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American Journal of Physiology: Cell Physiology, ISSN 0363-6143, 06/2016, Volume 310, Issue 11, pp. C857 - C857
The leucine-rich repeat containing 8A (LRRC8A) protein is an essential component of the volume-sensitive organic anion channel (VSOAC), and using... 
Journal Article
IUBMB Life, ISSN 1521-6543, 04/2014, Volume 66, Issue 4, pp. 257 - 267
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 06/2016, Volume 310, Issue 11, pp. C857 - C873
The leucine-rich repeat containing 8A (LRRC8A) protein is an essential component of the volume-sensitive organic anion channel (VSOAC), and using... 
Taurine | Transcription factors | Multidrug resistance | Organic anion channels | Apoptosis | Platinum drugs | Lung Neoplasms - drug therapy | Proto-Oncogene Proteins c-mdm2 - genetics | Caspase 9 - genetics | Caspase 9 - metabolism | Cation Transport Proteins - antagonists & inhibitors | Adenocarcinoma, Bronchiolo-Alveolar - pathology | Apoptosis - drug effects | Humans | Caspase 3 - metabolism | Gene Expression Regulation, Neoplastic | Ovarian Neoplasms - pathology | Drug Resistance, Neoplasm | Lung Neoplasms - pathology | Tumor Suppressor Protein p53 - genetics | Adenocarcinoma, Bronchiolo-Alveolar - genetics | Ovarian Neoplasms - genetics | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Transfection | Anion Transport Proteins - antagonists & inhibitors | RNA Interference | Time Factors | Cation Transport Proteins - metabolism | Membrane Transport Modulators - pharmacology | Caspase 3 - genetics | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Female | Antineoplastic Agents - pharmacology | Membrane Proteins - metabolism | Ovarian Neoplasms - drug therapy | Proto-Oncogene Proteins c-mdm2 - metabolism | Adenocarcinoma, Bronchiolo-Alveolar - enzymology | Lung Neoplasms - genetics | A549 Cells | Lung Neoplasms - enzymology | Membrane Proteins - genetics | Down-Regulation | Tumor Suppressor Protein p53 - metabolism | Cell Size | Cisplatin - pharmacology | Anion Transport Proteins - metabolism | Ovarian Neoplasms - enzymology | Signal Transduction - drug effects | Adenocarcinoma, Bronchiolo-Alveolar - drug therapy | Call for Papers | multidrug resistance | transcription factors | platinum drugs | organic anion channels | taurine | apoptosis
Journal Article
American Journal of Physiology, ISSN 0363-6143, 09/2010, Volume 299, Issue 3, p. C714
  Channels and transporters of monovalent ions are increasingly suggested as putative anticarcinogenic targets. However, the mechanisms involved in modulation... 
Pathology | Membranes | Sodium | Chlorine | Ions | Potassium | Cells
Journal Article
American Journal of Physiology, ISSN 0363-6143, 10/2010, Volume 299, Issue 4, p. C844
  The swelling-activated ... currents (...) in Ehrlich ascites tumor cells (EATC) has been reported to be through the two-pore domain (...), TWIK-related... 
Enzymes | Phosphorylation | Amino acids | Kinases | Potassium | Cells
Journal Article
American Journal of Physiology, ISSN 0363-6143, 06/2016, Volume 310, Issue 11, p. C857
  The leucine-rich repeat containing 8A (LRRC8A) protein is an essential component of the volume-sensitive organic anion channel (VSOAC), and using... 
Protein expression | TNF inhibitors | Ovarian cancer | Apoptosis
Journal Article
Physiological Reports, 06/2015, Volume 3, Issue 6
The aim of this project was to analyze the regulation of p53 expression in NIH3T3 fibroblasts under the influence of increasing hyperosmotic stress. Expression... 
Ubiquitin | Cell culture | Phosphorylation | MDM2 protein | Immunoglobulins | Osmolarity | p53 Protein | Caspase | MAP kinase | Osmosis | Kinases | Proteasome inhibitors | Osmotic stress | Proteins | Hypertonicity | Cell cycle | Proteasomes | Fibroblasts | Annexin V | Ubiquitin-protein ligase | Apoptosis
Journal Article
American Journal of Physiology (Consolidated), ISSN 0002-9513, 06/2016, Volume 310, Issue 6, p. C857
The leucine-rich repeat containing 8A (LRRC8A) protein is an essential component of the volume-sensitive organic anion channel (VSOAC), and using... 
Carcinoma | Oncology, Experimental | Cancer cells | Physiological aspects | Research | Tumor proteins | Drug resistance | Cisplatin | Cancer
Journal Article
American Journal of Physiology, ISSN 0363-6143, 01/2015, Volume 308, Issue 2, p. C101
  The mechanisms linking cell volume sensing to volume regulation in mammalian cells remain incompletely understood. Here, we test the hypothesis that... 
Phosphorylation | Light | Osmosis | Shrinkage | Kinases | Cells
Journal Article
FRONTIERS IN PHYSIOLOGY, ISSN 1664-042X, 2013, Volume 4, p. 233
Journal Article
Journal Article
Journal Article
Journal Article
The Journal of Membrane Biology, ISSN 0022-2631, 2/2012, Volume 245, Issue 2, pp. 77 - 87
Journal Article