X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (35) 35
animals (19) 19
mice (16) 16
article (10) 10
crystallography, x-ray (10) 10
proteins (10) 10
biochemistry & molecular biology (9) 9
humans (9) 9
research (9) 9
amino acid sequence (8) 8
analysis (8) 8
apoptosis (8) 8
cell biology (8) 8
mice, knockout (8) 8
protein binding (8) 8
bacterial proteins - chemistry (7) 7
cells (7) 7
molecular sequence data (7) 7
multidisciplinary sciences (7) 7
bacteria (6) 6
bcl-2-associated x protein - metabolism (6) 6
binding sites (6) 6
biosynthesis (6) 6
c-di-gmp (6) 6
crystals (6) 6
genetic aspects (6) 6
male (6) 6
membrane proteins - metabolism (6) 6
apoptosis regulatory proteins - metabolism (5) 5
bacterial proteins - metabolism (5) 5
bcl-2 homologous antagonist-killer protein - metabolism (5) 5
bcl-2-like protein 11 (5) 5
bh3 domains (5) 5
bh3 interacting domain death agonist protein - metabolism (5) 5
binding (5) 5
biophysics (5) 5
cell-death (5) 5
clp (5) 5
female (5) 5
membrane proteins - chemistry (5) 5
models, molecular (5) 5
physiological aspects (5) 5
protein structure, tertiary (5) 5
proto-oncogene proteins - metabolism (5) 5
activation (4) 4
bcl-2 homologous antagonist-killer protein - genetics (4) 4
bh3-only proteins (4) 4
biochemical research methods (4) 4
biological phenomena, cell phenomena, and immunity (4) 4
cells, cultured (4) 4
crystal-structure (4) 4
crystallization (4) 4
crystallography (4) 4
cyclic gmp - analogs & derivatives (4) 4
cyclic gmp - metabolism (4) 4
cytochrome-c (4) 4
gene expression (4) 4
membrane proteins - genetics (4) 4
microbiology (4) 4
mitochondria - metabolism (4) 4
mitochondrial apoptosis (4) 4
models, biological (4) 4
pathogenicity (4) 4
pathogens (4) 4
protein conformation (4) 4
pseudomonas-aeruginosa (4) 4
risk factors (4) 4
sequence alignment (4) 4
structure (4) 4
transcription factors - metabolism (4) 4
tumor suppressor proteins - metabolism (4) 4
xanthomonas campestris (4) 4
apoptosis regulatory proteins - genetics (3) 3
bax (3) 3
bcl-2 family-members (3) 3
bcl-2-associated x protein - chemistry (3) 3
bcl-2-associated x protein - genetics (3) 3
bh3 interacting domain death agonist protein - genetics (3) 3
biochemistry (3) 3
biological response modifiers (3) 3
biological-control agent (3) 3
biology (3) 3
biotechnology & applied microbiology (3) 3
cancer (3) 3
cell death (3) 3
cell line, tumor (3) 3
crystallization communications (3) 3
c‐di‐gmp (3) 3
developmental biology (3) 3
escherichia-coli (3) 3
expression (3) 3
gene expression regulation, bacterial (3) 3
gene-expression (3) 3
identification (3) 3
innate immune receptors (3) 3
life sciences (3) 3
membrane permeabilization (3) 3
molecular biology (3) 3
mouse sting (3) 3
mutant proteins - chemistry (3) 3
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Science, ISSN 0036-8075, 12/2010, Volume 330, Issue 6009, pp. 1390 - 1393
Although the proteins BAX and BAK are required for initiation of apoptosis at the mitochondria, how BAX and BAK are activated remains unsettled. We provide in... 
T lymphocytes | Mitochondria | Cytokines | Thymocytes | Neurons | Cell death | REPORTS | Cytochromes | Mice | Potassium | Apoptosis | NEURONAL APOPTOSIS | CYTOCHROME-C | MITOCHONDRIAL APOPTOSIS | MECHANISM | MULTIDISCIPLINARY SCIENCES | BH3 DOMAINS | RELEASE | JNK PATHWAY | PROTEINS | BCL-2 FAMILY-MEMBERS | MEMBRANE PERMEABILIZATION | BH3 Interacting Domain Death Agonist Protein - deficiency | T-Lymphocytes - physiology | bcl-2-Associated X Protein - chemistry | Protein Multimerization | Stress, Physiological | bcl-2 Homologous Antagonist-Killer Protein - genetics | BH3 Interacting Domain Death Agonist Protein - genetics | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Membrane Proteins - deficiency | Caspases - metabolism | Bcl-2-Like Protein 11 | Apoptosis Regulatory Proteins - deficiency | Tumor Suppressor Proteins - deficiency | Tumor Suppressor Proteins - genetics | Neurons - physiology | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | bcl-2-Associated X Protein - genetics | Proto-Oncogene Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Membrane Proteins - genetics | Cytochromes c - metabolism | Cells, Cultured | bcl-2-Associated X Protein - metabolism | Proto-Oncogene Proteins - genetics | Mitochondria - metabolism | Permeability | Proto-Oncogene Proteins - deficiency | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Animals | Models, Biological | Cerebellum - cytology | Intracellular Membranes - metabolism | bcl-2 Homologous Antagonist-Killer Protein - chemistry | Protein research | Genetic aspects | Mitochondrial DNA | Biochemical genetics | Research | Properties | Methods | Index Medicus
Journal Article
Journal Article
Nature Cell Biology, ISSN 1465-7392, 10/2015, Volume 17, Issue 10, pp. 1270 - 1281
Multidomain pro-apoptotic BAX and BAK, once activated, permeabilize mitochondria to trigger apoptosis, whereas anti-apoptotic BCL-2 members preserve... 
CYTOCHROME-C | MITOCHONDRIAL APOPTOSIS | ACTIVATION | CONFORMATIONAL-CHANGE | MEMBERS | PROAPOPTOTIC BAX | BH3 DOMAINS | PUMA | BH3-ONLY PROTEINS | MEMBRANE PERMEABILIZATION | CELL BIOLOGY | bcl-2 Homologous Antagonist-Killer Protein - genetics | Immunoblotting | BH3 Interacting Domain Death Agonist Protein - genetics | Cytochromes c - genetics | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Embryo, Mammalian - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Bcl-2-Like Protein 11 | Mitochondria - genetics | RNA Interference | Tumor Suppressor Proteins - genetics | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | bcl-2-Associated X Protein - genetics | Fibroblasts - metabolism | Proto-Oncogene Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Membrane Proteins - genetics | Cytochromes c - metabolism | Mice, Inbred C57BL | Cells, Cultured | bcl-2-Associated X Protein - metabolism | Proto-Oncogene Proteins - genetics | Mitochondria - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Animals | Intestine, Small - cytology | Embryo, Mammalian - cytology | Models, Biological | Fibroblasts - cytology | Intestine, Small - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | Apoptosis | Genotype | Genetic aspects | Properties | Cell death | Cellular control mechanisms | Index Medicus
Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2009, Volume 36, Issue 3, pp. 487 - 499
While activation of BAX/BAK by BH3-only molecules (BH3s) is essential for mitochondrial apoptosis, the underlying mechanisms remain unsettled. Here we... 
CELLCYCLE | CYTOCHROME-C | PROAPOPTOTIC BAX | OLIGOMERIZES BAK | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOPLASMIC-RETICULUM | SUBCELLULAR LOCATION | PROTEINS | BCL-2 FAMILY-MEMBERS | BH3 DOMAIN | CELL-DEATH | MEMBRANE PERMEABILIZATION | CELL BIOLOGY | bcl-2-Associated X Protein - chemistry | Immunoprecipitation | Apoptosis - drug effects | Protein Multimerization | bcl-2 Homologous Antagonist-Killer Protein - genetics | Immunoblotting | BH3 Interacting Domain Death Agonist Protein - genetics | Green Fluorescent Proteins - genetics | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Bcl-2-Like Protein 11 | Protein Binding - drug effects | Tumor Suppressor Proteins - genetics | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | bcl-2-Associated X Protein - genetics | Fibroblasts - metabolism | Proto-Oncogene Proteins - metabolism | Green Fluorescent Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Membrane Proteins - genetics | Cells, Cultured | bcl-2-Associated X Protein - metabolism | Etoposide - pharmacology | Proto-Oncogene Proteins - genetics | Mitochondria - metabolism | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Animals | Models, Biological | Tunicamycin - pharmacology | Fibroblasts - drug effects | Thapsigargin - pharmacology | Fibroblasts - cytology | Mice | Mutation | Microscopy, Fluorescence | Staurosporine - pharmacology | bcl-2 Homologous Antagonist-Killer Protein - chemistry | Monomers | Apoptosis | Oligomers | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2009, Volume 106, Issue 4, pp. 1093 - 1098
Journal Article
Journal Article
Gastroenterology, ISSN 0016-5085, 04/2018, Volume 154, Issue 5, pp. 1421 - 1434
Cytokinesis can fail during normal postnatal liver development, leading to polyploid hepatocytes. We investigated whether inhibiting cytokinesis in the liver... 
Hepatic Carcinogenesis | Tumorigenesis | RNA Interference | Cell Cycle | TRANSFORMATION | PROGNOSIS | FAILURE | CANCER | RHOA | CELL-DIVISION | ANEUPLOIDY | ANLN | HEPATOCELLULAR-CARCINOMA | GASTROENTEROLOGY & HEPATOLOGY | Carcinoma, Hepatocellular - prevention & control | Humans | Hepatocytes - pathology | Hepatocytes - metabolism | Hepatectomy | Transfection | Time Factors | Cell Transformation, Neoplastic - genetics | Carcinoma, Hepatocellular - genetics | Liver Neoplasms - pathology | Microfilament Proteins - metabolism | Chemical and Drug Induced Liver Injury - pathology | Hepatocytes - transplantation | Microfilament Proteins - genetics | Liver Neoplasms - prevention & control | Cell Line | Genetic Predisposition to Disease | Liver Regeneration | Microfilament Proteins - deficiency | Liver Neoplasms - genetics | Chemical and Drug Induced Liver Injury - genetics | Cytokinesis | Cell Transformation, Neoplastic - metabolism | Proto-Oncogene Proteins c-myc - metabolism | Mice, Knockout | Carrier Proteins - genetics | Phenotype | Animals | Chemical and Drug Induced Liver Injury - metabolism | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Proto-Oncogene Proteins c-myc - genetics | Cell Transformation, Neoplastic - pathology | Carcinoma, Hepatocellular - metabolism | Liver cancer | RNA | Actin | Analysis | Carbon tetrachloride | Muscle proteins | Gene expression | Protein binding | Index Medicus | Abridged Index Medicus | hepatic carcinogenesis | RNA interference | tumorigenesis | cell cycle
Journal Article