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The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 11/2018, Volume 142, Issue 5, pp. 1589 - 1604.e11
Journal Article
Journal Article
Integrated Environmental Assessment and Management, ISSN 1551-3777, 05/2019, Volume 15, Issue 3, pp. 312 - 319
Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 12/2014, Volume 88, pp. 89 - 100
Computationally supported development of small molecule inhibitors has successfully been applied to protein tyrosine phosphatases in the past, revealing a... 
2-Cyano-2-ene-esters | Phosphatases of regenerating liver | Enzyme inhibitors | Thienopyridone | Virtual screening methods | Dual specificity phosphatases | CHEMISTRY, MEDICINAL | ULTRAFAST SHAPE-RECOGNITION | METASTASIS | PRL-3 PHOSPHATASE | IDENTIFICATION | DISCOVERY | Cell Survival - drug effects | Small Molecule Libraries - pharmacology | Liver Regeneration | Liver - enzymology | Humans | Cells, Cultured | Enzyme Inhibitors - pharmacology | Neoplasms - enzymology | Structure-Activity Relationship | Dose-Response Relationship, Drug | Cell Movement - drug effects | Small Molecule Libraries - chemistry | High-Throughput Screening Assays | Enzyme Inhibitors - chemistry | HEK293 Cells | Cell Proliferation - drug effects | Molecular Docking Simulation | Molecular Structure | Neoplasms - pathology | Phosphoric Monoester Hydrolases - metabolism | Phosphoric Monoester Hydrolases - antagonists & inhibitors | Liver cancer | Phosphatases | Analysis | Liver | Genomics | Nitriles | Methods | PRL, phosphatases of regenerating liver | DIFMUP, 6,8-difluoro-4-methylumbelliferyl phosphate | UPLC-MS, ultra performance liquid chromatography–mass spectrometry | PTP1B, protein tyrosine phosphatase 1B | UFSRAT, ultrafast shape recognition with atom types | VHR, vaccinia H1-related phosphatase | SAR, structure–activity relationship | VS, virtual screening | DSP, dual specificity phosphatase | ROCS, rapid overlay of chemical structures | TCPTP, T-cell protein tyrosine phosphatase | Original | MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide | PTP, protein tyrosine phosphatase | USR, ultrafast shape recognition
Journal Article
Journal Article
by Farmer, Jocelyn R and Foldvari, Zsofia and Ujhazi, Boglarka and De Ravin, Suk See and Chen, Karin and Bleesing, Jack J.H and Schuetz, Catharina and Al-Herz, Waleed and Abraham, Roshini S and Joshi, Avni Y and Costa-Carvalho, Beatriz T and Buchbinder, David and Booth, Claire and Reiff, Andreas and Ferguson, Polly J and Aghamohammadi, Asghar and Abolhassani, Hassan and Puck, Jennifer M and Adeli, Mehdi and Cancrini, Caterina and Palma, Paolo and Bertaina, Alice and Locatelli, Franco and Di Matteo, Gigliola and Geha, Raif S and Kanariou, Maria G and Lycopoulou, Lilia and Tzanoudaki, Marianna and Sleasman, John W and Parikh, Suhag and Pinero, Gloria and Fischer, Bernard M and Dbaibo, Ghassan and Unal, Ekrem and Patiroglu, Turkan and Karakukcu, Musa and Al-Saad, Khulood Khalifa and Dilley, Meredith A and Pai, Sung-Yun and Dutmer, Cullen M and Gelfand, Erwin W and Geier, Christoph B and Eibl, Martha M and Wolf, Hermann M and Henderson, Lauren A and Hazen, Melissa M and Bonfim, Carmem and Wolska-Kuśnierz, Beata and Butte, Manish J and Hernandez, Joseph D and Nicholas, Sarah K and Stepensky, Polina and Chandrakasan, Shanmuganathan and Miano, Maurizio and Westermann-Clark, Emma and Goda, Vera and Kriván, Gergely and Holland, Steven M and Fadugba, Olajumoke and Henrickson, Sarah E and Ozen, Ahmet and Karakoc-Aydiner, Elif and Baris, Safa and Kiykim, Ayca and Bredius, Robbert and Hoeger, Birgit and Boztug, Kaan and Pashchenko, Olga and Neven, Benedicte and Moshous, Despina and Villartay, Jean-Pierre de and Bousfiha, Ahmed Aziz and Hill, Harry R and Notarangelo, Luigi D and Walter, Jolan E
The Journal of Allergy and Clinical Immunology: In Practice, ISSN 2213-2198, 07/2019, Volume 7, Issue 6, pp. 1970 - 1985.e4
Journal Article
Journal Article
Toxicological Sciences, ISSN 1096-6080, 01/2011, Volume 119, Issue 1, pp. 104 - 115
To identify molecular effects of the antineoplastic agent protein kinase C inhibitor 412 (PKC412) (midostaurin), we applied gene expression profiling in... 
Journal Article
Journal Article