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JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2017, Volume 69, Issue 1, pp. 114 - 115
Journal Article
American Journal of Medicine, The, ISSN 0002-9343, 2016
Abstract Background Risk stratification of patients with cardiovascular disease remains challenging despite consideration of risk scores. Methods We aimed to... 
Internal Medicine
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2011, Volume 58, Issue 19, pp. 1955 - 1957
Journal Article
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2008, Volume 51, Issue 20, pp. 1925 - 1934
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2010, Volume 55, Issue 22, pp. 2427 - 2434
Objectives The aim of this study was to evaluate the relative impact of demographic and clinical variables versus the cytochrome P450 2C19 ( CYP2C19 )... 
Cardiovascular | Internal Medicine | polymorphism | predictor | antiplatelet therapy | CYP2C19 | platelet function | RESPONSIVENESS | CARDIAC & CARDIOVASCULAR SYSTEMS | THROMBOSIS | REACTIVITY | DETERMINANT | ANTIPLATELET | THERAPY | INHIBITION | TYPE-2 DIABETES-MELLITUS | INTERVENTION | AGGREGATION | Multivariate Analysis | Predictive Value of Tests | Confidence Intervals | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Aryl Hydrocarbon Hydroxylases - genetics | Male | Dose-Response Relationship, Drug | Prosthesis Failure | Angioplasty, Balloon, Coronary - mortality | Platelet Aggregation Inhibitors - administration & dosage | Ticlopidine - administration & dosage | Adult | Female | Platelet Aggregation - drug effects | Odds Ratio | Platelet Aggregation - genetics | Stents | Drug-Eluting Stents | Coronary Stenosis - therapy | Drug Administration Schedule | Risk Assessment | Angioplasty, Balloon, Coronary - methods | Probability | Coronary Stenosis - drug therapy | Logistic Models | Polymorphism, Genetic - drug effects | Ticlopidine - analogs & derivatives | Coronary Stenosis - genetics | Cytochrome P-450 CYP2C19 | Survival Analysis | Aged | Coronary Stenosis - mortality | Elective Surgical Procedures | Medical colleges | Genetic aspects | Stent (Surgery) | Cytochrome P-450 | Hypertension | Plasma | Aspirin | Heart attacks | Statistical methods | Thrombosis | Polymerase chain reaction | Confidence intervals | Variables | Body mass index | Blood platelets | Intubation | Clinical medicine | Diabetes | Drug therapy | Drug dosages | Deoxyribonucleic acid--DNA | Polymorphism
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 68, Issue 3, pp. 286 - 293
Journal Article
American Journal of Medicine, The, ISSN 0002-9343, 2012, Volume 125, Issue 5, pp. 491 - 498.e1
Journal Article
American Heart Journal, ISSN 0002-8703, 2011, Volume 162, Issue 3, pp. 518 - 526.e5
Background Pharmacodynamic studies reported an amplified on-clopidogrel platelet inhibition in smokers potentially caused by an increased metabolic drug... 
Cardiovascular | PERCUTANEOUS CORONARY INTERVENTION | CIGARETTE-SMOKING | CARDIAC & CARDIOVASCULAR SYSTEMS | INHIBITION | PLATELET-AGGREGATION | STENT THROMBOSIS | OF-FUNCTION POLYMORPHISM | REACTIVITY | EXTRINSIC FACTORS | ASSOCIATION | ACTIVE METABOLITE | Piperazines - administration & dosage | Smoking - adverse effects | Prasugrel Hydrochloride | Purinergic P2Y Receptor Antagonists - administration & dosage | Follow-Up Studies | Humans | Middle Aged | Male | Thiophenes - administration & dosage | Blood Platelets - physiology | Coronary Artery Disease - blood | Cytochrome P-450 CYP1A2 - blood | Dose-Response Relationship, Drug | Time Factors | Platelet Aggregation Inhibitors - administration & dosage | Ticlopidine - administration & dosage | Female | Platelet Aggregation Inhibitors - pharmacokinetics | Ticlopidine - pharmacokinetics | Piperazines - pharmacokinetics | Coronary Artery Disease - etiology | Smoking - blood | Risk Factors | Purinergic P2Y Receptor Antagonists - pharmacokinetics | Platelet Aggregation - physiology | Treatment Outcome | Coronary Artery Disease - drug therapy | Ticlopidine - analogs & derivatives | Cross-Over Studies | Thiophenes - pharmacokinetics | Aged | Hypertension | Enzymes | Heart attacks | Mortality | Statistical methods | Nitrates | Cigarettes | Studies | Variables | Body mass index | Blood platelets | Diabetes | Drug therapy | Acute coronary syndromes | Smoking | Logistics
Journal Article
JACC: Cardiovascular Interventions, ISSN 1936-8798, 2017, Volume 10, Issue 2, pp. 121 - 129
Abstract Objectives This randomized trial tested whether early loading with prasugrel can provide sufficient platelet inhibition even when given at the start... 
Cardiovascular | clopidogrel | percutaneous coronary intervention | prasugrel | cangrelor | ticagrelor | platelet reactivity
Journal Article
American Journal of Medicine, The, ISSN 0002-9343, 2011, Volume 124, Issue 8, pp. 731 - 739
Journal Article
JACC: Cardiovascular Interventions, ISSN 1936-8798, 2016, Volume 9, Issue 3, pp. 219 - 227
Abstract Objectives This randomized trial investigated to what extent loading with prasugrel can provide a more rapid peri-interventional antiplatelet effect... 
Cardiovascular | clopidogrel | percutaneous coronary intervention | prasugrel | platelet reactivity | nonresponder
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2014, Volume 64, Issue 4, pp. 361 - 368
Abstract Background The degree of antiplatelet response to clopidogrel has been associated with clinical outcomes. Studies have investigated whether adjustment... 
Cardiovascular | Internal Medicine | clopidogrel | platelet reactivity | variability | nonresponder | Sects | Medical colleges | Studies | Confidence intervals | Heart attacks | Compliance | Blood platelets | Cardiovascular disease | Drug therapy | Acute coronary syndromes | Thrombosis
Journal Article
American Journal of Medicine, The, ISSN 0002-9343, 2008, Volume 121, Issue 5, pp. 399 - 405
Abstract Background The use of cardiac troponin allows the identification of additional patients developing myocardial necrosis during an acute coronary... 
Internal Medicine | Myocardial infarction | Coronary angiography | Prognosis | Coronary disease | Unstable angina | Guidelines | MANAGEMENT | CHEST-PAIN | myocardial infarction | AMERICAN-COLLEGE | ACUTE CORONARY SYNDROMES | prognosis | EUROPEAN-SOCIETY | coronary disease | MEDICINE, GENERAL & INTERNAL</