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ISSN 1553-734X, 2018
Viral infections are one of the major causes of death worldwide, with HIV infection alone resulting in over 1.2 million casualties per year. Antiviral drugs... 
Viruses--Evolution | Drug resistance | Bioinformatics | Computational biology
Journal Article
PLoS pathogens, ISSN 1553-7374, 07/2017, Volume 13, Issue 7, pp. e1006488 - e1006488
[This corrects the article DOI: 10.1371/journal.ppat.1005535.]. 
Journal Article
ISSN 1553-7374, 2016
A priority for HIV cure research is measuring latent infection that can fuel viral recrudescence if patients cease antiretroviral therapy (ART). One important... 
Pathology | Diseases--Recrudescence | HIV infections--Pathogenesis | Latent virus diseases | Virology
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2014, Volume 111, Issue 43, pp. 15598 - 15598
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 512, Issue 1, pp. 74 - 77
The viral reservoir represents a critical challenge for human immunodeficiency virus type 1 (HIV-1) eradication strategies(1-5). However, it remains unclear... 
LATENT INFECTION | REPLICATION | INITIATION | MULTIDISCIPLINARY SCIENCES | ACTIVE ANTIRETROVIRAL THERAPY | VACCINE | PREVENTION | DYNAMICS | IMMUNODEFICIENCY VIRUS-INFECTION | DEPENDS | HIV-1 INFECTION | DNA, Viral - biosynthesis | Macaca mulatta - immunology | Simian Immunodeficiency Virus - growth & development | DNA, Viral - analysis | Male | RNA, Viral - blood | Rectum - virology | Macaca mulatta - virology | Simian Acquired Immunodeficiency Syndrome - virology | Proviruses - genetics | Time Factors | Treatment Failure | Female | Disease Models, Animal | Simian Immunodeficiency Virus - immunology | Virus Replication - drug effects | Anti-Retroviral Agents - therapeutic use | Anti-Retroviral Agents - pharmacology | Viremia - drug therapy | Simian Immunodeficiency Virus - physiology | DNA, Viral - blood | Carrier State - virology | Animals | Simian Acquired Immunodeficiency Syndrome - drug therapy | Simian Acquired Immunodeficiency Syndrome - immunology | Viremia - virology | Anti-Retroviral Agents - administration & dosage | Carrier State - drug therapy | Kinetics | Viral Load - drug effects | Simian Immunodeficiency Virus - drug effects | Physiological aspects | Simian immunodeficiency virus | Virulence (Microbiology) | Studies | Antiretroviral drugs | Lymphocytes | Human immunodeficiency virus--HIV | Infections | Monkeys & apes | Deoxyribonucleic acid--DNA | Index Medicus
Journal Article
by De Rubeis, Silvia and He, Xin and Goldberg, Arthur P and Poultney, Christopher S and Samocha, Kaitlin and Cicek, A. Ercument and Kou, Yan and Liu, Li and Fromer, Menachem and Walker, Susan and Singh, Tarjinder and Klei, Lambertus and Kosmicki, Jack and Fu, Shih-Chen and Aleksic, Branko and Biscaldi, Monica and Bolton, Patrick F and Brownfeld, Jessica M and Cai, Jinlu and Campbell, Nicholas G and Carracedo, Angel and Chahrour, Maria H and Chiocchetti, Andreas G and Coon, Hilary and Crawford, Emily L and Crooks, Lucy and Curran, Sarah R and Dawson, Geraldine and Duketis, Eftichia and Fernandez, Bridget A and Gallagher, Louise and Geller, Evan and Guter, Stephen J and Hill, R. Sean and Ionita-Laza, Iuliana and Gonzalez, Patricia Jimenez and Kilpinen, Helena and Klauck, Sabine M and Kolevzon, Alexander and Lee, Irene and Lei, Jing and Lehtimäki, Terho and Lin, Chiao-Feng and Ma'ayan, Avi and Marshall, Christian R and McInnes, Alison L and Neale, Benjamin and Owen, Michael J and Ozaki, Norio and Parellada, Mara and Parr, Jeremy R and Purcell, Shaun and Puura, Kaija and Rajagopalan, Deepthi and Rehnström, Karola and Reichenberg, Abraham and Sabo, Aniko and Sachse, Michael and Sanders, Stephan J and Schafer, Chad and Schulte-Rüther, Martin and Skuse, David and Stevens, Christine and Szatmari, Peter and Tammimies, Kristiina and Valladares, Otto and Voran, Annette and Wang, Li-San and Weiss, Lauren A and Willsey, A. Jeremy and Yu, Timothy W and Yuen, Ryan K. C and Cook, Edwin H and Freitag, Christine M and Gill, Michael and Hultman, Christina M and Lehner, Thomas and Palotie, Aarno and Schellenberg, Gerard D and Sklar, Pamela and State, Matthew W and Sutcliffe, James S and Walsh, Christopher A and Scherer, Stephen W and Zwick, Michael E and Barrett, Jeffrey C and Cutler, David J and Roeder, Kathryn and Devlin, Bernie and Daly, Mark J and Buxbaum, Joseph D and Homozygosity Mapping Collaborative and DDD Study and Autism Sequencing Consortium and UK10K Consortium and Homozygosity Mapping Collaborative for Autism and The Autism Sequencing Consortium and The DDD Study
Nature, ISSN 0028-0836, 11/2014, Volume 515, Issue 7526, pp. 209 - 215
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2014, Volume 111, Issue 43, p. 15598
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2015, Volume 125, Issue 5, pp. 1901 - 1912
Reversal of HIV-1 latency by small molecules is a potential cure strategy. This approach will likely require effective drug combinations to achieve high levels... 
SUPPRESSIVE ANTIRETROVIRAL THERAPY | MEDICINE, RESEARCH & EXPERIMENTAL | VIRUS REACTIVATION | ACTIVATION | RESERVOIR | IN-VIVO | GENE-EXPRESSION | CD4(+) T-CELLS | HISTONE DEACETYLASE INHIBITORS | NF-KAPPA-B | LIFELONG PERSISTENCE | Anti-HIV Agents - pharmacology | Transcription, Genetic - drug effects | Lymphokines - secretion | Humans | Middle Aged | RNA, Messenger - analysis | Male | Virus Latency - drug effects | Anti-HIV Agents - administration & dosage | HIV-1 - physiology | Phorbol Esters - pharmacology | Adult | Anti-HIV Agents - therapeutic use | Female | CD4-Positive T-Lymphocytes - virology | Drug Evaluation, Preclinical | Bryostatins - pharmacology | HIV-1 - drug effects | Lymphocyte Activation | HIV Infections - virology | Protein Kinase C - drug effects | Cells, Cultured | RNA, Viral - analysis | Virion - metabolism | Azepines - pharmacology | Drug Synergism | Triazoles - pharmacology | CD4-Positive T-Lymphocytes - secretion | HIV Infections - drug therapy | Histone Deacetylase Inhibitors - pharmacology | Disulfiram - pharmacology | CD4-Positive T-Lymphocytes - drug effects | Physiological aspects | Research | RNA | T cells | Drug therapy | HIV infection | Studies | Statistical analysis | Cytokines | Acquired immune deficiency syndrome--AIDS | Lymphocytes | T cell receptors | Mathematical models | Gene expression | Index Medicus | Abridged Index Medicus | HIV | Infectious disease | AIDS
Journal Article
PLoS Computational Biology, ISSN 1553-734X, 08/2014, Volume 10, Issue 8
  The bacterial core genome is of intense interest and the volume of whole genome sequence data in the public domain available to investigate it has increased... 
Studies | Datasets | Genomics | Genes | Population | Genomes | Genetic diversity | Public health | Data bases | Methods | Streptococcus infections | Evolutionary | Bacteria | Mathematical models | Estimates | Bayesian analysis | Gene sequencing
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2 - 2
Journal Article
Annals of Internal Medicine, ISSN 0003-4819, 09/2014, Volume 161, Issue 5, pp. 319 - 327
Journal Article