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Journal Article
Journal of Medical Genetics, ISSN 0022-2593, 06/2012, Volume 49, Issue 6, pp. 353 - 361
Journal Article
Journal Article
Nature Chemistry, ISSN 1755-4330, 04/2016, Volume 8, Issue 4, pp. 317 - 325
In ribosomal polypeptide synthesis the library of amino acid building blocks is limited by the manner in which codons are used. Of the proteinogenic amino... 
GENETIC-CODE | DE-NOVO | MACROCYCLIC PEPTIDES | STRUCTURAL BASIS | ESCHERICHIA-COLI | IN-VITRO SELECTION | TRANSFER-RNA | TRANSLATION | PROTEIN-SYNTHESIS | CHEMISTRY, MULTIDISCIPLINARY | CYCLIC-PEPTIDES | Amino Acid Sequence | Amino Acids - metabolism | Protein Biosynthesis | Codon | Base Sequence | Molecular Sequence Data | RNA, Transfer - genetics
Journal Article
by Ogura, K and Sato, T and Tuki, H and Honma, T
SCIENTIFIC REPORTS, ISSN 2045-2322, 08/2019, Volume 9, Issue 1, pp. 12220 - 12
Assessing the hERG liability in the early stages of drug discovery programs is important. The recent increase of hERG-related information in public databases... 
READ-ACROSS | DRUG | BLOCKERS | QSAR | MULTIDISCIPLINARY SCIENCES | COMPOUND | CLASSIFICATION MODELS | ADMET EVALUATION | PREDICTION | FEATURES | Learning algorithms | Databases | Prediction models | Classification
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2009, Volume 124, Issue 4, pp. 779 - 785.e6
Background NLR family, pyrin domain containing 3 (NLRP3), controls the activity of inflammatory caspase-1 by forming inflammasomes, which leads to cleavage of... 
Allergy and Immunology | hypersensitivity | association study | gene polymorphism | aspirin-induced asthma | anaphylaxis | food allergy | enhancer activity | NLR family, pyrin domain containing 3 | mRNA stability | NLR family | IMMUNITY | DANGER | DERMATITIS | INNATE | RISK | IMMUNOLOGY | ALLERGY | EXERCISE-INDUCED ANAPHYLAXIS | DISEASE | INFLAMMASOME | PEANUT ALLERGY | pyrin domain containing 3 | Gene Frequency - genetics | Drug Hypersensitivity - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Child, Preschool | Infant | Male | Haplotypes - genetics | Food Hypersensitivity - immunology | Aspirin - adverse effects | Drug Hypersensitivity - genetics | Anaphylaxis - immunology | Female | Child | Food Hypersensitivity - genetics | Food Hypersensitivity - metabolism | Genetic Predisposition to Disease | Introns - genetics | Exons - genetics | Genotype | Anaphylaxis - genetics | Carrier Proteins - genetics | Carrier Proteins - metabolism | Drug Hypersensitivity - immunology | Alleles | Polymorphism, Single Nucleotide | Anaphylaxis - metabolism | Medical colleges | Genetic aspects | Disease susceptibility | Public health | Asthma | Studies | Haplotypes | Food allergies | Aspirin | Hospitals | Autoimmune diseases | Allergies | Viral infections | Immune system | Food | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 03/2017, Volume 7, Issue 1, p. 45010
Scleraxis (Scx) is a basic helix-loop-helix transcription factor that is expressed persistently in tendons/ligaments, but transiently in entheseal cartilage.... 
PROGENITOR CELLS | STEM-CELLS | GENE | MOUSE EMBRYOGENESIS | TENDON DIFFERENTIATION | MULTIDISCIPLINARY SCIENCES | GENERATION | BONE | TENOMODULIN | EXPRESSION | CHONDROMODULIN-I | Phosphorylation | Integration | Sox9 protein | Rib | Smad3 protein | Recombinase | Cre recombinase | Tendons | Homozygotes | Cartilage | Musculoskeletal system | Patella | Rodents | Calcaneus | Helix-loop-helix proteins | Ligaments
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 135, Issue 6, pp. 1538 - 1545.e17
Background Stevens-Johnson syndrome (SJS) and its severe form, toxic epidermal necrolysis (TEN), are acute inflammatory vesiculobullous reactions of the skin... 
Allergy and Immunology | Stevens-Johnson syndrome | alternative splicing | severe mucosal involvement | genome-wide association study | cold medicine | IKZF1 | toxic epidermal necrolysis | ERYTHEMA MULTIFORME | POPULATION | OCULAR SURFACE COMPLICATIONS | DNA-BINDING PROTEINS | RISK | IMMUNOLOGY | IKAROS GENE | POLYMORPHISMS | ALLERGY | IKZFl | DRUGS | JAPANESE | GENOME-WIDE ASSOCIATION | Alternative Splicing | Humans | Middle Aged | Male | Genetic Loci | Case-Control Studies | Ikaros Transcription Factor - genetics | Mouth Mucosa - drug effects | Multi-Ingredient Cold, Flu, and Allergy Medications - adverse effects | Stevens-Johnson Syndrome - ethnology | Adult | Female | Mouth Mucosa - pathology | Odds Ratio | Genetic Predisposition to Disease | Genome-Wide Association Study | Stevens-Johnson Syndrome - etiology | European Continental Ancestry Group | Asian Continental Ancestry Group | HLA-A Antigens - immunology | Stevens-Johnson Syndrome - genetics | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Ikaros Transcription Factor - immunology | Adolescent | HLA-A Antigens - genetics | Aged | Polymorphism, Single Nucleotide | Protein Isoforms - immunology | Stevens-Johnson Syndrome - pathology | Protein Isoforms - genetics | Medical colleges | Pharmacogenetics | Genetic research | Respiratory agents | Disease susceptibility | Genetic aspects | Ophthalmology | Pharmaceutical industry | Medicine | Medical personnel | Genotype & phenotype | Medical treatment | Mortality | Colleges & universities | Quality control | Genomes | Nonsteroidal anti-inflammatory drugs
Journal Article