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npj Schizophrenia, ISSN 2334-265X, 12/2019, Volume 5, Issue 1, pp. 4 - 7
The accelerated aging hypothesis of schizophrenia (SCZ) has been proposed. DNA methylation profiles were developed for determining "epigenetic age." Here, we... 
DNA methylation | Schizophrenia | Epigenetics
Journal Article
Alzheimer's Research & Therapy, ISSN 1758-9193, 12/2019, Volume 11, Issue 1, pp. 1 - 15
Background Synaptic damage precedes neuron death in Alzheimer’s disease (AD). Neurexins, NRXN1, NRXN2, and NRXN3, are presynaptic adhesion molecules that... 
Haplotypes | Brain | Neurons | Cognitive ability | Genomes | Gene expression | Cell adhesion & migration | Proteins | Epidermal growth factor | Biomarkers | Aging | Age | Dementia | Alternative splicing | Alzheimer’s disease | Apolipoprotein E | Neurexins | Endocannabinoids
Journal Article
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 09/2019
Suicide is a significant public health problem worldwide, and several Asian countries including Japan have relatively high suicide rates on a world scale.... 
Journal Article
Journal Article
NEUROPSYCHIATRIC DISEASE AND TREATMENT, ISSN 1178-2021, 2019, Volume 15, pp. 2353 - 2363
Purpose: Whole-exome sequencing (WES) of multiplex families is a promising strategy for identifying causative variations for common diseases. To identify rare... 
ASSOCIATION ANALYSIS | VARIANTS | next-generation sequencing | PSYCHIATRY | IDENTIFIES 30 | Japanese | recessive variations | GENOME | CLINICAL NEUROLOGY | GENETIC-VARIATION | MUTATIONS | BURDEN | multiplex schizophrenia family
Journal Article
Psychiatry Research, ISSN 0165-1781, 08/2019, Volume 278, pp. 141 - 145
A recent genome-wide association study (GWAS) for major depressive disorder (MDD) in Chinese women identified a single-nucleotide polymorphism (SNP),... 
Rs4746720 | DNAJC12 | SNP | Postmortem brain | Rs12415800 | RNA | PSYCHIATRY | GENE-EXPRESSION | Women | Medical colleges | Anopheles | Genes | Genomics | Single nucleotide polymorphisms | Suicide | Gene expression | Major depressive disorder | Risk factors
Journal Article
Alzheimer's research & therapy, ISSN 1758-9193, 05/2019, Volume 11, Issue 1, pp. 39 - 39
Following publication of the original article [1], the authors reported that Fig. 6 contains a mistake. The Fig. 6F is a duplicate of Fig. 6E of Braak 5. 
Neurons | Alzheimer's disease | Genetic aspects
Journal Article
Alzheimer's Research and Therapy, ISSN 1758-9193, 03/2019, Volume 11, Issue 1, pp. 28 - 28
Journal Article
Journal of Psychiatric Research, ISSN 0022-3956, 02/2019, Volume 109, pp. 27 - 32
Heavy drinking leads to premature aging and precipitates the onset of age-related diseases. Acetaldehyde (AcH), a toxic metabolite of ethanol, has been... 
Alcohol dependence | Premature aging | Telomere length | ALDH2 | Age-related disease | Thiamine/vitamin B1 deficiency | OXIDATIVE STRESS | GENETIC-POLYMORPHISM | PSYCHIATRY | MITOCHONDRIAL ALDEHYDE DEHYDROGENASE | DNA-DAMAGE | RISK | CANCER | DEFICIENCY | METABOLISM | CONSUMPTION | BLOOD
Journal Article
EUROPEAN NEUROPSYCHOPHARMACOLOGY, ISSN 0924-977X, 2019, Volume 29, pp. S863 - S864
Short Telomere Length (TL) and mitochondrial DNA copy number (mtDNAcn) alterations in individuals under psychological stress, and with various psychiatric... 
PHARMACOLOGY & PHARMACY | PSYCHIATRY | NEUROSCIENCES | CLINICAL NEUROLOGY | Medical research | Telomeres | Genetic research | Medicine, Experimental | Mitochondrial DNA | Suicide | Stress (Psychology) | Mental illness
Conference Proceeding
European Neuropsychopharmacology, ISSN 0924-977X, 2019, Volume 29, pp. S863 - S864
Journal Article
Journal of pharmaceutical health care and sciences, ISSN 2055-0294, 2018, Volume 4, Issue 1, pp. 28 - 28
Risperidone is mainly metabolized by cytochrome P450 (CYP) 2D6 in the liver. The gene encoding is highly polymorphic. The average steady-state plasma... 
Symptomatology | Analysis | Schizophrenia | Dosage and administration | Genetic aspects | Research | Risperidone | Drug therapy | Genetic polymorphisms | Cytochrome | Studies | Psychotropic drugs | Plasma | Enzymes | Mental disorders | Population | Patients | Psychiatry | Drug dosages | Quality of life | Extrapyramidal symptoms | CYP2D6 | DIEPSS
Journal Article
Journal of psychiatric research, 11/2018, Volume 109, p. 27
Heavy drinking leads to premature aging and precipitates the onset of age-related diseases. Acetaldehyde (AcH), a toxic metabolite of ethanol, has been... 
Journal Article
Psychiatry Research, ISSN 0165-1781, 11/2018, Volume 269, pp. 115 - 117
Numerous evidence indicated mitochondrial abnormalities in the pathophysiology of bipolar disorder (BD); however, it remains unclear whether aberrant... 
Bipolar disorder (BD) | Mitochondria | Meta-analysis | STRESS | PSYCHIATRY | Gene Dosage - genetics | DNA, Mitochondrial - genetics | Humans | Female | Male | Biomarkers - blood | Bipolar Disorder - genetics | Bipolar Disorder - blood | Medical research | Analysis | Genetic research | Medicine, Experimental | Bipolar disorder | Mitochondrial DNA | College teachers | Index Medicus
Journal Article
Neuropsychiatric Disease and Treatment, ISSN 1176-6328, 2018, Volume 14, pp. 2115 - 2122
Journal Article
Journal Article