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1. Full Text Hydroxypyridinone chelators: From iron scavenging to radiopharmaceuticals for PET imaging with gallium-68
by Cusnir, Ruslan and Imberti, Cinzia and Hider, Robert C and Blower, Philip J and Ma, Michelle T
International journal of molecular sciences, ISSN 1661-6596, 01/2017, Volume 18, Issue 1, pp. 116 - 116
Iron overload | Molecular imaging | Gallium | Hydroxypyridinone | Deferiprone | Bifunctional chelators | Positron emission tomography | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Animals | Humans | Positron-Emission Tomography | Chelating Agents - pharmacology | Gallium Radioisotopes - chemistry | Pyridones - chemistry | Iron - metabolism | Radiopharmaceuticals - pharmacology | Pyridones - pharmacology | Medical imaging | Index Medicus | deferiprone | iron overload | bifunctional chelators | hydroxypyridinone | gallium | positron emission tomography | molecular imaging
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2. Full Text Iron speciation in the cytosol: an overview
by Hider, Robert C and Kong, Xiaole
Dalton transactions : an international journal of inorganic chemistry, ISSN 1477-9226, 2/2013, Volume 42, Issue 9, pp. 322 - 3229
Physical Sciences | Chemistry, Inorganic & Nuclear | Chemistry | Science & Technology | Cytosol - enzymology | Sulfur - metabolism | Animals | Molecular Chaperones - metabolism | Oxidation-Reduction | Humans | Iron - chemistry | Cytosol - metabolism | Mitochondria - metabolism | Iron - metabolism | Index Medicus
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3. Full Text The Role of Deferiprone in Iron Chelation
by Hider, Robert C and Hoffbrand, A. Victor
The New England journal of medicine, ISSN 0028-4793, 11/2018, Volume 379, Issue 22, pp. 2140 - 2150
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Thalassemia - therapy | Iron Chelating Agents - therapeutic use | Erythrocyte Transfusion - adverse effects | Iron Overload - drug therapy | Humans | Deferoxamine - therapeutic use | Chelation Therapy | Iron Chelating Agents - adverse effects | Deferiprone - pharmacokinetics | Iron Overload - etiology | Anemia, Sickle Cell - therapy | Deferiprone - adverse effects | Deferiprone - therapeutic use | Drug Therapy, Combination | Iron Chelating Agents - pharmacokinetics | Chelation therapy | Usage | Blood transfusions | Brain | Excretion | Disease | Neutrophils | Phlebotomy | Clinical trials | Iron | Studies | Chelation | Ataxia | Chelating agents | Drug dosages | Neutropenia | Index Medicus | Abridged Index Medicus
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4. Full Text The crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategy
by Gaeta, Alessandra and Hider, Robert C
British journal of pharmacology, ISSN 0007-1188, 12/2005, Volume 146, Issue 8, pp. 1041 - 1059
Aβ‐amyloid | Neurodegeneration | protein aggregation | chelation therapy | iron | copper | α‐synuclein | oxidative stress | prion protein | Oxidative stress | Protein aggregation | Aβ-amyloid | Iron | Copper | Prion protein | Chelation therapy | α-synuclein | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Biological and medical sciences | Pharmacology. Drug treatments | Medical sciences | Prion Diseases - physiopathology | Oxidative Stress | Humans | Parkinson Disease - drug therapy | Neurodegenerative Diseases - drug therapy | Amyloid beta-Peptides - metabolism | Copper - metabolism | Parkinson Disease - metabolism | Prions - metabolism | Alzheimer Disease - physiopathology | Prion Diseases - drug therapy | Alzheimer Disease - drug therapy | Ions | Chelating Agents - pharmacology | Neurodegenerative Diseases - metabolism | Parkinson Disease - physiopathology | Iron - metabolism | Metals - metabolism | Animals | Manganese - metabolism | Neurodegenerative Diseases - physiopathology | Proteins - metabolism | Alzheimer Disease - metabolism | alpha-Synuclein - metabolism | Prion Diseases - metabolism | Index Medicus | Review
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5. Full Text The Efficacy of Iron Chelators for Removing Iron from Specific Brain Regions and the Pituitary-Ironing out the Brain
by Crichton, Robert R and Ward, Roberta J and Hider, Robert C
Pharmaceuticals (Basel, Switzerland), ISSN 1424-8247, 09/2019, Volume 12, Issue 3, p. 138
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | pituitary | neurodegenerative diseases | iron | brain | chelation
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6. Full Text Glutathione: a key component of the cytoplasmic labile iron pool
by Hider, Robert C and Kong, Xiao L
Biometals, ISSN 0966-0844, 12/2011, Volume 24, Issue 6, pp. 1179 - 1187
Life Sciences | Biochemistry, general | Cytoplasmic labile iron pool | Microbiology | Plant Physiology | Iron | Pharmacology/Toxicology | Medicine/Public Health, general | Cell Biology | Glutathione | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Oxidation-Reduction | Glutathione - metabolism | Humans | Iron - chemistry | Models, Molecular | Cytoplasm - metabolism | Mitochondria - metabolism | Iron - metabolism | Animals | Ligands | Protein Conformation | Sulfhydryl Compounds - chemistry | Glutathione - chemistry | Molecular Structure | Sulfur - chemistry | Enzymes | Thiols | Heme | Cellular biology | Metabolism | Protein synthesis | Synthesis | Clusters | Affinity | Determinants | Dimers | Pools | Speciation | Index Medicus
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7. Full Text Metals ions and neurodegeneration
by Molina-Holgado, Francisco and Hider, Robert C and Gaeta, Alessandra and Williams, Robert and Francis, Paul
Biometals, ISSN 0966-0844, 6/2007, Volume 20, Issue 3, pp. 639 - 654
Life Sciences | Biochemistry, general | Oxidative stress | Protein aggregation | Physical Chemistry | Neurodegeneration | Iron | A β -amyloid | α -Synuclein | Chelation therapy | α-Synuclein | Aβ-amyloid | Prions - metabolism | Ions - chemistry | Iron Chelating Agents - therapeutic use | Prions - genetics | Oxidation-Reduction | Oxidative Stress | Humans | Neurodegenerative Diseases - therapy | Neurodegenerative Diseases - metabolism | Ions - metabolism | Iron Chelating Agents - metabolism | Metals - metabolism | Metals - chemistry | Amyloid beta-Peptides - genetics | Amyloid beta-Peptides - metabolism | Molecular Structure | alpha-Synuclein - genetics | alpha-Synuclein - metabolism | Metal industry | Pathology | Metals | Parkinsons disease | Ions | Pharmacology | Alzheimers disease | Neurological disorders | Index Medicus
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