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1. Full Text Challenges in molecular testing in non-small-cell lung cancer patients with advanced disease
by Hiley, Crispin T, MD and Le Quesne, John, FRCPath and Santis, George, Prof and Sharpe, Rowena, PhD and de Castro, David Gonzalez, Prof and Middleton, Gary, Prof and Swanton, Charles, Prof
The Lancet (British edition), ISSN 0140-6736, 2016, Volume 388, Issue 10048, pp. 1002 - 1011
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Severity of Illness Index | Receptor, Epidermal Growth Factor - genetics | Biomarkers, Tumor - analysis | Carcinoma, Non-Small-Cell Lung - genetics | Humans | Lung Neoplasms - pathology | Receptor, Epidermal Growth Factor - analysis | Receptor Protein-Tyrosine Kinases - genetics | Biomarkers, Tumor - genetics | Mutation | High-Throughput Nucleotide Sequencing - methods | Medical colleges | Care and treatment | Therapeutics | Respiratory agents | Lung cancer, Non-small cell | Homeopathy | Materia medica and therapeutics | Ultrasonic imaging | Biomedical research | Histopathology | Immunotherapy | Lung cancer | Diagnostic tests | Tumors | Index Medicus | Abridged Index Medicus
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2. Full Text Cognitive impairment in survivors of irradiated brain tumors is multifactorial: Implications of polypharmacy with antiepileptics?
by Hiley, Crispin T
Journal of clinical oncology, ISSN 0732-183X, 12/2015, Volume 33, Issue 34, pp. 4122 - 4122
Life Sciences & Biomedicine | Oncology | Science & Technology | Piperidines - therapeutic use | Humans | Female | Male | Brain Neoplasms - drug therapy | Brain Neoplasms - radiotherapy | Cognition Disorders - drug therapy | Indans - therapeutic use | Index Medicus
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3. Full Text Great debate: surgery versus stereotactic radiotherapy for early-stage non-small cell lung cancer
by Hiley, Crispin and Salem, Ahmed and Batchelor, Tim and McDonald, Fiona and Evison, Matthew
Thorax, ISSN 0040-6376, 03/2020, Volume 75, Issue 3, pp. 198 - 199
Life Sciences & Biomedicine | Respiratory System | Science & Technology | Datasets | Ostomy | Thoracic surgery | Hospitals | Comorbidity | Decision making | Lung cancer | Surgery | Physiology | Radiation therapy | Patients | Index Medicus
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4. Full Text Deciphering intratumor heterogeneity and temporal acquisition of driver events to refine precision medicine
by Hiley, Crispin and de Bruin, Elza C and McGranahan, Nicholas and Swanton, Charles
Genome Biology, ISSN 1474-7596, 08/2014, Volume 15, Issue 8, pp. 453 - 453
Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Neoplasms - genetics | Humans | Biomarkers, Tumor - agonists | Biomarkers, Tumor - genetics | Genetic Heterogeneity | Clonal Evolution | Precision Medicine | Index Medicus | Review
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5. Full Text Genomic landscape of platinum resistant and sensitive testicular cancers
by Loveday, Chey and Litchfield, Kevin and Proszek, Paula Z and Cornish, Alex J and Santo, Flavia and Levy, Max and Macintyre, Geoff and Holryod, Amy and Broderick, Peter and Dudakia, Darshna and Benton, Barbara and Al Bakir, Maise and Hiley, Crispin and Grist, Emily and Swanton, Charles and Huddart, Robert and Powles, Tom and Chowdhury, Simon and Shipley, Janet and O'Connor, Simon and Brenton, James D and Reid, Alison and de Castro, David Gonzalez and Houlston, Richard S and Turnbull, Clare
Nature communications, ISSN 2041-1723, 05/2020, Volume 11, Issue 1, pp. 2189 - 2189
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Chemotherapy | Sequences | Platinum | Copy number | Mutation | Testes | Testicular cancer | Tumors | Index Medicus
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6. Full Text Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse
by Chemi, Francesca and Rothwell, Dominic G and McGranahan, Nicholas and Gulati, Sakshi and Abbosh, Chris and Pearce, Simon P and Zhou, Cong and Wilson, Gareth A and Jamal-Hanjani, Mariam and Birkbak, Nicolai and Pierce, Jackie and Kim, Chang Sik and Ferdous, Saba and Burt, Deborah J and Slane-Tan, Daniel and Gomes, Fabio and Moore, David and Shah, Rajesh and Al Bakir, Maise and Hiley, Crispin and Veeriah, Selvaraju and Summers, Yvonne and Crosbie, Philip and Ward, Sophia and Mesquita, Barbara and Dynowski, Marek and Biswas, Dhruva and Tugwood, Jonathan and Blackhall, Fiona and Miller, Crispin and Hackshaw, Allan and Brady, Ged and Swanton, Charles and Dive, Caroline and TRACERx Consortium
Nature medicine, ISSN 1078-8956, 10/2019, Volume 25, Issue 10, pp. 1534 - 1539
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Carcinoma, Non-Small-Cell Lung - pathology | Pulmonary Veins - pathology | Carcinoma, Non-Small-Cell Lung - surgery | Neoplastic Cells, Circulating - pathology | Carcinoma, Non-Small-Cell Lung - genetics | Humans | Middle Aged | Male | Carcinoma, Non-Small-Cell Lung - diagnosis | Neoplasm Recurrence, Local - diagnosis | Neoplasm Recurrence, Local - surgery | Genome, Human - genetics | Neoplasm Recurrence, Local - pathology | Neoplasm Metastasis | Aged, 80 and over | Adult | Female | Neoplasm Recurrence, Local - genetics | Aged | Biomarkers, Tumor - genetics | Neoplasm Staging | Gene Expression Regulation, Neoplastic - genetics | Care and treatment | Usage | Relapse | Genetic aspects | Excision (Surgery) | Research | Lung cancer, Non-small cell | Risk factors | Diseases | Profiling | Enumeration | Small cell lung carcinoma | Tumor cells | Lung cancer | Non-small cell lung carcinoma | Multivariate analysis | Patients | Metastases | Surgical instruments | Surgery | Mutation | Tumors | Index Medicus
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7. Full Text Is heterogeneity in stage 3 non-small cell lung cancer obscuring the potential benefits of dose-escalated concurrent chemo-radiotherapy in clinical trials?
by Hudson, Andrew and Chan, Clara and Woolf, David and McWilliam, Alan and Hiley, Crispin and O’Connor, James and Bayman, Neil and Blackhall, Fiona and Faivre-Finn, Corinne
Lung cancer (Amsterdam, Netherlands), ISSN 0169-5002, 04/2018, Volume 118, pp. 139 - 147
Heterogeneity | NSCLC | cCRT | Dose-escalation | Concurrent chemoradiotherapy | Stage 3 | Respiratory System | Oncology | Life Sciences & Biomedicine | Science & Technology | Carcinoma, Non-Small-Cell Lung - pathology | Radiotherapy Dosage | Carcinoma, Non-Small-Cell Lung - radiotherapy | Lung Neoplasms - drug therapy | Risk Assessment | Humans | Lung Neoplasms - radiotherapy | Lung Neoplasms - pathology | Clinical Trials as Topic | Chemoradiotherapy | Dose Fractionation, Radiation | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Carcinoma, Non-Small-Cell Lung - drug therapy | Neoplasm Staging | Index Medicus
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8. Full Text Spatial and temporal cancer evolution: causes and consequences of tumour diversity
by Hiley, Crispin T and Swanton, Charles
Clinical medicine (London, England), ISSN 1470-2118, 12/2014, Volume 14, Issue Suppl 6, pp. s33 - s37
evolution | heterogeneity | resistance | Cancer
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9. Full Text Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
by Jamal-Hanjani, Mariam and Constantin, Tudor and Le Quesne, John and Moore, David A and Rosenthal, Rachel and McGranahan, Nicholas and Martinson, Luke and Fraioli, Francesco and Al Bakir, Maise and Grönroos, Eva and Zambrana, Francisco and Johnson, Diana and Laycock, Joanne and Shafi, Seema and Matthews, Nik and Lee, Siow Ming and Borg, Elaine and Lawrence, David and Hayward, Martin and Kolvekar, Shyam and Panagiotopoulos, Nikolaos and Thakrar, Ricky and Ahmed, Asia and Summers, Yvonne and Naik, Ashwini and Joseph, Leena and Quinn, Anne Marie and Remmen, Hardy and Nakas, Apostolos and Russell, Peter and Ismail, Babikir and Kornaszewska, Malgorzata and Oukrif, Dahmane and Hartley, John A and Bell, Harriet and Ngai, Yenting and Szallasi, Zoltan and Herrero, Javier and Quezada, Sergio A and Van Loo, Peter and Rabinowitz, Matthew and Shaw, Jacqui A and Zimmermann, Bernhard G and Gorman, Pat and Murugaesu, Nirupa and Hynds, Robert E and Mitter, Richard and Goldman, Jacki and Phillimore, Ben and Nye, Emma and Graca, Sofia and Joshi, Kroopa and Furness, Andrew and Wong, Yien Ning Sophia and Simeon, Celia and Hector, Gemma and Aranda, Marie and Mendes, Ruheena and George, Jeremy and Navani, Neal and Califano, Raffaele and Krysiak, Piotr and Evison, Matthew and Bishop, Paul and Novasio, Juliette and Rogan, Jane and Tugwood, Jonathan and Chemi, Francesca and Pierce, Jackie and Kerr, Amy and Monteiro, William and Nelson, Louise and Bennett, Jonathan and Verjee, Azmina and Wilcox, Maggie and Smith, Sean and Ottensmeier, Christian and Alzetani, Aiman and Shaw, Emily and Bowman, Alex and Rice, Alexandra and Raubenheimer, Hilgardt and Cufari, Maria Elena and Kwayie, Angela and Buderi, Silviu and Azcarate, Leire and Chavan, Hema and Green, Sophie and Lau, Kelvin and Schmid, Peter and Conibear, John and Light, Teresa and Horey, Tracey and Edwards, John and Hill, Jennifer and Matthews, Sue and Fisher, Patricia and Gosney, John and Postmus, Pieter and Dentro, Stefan and TRACERx Consortium and The PEACE Consortium and TRACERx consortium and PEACE consortium and The PEACE consortium and The TRACERx consortium
Nature (London), ISSN 0028-0836, 04/2017, Volume 545, Issue 7655, pp. 446 - 451
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Biopsy - methods | Early Detection of Cancer - methods | Humans | Lung Neoplasms - pathology | Cell Tracking | Neoplasm Recurrence, Local - pathology | DNA, Neoplasm - blood | DNA Mutational Analysis | Cell Lineage - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Limit of Detection | Reproducibility of Results | Carcinoma, Non-Small-Cell Lung - surgery | Carcinoma, Non-Small-Cell Lung - genetics | Neoplasm Recurrence, Local - diagnosis | Tumor Burden | Multiplex Polymerase Chain Reaction | Postoperative Care - methods | Clone Cells - metabolism | Disease Progression | Neoplasm Metastasis - genetics | Drug Resistance, Neoplasm - genetics | Clone Cells - pathology | Neoplasm Metastasis - pathology | Neoplasm Metastasis - diagnosis | Carcinoma, Non-Small-Cell Lung - blood | Lung Neoplasms - surgery | Neoplasm Recurrence, Local - genetics | Lung Neoplasms - blood | DNA, Neoplasm - genetics | Evolution, Molecular | Lung cancer | Development and progression | Genetic aspects | Phylogeny | Nucleotide sequencing | Metastasis | Observations | Methods | DNA sequencing | Index Medicus
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10. Full Text Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution
by Hiley, Crispin T and Wilson, Gareth A and Veeriah, Selvaraju and Herrero, Javier and Swanton, Charles and Swanton, Charles and Czyzewska-Khan, Justyna and Gorman, Pat and Wilson, Gareth and Birkbak, Nicolai J and Watkins, Thomas B.K and McGranahan, Nicholas and Mitter, Richard and Escudero, Mickael and Rowan, Andrew and Xu, Hang and Turajlic, Samra and Stone, Richard Kevin and Denner, Tamara and Costa, Marta and Phillimore, Ben and Joshi, Kroopa and Furness, Andrew and Ben Aissa, Assma and Wong, Yien Ning Sophia and Quezada, Sergio and Hartley, John A and Lowe, Helen L and Herrero, Javier and Lawrence, David and Falzon, Mary and Borg, Elaine and Marafioti, Teresa and Thakrar, Ricky and Papadatos-Pastos, Dionysis and Choudhary, Junaid and Califano, Raffaele and