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by Verhoeven, Virginie J. M and Hysi, Pirro G and Wojciechowski, Robert and Fan, Qiao and Guggenheim, Jeremy A and Höhn, René and Macgregor, Stuart and Hewitt, Alex W and Nag, Abhishek and Cheng, Ching-Yu and Yonova-Doing, Ekaterina and Zhou, Xin and Ikram, M. Kamran and Buitendijk, Gabriëlle H. S and McMahon, George and Kemp, John P and Pourcain, Beate St and Simpson, Claire L and Mäkelä, Kari-Matti and Lehtimäki, Terho and Kähönen, Mika and Paterson, Anew D and Hosseini, S. Mohsen and Wong, Hoi Suen and Xu, Liang and Jonas, Jost B and Pärssinen, Olavi and Wedenoja, Juho and Yip, Shea Ping and Ho, Daniel W. H and Pang, Chi Pui and Chen, Li Jia and Burdon, Kathryn P and Craig, Jamie E and Klein, Barbara E. K and Klein, Ronald and Haller, Toomas and Metspalu, Anes and Khor, Chiea-Chuen and Tai, E.-Shyong and Aung, Tin and Vithana, Eranga and Tay, Wan-Ting and Barathi, Veluchamy A and Chen, Peng and Li, Ruoying and Liao, Jiemin and Zheng, Yingfeng and Ong, Rick T and Döring, Angela and Evans, David M and Timpson, Nicholas J and Verkerk, Annemieke J. M. H and Meitinger, Thomas and Raitakari, Olli and Hawthorne, Felicia and Spector, Tim D and Karssen, Lennart C and Pirastu, Mario and Murgia, Federico and Ang, Wei and Mishra, Aniket and Montgomery, Grant W and Pennell, Craig E and Cumberland, Phillippa M and Cotlarciuc, Ioana and Mitchell, Paul and Wang, Jie Jin and Schache, Maria and Janmahasathian, Sarayut and Igo, Robert P and Lass, Jonathan H and Chew, Emily and Iyengar, Sudha K and Gorgels, Theo G. M. F and Rudan, Igor and Hayward, Caroline and Wright, Alan F and Polasek, Ozren and Vatavuk, Zoran and Wilson, James F and Fleck, Brian and Zeller, Tanja and Mirshahi, Alireza and Müller, Christian and Uitterlinden, Ané G and Rivadeneira, Fernando and Vingerling, Johannes R and Hofman, Albert and Oostra, Ben A and Amin, Najaf and Bergen, Arthur A. B and teo, Yik-Ying and Rahi, Jugnoo S and Vitart, Veronique and Williams, Cathy and Baird, Paul N and Wong, Tien-Yin and Oexle, Konrad and Pfeiffer, Norbert and ... and Fuchs' Genetics Multi-Ctr Study Gr and Diabet Control Complications Trial and WTCCC2 and CREAM and Consortium for Refractive Error and Myopia (CREAM) and Fuchs' Genetics Multi-Center Study Group and Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group and Wellcome Trust Case Control Consortium 2 (WTCCC2) and The Fuchs' Genetics Multi-Center Study Group and The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group
Nature genetics, ISSN 1061-4036, 2013, Volume 45, Issue 3, pp. 314 - 318
Journal Article
by Cheng, Ching-Yu and Schache, Maria and Ikram, M. Kamran and Ikram, M. Kamran and Young, Terri L and Young, Terri L and Guggenheim, Jeremy A and Guggenheim, Jeremy A and Vitart, Veronique and MacGregor, Stuart and Verhoeven, Virginie J.M and Verhoeven, Virginie J.M and Barathi, Veluchamy A and Liao, Jiemin and Hysi, Pirro G and Hysi, Pirro G and Bailey-Wilson, Joan E and St. Pourcain, Beate and Kemp, John P and McMahon, George and Timpson, Nicholas J and Evans, David M and Montgomery, Grant W and Mishra, Aniket and Wang, Jie Jin and Wang, Jie Jin and Wang, Ya Xing and Rochtchina, Elena and Polasek, Ozren and Wright, Alan F and Wright, Alan F and Amin, Najaf and van Leeuwen, Elisabeth M and Wilson, James F and Wilson, James F and Wilson, Joan E. Bailey and Pennell, Craig E and van Duijn, Cornelia M and de Jong, Paulus T.V.M and Vingerling, Johannes R and Zhou, Xin and Zhou, Xiangtian and Chen, Peng and Chen, Li Jia and Chen, Wei and Li, Ruoying and Tay, Wan-Ting and Zheng, Yingfeng and Zheng, D and Chew, Merwyn and Chew, Emily Y and Chew, Emily and Rahi, Jugnoo S and Yoshimura, Nagahisa and Yamashiro, Kenji and Miyake, Masahiro and Delcourt, Cécile and Maubaret, Cecilia and Williams, T and Williams, Katie M and Williams, Cathy and Northstone, Kate and Ring, Susan M and Davey-Smith, George and Craig, Jamie E and Burdon, Kathryn P and Fogarty, Rhys D and Iyengar, Sudha K and Igo, Robert P and Janmahasathian, Sarayut and Stambolian, Dwight and Lu, Yi and Jonas, Jost B and Xu, Liang and Saw, Seang-Mei and Baird, Paul N and Mitchell, Paul and Nangia, Vinay and Hayward, Caroline and Campbell, C and Campbell, Harry and Rudan, Igor and Vatavuk, Zoran and Paterson, Andrew D and Hosseini, S. Mohsen and Fondran, Jeremy R and Feng, Sheng and Klaver, Caroline C and Klaver, Caroline C.W and van Duijn, Cornelia M and Metspalu, Andres and Haller, Toomas and Mihailov, Evelin and Pärssinen, Olavi and Wedenoja, Juho and Wojciechowski, Robert and Pfeiffer, Norbert and Höhn, René and Pang, Chi Pui and Meitinger, Thomas and ... and Consortium Refractive Error Myopia and Fuchs Genetics Multictr Study Grp and Diabet Control Complications Trial and Wellcome Trust Case Control Consor and Fuchs' Genetics Multi-Center Study Group and Consortium for Refractive Error and Myopia and Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions, and Complications Research Group and Wellcome Trust Case Control Consortium 2
The American Journal of Human Genetics, ISSN 0002-9297, 08/2013, Volume 93, Issue 2, pp. 264 - 277
Journal Article
Journal Article
Gut, ISSN 0017-5749, 08/2017, Volume 66, Issue 8, pp. 1496 - 1506
ObjectiveWe investigated the mutational landscape of mammalian target of rapamycin (mTOR) signalling cascade in hepatocellular carcinomas (HCCs) with chronic... 
HEPATITIS B | GENE MUTATION | MUTATION SCREENING | HEPATOCELLULAR CARCINOMA | THERAPEUTIC TARGETS | HEPATOCELLULAR-CARCINOMA | MTORC1 | MICE | GASTROENTEROLOGY & HEPATOLOGY | PATHWAY | Neoplasm Transplantation | Antibiotics, Antineoplastic - pharmacology | Axin Protein - genetics | TOR Serine-Threonine Kinases - metabolism | Humans | Middle Aged | Male | Liver Neoplasms - chemistry | Tumor Suppressor Protein p53 - genetics | Young Adult | DNA Mutational Analysis | Carcinoma, Hepatocellular - genetics | Tumor Suppressor Proteins - genetics | Adult | Female | Carcinoma, Hepatocellular - chemistry | Nuclear Proteins - genetics | Tumor Stem Cell Assay | Cell Proliferation - genetics | Sirolimus - therapeutic use | Liver Neoplasms - genetics | Signal Transduction | Mutation Rate | Transcription Factors - genetics | Sirolimus - pharmacology | beta Catenin - genetics | Animals | Antibiotics, Antineoplastic - therapeutic use | Liver Neoplasms - metabolism | Cell Line, Tumor | Aged | Cell Proliferation - drug effects | Mice | Carcinoma, Hepatocellular - metabolism | Tumor Suppressor Proteins - analysis | Reports | Care and treatment | Hepatoma | Research | Gene mutations | TOR protein | Tuberous sclerosis 2 protein | Immunohistochemistry | Hepatocellular carcinoma | Hamartin | Infections | Genomes | Insulin-like growth factors | Kinases | TSC1 protein | Cancer therapies | Sclerosis | Liver cancer | Signal transduction | Epidermal growth factor | Next-generation sequencing | Gastroenterology | Xenografts | Aggressive behavior | Colonies | Hypersensitivity | Tuberous sclerosis | Rapamycin | FDA approval | Patients | TSC2 protein | Cell lines | Ligands | Mutation | Tumors | Index Medicus | Abridged Index Medicus | 1506 | Hepatology
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 11/2013, Volume 123, Issue 11, pp. 4909 - 4917
Journal Article