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European Journal of Pharmacology, ISSN 0014-2999, 11/2016, Volume 791, p. 659
The present study investigates the effect of commonly used negative and positive allosteric modulators of the calcium-sensing receptor (CaSR) on vascular... 
Endothelium
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 06/2010, Volume 160, Issue 3, pp. 594 - 603
Background and purpose:  N-arachidonoyl glycine (NAGly) is an endogenous lipid that is structurally similar to the endocannabinoid, N-arachidonoyl ethanolamide... 
endothelium | N-arachidonoyl γ-aminobutyric acid | nitric oxide | potassium channels | N-arachidonoyl serine | rat mesenteric artery | cannabinoid receptor | N-arachidonoyl glycine | TRPV1 receptor | arachidonoyl serine | arachidonoyl γ‐aminobutyric acid | arachidonoyl glycine | Cannabinoid receptor | Nitric oxide | Rat mesenteric artery | Potassium channels | Endothelium | CELLS | ANANDAMIDE-INDUCED VASORELAXATION | BRAIN CONSTITUENT | N-arachidonoyl gamma-aminobutyric acid | CA2+-ACTIVATED K+ CHANNELS | L-SERINE | MESENTERIC-ARTERY | IDENTIFICATION | ARACHIDONYLGLYCINE | METABOLISM | PHARMACOLOGY & PHARMACY | Large-Conductance Calcium-Activated Potassium Channels | Glycine - analogs & derivatives | Mesenteric Arteries - physiology | Rats, Wistar | Endothelium, Vascular - drug effects | Male | Mesenteric Arteries - drug effects | Endothelium, Vascular - physiology | Drug Interactions | Vasodilation - physiology | Pertussis Toxin - pharmacology | Arachidonic Acids - physiology | NG-Nitroarginine Methyl Ester - pharmacology | Serine - analogs & derivatives | Rats | gamma-Aminobutyric Acid - pharmacology | Nitric Oxide - physiology | Arachidonic Acids - pharmacology | Peptides - pharmacology | Animals | Arachidonic Acids - antagonists & inhibitors | Glycine - antagonists & inhibitors | Glycine - pharmacology | Glycine - physiology | Serine - pharmacology | Vasodilation - drug effects | gamma-Aminobutyric Acid - analogs & derivatives | Index Medicus | Research Papers
Journal Article
Neuropharmacology, ISSN 0028-3908, 01/2008, Volume 54, Issue 1, pp. 108 - 116
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 02/2011, Volume 162, Issue 3, pp. 749 - 762
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 02/2011, Volume 162, Issue 3, pp. 749 - 762
BACKGROUND AND PURPOSE The calcimimetic, (R)-N-(3-(3-(trifluoromethyl)phenyl)propyl)-1-(1-napthyl)ethylamine hydrochloride (cinacalcet), which activates... 
GPRC6A | endothelium | cinacalcet | calhex 231 | 2 | influx | L‐ornithine | calindol | mesenteric arteries | calcimimetics | Ca | sensing receptors | L-ornithine | 2-ARACHIDONOYLGLYCEROL | ANANDAMIDE | BLOOD-PRESSURE | CALCIUM-SENSING RECEPTOR | ISOLATED MESENTERIC-ARTERY | PHARMACOKINETICS | CINACALCET HCL | RENAL-FAILURE | PHARMACOLOGY & PHARMACY | SMOOTH-MUSCLE-CELLS | CA2+-INDUCED RELAXATION | Ca2+-sensing receptors | Ca2+influx | Mesenteric Arteries - physiology | Muscle, Smooth, Vascular - metabolism | Rats, Wistar | Calcium - metabolism | Stereoisomerism | Male | Mesenteric Arteries - drug effects | Receptors, Calcium-Sensing - metabolism | Potassium Channels - metabolism | Calcimimetic Agents - pharmacology | Indoles - pharmacology | Mesenteric Veins - drug effects | Muscle, Smooth, Vascular - drug effects | Vasodilator Agents - pharmacology | Ornithine - pharmacology | 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester - pharmacology | Rats | Naphthalenes - pharmacology | Cinacalcet Hydrochloride | Animals | Ionomycin - pharmacology | Mesenteric Arteries - innervation | Calcium Channels, L-Type - metabolism | Endothelial Cells - drug effects | Mesenteric Veins - physiology | Calcium channels | Ionomycin | Calcium | Capsaicin | Smooth muscle | Potassium channels | Arteries | Calcium influx | Endothelial cells | Endothelium | Potassium channels (calcium-gated) | Calcium channels (L-type) | Sensory neurons | Parathyroid | Calcium-sensing receptors | Hyperparathyroidism | Index Medicus | Research Papers | Ca2+ influx
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 06/2010, Volume 160, Issue 3, pp. 594 - 603
Journal Article
Vascular Pharmacology, ISSN 1537-1891, 09/2017, Volume 96-98, pp. 53 - 62
Stimulation of calcium-sensing receptors (CaSR) by increasing the external calcium concentration (Ca ] ) induces endothelium-dependent vasorelaxation through... 
IKCA CHANNELS | OPERATED CA2+ ENTRY | TRPV4 CHANNELS | ENDOTHELIUM-DEPENDENT HYPERPOLARIZATION | PHARMACOLOGY & PHARMACY | SMOOTH-MUSCLE-CELLS | CA2+-INDUCED RELAXATION | VASCULAR REACTIVITY | BLOOD-PRESSURE | K+ CHANNELS | CA2+-SENSING RECEPTOR | Rabbits | TRPC Cation Channels - drug effects | Vasodilator Agents - pharmacology | Endothelial Cells - metabolism | Male | TRPV Cation Channels - drug effects | Receptors, Calcium-Sensing - metabolism | Mesenteric Artery, Superior - drug effects | Dose-Response Relationship, Drug | TRPV Cation Channels - metabolism | Animals | Mesenteric Artery, Superior - metabolism | Membrane Potentials | TRPC Cation Channels - metabolism | Receptors, Calcium-Sensing - drug effects | Vasodilation - drug effects | In Vitro Techniques | Nitric Oxide - metabolism | Calcium Signaling | Endothelial Cells - drug effects | Blood vessels | Dilatation | Nitric oxide | Arteries | Proteins | Viral antibodies | Antibodies | Potassium channels | Cytochemistry | Endothelium | Calcium oxide | Calcium | Blocking antibodies | Fluorescence | Activation | Antagonists | Hormones | Vasodilation | Lime | Receptors | Ion channels | Inhibition | Chemical synthesis | Calcium channels | Channel gating | Nitric-oxide synthase | Endothelial cells | NG-Nitroarginine methyl ester | Laboratory animals | Potassium currents | Calcium-sensing receptors | Index Medicus | TRPV4, transient receptor potential vanilloid-4 | IKCa, intermediate conductance calcium-activated potassium channels | NO, nitric oxide | TRPC1, canonical transient receptor potential channel 1 | CaSR, calcium-sensing receptors | EC, endothelial cell
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 08/2017, Volume 174, Issue 16, pp. 2662 - 2681
BACKGROUND AND PURPOSE Our initial aim was to generate cannabinoid agents that control spasticity, occurring as a consequence of multiple sclerosis (MS),... 
MOLECULAR-MECHANISM | BKCA CHANNELS | VASORELAXATION | PUBLICATION | CONCISE GUIDE | PHARMACOLOGY | RECEPTOR | PHARMACOLOGY & PHARMACY | DYSFUNCTION | N-ARACHIDONOYL GLYCINE | SUBUNIT | Mesenteric Arteries - physiology | Endocannabinoids - pharmacology | Rats, Wistar | Benzamides - pharmacokinetics | Male | Mesenteric Arteries - drug effects | Hepatocytes - metabolism | Isomerism | Muscle Spasticity - drug therapy | Benzamides - therapeutic use | Large-Conductance Calcium-Activated Potassium Channels - physiology | Female | Benzamides - pharmacology | Macaca | Endocannabinoids - therapeutic use | Receptors, Cannabinoid - genetics | Vas Deferens - drug effects | Benzamides - chemistry | Endocannabinoids - pharmacokinetics | Rabbits | Double-Blind Method | Encephalomyelitis, Autoimmune, Experimental - drug therapy | Rats, Sprague-Dawley | Mice, Knockout | Animals | Receptor, Cannabinoid, CB1 - genetics | Dogs | Mice | Vas Deferens - physiology | Endocannabinoids - chemistry | Spasticity | Analysis | Potassium channels | Drug abuse | Animal models | Multiple sclerosis | Target recognition | Encephalomyelitis | Calcium | Potassium conductance | Assaying | Potassium channels (calcium-gated) | Cannabis | Receptors | Muscles | Excitability | Pharmacology | Anandamide | Resistance | Organic chemistry | Side effects | Calcium conductance | Plasma levels | Conductance | Pharmacokinetics | Potassium | Hyperpolarization | Index Medicus | Research Papers | Research Paper
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 12/2006, Volume 31, Issue 12, pp. 2591 - 2599
The efficacy of antidepressants has been linked in part to their ability to reduce activity of the hypothalamic-pituitary-adrenal (HPA) axis; however, the... 
c-fos | Depression | Norepinephrine | Swim stress | AM251 | Desipramine | norepinephrine | CORTICOTROPIN-RELEASING HORMONE | swim stress | RAT | PSYCHIATRY | ANANDAMIDE | MAJOR DEPRESSION | NEUROSCIENCES | desipramine | VENTRAL SUBICULUM | HIPPOCAMPUS | RESTRAINT STRESS | FORCED-SWIM TEST | PHARMACOLOGY & PHARMACY | depression | ANXIETY DISORDERS | RECEPTOR-ACTIVITY | Cannabinoid Receptor Modulators - metabolism | Depressive Disorder, Major - metabolism | Male | Hippocampus - drug effects | Desipramine - pharmacology | Receptor, Cannabinoid, CB1 - agonists | Piperidines - pharmacology | Stress, Psychological - metabolism | Up-Regulation - physiology | Hypothalamo-Hypophyseal System - physiopathology | Endocannabinoids | Depressive Disorder, Major - drug therapy | Disease Models, Animal | Pyrazoles - pharmacology | Depressive Disorder, Major - physiopathology | Hypothalamo-Hypophyseal System - drug effects | Drug Administration Schedule | Stress, Psychological - drug therapy | Cortisone - metabolism | Proto-Oncogene Proteins c-fos - metabolism | Cannabinoid Receptor Modulators - agonists | Gene Expression Regulation - physiology | Rats | Rats, Sprague-Dawley | Hypothalamo-Hypophyseal System - metabolism | Proto-Oncogene Proteins c-fos - drug effects | Cortisone - secretion | Gene Expression Regulation - drug effects | Up-Regulation - drug effects | Hippocampus - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Paraventricular Hypothalamic Nucleus - drug effects | Animals | Norepinephrine - metabolism | Antidepressive Agents, Tricyclic - pharmacology | Paraventricular Hypothalamic Nucleus - metabolism | Paraventricular Hypothalamic Nucleus - secretion | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Hippocampus - physiopathology | Stress, Psychological - physiopathology | Index Medicus
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 01/2009, Volume 156, Issue 1, pp. 94 - 104
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 02/2011, Volume 162, Issue 3, pp. 749 - 762
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 2003, Volume 138, Issue 7, pp. 1320 - 1332
1. The nonpsychoactive cannabinoid abnormal-cannabidiol (trans-4-[3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol) (abn-cbd) produced... 
Cannabinoids | Ionomycin | channels | Cannabinoid antagonists | Mesenteric artery (rat) | SR 141716A | Abnormal-cannabidiol | K | Ca | Pertussis toxin | Cannabinoid receptors | Calcium Channels - drug effects | Myography | Endothelium-Dependent Relaxing Factors - pharmacology | Rats, Wistar | Cannabinoid Receptor Antagonists | Bornanes - pharmacology | Rat