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1. Molecular mechanisms in Legionella pathogenesis
by Hilbi, Hubert
2013, Current topics in microbiology and immunology, ISBN 9783642405914, Volume 376
Emerging infectious diseases | Bacteriology
Web Resource
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2. Molecular Mechanisms in Legionella Pathogenesis
by Hilbi, Hubert
2013, ISBN 3642405908
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3. Legionella
: methods and protocols
by Buchrieser, Carmen and Hilbi, Hubert
2013, Methods in molecular biology, ISBN 1627031618, Volume 954
Legionnaires' disease | Legionella
Web Resource
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4. Full Text Formation of a pathogen vacuole according to Legionella pneumophila: how to kill one bird with many stones
by Finsel, Ivo and Hilbi, Hubert
Cellular Microbiology, ISSN 1462-5814, 07/2015, Volume 17, Issue 7, pp. 935 - 950
Summary Legionella species are ubiquitous, waterborne bacteria that thrive in numerous ecological niches. Yet, in contrast to many other environmental... 
NUCLEOTIDE-EXCHANGE FACTOR | STRUCTURAL BASIS | EFFECTOR PROTEIN DRRA | MICROBIOLOGY | ENDOPLASMIC-RETICULUM | LEGIONNAIRES-DISEASE | HOST-CELL DEATH | RAB GTPASE FUNCTION | NF-KAPPA-B | IV SECRETION SYSTEM | E3 UBIQUITIN LIGASE | CELL BIOLOGY | Host-Pathogen Interactions | Legionella pneumophila - immunology | Vacuoles - microbiology | Amoeba - parasitology | Phagocytes - microbiology | Models, Biological | Humans | Vacuoles - metabolism | Virulence Factors - metabolism | Legionella pneumophila - growth & development | Phagocytes - immunology | Legionella pneumophila | Legionnaires disease | Bacteriology
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5. Full Text Preface
by Buchrieser, Carmen and Hilbi, Hubert
Methods in Molecular Biology, ISSN 1064-3745, 2019, Volume 1921, pp. v - xviii
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6. Full Text Migration of Acanthamoeba castellanii Through Legionella Biofilms
by Hochstrasser, Ramon and Hilbi, Hubert
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2019, Volume 1921, pp. 79 - 89
The amoeba-resistant bacterium Legionella pneumophila infects humans through aerosols and thereby can cause a life-threatening pneumonia termed Legionnaires'... 
Cell motility | Biofilm formation | Green fluorescent protein | Confocal microscopy | Legionella pneumophila | Single-cell tracking | Acanthamoeba castellanii | Host-pathogen interactions | Type IV secretion
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7. Full Text Molecular Pathogenesis of Shigella spp.: Controlling Host Cell Signaling, Invasion, and Death by Type III Secretion
by Gunnar N. Schroeder and Hubert Hilbi
Clinical Microbiology Reviews, ISSN 0893-8512, 01/2008, Volume 21, Issue 1, pp. 134 - 156
Classifications Services CMR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
SHI-2 PATHOGENICITY ISLAND | COMPLETE GENOME SEQUENCE | SALMONELLA-CONTAINING VACUOLE | LARGE VIRULENCE PLASMID | FLAGELLAR MASTER OPERON | MONOCYTE-DERIVED MACROPHAGES | MICROBIOLOGY | ACTIN-BASED MOTILITY | ENTEROINVASIVE-ESCHERICHIA-COLI | ALDRICH-SYNDROME PROTEIN | INTERLEUKIN-1-BETA CONVERTING-ENZYME | Macrophages - physiology | Epithelial Cells - metabolism | Virulence Factors - genetics | Signal Transduction | Humans | Virulence | Bacterial Proteins - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Biological Evolution | Locomotion | Shigella - genetics | Epithelial Cells - microbiology | Cell Death | Bacterial Proteins - metabolism | Virulence Factors - metabolism | Biological Transport - physiology | Shigella - metabolism | Macrophages - microbiology | Dysentery, Bacillary - microbiology | Shigella - pathogenicity | Reviews
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8. Full Text Secretive Bacterial Pathogens and the Secretory Pathway
by Hilbi, Hubert and Haas, Albert
Traffic, ISSN 1398-9219, 09/2012, Volume 13, Issue 9, pp. 1187 - 1197
Eukaryotic cells possess two extensive endomembrane systems, each consisting of several sub‐compartments connected by vesicular trafficking. One of these... 
Salmonella | endosomal pathway | Chlamydia | type III secretion system | Brucella | type IV secretion system | secretory pathway | Legionella | pathogen vacuole | Golgi apparatus | vesicle trafficking | Pathogen vacuole | Vesicle trafficking | Endosomal pathway | Type III secretion system | Secretory pathway | Type IV secretion system | NUCLEOTIDE-EXCHANGE FACTOR | LEGIONELLA-PNEUMOPHILA | SALMONELLA-CONTAINING VACUOLE | CHLAMYDIA-TRACHOMATIS | EFFECTOR PROTEIN DRRA | SMALL-MOLECULE INHIBITOR | CELL BIOLOGY | INTRACELLULAR REPLICATION | ENDOPLASMIC-RETICULUM | TRACHOMATIS INCLUSION MEMBRANE | RAB GTPASE FUNCTION | Chlamydia - chemistry | Humans | Secretory Pathway | Salmonella - pathogenicity | Endosomes - metabolism | Brucella - chemistry | Protein Transport | Host-Pathogen Interactions | Animals | Salmonella - chemistry | Chlamydia - pathogenicity | Bacterial Proteins - metabolism | Legionella - pathogenicity | Eukaryotic Cells - microbiology | Brucella - pathogenicity | Legionella - chemistry | Pathogens | Bacteriology | Substance P | Vesicles
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9. Legionella pneumophila. Preface
by Hilbi, Hubert
Current topics in microbiology and immunology, ISSN 0070-217X, 2013, Volume 376, p. v
Legionnaires' Disease - etiology | Animals | Legionella pneumophila - pathogenicity | Humans
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10. Full Text Role of the small GTPase Rap1 in signal transduction, cell dynamics and bacterial infection
by Hilbi, Hubert and Kortholt, Arjan
Small GTPases, ISSN 2154-1248, 09/2019, Volume 10, Issue 5, pp. 336 - 342
Rap1 belongs to the Ras family of small GTPases, which are involved in a multitude of cellular signal transduction pathways and have extensively been linked to... 
host-pathogen interactions | Dictyostelium | cell migration | macrophage | motility | Legionella | adhesion | type IV secretion | small GTPase | pathogen vacuole | chemotaxis
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11. Full Text Formation of a pathogen vacuole according toLegionella pneumophila: how to kill one bird with many stones
: Legionellapathogen vacuole formation
by Finsel, Ivo and Hilbi, Hubert
Cellular Microbiology, ISSN 1462-5814, 07/2015, Volume 17, Issue 7, pp. 935 - 950
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12. Full Text Live cell imaging of phosphoinositide dynamics during Legionella infection
by Weber, Stephen and Hilbi, Hubert
Methods in Molecular Biology, ISSN 1064-3745, 2014, Volume 1197, pp. 153 - 167
The "accidental" pathogen Legionella pneumophila replicates intracellularly in a distinct compartment, the Legionella-containing vacuole (LCV). To form this... 
Dictyostelium discoideum | Pathogen vacuole | Phosphoinositides | Real-time fluorescence microscopy | Legionella pneumophila | Effector proteins | Amoeba | Type IV secretion | Host-Pathogen Interactions | Legionella - metabolism | Animals | Humans | Legionellosis - pathology | Bacterial Proteins - metabolism | Phosphatidylinositols - metabolism | Protein Transport - physiology | Dictyostelium - metabolism
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13. Full Text Modulation of phosphoinositide metabolism by pathogenic bacteria
by Hilbi, Hubert
Cellular Microbiology, ISSN 1462-5814, 11/2006, Volume 8, Issue 11, pp. 1697 - 1706
Summary Phosphoinositide metabolism plays a pivotal role in the regulation of receptor-mediated signal transduction, actin remodelling and membrane dynamics.... 
MYCOBACTERIUM-TUBERCULOSIS | PHAGOSOME MATURATION ARREST | SALMONELLA-DUBLIN | LEGIONELLA-PNEUMOPHILA | PNEUMOPHILA REPLICATION VACUOLE | SYNDROME PROTEIN OCRL1 | EPITHELIAL-CELLS | ENTERICA SEROVAR TYPHIMURIUM | TRANS-GOLGI NETWORK | MICROBIOLOGY | DICTYOSTELIUM-DISCOIDEUM | CELL BIOLOGY | Bacteria - growth & development | Bacteria - metabolism | Animals | Phosphatidylinositol Phosphates - metabolism | Models, Biological | Humans | Phosphatidylinositols - metabolism | Molecular Structure | Phosphoric Monoester Hydrolases - metabolism | Phosphatidylinositol Phosphates - chemistry
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14. Full Text The natural alternative: protozoa as cellular models for Legionella infection
by Hoffmann, Christine and Harrison, Christopher F and Hilbi, Hubert
Cellular Microbiology, ISSN 1462-5814, 01/2014, Volume 16, Issue 1, pp. 15 - 26
Summary The severe pneumonia known as Legionnaires' disease occurs following infection by the Gram‐negative bacterium Legionella pneumophila. Normally resident... 
ACANTHAMOEBA-CASTELLANII | PATHOGEN-HOST INTERACTIONS | PNEUMOPHILA INFECTION | PHAGOSOME MATURATION | INTRACELLULAR GROWTH | AUTOINDUCER SYNTHASE LQSA | DIFFERENTIAL INFECTION | HARTMANNELLA-VERMIFORMIS | MICROBIOLOGY | DICTYOSTELIUM-DISCOIDEUM | LEGIONNAIRES-DISEASE BACTERIUM | CELL BIOLOGY | Host-Pathogen Interactions | Models, Theoretical | Alveolata | Animals | Humans | Legionnaires' Disease | Legionella pneumophila - physiology | Eukaryotic Cells - microbiology | Proteins | Mitochondrial DNA | Health aspects | Analysis | Cells | Legionnaires disease | Infections | Bacteriology
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15. Full Text Phosphoinositide lipids and the Legionella pathogen vacuole
by Haneburger, Ina and Hilbi, Hubert
Current Topics in Microbiology and Immunology, ISSN 0070-217X, 2013, Volume 376, pp. 155 - 173
Subversion of vesicle trafficking is vital for intracellular survival of Legionella pneumophila within host cells. L. pneumophila produces several type... 
Phosphatidylinositol 3-Kinases - physiology | Vacuoles - microbiology | Membrane Lipids - physiology | Phosphatidylinositols - physiology | Legionella pneumophila - pathogenicity | Humans
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16. Quantitative Imaging Flow Cytometry of Legionella-Infected Dictyostelium Amoebae Reveals the Impact of Retrograde Trafficking on Pathogen Vacuole Composition
by Amanda Welin and Stephen Weber and Hubert Hilbi
Applied and Environmental Microbiology, ISSN 0099-2240, 06/2018, Volume 84, Issue 11, p. e00158-18
The ubiquitous environmental bacterium Legionella pneumophila survives and replicates within amoebae and human macrophages by forming a Legionella-containing... 
Flow cytometry | Pneumonia | Molecular structure | Trafficking | Legionella pneumophila | Homology | Macrophages | Proteins | Actin | Bacteria | Genetics | Wiskott-Aldrich syndrome | Pathogens | Composition | Secretion | Metabolism | Calnexin | Retrograde transport | Environmental impact | Molecular chains | Golgi apparatus | Intracellular | Endosomes | Guanosinetriphosphatase | Amoeba
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17. Full Text Quantitative Imaging Flow Cytometry of Legionella-Containing Vacuoles in Dually Fluorescence-Labeled Dictyostelium
by Welin, Amanda and Weber, Stephen and Hilbi, Hubert and Hilbi, Hubert
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2019, Volume 1921, pp. 161 - 177
Legionella pneumophila enters and replicates within protozoan and mammalian phagocytes by forming through a conserved mechanism a specialized intracellular... 
Dictyostelium discoideum | Membrane dynamics | Pathogen vacuole | Vesicle trafficking | Imaging flow cytometry | ImageStream | Legionella pneumophila | Phagosome | Endoplasmic reticulum | Phagocytosis | Type IV secretion
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18. Full Text Molecular Mechanisms in Legionella Pathogenesis
by Hilbi, Hubert
10/2013, 2014, Current Topics in Microbiology and Immunology, ISBN 3642405908, Volume 376, 297
This book examines different facets of Legionnaires' disease, focusing on comparative phagocyte infection, virulence gene regulation, biochemical functions of... 
Bacteriology | Emerging infectious diseases | Medical Microbiology | Infectious Diseases | Molecular Medicine | Biomedicine | Immunology | Legionnaires' disease | Legionella pneumophila
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19. Full Text Single Cell Analysis of Legionella and Legionella-Infected Acanthamoeba by Agarose Embedment
by Personnic, Nicolas and Striednig, Bianca and Hilbi, Hubert and Hilbi, Hubert
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2019, Volume 1921, pp. 191 - 204
Legionella pneumophila resides in multispecies biofilms, where it infects and replicates in environmental protozoa such as Acanthamoeba castellanii. Studies on... 
Infection | Embedment | Fluorescent protein | Microcolony | Single cell | Flow chamber | Legionella | Acanthamoeba castellanii | Agarose
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20. Full Text Legionella-Containing Vacuoles Capture PtdIns(4)P-Rich Vesicles Derived from the Golgi Apparatus
by Weber, Stephen and Steiner, Bernhard and Welin, Amanda and Hilbi, Hubert
mBio, ISSN 2161-2129, 12/2018, Volume 9, Issue 6, p. e02420-18
is the causative agent of a pneumonia termed Legionnaires' disease. The facultative intracellular bacterium employs the Icm/Dot type IV secretion system (T4SS)... 
host-pathogen interaction | Dictyostelium | live-cell imaging | Legionella | type IV secretion | pathogen vacuole | phosphoinositide lipid | Amoeba | effector protein | Golgi apparatus | vesicle trafficking
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