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Cell, ISSN 0092-8674, 11/2013, Volume 155, Issue 4, p. 934
Summary Super-enhancers are large clusters of transcriptional enhancers that drive expression of genes that define cell identity. Improved understanding of the... 
Journal Article
SCIENCE, ISSN 0036-8075, 07/2018, Volume 361, Issue 6400, p. 379
Super-enhancers (SEs) are clusters of enhancers that cooperatively assemble a high density of the transcriptional apparatus to drive robust expression of genes... 
RNA-POLYMERASE-II | INTRINSIC DISORDER | PROTEIN | MULTIDISCIPLINARY SCIENCES | CELL IDENTITY | LIQUID DROPLETS | PLURIPOTENCY | TRANSITIONS | BINDING | TRANSCRIPTIONAL ELONGATION | P-TEFB | Embryonic Stem Cells - metabolism | NIH 3T3 Cells | Immunoprecipitation | Transcription Factors - chemistry | Fluorescence Recovery After Photobleaching | Humans | Molecular Imaging | Trans-Activators - chemistry | Cell Nucleus - metabolism | HEK293 Cells | Trans-Activators - genetics | Conserved Sequence | Nuclear Proteins - genetics | Mediator Complex Subunit 1 - chemistry | Mediator Complex Subunit 1 - metabolism | Serine - genetics | Nuclear Proteins - metabolism | Transcription Factors - genetics | Nuclear Proteins - chemistry | Serine - chemistry | Intrinsically Disordered Proteins - genetics | Enhancer Elements, Genetic - drug effects | Glycols - pharmacology | Gene Expression Regulation - drug effects | Transcription Factors - metabolism | Animals | Intrinsically Disordered Proteins - chemistry | Trans-Activators - metabolism | Mice | Cell Nucleus - drug effects | Mediator Complex Subunit 1 - genetics | Intrinsically Disordered Proteins - metabolism | Genetic research | Transcription factors | Genetic aspects | Research | Mammals | Chromatin | Nucleation | Transcription elongation | Genes | Gene regulation | Embryo cells | Fluorescence | Stem cell transplantation | Density | DNA-directed RNA polymerase | Cofactors | Complexity | Proteins | Nucleoli | Condensates | Clusters | Droplets | Hubs | Elongation | Deoxyribonucleic acid--DNA | Photobleaching | Collapsing | Pol II | Amino acid sequence | Gene expression | Molecular chains | Polymerase | Organic chemistry | Enhancers | Properties (attributes) | Sensitivity | Inhibitors | Ribonucleic acids | Phase separation | Stem cells | Nuclei (cytology) | Protein interaction | Transcription initiation | Nuclear reactions | Cancer
Journal Article
Nature Genetics, ISSN 1061-4036, 10/2016, Volume 48, Issue 10, pp. 1253 - 1259
Journal Article
PLoS Pathogens, ISSN 1553-7366, 05/2010, Volume 6, Issue 5, pp. 1 - 18
Candida albicans, like other pleiomorphic fungal pathogens, is able to undergo a reversible transition between single yeast-like cells and multicellular... 
GENETIC-ANALYSIS | DEPENDENT PROTEIN-KINASE | MICROBIOLOGY | LARGE-SCALE | FUNGAL MORPHOGENESIS | SACCHAROMYCES-CEREVISIAE | HYPHAL FORMATION | VIROLOGY | OPAQUE-PHASE | FILAMENTOUS GROWTH | CRYPTOCOCCUS-NEOFORMANS | PARASITOLOGY | WHITE-PHASE | Saccharomyces cerevisiae - genetics | Virulence | Male | Candidiasis - microbiology | Candida albicans - genetics | Epistasis, Genetic - physiology | Gene Expression Regulation, Fungal - physiology | Cyclic AMP - metabolism | Candida albicans - pathogenicity | Cyclic AMP-Dependent Protein Kinases - metabolism | Carbon - metabolism | Histone Deacetylases - genetics | Histone Deacetylases - metabolism | Adenine - pharmacology | Fungal Proteins - genetics | Saccharomyces cerevisiae Proteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Homozygote | Phenotype | Animals | Signal Transduction - drug effects | Saccharomyces cerevisiae Proteins - metabolism | Saccharomyces cerevisiae - enzymology | Hyphae - drug effects | Signal Transduction - physiology | Mice | Mice, Inbred BALB C | Candida albicans - enzymology | Fungal Proteins - metabolism | Hyphae - physiology | Candida albicans | Physiological aspects | Genetic aspects | Cyclic adenylic acid | Research | Virulence (Microbiology) | Protein kinases | Protein kinase A | Histone deacetylase | Pathogens | Animal models | Chromatin | Disseminated infection | Cyclic AMP | virulence factors | Fungi | Morphogenesis | Signal transduction | Repressors | Filaments | Evolution | Filamentation | Nutrients | Trichostatin A | Drug discovery | Immune system | Proteins | Infections | Kinases
Journal Article