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1. Full Text Expression profiling - Best practices for data generation and interpretation in clinical trials: The Tumor Analysis Best Practices Working Group
by Hoffman, Eric P
Nature Reviews Genetics, ISSN 1471-0056, 03/2004, Volume 5, Issue 3, pp. 229 - 237
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2. Full Text Asymmetric independence modeling identifies novel gene-environment interactions
by Yu, Guoqiang and Miller, David J and Wu, Chiung-Ting and Hoffman, Eric P and Liu, Chunyu and Herrington, David M and Wang, Yue
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 2455 - 9
Most genetic or environmental factors work together in determining complex disease risk. Detecting gene-environment interactions may allow us to elucidate... 
TOBACCO SMOKING | RISK | ESOPHAGEAL CANCER | ALCOHOL INTAKE | EPISTASIS | MULTIDISCIPLINARY SCIENCES | Environmental factors | Mathematical models | Molecular modelling
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3. Full Text Developmental Pharmacodynamics and Modeling in Pediatric Drug Development
by Conklin, Laurie S and Hoffman, Eric P and den Anker, John
The Journal of Clinical Pharmacology, ISSN 0091-2700, 09/2019, Volume 59, Issue S1, pp. S87 - S94
Challenges in pediatric drug development include small patient numbers, limited outcomes research, ethical barriers, and sparse biosamples. Increasingly,... 
drug development | extrapolation | modeling | pharmacodynamics | pediatrics | Subpopulations | Pediatrics | Pharmacodynamics | Data points | Pharmacology | Drug development | Patients | Extrapolation | Developmental stages | Biomarkers | Bioindicators | Modelling | Adults | Index Medicus
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4. Genetic and molecular aspects of sport performance
by Bouchard, Claude and Hoffman, Eric P and IOC Medical Commission
2011, Encyclopaedia of sports medicine, ISBN 144433445X, Volume 18
Genetic Phenomena | Athletic ability | Exercise | Sports Medicine | Athletic Performance | methods | Physiological aspects | physiology | Human genetics | Sports
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5. Full Text Expression Profiling in the Muscular Dystrophies: Identification of Novel Aspects of Molecular Pathophysiology
by Yi-Wen Chen and Po Zhao and Rehannah Borup and Eric P. Hoffman
The Journal of Cell Biology, ISSN 0021-9525, 12/2000, Volume 151, Issue 6, pp. 1321 - 1336
We used expression profiling to define the pathophysiological cascades involved in the progression of two muscular dystrophies with known primary biochemical... 
Up regulation | Dendritic cells | RNA | Duchenne muscular dystrophy | Genes | Muscles | Actins | Muscular dystrophies | Biopsies | Gene expression regulation | Expression profiling | α-sarcoglycan | Microarray | Dystrophin | Muscular dystrophy | alpha-sarcoglycan | MDX MOUSE | PROTEIN | DENDRITIC CELLS | expression profiling | MAST-CELLS | GAMMA-SARCOGLYCAN | dystrophin | CELL BIOLOGY | SKELETAL-MUSCLE | OLIGONUCLEOTIDE ARRAYS | MESSENGER-RNAS | muscular dystrophy | microarray | GENE | EXTRACELLULAR-MATRIX | Chondroitin Sulfate Proteoglycans - genetics | Oligonucleotide Array Sequence Analysis | Thrombospondins - genetics | Humans | Myosin Heavy Chains - genetics | Male | Muscular Dystrophies - genetics | Muscular Dystrophy, Duchenne - etiology | Actins - genetics | Cytoskeletal Proteins - deficiency | HLA-DR Antigens - genetics | Osteonectin - genetics | Actins - analysis | Dystrophin - deficiency | Muscle, Skeletal - chemistry | Female | Muscular Dystrophies - etiology | Child | Myosin Heavy Chains - analysis | Chondroitin Sulfate Proteoglycans - analysis | Thrombospondins - analysis | Lectins, C-Type | Gene Expression Profiling - methods | Factor VIIIa - genetics | Versicans | Biopsy | Osteonectin - analysis | Sarcoglycans | Factor VIIIa - analysis | HLA-DR Antigens - analysis | Muscular Dystrophy, Duchenne - genetics | Membrane Glycoproteins - deficiency | Physiological aspects | Cell research | Research | Gene expression | Analysis | Pathology | Genetics | Cellular biology | Molecular biology | histocompatibility antigen HLA | coagulation factor XIIIa | a-sarcoglycan | Index Medicus | Original
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6. Full Text Gene Expression Changes Associated with Insulin Sensitivity Variation Following Exercise Training
: 729 Board #125 May 27, 2
by Barberio, Matthew D and Huffman, Kim M and Hoffman, Eric P and Kraus, William E and Hubal, Monica J
Medicine & Science in Sports & Exercise, ISSN 0195-9131, 05/2015, Volume 47, pp. 190 - 191
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7. The letter forms and type designs of Eric Gill
by Gill, Eric, 1882-1940 and Harling, Robert
1976, ISBN 0903696045, 64 p., [4] p. of plates (4 fold.)
Lettering | Type and type-founding | Gill, Eric, 1882-1940
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8. Full Text A calm before the exome storm Coming together of dSMA and CMT2
by Hoffman, Eric P and Talbot, Kevin
Neurology, ISSN 0028-3878, 05/2012, Volume 78, Issue 22, pp. 1706 - 1707
GENE | MUTATION | DISEASE | DOMINANT | MICE | SENSORY NEUROPATHY | CLINICAL NEUROLOGY | Spinal Muscular Atrophies of Childhood - genetics | Genes, Dominant | Humans | Cytoplasmic Dyneins - genetics | Lower Extremity | Chromosomes, Human, Pair 14 | Female | Male | Polymorphism, Single Nucleotide | Mutation, Missense | Index Medicus | Abridged Index Medicus
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9. Full Text Genetic modifiers of ambulation in the cooperative international Neuromuscular research group Duchenne natural history study
: Ambulation in CINRG-DNHS
by Bello, Luca and Kesari, Akanchha and Gordish-Dressman, Heather and Cnaan, Avital and Morgenroth, Lauren P and Punetha, Jaya and Duong, Tina and Henricson, Erik K and Pegoraro, Elena and McDonald, Craig M and Hoffman, Eric P and on behalf of the Cooperative International Neuromuscular Research Group Investigators
Annals of Neurology, ISSN 0364-5134, 04/2015, Volume 77, Issue 4, pp. 684 - 696
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10. Full Text The authors reply
by Mefford, Heather C and Batshaw, Mark L and Hoffman, Eric P
New England Journal of Medicine, ISSN 0028-4793, 06/2012, Volume 366, Issue 23, p. 2232
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11. Full Text Neuro-oncology: Understanding the molecular complexity of medulloblastoma
by Packer, Roger J and Hoffman, Eric P
Nature Reviews Neurology, ISSN 1759-4758, 10/2012, Volume 8, Issue 10, pp. 539 - 540
The understanding and treatment of medulloblastoma, the most common childhood malignant brain tumour, is rapidly evolving. Three complementary deep-sequencing... 
ADJUVANT CHEMOTHERAPY | CLINICAL NEUROLOGY | Medical Oncology - methods | Brain Neoplasms - chemistry | Brain Neoplasms - diagnosis | Humans | Molecular Dynamics Simulation - trends | Brain Neoplasms - genetics | Medulloblastoma - diagnosis | Mutation - genetics | Medulloblastoma - chemistry | Medical Oncology - trends | Molecular Dynamics Simulation - standards | Biomarkers, Tumor - metabolism | Biomarkers, Tumor - genetics | Biomarkers, Tumor - chemistry | Medulloblastoma - genetics
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12. Full Text Metataxonomic and Metagenomic Approaches Versus Culture-Based Techniques For Clinical Pathology
by Sarah K Hilton and Eduardo eCastro Nallar and Eduardo eCastro Nallar and Marcos ePérez-Losada and Marcos ePérez-Losada and Marcos ePérez-Losada and Ian eToma and Timothy A McCaffrey and Eric P. Hoffman and Marc O. Siegel and Gary L. Simon and W. Evan Johnson and Keith A Crandall
Frontiers in Microbiology, 04/2016, Volume 7
Diagnoses that are both timely and accurate are critically important for patients with life-threatening or drug resistant infections. Technological... 
Metagenomics | high throughput sequencing | microbiome | Drug Resistance | metataxonomics | Pathogen Detection
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13. Full Text Corrigendum to "VBP15: Preclinical characterization of a novel anti-inflammatory delta 9,11 steroid" [Bioorg. Med. Chem. 21 2241-2249]
by Reeves, Erica K.M and Hoffman, Eric P and Nagaraju, Kanneboyina and Damsker, Jesse M and McCall, John M
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 04/2015, Volume 23, Issue 7, p. 1664
Anti-inflammatory drugs
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14. Full Text Corrigendum to “VBP15: Preclinical characterization of a novel anti-inflammatory delta 9,11 steroid” [Bioorg. Med. Chem. 21 (2013) 2241–2249]
by Reeves, Erica K.M and Hoffman, Eric P and Nagaraju, Kanneboyina and Damsker, Jesse M and McCall, John M
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 04/2015, Volume 23, Issue 7, pp. 1664 - 1664
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15. Full Text Erratum: VBP15: Preclinical characterization of a novel anti-inflammatory delta 9,11 steroid (Bioorganic and Medicinal Chemistry (2013) 21 (2241-2249) DOI: 10.1016/j.bmc.2015.01.034)
by Reeves, Erica K.M and Hoffman, Eric P and Nagaraju, Kanneboyina and Damsker, Jesse M and McCall, John M
Bioorganic and Medicinal Chemistry, ISSN 0968-0896, 04/2015, Volume 23, Issue 7, p. 1664
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16. Full Text In Vivo and in Vitro Characterization of Novel Neuronal Plasticity Factors Identified following Spinal Cord Injury
by Simone Di Giovanni and Andrea De Biase and Alexander Yakovlev and Tom Finn and Jeanette Beers and Eric P. Hoffman and Alan I. Faden
Journal of Biological Chemistry, ISSN 0021-9258, 01/2005, Volume 280, Issue 3, pp. 2084 - 2091
Following spinal cord injury, there are numerous changes in gene expression that appear to contribute to either neurodegeneration or reparative processes. We... 
NEURITE OUTGROWTH | ADHESION MOLECULE | GROWTH-ASSOCIATED PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION | PC12 CELLS | AXONAL GROWTH | CORONIN FAMILY | ACTIN-BINDING PROTEIN | SENSORY NEURONS | TRANSGENIC MICE | Immunohistochemistry | Multigene Family | Spinal Cord Injuries - metabolism | Rats | Male | rab GTP-Binding Proteins - genetics | Gene Expression Profiling | DNA Primers | Rats, Sprague-Dawley | Animals | RNA Interference | Neuronal Plasticity | Base Sequence | Microfilament Proteins - metabolism | Spinal Cord Injuries - physiopathology | Ganglia, Spinal - metabolism | Index Medicus
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17. Full Text In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs
by Tefferi, Ayalew, MD and Kantarjian, Hagop, MD and Rajkumar, S. Vincent, MD and Baker, Lawrence H., DO and Abkowitz, Jan L., MD and Adamson, John W., MD and Advani, Ranjana Hira, MD and Allison, James, MD and Antman, Karen H., MD and Bast, Robert C., MD and Bennett, John M., MD and Benz, Edward J., MD and Berliner, Nancy, MD and Bertino, Joseph, MD and Bhatia, Ravi, MD and Bhatia, Smita, MD and Bhojwani, Deepa, MD and Blanke, Charles D., MD and Bloomfield, Clara D., MD and Bosserman, Linda, MD and Broxmeyer, Hal E., PhD and Byrd, John C., MD and Cabanillas, Fernando, MD and Canellos, George Peter, MD and Chabner, Bruce A., MD and Chanan-Khan, Asher, MD and Cheson, Bruce, MD and Clarkson, Bayard, MD and Cohn, Susan L., MD and Colon-Otero, Gerardo, MD and Cortes, Jorge, MD and Coutre, Steven, MD and Cristofanilli, Massimo, MD and Curran, Walter J., MD and Daley, George Q., MD, PhD and DeAngelo, Daniel J., MD, PhD and Deeg, H. Joachim, MD and Einhorn, Lawrence H., MD and Erba, Harry P., MD, PhD and Esteva, Francisco J., MD, PhD and Estey, Elihu, MD and Fidler, Isaiah J., DVM, PhD and Foran, James, MD and Forman, Stephen, MD and Freireich, Emil, MD and Fuchs, Charles, MD, MPH and George, James N., MD and Gertz, Morie A., MD and Giralt, Sergio, MD and Golomb, Harvey, MD and Greenberg, Peter, MD and Gutterman, Jordan, MD and Handin, Robert I., MD and Hellman, Samuel, MD and Hoff, Paulo Marcelo, MD and Hoffman, Ronald, MD and Hong, Waun Ki, MD and Horowitz, Mary, MD, MS and Hortobagyi, Gabriel N., MD and Hudis, Clifford, MD and Issa, Jean Pierre, MD and Johnson, Bruce Evan, MD and Kantoff, Philip W., MD and Kaushansky, Kenneth, MD and Khayat, David, MD, PhD and Khuri, Fadlo R., MD and Kipps, Thomas J., MD, PhD and Kripke, Margaret, PhD and Kyle, Robert A., MD and Larson, Richard A., MD and Lawrence, Theodore S., MD, PhD and Levine, Ross, MD and Link, Michael P., MD and Lippman, Scott M., MD and Lonial, Sagar, MD and Lyman, Gary H., MD, MPH and Markman, Maurie, MD and Mendelsohn, John, MD and Meropol, Neal J., MD and Messinger, Yoav, MD and Mulvey, Therese M., MD and O’Brien, Susan, MD and Perez-Soler, Roman, MD and Pollock, Raphael, MD, PhD and Prchal, Josef, MD and Press, Oliver, MD, PhD and Radich, Jerald, MD and Rai, Kanti, MD and Rosenberg, Saul A., MD and Rowe, Jacob M., MD and Rugo, Hope, MD and Runowicz, Carolyn D., MD and Sandmaier, Brenda M., MD and Saven, Alan, MD and Schafer, Andrew I., MD and Schiffer, Charles, MD and Sekeres, Mikkael A., MD, MS and Silver, Richard T., MD and Siu, Lillian L., MD and Steensma, David P., MD and ...
Mayo Clinic Proceedings, ISSN 0025-6196, 2015, Volume 90, Issue 8, pp. 996 - 1000
Internal Medicine | MEDICINE, GENERAL & INTERNAL | Drug Costs | United States - epidemiology | Neoplasms - economics | Humans | Patient Participation | Patient Advocacy | Antineoplastic Agents - economics | Neoplasms - epidemiology | Prescription Fees | Neoplasms - drug therapy | Antimitotic agents | Cancer patients | Patient outcomes | Economic aspects | Dosage and administration | Drug therapy | Antineoplastic agents | Index Medicus | Abridged Index Medicus
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18. Full Text Neurodevelopmental Needs in Young Boys with Duchenne Muscular Dystrophy (DMD): Observations from the Cooperative International Neuromuscular Research Group (CINRG) DMD Natural History Study (DNHS)
by Thangarajh, Mathula and Spurney, Christopher F and Gordish-Dressman, Heather and Clemens, Paula R and Hoffman, Eric P and McDonald, Craig M and Henricson, Erik K and Investigators, Cinrg
PLoS currents, ISSN 2157-3999, 10/2018, Volume 10
Duchenne muscular dystrophy (DMD) is the most common X-linked neuromuscular condition manifested by progressive skeletal muscle weakness, cardiopulmonary... 
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19. Full Text Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt
by Fulco, Marcella and Cen, Yana and Zhao, Po and Hoffman, Eric P and McBurney, Michael W and Sauve, Anthony A and Sartorelli, Vittorio
Developmental Cell, ISSN 1534-5807, 2008, Volume 14, Issue 5, pp. 661 - 673
It is intuitive to speculate that nutrient availability may influence differentiation of mammalian cells. Nonetheless, a comprehensive complement of the... 
HUMDISEASE | DEVBIO | LIFE-SPAN EXTENSION | TRANSCRIPTION FACTORS | MUSCLE DIFFERENTIATION | CAENORHABDITIS-ELEGANS | PROTEIN-KINASE | INSULIN-SECRETION | PANCREATIC BETA-CELLS | NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE | DEVELOPMENTAL BIOLOGY | SACCHAROMYCES-CEREVISIAE | CALORIE RESTRICTION | CELL BIOLOGY | Cell Line | Cytokines - metabolism | Gene Expression Regulation | Multienzyme Complexes - metabolism | Myoblasts, Skeletal - enzymology | AMP-Activated Protein Kinases | Myoblasts, Skeletal - cytology | Nicotinamide Phosphoribosyltransferase - genetics | Animals | Nicotinamide Phosphoribosyltransferase - metabolism | Sirtuin 1 | Glucose - metabolism | Food Deprivation | Transcription, Genetic | Cell Differentiation | Mice | Mice, Inbred BALB C | Enzyme Activation | Sirtuins - genetics | Cytokines - genetics | Sirtuins - metabolism | NAD - metabolism | Protein-Serine-Threonine Kinases - metabolism | Dextrose | Glucose | Index Medicus
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20. Full Text Skipping toward Personalized Molecular Medicine
by Hoffman, Eric P
The New England Journal of Medicine, ISSN 0028-4793, 12/2007, Volume 357, Issue 26, pp. 2719 - 2722
“Personalized molecular medicine.” As with other catchy terms for big ideas, such as “reversing global warming” and “renewable energy,” the concept of... 
SYSTEMIC DELIVERY | MEDICINE, GENERAL & INTERNAL | DUCHENNE MUSCULAR-DYSTROPHY | EXPRESSION | Sequence Deletion | Transcription, Genetic - drug effects | Gene Expression | Exons | Muscular Dystrophy, Duchenne - drug therapy | Humans | Dystrophin - biosynthesis | Male | Drug Approval | Dystrophin - genetics | Oligonucleotides, Antisense - therapeutic use | Drug Design | Muscular Dystrophy, Duchenne - genetics | Duchenne muscular dystrophy | Genetic aspects | Research | Nucleic acids | Drug therapy | Health aspects | Mutation (Biology) | Proteins | Mutation | Rodents | Muscular dystrophy | Index Medicus | Abridged Index Medicus
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