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Circulation Research, ISSN 0009-7330, 03/2015, Volume 116, Issue 7, pp. 1109 - 1111
The capacity of the adult mammalian heart to repair itself after injury is limited. In contrast, lower vertebrates such as Zebrafish can completely regenerate... 
THERAPEUTICS | CARDIAC & CARDIOVASCULAR SYSTEMS | HEART REGENERATION | MYOCYTES | MOUSE HEART | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | PROLIFERATION | CARDIOMYOCYTES | HEMATOLOGY | FIBROBLASTS | Mammals - genetics | Animals | Gene Expression Regulation, Developmental | Regeneration - genetics | Heart - physiology | Humans | MicroRNAs - genetics | Index Medicus
Journal Article
Hypertension, ISSN 0194-911X, 09/2018, Volume 72, Issue Suppl_1
Journal Article
Journal Article
STEM CELLS, ISSN 1066-5099, 08/2018, Volume 36, Issue 8, pp. 1198 - 1209
Journal Article
Stem cells (Dayton, Ohio), ISSN 1066-5099, 8/2018, Volume 36, Issue 8, pp. 1198 - 1209
The process by which committed precursors mature into cardiomyocytes is poorly understood. We found that TLR3 inhibition blocked cardiomyocyte maturation;... 
microRNAs | innate immunity | NFκB | cardiomyocyte maturation | cardiomyocyte development | cardiac reprogramming | TLR3
Journal Article
Circulation Research, ISSN 0009-7330, 04/2017, Volume 120, Issue 9, pp. 1403 - 1413
RATIONALE:Direct reprogramming of cardiac fibroblasts to cardiomyocytes has recently emerged as a novel and promising approach to regenerate the injured... 
Cellular reprogramming | Regeneration | Chromatin | Epigenomics | Cardiac myocytes | MicroRNAs | microRNAs | TRANSCRIPTION FACTORS | MOUSE FIBROBLASTS | JMJD3 | DEFINED FACTORS | CARDIAC & CARDIOVASCULAR SYSTEMS | CARDIOMYOCYTE-LIKE CELLS | DEVELOPMENTAL REGULATORS | DNA METHYLATION | regeneration | cellular reprogramming | epigenomics | chromatin | POLYCOMB | PLURIPOTENT STEM-CELLS | cardiac myocytes | SMALL-MOLECULE COMPOUNDS | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | Polycomb Repressive Complex 2 - genetics | Humans | MicroRNAs - metabolism | Histone Demethylases - genetics | Transfection | Cellular Reprogramming Techniques | RNA Interference | Jumonji Domain-Containing Histone Demethylases - antagonists & inhibitors | HEK293 Cells | Epigenesis, Genetic - drug effects | Fibroblasts - metabolism | Animals, Newborn | Signal Transduction | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Gene Expression Regulation | Jumonji Domain-Containing Histone Demethylases - genetics | Cellular Reprogramming - drug effects | Histone Demethylases - metabolism | Animals | Histones - genetics | Myocytes, Cardiac - drug effects | Fibroblasts - drug effects | Myocytes, Cardiac - metabolism | MicroRNAs - genetics | Histones - metabolism | Methylation | Polycomb Repressive Complex 2 - metabolism | DNA Methylation - drug effects | Jumonji Domain-Containing Histone Demethylases - metabolism | Heart | Transcription factors | Immunoprecipitation | MiRNA | Cardiomyocytes | siRNA | Gene expression | Polymerase chain reaction | Gene silencing | Polycomb group proteins | Demethylation | Cell fate | Fibroblasts | Epigenetics | Myocardium | Heart diseases | Index Medicus | Mechanisms | Gene Expression and Regulation
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 10/2018, Volume 123, p. 64
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.yjmcc.2018.08.024... 
Proteins | RNA | Analysis | Stem cells | Cardiology | Gene expression
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 12/2008, Volume 28, Issue 12, pp. 2275 - 2281
Journal Article
Journal Article
Cellular Signalling, ISSN 0898-6568, 06/2018, Volume 46, pp. 113 - 119
The development of biased agonist drugs is widely recognized to be important for the treatment of many diseases, including cardiovascular disease. While GPCR... 
HASF | Insulin-like growth factor (IGF) | Extracellular-signal-regulated kinase (ERK) | Biased agonism | LL37 | IGF1R | PATHWAYS | CELLS | APOPTOSIS | INSULIN-LIKE-GROWTH-FACTOR-1 | AGONISM | ANTIMICROBIAL PEPTIDE LL-37 | CELL BIOLOGY | PARACRINE MECHANISMS | PROTEIN-COUPLED RECEPTOR | BIOLOGY | C3ORF58 | Stem cell research | Protein biosynthesis | Atherosclerosis | Stem cells
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2016, Volume 6, Issue 1, pp. 38815 - 38815
We have recently shown that a combination of microRNAs, miR combo, can directly reprogram cardiac fibroblasts into functional cardiomyocytes in vitro and in... 
CARDIAC FIBROBLASTS | HEART REPAIR | HYDROGELS | MYOCARDIAL-INFARCTION | FUNCTIONAL MATURATION | MATRIX-METALLOPROTEINASE | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | IN-VIVO | OSTEOGENIC DIFFERENTIATION | CULTURE | Myocardial infarction | Heart | Neonates | Cell culture | Tissue engineering | MicroRNAs | MiRNA | Fibroblasts | Cardiomyocytes | Heart diseases | Index Medicus
Journal Article
Scientific Reports, ISSN 2045-2322, 03/2016, Volume 6, Issue 1, pp. 23017 - 23017
We have recently shown that a combination of microRNAs, miR combo, can directly reprogram cardiac fibroblasts into functional cardiomyocytes in vitro and in... 
CARDIAC FIBROBLASTS | SELENOPROTEIN W | MYOCYTES | MULTIDISCIPLINARY SCIENCES | SKELETAL-MUSCLE DIFFERENTIATION | Gene Expression - drug effects | Selenium - pharmacology | Transferrins - pharmacology | SOXB1 Transcription Factors - metabolism | Octamer Transcription Factor-3 - genetics | Cell Differentiation - genetics | RNA Interference | SOXB1 Transcription Factors - genetics | Kruppel-Like Transcription Factors - metabolism | Culture Media - chemistry | Cellular Reprogramming - genetics | Fibroblasts - metabolism | Animals, Newborn | Nanog Homeobox Protein - genetics | Insulin - pharmacology | Myocytes, Cardiac - cytology | Mice, Inbred C57BL | Antioxidants - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Cellular Reprogramming - drug effects | Animals | Myocytes, Cardiac - drug effects | Cell Differentiation - drug effects | Fibroblasts - drug effects | Octamer Transcription Factor-3 - metabolism | Culture Media - pharmacology | Myocytes, Cardiac - metabolism | Fibroblasts - cytology | MicroRNAs - genetics | Kruppel-Like Transcription Factors - genetics | Nanog Homeobox Protein - metabolism | Heart | Neonates | Transferrin | Media (culture) | Oct-4 protein | MiRNA | Media | Cardiomyocytes | siRNA | Gene expression | Insulin | KLF4 protein | Fibroblasts | Selenium | Heart diseases | Pluripotency | Index Medicus
Journal Article
Biochemical Journal, ISSN 0264-6021, 03/2017, Volume 474, Issue 5, pp. 771 - 780
We have recently shown that hypoxia and Akt-induced stem cell factor (HASF) protects the heart from ischemia-induced damage and promotes cardiomyocyte... 
HEART | MORTALITY | HYPERTROPHY | APOPTOSIS | PROTEIN | PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | FAILURE | MESENCHYMAL STEM-CELLS | ELDERLY POPULATION | TRANSGENIC MICE | RNA, Small Interfering - genetics | Receptor, IGF Type 1 - metabolism | Heart Ventricles - cytology | Phosphorylation | Receptor, IGF Type 1 - antagonists & inhibitors | Humans | Adaptor Proteins, Vesicular Transport - genetics | Adaptor Proteins, Vesicular Transport - metabolism | Receptor, IGF Type 2 - metabolism | Receptor, IGF Type 2 - genetics | Receptor, Insulin - genetics | Mitogen-Activated Protein Kinase 1 - genetics | HEK293 Cells | Membrane Proteins - metabolism | Binding Sites | Animals, Newborn | Mitogen-Activated Protein Kinase 3 - genetics | Myocytes, Cardiac - cytology | Signal Transduction | Membrane Proteins - genetics | Adaptor Proteins, Vesicular Transport - antagonists & inhibitors | Gene Expression Regulation | Rats | Pyrimidines - pharmacology | Rats, Sprague-Dawley | Receptor, IGF Type 1 - genetics | Receptor, IGF Type 2 - antagonists & inhibitors | Two-Hybrid System Techniques | Pyrroles - pharmacology | Animals | Myocytes, Cardiac - drug effects | Membrane Proteins - antagonists & inhibitors | Mitogen-Activated Protein Kinase 3 - metabolism | Myocytes, Cardiac - metabolism | Protein Binding | Ligands | Receptor, Insulin - metabolism | Cell Proliferation - drug effects | Heart Ventricles - metabolism | Mice | Primary Cell Culture | Heart Ventricles - drug effects | Mitogen-Activated Protein Kinase 1 - metabolism | RNA, Small Interfering - metabolism | Index Medicus
Journal Article
Circulation Research, ISSN 0009-7330, 12/2014, Volume 115, Issue 12, pp. 1007 - 1016
Journal Article
Journal Article
Journal Article