Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (39) 39
animals (31) 31
mice (26) 26
humans (17) 17
male (17) 17
metabolism (12) 12
mice, inbred c57bl (11) 11
biochemistry & molecular biology (10) 10
glucose (10) 10
analysis (9) 9
hypoxia (9) 9
mice, knockout (9) 9
disease models, animal (8) 8
glycolysis (8) 8
liver (8) 8
mass spectrometry (8) 8
oxidative stress (8) 8
physiological aspects (8) 8
cancer (7) 7
glucose - metabolism (7) 7
metabolites (7) 7
multidisciplinary sciences (7) 7
rats (7) 7
cell biology (6) 6
energy metabolism (6) 6
liver - metabolism (6) 6
oxidation-reduction (6) 6
adenosine triphosphate - metabolism (5) 5
article (5) 5
cystathionine beta-synthase (5) 5
cystathionine beta-synthase - metabolism (5) 5
cysteine (5) 5
endocrinology & metabolism (5) 5
female (5) 5
gluconeogenesis (5) 5
glutathione (5) 5
hydrogen sulfide (5) 5
ischemia (5) 5
metabolome (5) 5
metabolomics (5) 5
myocardium - metabolism (5) 5
oxygen - metabolism (5) 5
rats, sprague-dawley (5) 5
research (5) 5
biomedicine (4) 4
blotting, western (4) 4
brain (4) 4
cells, cultured (4) 4
deficient mice (4) 4
endogenous modulator (4) 4
expression (4) 4
fatty acid-binding proteins - genetics (4) 4
health aspects (4) 4
identification (4) 4
ischemia-reperfusion injury (4) 4
medicine (4) 4
methylation (4) 4
neoplasm proteins - genetics (4) 4
neurosciences (4) 4
oxygen (4) 4
pathway (4) 4
rat-liver (4) 4
rodents (4) 4
science (4) 4
stress (4) 4
surgery (4) 4
transsulfuration (4) 4
alpha (3) 3
amino acids (3) 3
camphor 5-monooxygenase - chemistry (3) 3
carbon monoxide (3) 3
carbon monoxide - metabolism (3) 3
carbon monoxide - physiology (3) 3
carbon-monoxide (3) 3
cardiac & cardiovascular systems (3) 3
cells (3) 3
children (3) 3
colon-cancer (3) 3
cystine (3) 3
deficiency (3) 3
disease (3) 3
energy-metabolism (3) 3
fatty acids (3) 3
fatty acids - metabolism (3) 3
gas biology (3) 3
gene silencing (3) 3
gene-expression (3) 3
genetics & heredity (3) 3
glucose metabolism (3) 3
glutamate (3) 3
glutathione - metabolism (3) 3
hct116 cells (3) 3
heart failure (3) 3
hematology (3) 3
heme oxygenase (3) 3
heme oxygenase - metabolism (3) 3
hepatocytes - metabolism (3) 3
homeostasis (3) 3
homocysteine (3) 3
hydrogen sulfide - metabolism (3) 3
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway
by Yamamoto, Takehiro and Takano, Naoharu and Ishiwata, Kyoko and Ohmura, Mitsuyo and Nagahata, Yoshiko and Matsuura, Tomomi and Kamata, Aki and Sakamoto, Kyoko and Nakanishi, Tsuyoshi and Kubo, Akiko and Hishiki, Takako and Suematsu, Makoto
Nature Communications, ISSN 2041-1723, 03/2014, Volume 5, Issue 1, p. 3480
Haem oxygenase (HO)-1/carbon monoxide (CO) protects cancer cells from oxidative stress, but the gas-responsive signalling mechanisms remain unknown. Here we... 
COLON-CANCER | RAT-LIVER | OXIDATIVE STRESS | CARBON-MONOXIDE | ANTIOXIDANT STATUS | MULTIDISCIPLINARY SCIENCES | CYSTATHIONINE-BETA-SYNTHASE | HYDROGEN-SULFIDE | HEME OXYGENASE-1 | TUMOR-GROWTH | MASS-SPECTROMETRY | Neoplasms - metabolism | Oxidative Stress | Down-Regulation | Humans | Neoplasms - enzymology | Phosphofructokinase-2 - metabolism | Neoplasms - genetics | Phosphofructokinase-2 - genetics | Cell Line, Tumor | Glucose - metabolism | Glycolysis | Heme Oxygenase (Decyclizing) - metabolism | Methylation | Heme Oxygenase (Decyclizing) - genetics | Pentose Phosphate Pathway
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Hypoxic regulation of the cerebral microcirculation is mediated by a carbon monoxide-sensitive hydrogen sulfide pathway
by Takayuki Morikawa and Mayumi Kajimura and Tomomi Nakamura and Takako Hishiki and Tsuyoshi Nakanishi and Yoshinori Yukutake and Yoshiko Nagahata and Mami Ishikawa and Katsuji Hattori and Toshiki Takenouchi and Takao Takahashi and Isao Ishii and Kazuko Matsubara and Yasuaki Kabe and Shinichiro Uchiyama and Eiichiro Nagata and Moataz M. Gadalla and Solomon H. Snyder and Makoto Suematsu
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2012, Volume 109, Issue 4, pp. 1293 - 1298
Enhancement of cerebral blood flow by hypoxia is critical for brain function, but signaling systems underlying its regulation have been unclear. We report a... 
Enzymes | Brain | Arterioles | Neurons | Blood vessels | Physiological regulation | Sensors | Brain hypoxia | Vasodilation | Blood flow | Energy metabolism | Neurovascular unit | Gas biology | Gasotransmitter | MULTIDISCIPLINARY SCIENCES | H2S | CYSTATHIONINE BETA-SYNTHASE | DEFICIENT MICE | gas biology | OXYGEN | ENDOGENOUS MODULATOR | HEME | gasotransmitter | NEURAL ACTIVITY | energy metabolism | BRAIN | neurovascular unit | Hydrogen Sulfide - metabolism | Immunohistochemistry | 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid | Cerebrum - blood supply | DNA Primers - genetics | Cystathionine beta-Synthase - metabolism | Carbon Monoxide - metabolism | Blotting, Western | Microcirculation - physiology | Microscopy, Confocal | Animals | Analysis of Variance | Adenosine Triphosphate - metabolism | Mass Spectrometry | Hypoxia - physiopathology | Mice | Vasodilation - physiology | Heme Oxygenase (Decyclizing) - metabolism | Regional Blood Flow - physiology | Heme Oxygenase (Decyclizing) - genetics | Hydrogen sulfide | Microcirculation | Cerebral circulation | Physiological aspects | Hypoxia | Research | Biological control systems | Biological Sciences
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival
by Shiota, Megumi and Naya, Masayuki and Yamamoto, Takehiro and Hishiki, Takako and Tani, Takeharu and Takahashi, Hiroyuki and Kubo, Akiko and Koike, Daisuke and Itoh, Mai and Ohmura, Mitsuyo and Kabe, Yasuaki and Sugiura, Yuki and Hiraoka, Nobuyoshi and Morikawa, Takayuki and Takubo, Keiyo and Suina, Kentaro and Nagashima, Hideaki and Sampetrean, Oltea and Nagano, Osamu and Saya, Hideyuki and Yamazoe, Shogo and Watanabe, Hiroyuki and Suematsu, Makoto
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1561 - 16
Gold deposition with diagonal angle towards boehmite-based nanostructure creates random arrays of horse-bean-shaped nanostructures named gold-nanofeve (GNF).... 
CELLS | DIFFERENCE TIME-DOMAIN | IN-VITRO | SERINE | METABOLISM | CARBON-MONOXIDE | GLUTATHIONE | MULTIDISCIPLINARY SCIENCES | CYSTATHIONINE BETA-SYNTHASE | IDENTIFICATION | TAURINE | Gold - chemistry | Neoplasms - metabolism | Taurine - analogs & derivatives | Antioxidants - chemistry | Glutathione - metabolism | Transaminases - genetics | Antioxidants - metabolism | Humans | Liver - metabolism | Metal Nanoparticles - chemistry | Mice, Inbred C57BL | Gold - metabolism | Male | Spectrum Analysis, Raman - methods | Mice, SCID | Liver - chemistry | Animals | Neoplasms - genetics | Transaminases - metabolism | Female | Mice | Taurine - chemistry | Spectrum Analysis, Raman - instrumentation | Taurine - metabolism | Taurine | Quantum chemistry | Liver | Xenotransplantation | Serine | Parenchyma | Glycine | Metabolites | CD44 antigen | Spectrum analysis | Xenografts | Excitation spectra | Glutathione | Gold | Spectroscopy | Cell survival | Vibration | Immunodeficiency | Nanostructure | Raman spectroscopy | Survival | Glycolysis | Boehmite | Cancer | Tumors
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue
by Imaizumi, Yoichi and Okada, Yohei and Akamatsu, Wado and Koike, Masato and Kuzumaki, Naoko and Hayakawa, Hideki and Nihira, Tomoko and Kobayashi, Tetsuro and Ohyama, Manabu and Sato, Shigeto and Takanashi, Masashi and Funayama, Manabu and Hirayama, Akiyoshi and Soga, Tomoyoshi and Hishiki, Takako and Suematsu, Makoto and Yagi, Takuya and Ito, Daisuke and Kosakai, Arifumi and Hayashi, Kozo and Shouji, Masanobu and Nakanishi, Atsushi and Suzuki, Norihiro and Mizuno, Yoshikuni and Mizushima, Noboru and Amagai, Masayuki and Uchiyama, Yasuo and Mochizuki, Hideki and Hattori, Nobutaka and Okano, Hideyuki
Molecular Brain, ISSN 1756-6606, 2012, Volume 5, Issue 1, pp. 35 - 35
Background: Parkinson's disease (PD) is a neurodegenerative disease characterized by selective degeneration of dopaminergic neurons in the substantia nigra... 
Oxidative stress | Mitochondria | Parkinson's disease | Induced pluripotent stem cells | α-synuclein | Parkin | PROTEIN | DISORDERS | MECHANISMS | DEFICIENT MICE | DOPAMINERGIC-NEURONS | alpha-synuclein | NEUROSCIENCES | FIBROBLASTS | PLURIPOTENT STEM-CELLS | RECESSIVE JUVENILE PARKINSONISM | DISEASE | LEWY BODIES | Neurons - pathology | Humans | Middle Aged | Male | Membrane Potential, Mitochondrial - drug effects | Mitochondria - ultrastructure | Brain - metabolism | Neurons - ultrastructure | Carbonyl Cyanide m-Chlorophenyl Hydrazone - pharmacology | Adult | Female | Neurons - metabolism | Parkinson Disease - metabolism | Lewy Bodies - metabolism | Neurons - drug effects | Lewy Bodies - pathology | Induced Pluripotent Stem Cells - metabolism | Induced Pluripotent Stem Cells - pathology | Parkinson Disease - pathology | Induced Pluripotent Stem Cells - drug effects | Induced Pluripotent Stem Cells - ultrastructure | Mitochondria - metabolism | Mitochondria - drug effects | Mitochondria - pathology | Brain - drug effects | Mitochondrial Turnover - drug effects | Animals | Signal Transduction - drug effects | NF-E2-Related Factor 2 - metabolism | Brain - pathology | Aged | Mice | Oxidative Stress - drug effects | Postmortem Changes | alpha-Synuclein - metabolism | Parkinson’s disease
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Neuroprotective Role of Astroglia in Parkinson Disease by Reducing Oxidative Stress Through Dopamine-Induced Activation of Pentose-Phosphate Pathway
by Mashima, Kyoko and Takahashi, Shinichi and Minami, Kazushi and Izawa, Yoshikane and Abe, Takato and Tsukada, Naoki and Hishiki, Takako and Suematsu, Makoto and Kajimura, Mayumi and Suzuki, Norihiro
ASN Neuro, ISSN 1759-0914, 5/2018, Volume 10, p. 1759091418775562
Oxidative stress plays an important role in the onset and progression of Parkinson disease. Although released dopamine at the synaptic terminal is mostly... 
glucose | astrocytes | dopamine | glutathione | glutamate | reactive oxygen species | GLUCOSE-UTILIZATION | GLUTAMATE UPTAKE | NEUROSCIENCES | DEFICIENCY | OLIGONUCLEOTIDE MICROARRAY | METABOLISM | NOREPINEPHRINE TRANSPORTER | GENE-EXPRESSION | NEURONS | RAT-BRAIN | Pentose Phosphate Pathway - drug effects | Reactive Oxygen Species | Embryo, Mammalian | Coculture Techniques | Dose-Response Relationship, Drug | NF-E2-Related Factor 2 - genetics | Neurons - drug effects | Dopamine - metabolism | Astrocytes - drug effects | Brain - cytology | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Cells, Cultured | Dopamine - pharmacology | Hydrogen Peroxide - pharmacology | Rats | NF-E2-Related Factor 2 - deficiency | Rats, Sprague-Dawley | Mice, Knockout | Gene Expression Regulation - drug effects | Animals | Lactates - metabolism | Glucose - metabolism | Mice | Oxidative Stress - drug effects | Oxidative stress | Dopamine | Parkinsons disease
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text A possible role of microglia-derived nitric oxide by lipopolysaccharide in activation of astroglial pentose-phosphate pathway via the Keap1/Nrf2 system
by Iizumi, Takuya and Takahashi, Shinichi and Mashima, Kyoko and Minami, Kazushi and Izawa, Yoshikane and Abe, Takato and Hishiki, Takako and Suematsu, Makoto and Kajimura, Mayumi and Suzuki, Norihiro
Journal of Neuroinflammation, ISSN 1742-2094, 05/2016, Volume 13, Issue 1, p. 99
Background: Toll-like receptor 4 (TLR4) plays a pivotal role in the pathophysiology of stroke-induced inflammation. Both astroglia and microglia express TLR4,... 
Ara-C (cytosine β-d-arabinofuranoside hydrochloride) | LME (l-leucine methyl ester) | TLR4 (Toll-like receptor 4) | Astrocyte | ROS (reactive oxygen species) | RNS (reactive nitrogen species) | POSTISCHEMIC INFLAMMATION | OXIDATIVE STRESS | IMMUNOLOGY | LME (L-leucine methyl ester) | NEUROSCIENCES | Ara-C (cytosine beta-D-arabinofuranoside hydrochloride) | REACTIVE OXYGEN | IMMUNE-RESPONSES | CEREBRAL-ARTERY OCCLUSION | TOLL-LIKE RECEPTORS | GENE-EXPRESSION | ISCHEMIC BRAIN-INJURY | ENERGY-METABOLISM | NF-KAPPA-B | Immunohistochemistry | NF-E2-Related Factor 2 - physiology | Microglia - metabolism | Lipopolysaccharides - toxicity | Pentose Phosphate Pathway - physiology | Reactive Oxygen Species - metabolism | Oxidative Stress - physiology | Cells, Cultured | Rats | Kelch-Like ECH-Associated Protein 1 - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Rats, Sprague-Dawley | Blotting, Western | Stroke - metabolism | Animals | Spectrometry, Mass, Electrospray Ionization | Signal Transduction - physiology | In Vitro Techniques | Nitric Oxide - metabolism | Astrocytes - metabolism | Disease Models, Animal | Stroke (Disease) | Complications and side effects | Physiology, Pathological | Analysis | Influence | Inflammation | Research | Risk factors | Lipopolysaccharides
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Development of a highly sensitive device for counting the number of disease-specific exosomes in human sera
by Kabe, Yasuaki and Suematsu, Makoto and Sakamoto, Satoshi and Hirai, Miwa and Koike, Ikko and Hishiki, Takako and Matsuda, Atsushi and Hasegawa, Yuichi and Tsujita, Koji and Ono, Masayuki and Minegishi, Naoko and Hozawa, Atsushi and Murakami, Yoshinori and Kubo, Michiaki and Itonaga, Makoto and Handa, Hiroshi
Clinical Chemistry, ISSN 0009-9147, 10/2018, Volume 64, Issue 10, pp. 1463 - 1473
BACKGROUND: Although circulating exosomes in blood play crucial roles in cancer development and progression, difficulties in quantifying exosomes hamper their... 
CELLS | EXTRACELLULAR VESICLES | MARKERS | MEDICAL LABORATORY TECHNOLOGY | PROTEINS | CANCER | MODULATION | BEADS | Cell culture | Flow cytometry | CD9 antigen | Ovarian carcinoma | Surface antigens | Colorectal cancer | Antibodies | CD147 antigen | Exosomes | Ovarian cancer | Proteins | Carcinoembryonic antigen | Epidermal growth factor | Optical properties | Labeling | Growth factors | Enzyme-linked immunosorbent assay | Antigens | Immunoglobulins | CD63 antigen | Cloning | Breast cancer | Roles | Patients | ErbB-2 protein | Disk drives | Blood circulation | Linearity | MicroRNAs | Methods | Counting | Cancer
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Distinct Metabolic Flow Enables Large-Scale Purification of Mouse and Human Pluripotent Stem Cell-Derived Cardiomyocytes
by Tohyama, Shugo and Hattori, Fumiyuki and Sano, Motoaki and Hishiki, Takako and Nagahata, Yoshiko and Matsuura, Tomomi and Hashimoto, Hisayuki and Suzuki, Tomoyuki and Yamashita, Hiromi and Satoh, Yusuke and Egashira, Toru and Seki, Tomohisa and Muraoka, Naoto and Yamakawa, Hiroyuki and Ohgino, Yasuyuki and Tanaka, Tomofumi and Yoichi, Masatoshi and Yuasa, Shinsuke and Murata, Mitsushige and Suematsu, Makoto and Fukuda, Keiichi
Cell Stem Cell, ISSN 1934-5909, 01/2013, Volume 12, Issue 1, pp. 127 - 137
Heart disease remains a major cause of death despite advances in medical technology. Heart-regenerative therapy that uses pluripotent stem cells (PSCs) is a... 
HEARTS | LACTATE | MUSCLE | DIFFERENTIATION | FETAL | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Mice | Animals | Pluripotent Stem Cells - cytology | Myocytes, Cardiac - cytology | Cell Culture Techniques - methods | Humans
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
by Tomohiro Suhara and Takako Hishiki and Masataka Kasahara and Noriyo Hayakawa and Tomoko Oyaizu and Tsuyoshi Nakanishi and Akiko Kubo and Hiroshi Morisaki and William G. Kaelin and Makoto Suematsu and Yoji Andrew Minamishima
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2015, Volume 112, Issue 37, pp. 11642 - 11647
Loss of prolyl hydroxylase 2 (PHD2) activates the hypoxia-inducible factor-dependent hypoxic response, including anaerobic glycolysis, which causes large... 
Hyperlactatemia | Sepsis | PHD inhibitor | Hypoxic response | Gluconeogenesis | hyperlactatemia | MYOCARDIAL-INFARCTION | HIF | MULTIDISCIPLINARY SCIENCES | MOUSE | HYPOXIA | gluconeogenesis | FAMILY | INACTIVATION | hypoxic response | METABOLISM | LACTATE | DISEASE | SEPTIC SHOCK | sepsis | Liver - metabolism | Mice, Inbred C57BL | Blood Gas Analysis | Genotype | Male | Hepatocytes - metabolism | Oxygen - metabolism | Hypoxia - metabolism | Mice, Knockout | Animals | Lactates - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Hypoxia-Inducible Factor-Proline Dioxygenases - metabolism | Sepsis - metabolism | Acidosis, Lactic - metabolism | Mice | Blood Glucose - metabolism | Physical Conditioning, Animal | Physiological aspects | Hydroxylases | Acidosis | Health aspects | Liver | Biological Sciences
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Myocardial fatty acid uptake through CD36 is indispensable for sufficient bioenergetic metabolism to prevent progression of pressure overload-induced heart failure
by Umbarawan, Yogi and Syamsunarno, Mas Rizky A. A and Koitabashi, Norimichi and Obinata, Hideru and Yamaguchi, Aiko and Hanaoka, Hirofumi and Hishiki, Takako and Hayakawa, Noriyo and Sano, Motoaki and Sunaga, Hiroaki and Matsui, Hiroki and Tsushima, Yoshito and Suematsu, Makoto and Kurabayashi, Masahiko and Iso, Tatsuya
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 12035 - 13
The energy metabolism of the failing heart is characterized by reduced fatty acid (FA) oxidation and an increase in glucose utilization. However, little is... 
MULTIDISCIPLINARY SCIENCES | DISEASE | GROWTH | CARDIAC DYSFUNCTION | MECHANISMS | ANAPLEROSIS | ABSORPTION | EXPRESSION | DEFICIENCY | CARDIOMYOCYTE-SPECIFIC ABLATION | CYCLE | Heart failure | Tricarboxylic acid cycle | Energy metabolism | Contractility | CD36 antigen | Metabolism | Pressure | Fatty acids | Muscle contraction | Glucose metabolism | Clonal deletion | Fibrosis | Glycolysis | Aorta | Oxidation | Heart diseases | Hypertrophy
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Biochemical, metabolomic, and genetic analyses of dephospho coenzyme a kinase involved in coenzyme a biosynthesis in the human enteric parasite entamoeba histolytica
by Nurkanto, Arif and Jeelani, Ghulam and Yamamoto, Takehiro and Hishiki, Takako and Naito, Yoshiko and Suematsu, Makoto and Hashimoto, Tetsuo and Nozaki, Tomoyoshi
Frontiers in Microbiology, ISSN 1664-302X, 11/2018, Volume 9, p. 2902
Coenzyme A (CoA) is an essential cofactor for numerous cellular reactions in all living organisms. In the protozoan parasite Entamoeba histolytica, CoA is... 
Metabolome | Gene silencing | Coenzyme A | Entamoeba histolytica | Drug development | TARGET | PURINE | CRYSTAL-STRUCTURE | gene silencing | drug development | MICROBIOLOGY | IDENTIFICATION | DISCOVERY | coenzyme A | NUCLEOSIDE | ERYTHROCYTES | PLASMODIUM-FALCIPARUM | SEQUENCE ALIGNMENT | METRONIDAZOLE | metabolome
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text The histone 3 lysine 9 methyltransferase inhibitor chaetocin improves prognosis in a rat model of high salt diet-induced heart failure
by Ono, Tomohiko and Kamimura, Naomi and Matsuhashi, Tomohiro and Nagai, Toshihiro and Nishiyama, Takahiko and Endo, Jin and Hishiki, Takako and Nakanishi, Tsuyoshi and Shimizu, Noriaki and Tanaka, Hirotoshi and Ohta, Shigeo and Suematsu, Makoto and Ieda, Masaki and Sano, Motoaki and Fukuda, Keiichi and Kaneda, Ruri
Scientific Reports, ISSN 2045-2322, 01/2017, Volume 7, Issue 1, p. 39752
Histone acetylation has been linked to cardiac hypertrophy and heart failure. However, the pathological implications of changes in histone methylation and the... 
CARVEDILOL | METHYLATION | MULTIDISCIPLINARY SCIENCES | CARDIAC-HYPERTROPHY | GENE-EXPRESSION | HDAC INHIBITION | GENECODIS | DEACETYLASES | DILATED CARDIOMYOPATHY | IDENTIFICATION | ENRICHMENT ANALYSIS | RNA, Small Interfering - genetics | Prognosis | Humans | Cardiomegaly - drug therapy | Rats | Male | Nuclear Proteins - metabolism | Piperazines - therapeutic use | Transcription Factors - genetics | Rats, Sprague-Dawley | Heart Failure - drug therapy | Transcription Factors - metabolism | Histone-Lysine N-Methyltransferase - antagonists & inhibitors | Animals | Cardiomegaly - diagnosis | Cardiomegaly - chemically induced | Heart Failure - diagnosis | Acetylation | Diet Therapy | Nuclear Proteins - genetics | Chronic Disease | Sodium Chloride - metabolism | Heart Failure - chemically induced | Heart failure | Gene silencing | Mitochondria | Lysine | Medical prognosis | Rodents | Histone methyltransferase | Methylation | Heart diseases | Hypertrophy
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights