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analysis (8) 8
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1. Full Text SR-BI as target in atherosclerosis and cardiovascular disease - A comprehensive appraisal of the cellular functions of SR-BI in physiology and disease
by Hoekstra, Menno
Atherosclerosis, ISSN 0021-9150, 2017, Volume 258, pp. 153 - 161
Cardiovascular | Cardiovascular disease | SR-BI | Knockout mice | High-density lipoprotein | Cell types | Atherosclerosis | Cardiac & Cardiovascular Systems | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Atherosclerosis - pathology | CD36 Antigens - therapeutic use | Atherosclerosis - drug therapy | CD36 Antigens - agonists | CD36 Antigens - genetics | Signal Transduction | Atherosclerosis - genetics | Humans | Mice, Transgenic | Arteries - drug effects | Arteries - pathology | Molecular Targeted Therapy | Plaque, Atherosclerotic | Atherosclerosis - metabolism | Arteries - metabolism | Cardiovascular Agents - therapeutic use | Animals | CD36 Antigens - metabolism | Drug Design | Disease Models, Animal | Physiological aspects | Disease susceptibility | Blood lipids | Cardiovascular diseases | Liver | Medical research | Medicine, Experimental | Esters | Index Medicus
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2. Full Text Genetic Variant of the Scavenger Receptor BI in Humans
by Vergeer, Menno and Korporaal, Suzanne J.A and Franssen, Remco and Meurs, Illiana and Out, Ruud and Hovingh, G. Kees and Hoekstra, Menno and Sierts, Jeroen A and Dallinga-Thie, Geesje M and Motazacker, Mohammad Mahdi and Holleboom, Adriaan G and Van Berkel, Theo J.C and Kastelein, John J.P and Van Eck, Miranda and Kuivenhoven, Jan Albert
The New England journal of medicine, ISSN 0028-4793, 01/2011, Volume 364, Issue 2, pp. 136 - 145
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Adrenal Insufficiency - genetics | Atherosclerosis - genetics | Cholesterol - blood | Humans | Middle Aged | Hydrocortisone - metabolism | Male | Mutation, Missense | Young Adult | DNA Mutational Analysis | Aged, 80 and over | Adult | Carotid Arteries - anatomy & histology | Female | Scavenger Receptors, Class B - genetics | Cholesterol - metabolism | Mice, Knockout | Platelet Activation - genetics | Macrophages - metabolism | Animals | Pedigree | Adolescent | Triglycerides - blood | Cholesterol, HDL - blood | Adrenal Glands - physiology | Heterozygote | Aged | Mice | Homeostasis - genetics | Cholesterol, HDL | Atherosclerosis | Physiological aspects | Genetic aspects | Health aspects | Liver cells | Risk factors | Proteins | Lipoproteins | Adenoviruses | Lipids | Mutation | Experiments | Cholesterol | Index Medicus | Abridged Index Medicus
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3. Full Text Probucol-induced hypocholesterolemia is not associated with exacerbated foam cell formation in ABCG1 knockout mice
by Hoekstra, Menno and Van Eck, Miranda
Atherosclerosis, ISSN 0021-9150, 03/2020, Volume 296, pp. 91 - 92
Probucol | Mouse model | ABC transporter | Macrophage foam cell | Cholesterol efflux | Cardiac & Cardiovascular Systems | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | ATP Binding Cassette Transporter, Subfamily G, Member 1 | Animals | Foam Cells | Atherosclerosis | Apolipoproteins E | Mice | Mice, Knockout, ApoE | Bone Marrow | Mice, Knockout | Index Medicus
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4. Full Text Rediscovering scavenger receptor type BI: Surprising new roles for the HDL receptor
by Hoekstra, Menno and Sorci-Thomas, Mary
Current opinion in lipidology, ISSN 0957-9672, 06/2017, Volume 28, Issue 3, pp. 255 - 260
cardiovascular disease | HDL | cancer | scavenger receptor type BI | inflammation | Biochemistry & Molecular Biology | Endocrinology & Metabolism | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Neoplasms - metabolism | Inflammation - metabolism | Animals | CD36 Antigens - metabolism | Humans | Biomarkers, Tumor - metabolism | Molecular Targeted Therapy | Neoplasms - drug therapy | Index Medicus
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5. Full Text Glucocorticoids are active players and therapeutic targets in atherosclerotic cardiovascular disease
by van der Sluis, Ronald J and Hoekstra, Menno
Molecular and cellular endocrinology, ISSN 0303-7207, 03/2020, Volume 504, pp. 110728 - 110728
Metabolic disease | Cardiovascular disease | Glucocorticoid | Cholesterol | Atherosclerosis | Scavenger receptor BI | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Medical research | Corticosteroids | Analysis | Medicine, Experimental | Development and progression | Cardiovascular diseases | Health aspects | Index Medicus
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6. Full Text Identification of scavenger receptor BI as a potential screening candidate for congenital primary adrenal insufficiency in humans
by Hoekstra, Menno
American journal of physiology: endocrinology and metabolism, ISSN 0193-1849, 06/2020, Volume 319, Issue 1, pp. E102 - E104
Endocrinology & Metabolism | Physiology | Life Sciences & Biomedicine | Science & Technology | Index Medicus
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7. Full Text HDL is redundant for adrenal steroidogenesis in LDLR knockout mice with a human-like lipoprotein profile
by Hoekstra, Menno and Van Eck, Miranda
Journal of lipid research, ISSN 0022-2275, 04/2016, Volume 57, Issue 4, pp. 631 - 637
Low density lipoprotein receptor | Corticosterone | High density lipoprotein | Gene expression | Low density lipoprotein | Cholesterol | Steroid hormones | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Receptors, LDL - genetics | Animals | Humans | Receptors, LDL - deficiency | Cholesterol, HDL - blood | Male | Mice | Corticosterone - blood | Mice, Knockout | Index Medicus | low density lipoprotein | s | cholesterol | low density lipoprotein receptor | steroid hormones | high density lipoprotein | corticosterone | gene expression
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8. Full Text Inhibition of protein arginine methyltransferase 3 activity selectively impairs liver X receptor‐driven transcription of hepatic lipogenic genes in vivo
by Nahon, Joya E and Groeneveldt, Christianne and Geerling, Janine J and Eck, Miranda and Hoekstra, Menno
British journal of pharmacology, ISSN 0007-1188, 08/2018, Volume 175, Issue 15, pp. 3175 - 3183
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Transcription, Genetic - drug effects | Cholesterol - blood | Liver - metabolism | Mice, Inbred C57BL | Hydrocarbons, Fluorinated - pharmacology | Protein-Arginine N-Methyltransferases - antagonists & inhibitors | Male | Sulfonamides - pharmacology | Macrophages - metabolism | Animals | Isoquinolines - pharmacology | ATP Binding Cassette Transporter, Subfamily G, Member 1 - genetics | Lipogenesis - genetics | Liver - drug effects | Lipogenesis - drug effects | Liver X Receptors - agonists | Triglycerides - blood | Palm Oil - pharmacology | Liver X Receptors - genetics | ATP Binding Cassette Transporter 1 - genetics | Synthesis | Arginine | Genes | Transferases | Liver | Genetic research | Genetic aspects | Mice | Triglycerides | Genetic transcription | Fatty acids | Homeostasis | Macrophages | Desaturase | ABCA1 protein | Proteins | Allosteric properties | Fatty liver | Pathways | Rodents | Transcription activation | Coenzyme A | Inhibition | Lipogenesis | Efflux | Vegetable oils | Liver X receptors | Protein arginine methyltransferase | Gene expression | Fatty-acid synthase | Cholesterol | Steatosis | Palm oil | ATP-binding protein | Transporter | Peritoneum | Index Medicus | Research Papers | Research Paper
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9. Full Text Total body proteoglycan 4 (Prg4) deficiency increases atherosclerosis susceptibility in apolipoprotein E knockout and low-density lipoprotein receptor knockout mice
by Nahon, Joya E and Hoekstra, Menno and Van Eck, Miranda
Atherosclerosis, ISSN 0021-9150, 11/2018, Volume 278, pp. 315 - 316
Hyperlipidemic models | Proteoglycan 4 | Total body knockout mice | Atherosclerosis | Cardiac & Cardiovascular Systems | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Index Medicus
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10. Full Text Functional outcome of intra-articular tibial plateau fractures: the impact of posterior column fractures
by van den Berg, Juriaan and Reul, Maike and Nunes Cardozo, Menno and Starovoyt, Anastasiya and Geusens, Eric and Nijs, Stefaan and Hoekstra, Harm
International orthopaedics, ISSN 0341-2695, 9/2017, Volume 41, Issue 9, pp. 1865 - 1873
Tibial plateau fractures | Posterior column | Medicine & Public Health | Orthopedics | Three-column classification | Functional outcome | Life Sciences & Biomedicine | Science & Technology | Tibial Fractures - epidemiology | Fracture Fixation - methods | Knee Injuries - physiopathology | Humans | Knee Joint - physiopathology | Middle Aged | Fracture Fixation, Internal - methods | Male | Tibia - injuries | Incidence | Knee Injuries - therapy | Adult | Female | Knee Injuries - diagnosis | Retrospective Studies | Tibial Fractures - therapy | Tibial Fractures - diagnosis | Intra-Articular Fractures - epidemiology | Treatment Outcome | Tibia - surgery | Intra-Articular Fractures - diagnosis | Intra-Articular Fractures - therapy | Aged | Osteoarthritis, Knee - physiopathology | Cohort Studies | Medicine, Experimental | Internal fixation in fractures | Medical research | Fractures | Health aspects | Osteoarthritis | Index Medicus
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11. Full Text Adrenocortical LDL receptor function negatively influences glucocorticoid output
by van der Sluis, Ronald J and Van Eck, Miranda and Hoekstra, Menno
Journal of endocrinology, ISSN 0022-0795, 09/2015, Volume 226, Issue 3, pp. 145 - 154
Corticosterone | LDL | Receptor | Mice | Steroidogenesis | Transplantation | Lipoprotein | Adrenal | Cholesterol | Life Sciences & Biomedicine | Endo