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Journal of the American Society of Nephrology : JASN, ISSN 1046-6673, 01/2020, p. ASN.2019050443
Mutations in the gene encoding inverted formin-2 (INF2), a member of the formin family of actin regulatory proteins, are among the most common causes of... 
Journal Article
Molecular Biology of the Cell, ISSN 1059-1524, 12/2018, Volume 29, Issue 25, pp. 2969 - 2978
A fundamental question in cell biology concerns how cells move, and this has been the subject of intense research for decades. In the 1990s, a major leap... 
LISTERIA-MONOCYTOGENES | F-ACTIN | NUCLEOTIDE EXCHANGE | LEADING-EDGE | ADP-ACTIN | ARP2/3 COMPLEX | N-WASP | ALDRICH-SYNDROME PROTEIN | FILAMENT BINDING | MOLECULAR-MECHANISMS | CELL BIOLOGY
Journal Article
Journal Article
Molecular Biology of the Cell, ISSN 1059-1524, 10/2016, Volume 27, Issue 20, pp. 3109 - 3121
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 09/2000, Volume 150, Issue 6, pp. 1311 - 1320
We purified native WASp (Wiskott-Aldrich Syndrome protein) from bovine thymus and studied its ability to stimulate actin nucleation by Arp2/3 complex. WASp... 
Prenylation | GBD | Membrane | Neutrophil | Thymus | LISTERIA-MONOCYTOGENES | thymus | FISSION YEAST | membrane | POLYMERIZATION | GTP-BINDING PROTEINS | neutrophil | CELL BIOLOGY | SPATIAL CONTROL | ACANTHAMOEBA-PROFILIN | prenylation | N-WASP | DEPOLYMERIZING PROTEIN | FILAMENT NUCLEATION | MOTILITY | Original
Journal Article
Nature Cell Biology, ISSN 1465-7392, 10/2007, Volume 9, Issue 10, pp. 1110 - 1121
Journal Article
JOURNAL OF CELL SCIENCE, ISSN 0021-9533, 09/2019, Volume 132, Issue 18, p. jcs234435
Recent studies show that mitochondria and actin filaments work together in two contexts: (1) increased cytoplasmic calcium induces cytoplasmic actin... 
COMPLEX | FUSION | MITOPHAGY | OMA1 | CLEAVAGE | DRP1 | CELL BIOLOGY | Depolarization | Arp2/3 complex | PARKIN | Mitochondria | CCCP | INF2 | OPA1 | FISSION | PROTEASE
Journal Article
Journal Article
Journal of cell science, 08/2019
Recent studies show that mitochondria and actin filaments work together in two contexts: 1) increased cytoplasmic calcium induces cytoplasmic actin... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2020, Volume 117, Issue 1, pp. 439 - 447
INF2 is a formin protein that accelerates actin polymerization. A common mechanism for formin regulation is autoinhibition, through interaction between the... 
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 12/2017, Volume 216, Issue 12, p. 4123
Drp1 is a dynamin guanosine triphosphatase important for mitochondrial and peroxisomal division. Drp1 oligomerization and mitochondrial recruitment are... 
Subpopulations | Oligomerization | Populations | Guanosine | Polymerization | Mammals | Cells | Mammalian cells | Recruitment | Proteins | Oligomers | Mitochondria | Receptors | Triphosphatase | Filaments | Actin | Dynamin | Division | Endoplasmic reticulum
Journal Article
Organic Letters, ISSN 1523-7060, 10/2017, Volume 19, Issue 19, pp. 5154 - 5157
A chemical foundation for function-oriented studies of pectenotoxin 2 (PTX2) is described. A synthesis of the bicyclic GH-system, and the design and synthesis... 
SPIROACETAL | OXIDATION | ENANTIOSELECTIVE EPOXIDATION | SHELLFISH TOXINS | P53-DEFICIENT TUMORS | CONSTRUCTION | FRAGMENT | CHEMISTRY, ORGANIC | ASYMMETRIC SYNTHESES | PART II | MEDIATED APOPTOSIS | Furans - chemistry | Pyrans - chemistry | Molecular Structure | Letter
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 01/2018, Volume 217, Issue 1, p. 251
Mitochondrial division requires division of both the inner and outer mitochondrial membranes (IMM and OMM, respectively). Interaction with endoplasmic... 
Membranes | Calcium | Polymerization | Calcium (mitochondrial) | Cells | Calcium influx | Mammalian cells | Recruitment | Electron transport chain | Mitochondria | Actin | Myosin | Dynamin | Electron transport | Endoplasmic reticulum
Journal Article
Biophysical Journal, ISSN 0006-3495, 01/2014, Volume 106, Issue 2, pp. 571a - 571a
Journal Article
Chemical Communications: Chem Comm, ISSN 1359-7345, 09/2014, Volume 50, Issue 81, pp. 12037 - 12039
We present a versatile method to characterize ATPase and kinase activities and discover new inhibitors of these proteins. The proton NMR-based assay directly... 
Proteins | Hydrolysis | Screening | Inhibitors | Monitors | Kinases | ATP | Monitoring
Journal Article