and Boukadida, Jalel and Stoiber, Heribert
PLoS ONE, ISSN 1932-6203, 11/2017, Volume 12, Issue 11, p. e0188325
This study aimed to identify a broad spectrum of respiratory pathogens from hospitalized and not-preselected children with acute respiratory tract infections... 
ETIOLOGY | STREPTOCOCCUS-PNEUMONIAE | UNIT | MULTIDISCIPLINARY SCIENCES | HUMAN METAPNEUMOVIRUS | INFANTS | RESPIRATORY-SYNCYTIAL-VIRUS | ASSAYS | TRACT INFECTIONS | PCR | FEATURES | Respiratory tract infections | Pathogenic microorganisms | Demographic aspects | Distribution | Causes of | Genetic aspects | Research | Multiplexing | Pathogens | rRNA 16S | Statistical analysis | C-reactive protein | Gastroenteritis | Bronchopneumonia | Viruses | Infections | Statistical methods | Real time | Epidemiology | Laryngitis | Polymerase chain reaction | Respiratory tract | Demographics | Respiratory syncytial virus | Streptococcus | Samples | Respiratory tract diseases | Children | Parainfluenza | Viral infections | Deoxyribonucleic acid--DNA | Deoxyribonucleic acid | DNA
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4. Full Text Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy
by Grimmler, Matthias and Hassel, David and Huge, Andreas and Dahme, Tillman and Meder, Benjamin and Regitz-Zagrosek, Vera and Weichenhan, Dieter and Erdmann, Jeanette and Liptau, Henrike and Hess, Alexander and Just, Steffen and Ehlermann, Philipp and Hetzer, Roland and Fischer, Christine and Stoll, Monika and Nürnberg, Peter and Rottbauer, Wolfgang and Schunkert, Heribert and Katus, Hugo A
Nature Medicine, ISSN 1078-8956, 11/2009, Volume 15, Issue 11, pp. 1281 - 1288
Z-disks, the mechanical integration sites of heart and skeletal muscle cells, link anchorage of myofilaments to force reception and processing. The key... 
MEDICINE, RESEARCH & EXPERIMENTAL | GENETIC-BASIS | ZEBRAFISH | PROTEIN | CONTRACTILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHENOTYPES | CELL BIOLOGY | HEART | HYPERTROPHIC CARDIOMYOPATHY | MECHANICAL STRETCH SENSOR | DISEASE | COMPONENT | Cardiomyopathy, Dilated - pathology | Embryo, Mammalian | Muscle Contraction - genetics | Humans | Middle Aged | Family Health | Male | Chromosomes, Human, Pair 1 | Sarcomeres - genetics | Adult | Female | Sarcomeres - physiology | Microfilament Proteins - genetics | Disease Models, Animal | Cardiomyopathy, Dilated - genetics | Amino Acid Sequence | Genetic Predisposition to Disease - genetics | Microfilament Proteins - deficiency | Animals, Genetically Modified | Computational Biology | Myocardium - pathology | Zebrafish | Mutation - genetics | Myocytes, Cardiac - pathology | Animals | Cardiomyopathy, Dilated - etiology | Muscle Fibers, Skeletal | Chromosome Aberrations | Myocytes, Cardiac - metabolism | Polymorphism, Single Nucleotide - genetics | Aged | Gene mutations | Cardiomyopathy | Analysis | Medical genetics | Development and progression | Genetic aspects | Research | Striated muscle | Properties | Molecular biology | Heart diseases | Medical research | Mutation | Cellular biology | Cardiology
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5. Full Text Vedolizumab use after failure of TNF-α antagonists in children and adolescents with inflammatory bowel disease
by Schneider, Anna-Maria and Weghuber, Daniel and Hetzer, Benjamin and Entenmann, Andreas and Müller, Thomas and Zimmermann, Georg and Schütz, Sebastian and Huber, Wolf-Dietrich and Pichler, Judith
BMC Gastroenterology, ISSN 1471-230X, 09/2018, Volume 18, Issue 1, pp. 140 - 7
Background: Vedolizumab is safe and effective in adult patients with Crohn's disease (CD) and ulcerative colitis (UC); however, data in children with... 
Crohn's disease | Integrin antagonist | Paediatrics | Ulcerative colitis | PEDIATRIC CROHNS-DISEASE | MODERATE | METAANALYSIS | EFFICACY | ULCERATIVE-COLITIS | MULTICENTER EXPERIENCE | MAINTENANCE THERAPY | INDUCTION THERAPY | ACTIVITY INDEX | GASTROENTEROLOGY & HEPATOLOGY | REMISSION | Drug Hypersensitivity - etiology | Antibodies, Monoclonal, Humanized - adverse effects | Antibodies, Monoclonal, Humanized - therapeutic use | Humans | Hemoglobinometry | Male | Adrenal Cortex Hormones - therapeutic use | Colitis, Ulcerative - blood | Remission Induction | Crohn Disease - blood | Crohn Disease - drug therapy | Treatment Failure | Adolescent | Gastrointestinal Agents - therapeutic use | Female | Gastrointestinal Agents - adverse effects | Retrospective Studies | Colitis, Ulcerative - drug therapy | Drug Therapy, Combination | Weight Gain | Child | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Serum Albumin - metabolism | Adolescence | Pediatrics | Inflammatory bowel diseases | Laboratories | Hypersensitivity | Systematic review | Antagonists | Tumor necrosis factor-α | Patients | Factorial experiments | Crohns disease | Inflammatory bowel disease | Intestine | Gastroenterology | Hemoglobin | Remission | TNF inhibitors | Tumor necrosis factor-TNF | Children | Colon | Tumors | Crohn’s disease
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6. Full Text Enhanced acquisition of antibiotic-resistant intestinal E. coli during the first year of life assessed in a prospective cohort study
by Hetzer, Benjamin and Orth-Höller, Dorothea and Würzner, Reinhard and Kreidl, Peter and Lackner, Michaela and Müller, Thomas and Knabl, Ludwig and Geisler-Moroder, Daniel Rudolf and Mellmann, Alexander and Sesli, Özcan and Holzknecht, Jeanett and Noce, Damia and Boonpala, Orawan and Akarathum, Noppadon and Chotinaruemol, Somporn and Prelog, Martina and Oberdorfer, Peninnah
Antimicrobial Resistance and Infection Control, ISSN 2047-2994, 05/2019, Volume 8, Issue 1, pp. 1 - 13
Background Increasing bacterial resistance to antibiotics is a serious problem worldwide. We sought to record the acquisition of antibiotic-resistant... 
Persistence | Neonates | Multiresistance | Escherichia coli | Antibiotic resistance | Transmission | Children | Pediatrics | Antimicrobial agents | Infections | Drug resistance | Epidemiology | Studies | Babies | Ethics | Microbiota | Hospitals | Antibiotics | E coli | Newborn babies | Bacteria | Feces | Trends
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7. Full Text Vedolizumab use after failure of TNF-[alpha] antagonists in children and adolescents with inflammatory bowel disease
by Schneider, Anna-Maria and Weghuber, Daniel and Hetzer, Benjamin and Entenmann, Andreas and Muller, Thomas and Zimmermann, Georg and Schutz, Sebastian and Huber, Wolf-Dietrich and Pichler, Judith
BMC Gastroenterology, ISSN 1471-230X, 09/2018, Volume 18, Issue 1
Vedolizumab is safe and effective in adult patients with Crohn's disease (CD) and ulcerative colitis (UC); however, data in children with inflammatory bowel... 
Tumor necrosis factor inhibitors | Dosage and administration | Children | Drug therapy | Pediatric research | Diseases
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8. Full Text The beginning of the end? Extensive dieback of an open-grown Amur honeysuckle stand in northern Kentucky, USA
by Boyce, Richard L and Brossart, Stephanie N and Bryant, Laura A and Fehrenbach, Logan A and Hetzer, Rachael and Holt, Julie E and Parr, Benjamin and Poynter, Zachary and Schumacher, Cody and Stonebraker, Sandra N and Thatcher, Michael D and Vater, Mark
Biological Invasions, ISSN 1387-3547, 10/2014, Volume 16, Issue 10, pp. 2017 - 2023
Amur honeysuckle (Lonicera maackii) is recognized as one of the most important invasive species in the Ohio River Valley. In 2012–2013, an outbreak of... 
Life Sciences | Decline | Invasive species | Dieback | Lonicera maackii | Freshwater & Marine Ecology | Ecology | Insolibasidium deformans | Developmental Biology | Plant Sciences | Honeysuckle leaf blight | INVASIVE SHRUB | FOREST | INSOLIBASIDIUM-DEFORMANS | PLANTS | ECOLOGY | SHRUB LONICERA-MAACKII | BIODIVERSITY CONSERVATION | UNDERSTORY | LEAF | Plant diseases | Flowers & plants | Plant populations | Nonnative species
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9. Full Text SPINT2 (HAI-2) missense variants identified in congenital sodium diarrhea/tufting enteropathy affect the ability of HAI-2 to inhibit prostasin but not matriptase
by Holt-Danborg, Lasse and Vodopiutz, Julia and Nonboe, Annika W and De Laffolie, Jan and Skovbjerg, Signe and Wolters, Victorien M and Müller, Thomas and Hetzer, Benjamin and Querfurt, Alexander and Zimmer, Klaus-Peter and Jensen, Jan K and Entenmann, Andreas and Heinz-Erian, Peter and Vogel, Lotte K and Janecke, Andreas R
Human Molecular Genetics, ISSN 0964-6906, 03/2019, Volume 28, Issue 5, pp. 828 - 841
Abstract The syndromic form of congenital sodium diarrhea (SCSD) is caused by bi-allelic mutations in SPINT2, which encodes a Kunitz-type serine protease... 
PROTEASE MATRIPTASE | GENE | EPCAM | TUFTING ENTEROPATHY | BIOCHEMISTRY & MOLECULAR BIOLOGY | FACTOR ACTIVATOR INHIBITOR-2 | GENETICS & HEREDITY | CLOSURE | CLEAVAGE | ZYMOGEN
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10. Full Text Nuclear Translocation of RELB Is Increased in Diseased Human Liver and Promotes Ductular Reaction and Biliary Fibrosis in Mice
by Elßner, Christin and Goeppert, Benjamin and Longerich, Thomas and Scherr, Anna-Lena and Stindt, Jan and Nanduri, Lahiri Kanth and Rupp, Christian and Kather, Jakob Nikolas and Schmitt, Nathalie and Kautz, Nicole and Breuhahn, Kai and Ismail, Lars and Heide, Danijela and Hetzer, Jenny and García-Beccaria, María and Hövelmeyer, Nadine and Waisman, Ari and Urbanik, Toni and Mueller, Sebastian and Gdynia, Georg and Banales, Jesus M and Roessler, Stephanie and Schirmacher, Peter and Jäger, Dirk and Schölch, Sebastian and Keitel, Verena and Heikenwalder, Mathias and Schulze-Bergkamen, Henning and Köhler, Bruno Christian
Gastroenterology, ISSN 0016-5085, 03/2019, Volume 156, Issue 4, pp. 1190 - 1205.e14
Cholangiocyte proliferation and ductular reaction contribute to the onset and progression of liver diseases. Little is known about the role of the... 
BAFF | RANKL | Vascular Cell Adhesion Protein 1 | LIGHT | TRANSCRIPTION FACTORS | APOPTOSIS | ACTIVATION | HEPATOCARCINOGENESIS | SCLEROSING CHOLANGITIS | INFLAMMATION | CIRRHOSIS | MOUSE MODEL | GASTROENTEROLOGY & HEPATOLOGY | NF-KAPPA-B | EXPRESSION | Liver diseases | Liver | Analysis | Fibrosis
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11. Anomalous Diffusion of Single Particles in Cytoplasm
by Benjamin M Regner and Dejan Vucinic and Cristina Domnisoru and Thomas M Bartol and Martin W Hetzer and Daniel M Tartakovsky and Terrence J Sejnowski
Biophysical Journal, ISSN 0006-3495, 04/2013, Volume 104, Issue 8, p. 1652
  The crowded intracellular environment poses a formidable challenge to experimental and theoretical analyses of intracellular transport mechanisms. Our... 
Measurement | Cytoskeleton | Comparative analysis | Brownian movements | Cytoplasm
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12. Full Text HBEGF, SRA1, and IK: Three cosegregating genes as determinants of cardiomyopathy
by Friedrichs, Frauke and Zugck, Christian and Rauch, Gerd-Jörg and Ivandic, Boris and Weichenhan, Dieter and Müller-Bardorff, Margit and Meder, Benjamin and Mokhtari, Nour Eddine El and Regitz-Zagrosek, Vera and Hetzer, Roland and Schäfer, Arne and Schreiber, Stefan and Chen, Jian and Neuhaus, Isaac and Ji, Ruiru and Siemers, Nathan O and Frey, Norbert and Rottbauer, Wolfgang and Katus, Hugo A and Stoll, Monika
Genome Research, ISSN 1088-9051, 03/2009, Volume 19, Issue 3, pp. 395 - 403
Human dilated cardiomyopathy (DCM), a disorder of the cardiac muscle, causes considerable morbidity and mortality and is one of the major causes of sudden... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | HEAVY-CHAIN GENE | HEART-FAILURE | PROLIFERATION | FAMILIAL DILATED CARDIOMYOPATHY | LINKAGE DISEQUILIBRIUM | HUMAN GENOME | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PROTEIN GENES | GENETICS & HEREDITY | MUSCLE FILAMENT TITIN | MUTATIONS | CLUSTER | Humans | Ventricular Function, Left - genetics | Zebrafish - embryology | RNA, Untranslated - genetics | Case-Control Studies | Cytokines - physiology | Intercellular Signaling Peptides and Proteins - physiology | Cardiomyopathies - genetics | Chromosome Segregation - physiology | RNA, Untranslated - physiology | Cytokines - genetics | Cell Line | Animals, Genetically Modified | Intercellular Signaling Peptides and Proteins - genetics | Chromosome Mapping | Zebrafish - genetics | Chromosomes, Human, Pair 5 | Linkage Disequilibrium | Heparin-binding EGF-like Growth Factor | Animals | RNA, Long Noncoding | Embryo, Nonmammalian | Inflammation - genetics | Genetic Markers - physiology | Polymorphism, Single Nucleotide | Cluster Analysis | Pathology | Vertebrates | Cardiomyopathy | Genetic variation | Causes of | Genetic aspects | Research | Heart diseases | Letter
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13. Full Text Defect detection strategies and process partitioning for single-expose EUV patterning
by Meli, Luciana and Petrillo, Karen and De Silva, Anuja and Arnold, John and Felix, Nelson and Robinson, Chris and Briggs, Benjamin and Matham, Shravan and Mignot, Yann and Shearer, Jeffrey and Hamieh, Bassem and Hontake, Koichi and Huli, Lior and Lemley, Corey and Hetzer, Dave and Liu, Eric and Akiteru, Ko and Kawakami, Shinichiro and Shimoaoki, Takeshi and Hashimoto, Yusaku and Ichinomiya, Hiroshi and Kai, Akiko and Tanaka, Koichiro and Jain, Ankit and Choi, Heungsoo and Saville, Barry and Lenox, Chet
Journal of Micro/ Nanolithography, MEMS, and MOEMS, ISSN 1932-5150, 01/2019, Volume 18, Issue 1, p. 1
The key challenge for enablement of a second node of single-expose EUV patterning is understanding and mitigating the patterning-related defects that narrow... 
stochastic defects | inspection techniques | LCDU | CDU | single-expose EUV patterning | MATERIALS SCIENCE, MULTIDISCIPLINARY | NANOSCIENCE & NANOTECHNOLOGY | OPTICS | ENGINEERING, ELECTRICAL & ELECTRONIC
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14. Full Text "Enhanced acquisition of antibiotic-resistant intestinal E. coli during the first year of life assessed in a prospective cohort study"
by Hetzer, B and Orth-Holler, D and Wurzner, R and Kreidl, P and Lackner, M and Muller, T and Knabl, L and Geisler-Moroder, DR and Mellmann, A and Sesli, O and Holzknecht, J and Noce, D and Boonpala, O and Akarathum, N and Chotinaruemol, S and Prelog, M and Oberdorfer, P
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL, ISSN 2047-2994, 05/2019, Volume 8, Issue 1, p. 79
BackgroundIncreasing bacterial resistance to antibiotics is a serious problem worldwide. We sought to record the acquisition of antibiotic-resistant... 
Neonates | MICROFLORA | INFECTIOUS DISEASES | ASIA-PACIFIC REGION | Escherichia coli | Transmission | ESCHERICHIA-COLI | GUT | MICROBIOLOGY | COLONIZATION | MICROBIOTA | ANTIMICROBIAL RESISTANCE | Persistence | TRIMETHOPRIM-RESISTANT | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | GRAM-NEGATIVE BACILLI | HEALTHY-CHILDREN | Multiresistance | Antibiotic resistance | Children | Comparative analysis | Drug resistance in microorganisms
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15. Defect detection strategies and process partitioning for SE EUV patterning
by Meli, Luciana and Petrillo, Karen and De Silva, Anuja and Arnold, John and Felix, Nelson and Robinson, Chris and Briggs, Benjamin and Matham, Shravan and Mignot, Yann and Shearer, Jeffrey and Hamieh, Bassem and Hontake, Koichi and Huli, Lior and Lemley, Corey and Hetzer, Dave and Liu, Eric and Akiteru, Ko and Kawakami, Shinichiro and Shimoaoki, Takeshi and Hashimoto, Yusaku and Ichinomiya, Hiroshi and Kai, Akiko and Tanaka, Koichiro and Jain, Ankit and Choi, Heungsoo and Saville, Barry and Lenox, Chet
Proceedings of SPIE - The International Society for Optical Engineering, ISSN 0277-786X, 2018, Volume 10583
inspection techniques | LCDU | Single-Expose EUV patterning | CDU | Stochastic defects
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16. Full Text Nuclear Translocation of RELB Is Increased in Diseased Human Liver and Promotes Ductular Reaction and Biliary Fibrosis in Mice
by Elßner, Christin and Goeppert, Benjamin and Longerich, Thomas and Scherr, Anna-Lena and Stindt, Jan and Nanduri, Lahiri Kanth and Rupp, Christian and Kather, Jakob Nikolas and Schmitt, Nathalie and Kautz, Nicole and Breuhahn, Kai and Ismail, Lars and Heide, Danijela and Hetzer, Jenny and García-Beccaria, María and Hövelmeyer, Nadine and Waisman, Ari and Urbanik, Toni and Mueller, Sebastian and Gdynia, Georg and Banales, Jesus M and Roessler, Stephanie and Schirmacher, Peter and Jäger, Dirk and Schölch, Sebastian and Keitel, Verena and Heikenwalder, Mathias and Schulze-Bergkamen, Henning and Köhler, Bruno Christian
Gastroenterology, 11/2018
Cholangiocyte proliferation and ductular reaction contribute to the onset and progression of liver diseases. Little is known about the role of the... 
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17. A transapical or transluminal approach to aortic valve implantation does not attenuate the inflammatory response
by O'Brien, Benjamin and Pasic, Miralem and Kuppe, Hermann and Hetzer, Roland and Habazettl, Helmut and Kukucka, Marian
Heart Surgery Forum, ISSN 1098-3511, 04/2011, Volume 14, Issue 2, pp. E110 - E113
Cardiopulmonary bypass (CPB) and cardiac surgery cause an inflammatory response, as measurable by an increase in the concentration of C-reactive protein (CRP),... 
Body Mass Index | C-Reactive Protein | Health Status Indicators | Cardiopulmonary Bypass - adverse effects | Humans | Heart Valve Prosthesis Implantation - methods | Male | Cardiac Surgical Procedures - adverse effects | Statistics as Topic | Aortic Valve - surgery | Inflammation - etiology | Aortic Valve - pathology | Regression Analysis | Heart Valve Prosthesis Implantation - adverse effects | Biomarkers | Female | Aged | Inflammation - prevention & control | Retrospective Studies | Chronic Disease
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