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American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 06/2019, Volume 199, Issue 12, p. 1579
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1400 - 11
The widespread use of electronic cigarettes (e-cigarettes or e-cig) is a growing public health concern. Diacetyl and its chemical cousin 2,3-pentanedione are... 
2,3-PENTANEDIONE | METABOLISM | MULTIDISCIPLINARY SCIENCES | RESPIRATORY TOXICITY | IN-VIVO | LUNG-DISEASE | MUCOCILIARY TRANSPORT | DIACETYL | ASSOCIATION | NASAL CILIA | CILIARY MOTILITY | Respiratory tract | Epithelial cells | Electronic cigarettes | Cytoskeleton | Epithelium | Cigarettes | Immunofluorescence | Ribonucleic acid--RNA | Diacetyl | Public health | Cilia
Journal Article
American journal of respiratory and critical care medicine, ISSN 1073-449X, 06/2019, Volume 199, Issue 12, pp. 1579 - 1579
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2018, Volume 13, Issue 5, pp. e0197105 - e0197105
Lymphangioleiomyomatosis (LAM) is a rare, almost exclusively female lung disease linked to inactivating mutations in tuberous sclerosis complex 2 (TSC2), a... 
Lung Neoplasms - genetics | Embryo, Mammalian - pathology | Signal Transduction | Humans | Lung Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Fibroblasts - pathology | Sirolimus - pharmacology | Embryo, Mammalian - metabolism | Lymphangioleiomyomatosis | Mice, Knockout | Animals | Insulin-Like Growth Factor II - genetics | Tuberous Sclerosis Complex 2 Protein | Tumor Suppressor Proteins - deficiency | Insulin-Like Growth Factor II - biosynthesis | Cell Line, Tumor | Mice | Fibroblasts - metabolism | Care and treatment | Lung diseases | Development and progression | Tumor suppressor genes | Genetic aspects | Insulin-like growth factors | Rapamycin | Dosage and administration | Drug resistance | Health aspects | TOR protein | Tuberous sclerosis 2 protein | Phosphorylation | Transcription | Disease | Lung | Critical care | Homology | Epidemiology | Sclerosis | Metastases | Proteins | Cell growth | Robustness (mathematics) | Imprinting | Fibroblasts | Angiomyolipoma | Autocrine signalling | Insulin-like growth factor II | Lesions | Informatics | Secretion | Developmental biology | Stat3 protein | Tuberous sclerosis | siRNA | Embryo fibroblasts | Gene expression | Ribonucleic acid--RNA | Insulin | Patients | Medicine | TSC2 protein | Womens health | Cell lines | Epigenetics | Ligands | Mutation | Cancer | Tumors | Index Medicus | RNA | Ribonucleic acid
Journal Article
European Respiratory Journal, ISSN 0903-1936, 05/2017, Volume 49, Issue 5, pp. 1700329 - 1700329
Asthma is a common airway disease that results from complex interactions among genetic and environmental factors. In the USA, asthma disparities by race and... 
AIRWAY RESPONSIVENESS | RESPIRATORY SYSTEM | ORMDL3 | HISPANICS | POPULATIONS | RISK | UPDATE | ADMIXTURE | ASSOCIATION | GENOME | Genetic Predisposition to Disease | Ethnic Groups | Humans | Asthma | Respiratory tract | Hispanic Americans | Respiratory tract diseases | Environmental factors | Minority & ethnic groups | Morbidity | Index Medicus
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 07/2019, Volume 116, Issue 27, pp. 13384 - 13393
Journal Article
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 04/2019, Volume 143, Issue 4, pp. 1633 - 1635
[...]characterization of rs12712142, which was annotated to the 3'UTR region of IL1RL1, showed that it introduces a new binding site for hsa-miR-452-5p, which... 
AMERICAN | GENETIC EPIDEMIOLOGY RESEARCH | HEALTH | IMMUNOLOGY | ALLERGY | Phenotypes | African Americans | Chromosome 6 | Genomes | Single-nucleotide polymorphism | Minority & ethnic groups | Chromosome 2 | Ethnic factors | Asthma | Impact analysis | Respiratory tract | Studies | 3' Untranslated regions | Interleukin 1 | Quality control | Adults | Chromosomes | Hispanics | Binding sites
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 05/2018, Volume 58, Issue 5, pp. 575 - 584
Journal Article
American journal of respiratory cell and molecular biology, 01/2019
Glucocorticoids, commonly used asthma controller medications, decrease symptoms in most patients, but some remain symptomatic despite high dose treatment. The... 
Journal Article
Respiratory research, ISSN 1465-9921, 01/2019, Volume 20, Issue 1, pp. 15 - 15
The acute respiratory distress syndrome (ARDS) is characterized by the acute onset of hypoxemia and bilateral lung infiltrates in response to an inciting... 
RNA sequencing | Respiratory failure | Acute respiratory distress syndrome (ARDS) | RNA-Seq | Bone marrow transplant | Transcriptome profiling | Hematopoietic stem cell transplantation | MANAGEMENT | SUBPHENOTYPES | PHENOTYPES | SIGNATURE | RESPIRATORY-DISTRESS-SYNDROME | SURVIVING SEPSIS CAMPAIGN | RESPIRATORY SYSTEM | PULMONARY COMPLICATIONS | SEPTIC SHOCK | INTERNATIONAL GUIDELINES | EXPRESSION | Hematopoietic Stem Cell Transplantation - trends | Sequence Analysis, RNA - trends | Humans | Middle Aged | Male | Transcriptome - genetics | Respiratory Distress Syndrome, Adult - blood | Sequence Analysis, RNA - methods | Respiratory Distress Syndrome, Adult - genetics | Hematopoietic Stem Cell Transplantation - adverse effects | Adult | Female | Registries | Respiratory Distress Syndrome, Adult - therapy | Acute respiratory distress syndrome | Hospital patients | Care and treatment | RNA | Mortality | Genes | Transplantation | Biological response modifiers | Blood banks | Hematopoietic stem cells | Stem cells | Bone marrow | Interferon | Comparative analysis | Health aspects | Intensive care | Transplants & implants | Lung | Stem cell transplantation | Blood | Gene sequencing | Hypoxemia | Peripheral blood | Respiratory therapy | Immune response | Gene expression | Ribonucleic acid--RNA | Patients | Morbidity | Hemopoiesis | Studies | Respiratory distress syndrome | Rheumatoid arthritis | Sepsis | Index Medicus | Research
Journal Article
Human Heredity, ISSN 0001-5652, 06/2018, Volume 83, Issue 1, p. 44
Over 140,000 transcriptomic studies performed in healthy and diseased cell and tissue types, at baseline and after exposure to various agents, are available in... 
Integration | Statistical analysis | DNA microarrays | Glucocorticoids | Data processing | Gene expression | Ribonucleic acid--RNA | Asthma
Journal Article
by Torgerson, Dara G and Ampleford, Elizabeth J and Chiu, Grace Y and Gauderman, W James and Gignoux, Christopher R and Graves, Penelope E and Himes, Blanca E and Levin, Albert M and Mathias, Rasika A and Hancock, Dana B and Baurley, James W and Eng, Celeste and Stern, Debra A and Celedón, Juan C and Rafaels, Nicholas and Capurso, Daniel and Conti, David V and Roth, Lindsey A and Soto-Quiros, Manuel and Togias, Alkis and Li, Xingnan and Myers, Rachel A and Romieu, Isabelle and Berg, David J. Van Den and Hu, Donglei and Hansel, Nadia N and Hernandez, Ryan D and Israel, Elliott and Salam, Muhammad T and Galanter, Joshua and Avila, Pedro C and Avila, Lydiana and Rodriquez-Santana, Jose R and Chapela, Rocio and Rodriguez-Cintron, William and Diette, Gregory B and Adkinson, N Franklin and Abel, Rebekah A and Ross, Kevin D and Shi, Min and Faruque, Mezbah U and Dunston, Georgia M and Watson, Harold R and Mantese, Vito J and Ezurum, Serpil C and Liang, Liming and Ruczinski, Ingo and Ford, Jean G and Huntsman, Scott and Chung, Kian Fan and Vora, Hita and Li, Xia and Calhoun, William J and Castro, Mario and Sienra-Monge, Juan J and Del Rio-Navarro, Blanca and Deichmann, Klaus A and Heinzmann, Andrea and Wenzel, Sally E and Busse, William W and Gern, James E and Lemanske, Robert F and Beaty, Terri H and Bleecker, Eugene R and Raby, Benjamin A and Meyers, Deborah A and London, Stephanie J and Gilliland, Frank D and Burchard, Esteban G and Martinez, Fernando D and Weiss, Scott T and Williams, L Keoki and Barnes, Kathleen C and Ober, Carole and Nicolae, Dan L and Study African Amer Asthma and GRAAD Study and CAMP and HARBORS Study and CARE Network and Study Genes Environm Admixture and SAPPHIRE and Mexico City Childhood Asthma and Childrens Hlth Study and Childhood Asthma Management Program (CAMP) and Genetic Research on Asthma in African Diaspora (GRAAD) Study and Childhood Asthma Research and Education (CARE) Network and Genetics of Asthma in Latino Americans (GALA) Study, Study of Genes-Environment and Admixture in Latino Americans (GALA2) and Study of African Americans, Asthma, Genes & Environments (SAGE) and Children's Health Study (CHS) and HARBORS study and Mexico City Childhood Asthma Study (MCAAS) and Study of Asthma Phenotypes and Pharmacogenomic Interactions by Race-Ethnicity (SAPPHIRE) and Genetic Research on Asthma in the African Diaspora (GRAAD) Study and Genetics of Asthma in Latino Americans (GALA) Study, the Study of Genes-Environment and Admixture in Latino Americans (GALA2) and the Study of African Americans, Asthma, Genes & Environments (SAGE)
Nature Genetics, ISSN 1061-4036, 09/2011, Volume 43, Issue 9, pp. 887 - 892
Journal Article
AMIA ... Annual Symposium proceedings. AMIA Symposium, 2018, Volume 2018, pp. 1561 - 1570
Electronic health record (EHR)-derived data has become an invaluable resource for biomedical research, but is seldom used for the study of the health impacts... 
Journal Article
by Demenais, Florence and Margaritte-Jeannin, Patricia and Barnes, Kathleen C and Cookson, William O. C and Altmüller, Janine and Ang, Wei and Barr, R. Graham and Beaty, Terri H and Becker, Allan B and Beilby, John and Bisgaard, Hans and Bjornsdottir, Unnur Steina and Bleecker, Eugene and Bønnelykke, Klaus and Boomsma, Dorret I and Bouzigon, Emmanuelle and Brightling, Christopher E and Brossard, Myriam and Brusselle, Guy G and Burchard, Esteban and Burkart, Kristin M and Bush, Andrew and Chan-Yeung, Moira and Chung, Kian Fan and Couto Alves, Alexessander and Curtin, John A and Custovic, Adnan and Daley, Denise and De Jongste, Johan C and Del-Rio-Navarro, Blanca E and Donohue, Kathleen M and Duijts, Liesbeth and Eng, Celeste and Eriksson, Johan G and Farrall, Martin and Fedorova, Yuliya and Feenstra, Bjarke and Ferreira, Manuel A and Freidin, Maxim B and Gajdos, Zofia and Gauderman, Jim and Gehring, Ulrike and Geller, Frank and Genuneit, Jon and Gharib, Sina A and Gilliland, Frank and Granell, Raquel and Graves, Penelope E and Gudbjartsson, Daniel F and Haahtela, Tari and Heckbert, Susan R and Heederik, Dick and Heinrich, Joachim and Heliövaara, Markku and Henderson, John and Himes, Blanca E and Hirose, Hiroshi and Hirschhorn, Joel N and Hofman, Albert and Holt, Patrick and Hottenga, Jouke and Hudson, Thomas J and Hui, Jennie and Imboden, Medea and Ivanov, Vladimir and Jaddoe, Vincent W. V and James, Alan and Janson, Christer and Jarvelin, Marjo-Riitta and Jarvis, Deborah and Jones, Graham and Jonsdottir, Ingileif and Jousilahti, Pekka and Kabesch, Michael and Kähönen, Mika and Kantor, David B and Karunas, Alexandra S and Khusnutdinova, Elza and Koppelman, Gerard H and Kozyrskyj, Anita L and Kreiner, Eskil and Kubo, Michiaki and Kumar, Rajesh and Kumar, Ashish and Kuokkanen, Mikko and Lahousse, Lies and Laitinen, Tarja and Laprise, Catherine and Lathrop, Mark and Lau, Susanne and Lee, Young-Ae and Lehtimäki, Terho and Letort, Sébastien and Levin, Albert M and Li, Guo and Liang, Liming and Loehr, Laura R and London, Stephanie J and Loth, Daan W and Manichaikul, Ani and ... and Australian Asthma Genetics Consort and Australian Asthma Genetics Consortium (AAGC) collaborators and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Lung- allergi- och sömnforskning and Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm and Uppsala universitet and Institutionen för medicinska vetenskaper and Centrum för klinisk forskning i Sörmland (CKFD)
Nature Genetics, ISSN 1061-4036, 01/2018, Volume 50, Issue 1, pp. 42 - 50
Journal Article