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Journal of Clinical Investigation, ISSN 0021-9738, 12/2014, Volume 124, Issue 12, pp. 5099 - 5099
The liver is capable of full regeneration following several types and rounds of injury, ranging from hepatectomy to toxin-mediated damage. The source of this... 
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2009, Volume 284, Issue 23, pp. 15458 - 15468
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2014, Volume 124, Issue 12, pp. 5099 - 5102
Journal Article
Nature Physics, ISSN 1745-2473, 05/2018, Volume 14, Issue 5, pp. 469 - 474
The emergence of complex organs is driven by the coordinated proliferation, migration and differentiation of precursor cells. The fate behaviour of these cells... 
MESP1 | MAINTENANCE | PROGENITORS | CELLS | COAGULATION | PHYSICS, MULTIDISCIPLINARY | Progeny | Animal models | Deformation | Dynamics | Statistical physics | Emergence | Organs | Transgenic | Homeostasis | Scaling | Physics | Complexity
Journal Article
ISSN 0012-1606, 2016
The liver and pancreas are critical organs maintaining whole body metabolism. Historically, the expansion of adult-derived cells from these organs in vitro has... 
stem cell | 3D cultures | liver | pancreas | niche signals | organoid
Journal Article
Journal Article
Nature Protocols, ISSN 1754-2189, 09/2016, Volume 11, Issue 9, p. 1724
Adult somatic tissues have proven difficult to expand in vitro, largely because of the complexity of recreating appropriate environmental signals in culture.... 
stem cell culture | genetic manipulation | liver | pancreas | organoid
Journal Article
ISSN 1745-2473, 2018
The emergence of complex organs is driven by the coordinated proliferation, migration and differentiation of precursor cells. The fate behaviour of these cells... 
Journal Article
DEVELOPMENT, ISSN 0950-1991, 06/2019, Volume 146, Issue 12, p. dev174557
During mouse embryogenesis, progenitors within the liver known as hepatoblasts give rise to adult hepatocytes and cholangiocytes. Hepatoblasts, which are... 
RAT-LIVER | HEPATOCYTES | Liver | MOUSE | Organoid | DEVELOPMENTAL BIOLOGY | BETA-CATENIN | Hepatoblast | Bipotent | Liver stem/progenitor cells | STEM/PROGENITOR CELLS | Lgr5 | DIFFERENTIATION | LONG-TERM EXPANSION | LIVER DEVELOPMENT | ADULT LIVER | EXPRESSION | Liver stem | 203 | Stem Cells and Regeneration | progenitor cells | Liver development
Journal Article
ISSN 1534-5807, 2018
Pancreas development involves a coordinated process in which an early phase of cell segregation is proceeded by a longer phase of lineage restriction,... 
Stem Cells | Morphogenesis | Cell Lineage | Animals | Cell Proliferation | Endocrine Cells | Gene Expression Regulation, Developmental | Cell Differentiation | Pancreas | Organogenesis | Acinar Cells
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 09/2017, Volume 60, Issue 17, pp. 7284 - 7299
Journal Article