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Nature Genetics, ISSN 1061-4036, 2012, Volume 44, Issue 10, pp. 1104 - 1110
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 10/2016, Volume 22, Issue 19, pp. 4837 - 4847
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2009, Volume 106, Issue 43, pp. 18351 - 18356
Journal Article
Science Translational Medicine, ISSN 1946-6234, 10/2013, Volume 5, Issue 209, pp. 209ra153 - 209ra153
We characterized genome alterations in 1255 clinically annotated lung tumors of all histological subgroups to identify genetically defined and clinically... 
GEFITINIB | FUSION | GENE | ADENOCARCINOMA | OPEN-LABEL | SQUAMOUS-CELL CARCINOMAS | HUMAN CANCER | ACTIVATING MUTATIONS | DRIVER MUTATIONS | EGFR | MEDICINE, RESEARCH & EXPERIMENTAL | NRF2 | CANCER | CELL BIOLOGY | Lung Neoplasms - genetics | Lung Neoplasms - classification | Automation | Genomics | Humans | Lung Neoplasms - pathology | Lung Neoplasms - diagnosis | Genome, Human - genetics
Journal Article
Nature genetics, ISSN 1061-4036, 2012, Volume 44, Issue 11, pp. 1199 - 1206
Journal Article
Journal Article
Leukemia, ISSN 0887-6924, 09/2012, Volume 26, Issue 9, pp. 2039 - 2051
Journal Article
Nature medicine, ISSN 1078-8956, 2014, Volume 20, Issue 9, pp. 1027 - 1034
Journal Article
by George, J and Lim, J.S and Jang, S.J and Cun, Y.P and Ozretic, L and Kong, G and Leenders, F and Lu, X and Fernandez-Cuesta, L and Bosco, G and Muller, C and Dahmen, I and Jahchan, N.S and Park, K.S and Yang, D and Karnezis, A.N and Vaka, D and Torres, A and Wang, M.S and Korbel, J.O and Menon, R and Chun, S.M and Kim, D and Wilkerson, M and Hayes, N and Engelmann, D and Putzer, B and Bos, M and Michels, S and Vlasic, I and Seidel, D and Pinther, B and Schaub, P and Becker, C and Altmuller, J and Yokota, J and Kohno, T and Iwakawa, R and Tsuta, K and Noguchi, M and Muley, T and Hoffmann, H and Schnabel, P.A and Petersen, I and Chen, Y and Soltermann, A and Tischler, V and Choi, C.M and Kim, Y.H and Massion, P.P and Zou, Y and Jovanovic, D and Kontic, M and Wright, G.M and Russell, P.A and Solomon, B and Koch, I and Lindner, M and Muscarella, L.A and la Torre, A and Field, J.K and Jakopovic, M and Knezevic, J and Castanos-Velez, E and Roz, L and Pastorino, U and Brustugun, O.T and Lund-Iversen, M and Thunnissen, E and Kohler, J and Schuler, M and Botling, J and Sandelin, M and Sanchez-Cespedes, M and Salvesen, H.B and Achter, V and Lang, U and Bogus, M and Schneider, P.M and Zander, T and Ansen, S and Hallek, M and Wolf, J and Vingron, M and Yatabe, Y and Travis, W.D and Nurnberg, P and Reinhardt, C and Perner, S and Heukamp, L and Buttner, R and Haas, S.A and Brambilla, E and Peifer, M and Sage, J and Thomas, R.K and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Lungmedicin och allergologi and Uppsala universitet and Institutionen för medicinska vetenskaper
Nature, ISSN 0028-0836, 2015, Volume 524, Issue 7563, pp. 47 - 53
We have sequenced the genomes of 110 small cell lung cancers (SCLC), one of the deadliest human cancers. In nearly all the tumours analysed we found bi-allelic... 
NEUROENDOCRINE TUMORS | PATHWAY | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | IN-VIVO | GENES | CYCLE ARREST | NOTCH | C-KIT | MUTATIONS | CARCINOMA | Neurosecretory Systems - pathology | Receptors, Notch - metabolism | Chromosome Breakpoints | Genomics | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Male | Receptors, Notch - genetics | Gene Expression Profiling | Tumor Suppressor Protein p53 - genetics | Small Cell Lung Carcinoma - metabolism | Tumor Suppressor Proteins - genetics | Neurosecretory Systems - metabolism | Female | Nuclear Proteins - genetics | Disease Models, Animal | Lung Neoplasms - genetics | Signal Transduction - genetics | Small Cell Lung Carcinoma - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Genome, Human - genetics | Small Cell Lung Carcinoma - pathology | Tumor Protein p73 | Animals | Cyclin D1 - genetics | Retinoblastoma Protein - genetics | Alleles | Cell Line, Tumor | Mice | Gene mutations | Analysis | Exome sequencing | Lung cancer, Small cell | Genetic aspects | Drug therapy | Cancer | Pathogenesis | Lung cancer | Genomes | Mutation | Kinases | Gene expression | Cancer therapies | Tumors | Clinical Medicine | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Cancer and Oncology | Klinisk medicin | Cancer och onkologi
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2012, Volume 109, Issue 42, pp. 17034 - 17039
Journal Article