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by Voight, Benjamin F, PhD and Peloso, Gina M, PhD and Orho-Melander, Marju, PhD and Frikke-Schmidt, Ruth, DMSc and Barbalic, Maja, PhD and Jensen, Majken K, PhD and Hindy, George, MD and Hólm, Hilma, MD and Ding, Eric L, ScD and Johnson, Toby, PhD and Schunkert, Heribert, Prof and Samani, Nilesh J, Prof and Clarke, Robert, MD and Hopewell, Jemma C, PhD and Thompson, John F, Prof and Li, Mingyao, PhD and Thorleifsson, Gudmar, PhD and Newton-Cheh, Christopher, MD and Musunuru, Kiran, MD and Pirruccello, James P, BS and Saleheen, Danish, MBBS and Chen, Li, MSc and Stewart, Alexandre FR, PhD and Schillert, Arne, PhD and Thorsteinsdottir, Unnur, PhD and Thorgeirsson, Gudmundur, MD and Anand, Sonia, Prof and Engert, James C, PhD and Morgan, Thomas, MD and Spertus, John, Prof and Stoll, Monika, Prof and Berger, Klaus, Prof and Martinelli, Nicola, MD and Girelli, Domenico, Prof and McKeown, Pascal P, Prof and Patterson, Christopher C, PhD and Epstein, Stephen E, MD and Devaney, Joseph, PhD and Burnett, Mary-Susan, PhD and Mooser, Vincent, MD and Ripatti, Samuli, PhD and Surakka, Ida, BSci and Nieminen, Markku S, Prof and Sinisalo, Juha, MD and Lokki, Marja-Liisa, PhD and Perola, Markus, Prof and Havulinna, Aki, PhD and de Faire, Ulf, Prof and Gigante, Bruna, MD and Ingelsson, Erik, PhD and Zeller, Tanja, PhD and Wild, Philipp, MD and de Bakker, Paul I W, Prof and Klungel, Olaf H, PhD and Maitland-van der Zee, Anke-Hilse, PhD and Peters, Bas J M, PhD and de Boer, Anthonius, Prof and Grobbee, Diederick E, Prof and Kamphuisen, Pieter W, PhD and Deneer, Vera H M, PhD and Elbers, Clara C, PhD and Onland-Moret, N Charlotte, PhD and Hofker, Marten H, Prof and Wijmenga, Cisca, Prof and Verschuren, WM Monique, PhD and Boer, Jolanda MA, PhD and van der Schouw, Yvonne T, Prof and Rasheed, Asif and Frossard, Philippe and Demissie, Serkalem, PhD and Willer, Cristen, PhD and Do, Ron, PhD and Ordovas, Jose M, Prof and Abecasis, Gonçalo R, Prof and Boehnke, Michael, Prof and Mohlke, Karen L, PhD and Daly, Mark J, PhD and Guiducci, Candace, BS and Burtt, Noël P, BS and Surti, Aarti, BS and Gonzalez, Elena, BS and Purcell, Shaun, PhD and Gabriel, Stacey, PhD and Marrugat, Jaume, PhD and Peden, John, PhD and Erdmann, Jeanette, PhD and Diemert, Patrick, MD and Willenborg, Christina, MSc and König, Inke R, PhD and Fischer, Marcus, MD and Hengstenberg, Christian, MD and Ziegler, Andreas, PhD and Buysschaert, Ian, MD and Lambrechts, Diether, PhD and Van de Werf, Frans, Prof and Fox, Keith A, Prof and El Mokhtari, Nour Eddine, MD and Rubin, Diana, MD and Schrezenmeir, Jürgen, PhD and Schreiber, Stefan, Prof and ...
Lancet, The, ISSN 0140-6736, 08/2012, Volume 380, Issue 9841, pp. 572 - 580
Journal Article
by Holmes, Michael V and Dale, Caroline E and Zuccolo, Luisa and Silverwood, Richard J and Guo, Yiran and Ye, Zheng and Prieto-Merino, David and Dehghan, Abbas and Trompet, Stella and Wong, Andrew and Cavadino, Alana and Drogan, Dagmar and Padmanabhan, Sandosh and Li, Shanshan and Yesupriya, Ajay and Leusink, Maarten and Sundstrom, Johan and Hubacek, Jaroslav A and Pikhart, Hynek and Swerdlow, Daniel I and Panayiotou, Andrie G and Borinskaya, Svetlana A and Finan, Chris and Shah, Sonia and Kuchenbaecker, Karoline B and Shah, Tina and Engmann, Jorgen and Folkersen, Lasse and Eriksson, Per and Ricceri, Fulvio and Melander, Olle and Sacerdote, Carlotta and Gamble, Dale M and Rayaprolu, Sruti and Ross, Owen A and McLachlan, Stela and Vikhireva, Olga and Sluijs, Ivonne and Scott, Robert A and Adamkova, Vera and Flicker, Leon and Bockxmeer, Frank M van and Power, Christine and Marques-Vidal, Pedro and Meade, Tom and Marmot, Michael G and Ferro, Jose M and Paulos-Pinheiro, Sofia and Humphries, Steve E and Talmud, Philippa J and Leach, Irene Mateo and Verweij, Niek and Linneberg, Allan and Skaaby, Tea and Doevendans, Pieter A and Cramer, Maarten J and Harst, Pim van der and Klungel, Olaf H and Dowling, Nicole F and Dominiczak, Anna F and Kumari, Meena and Nicolaides, Andrew N and Weikert, Cornelia and Boeing, Heiner and Ebrahim, Shah and Gaunt, Tom R and Price, Jackie F and Lannfelt, Lars and Peasey, Anne and Kubinova, Ruzena and Pajak, Andrzej and Malyutina, Sofia and Voevoda, Mikhail I and Tamosiunas, Abdonas and Maitland-van der Zee, Anke H and Norman, Paul E and Hankey, Graeme J and Bergmann, Manuela M and Hofman, Albert and Franco, Oscar H and Cooper, Jackie and Palmen, Jutta and Spiering, Wilko and Jong, Pim A de and Kuh, Diana and Hardy, Rebecca and Uitterlinden, Andre G and Ikram, M Arfan and Ford, Ian and Hyppönen, Elina and Almeida, Osvaldo P and Wareham, Nicholas J and Khaw, Kay-Tee and Hamsten, Anders and Husemoen, Lise Lotte N and Tjønneland, Anne and Tolstrup, Janne S and Rimm, Eric and Beulens, Joline W J and Verschuren, W M Monique and ... and InterAct Consortium and IMPROVE Study Grp and on behalf of The InterAct Consortium and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Kardiologi and Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm and Geriatrik and Uppsala universitet and Institutionen för medicinska vetenskaper and Institutionen för folkhälso- och vårdvetenskap and Uppsala kliniska forskningscentrum (UCR)
BMJ : British Medical Journal, ISSN 0959-8138, 7/2014, Volume 349, Issue jul10 6, pp. g4164 - g4164
Journal Article
Hepatology, ISSN 0270-9139, 2015, Volume 62, Issue 6, pp. 1710 - 1722
The role of Kupffer cells (KCs) in the pathophysiology of the liver has been firmly established. Nevertheless, KCs have been underexplored as a target for... 
INCREASES HDL | CETP TRANSGENIC MICE | MESSENGER-RNA | FATTY LIVER-DISEASE | GENE-EXPRESSION | HOST-DEFENSE | WEIGHT-LOSS | NONALCOHOLIC STEATOHEPATITIS | GASTROENTEROLOGY & HEPATOLOGY | HIGH-DENSITY-LIPOPROTEIN | ADIPOSE-TISSUE | Animals | Humans | Middle Aged | Adult | Female | Male | Mice, Transgenic | Aged | Kupffer Cells - metabolism | Mice | Cholesterol Ester Transfer Proteins - metabolism
Journal Article
Journal Article
Plos One, ISSN 1932-6203, 2013, Volume 8, Issue 12, p. e78792
BACKGROUND & AIMS: While non-alcoholic steatohepatitis (NASH) is characterized by hepatic steatosis combined with inflammation, the mechanisms triggering... 
ACTIVATION | DIET | MULTIDISCIPLINARY SCIENCES | ATHEROSCLEROSIS | CRYSTALS | STEATOHEPATITIS | GUT MICROBIOTA | AUTOPHAGY | NASH | NLRP3 INFLAMMASOMES | NALP3 INFLAMMASOME | Kupffer Cells - pathology | Hyperlipidemias - genetics | Hepatitis - enzymology | Inflammasomes - metabolism | Caspase 1 - metabolism | Interleukin-1beta - genetics | Hyperlipidemias - enzymology | Lipoproteins, LDL - genetics | Cholesterol - genetics | Caspases - metabolism | Dietary Fats - pharmacology | Interleukin-1beta - metabolism | Hepatitis - genetics | Lipoproteins, LDL - metabolism | Dietary Fats - adverse effects | Caspases - genetics | Hepatitis - pathology | Cholesterol - metabolism | Inflammasomes - genetics | Kupffer Cells - enzymology | Mice, Knockout | Animals | Caspase 1 - genetics | Hyperlipidemias - pathology | Mice | Interleukin-18 - genetics | Interleukin-18 - metabolism | Research | Gene expression | Health aspects | Cholesterol | Disease | Syngeneic grafts | Caspase-11 | Liver | Kupffer cells | Bone marrow transplantation | Lipids | Activation | Macrophages | Autophagy | Caspase-1 | Toxicology | Fatty liver | Rodents | Hydrofluorocarbons | Interleukin 1 | Bone marrow | Lipoprotein (low density) receptors | Efflux | Departments | Cytokines | Incubation | Internal medicine | Crystallization | Crystals | Caspase | Inflammation | Histology | Metabolism | Steatosis | Interleukin 18 | Medicine | Nutrition research | Hypotheses | Microscopy | Bone | Phagocytosis | nonalcoholic steatohepatitis | atherosclerosis | crystals | nlrp3 inflammasomes | autophagy | disease | il-1-beta production | activation | nalp3 inflammasome | gut microbiota
Journal Article
Plos one, ISSN 1932-6203, 10/2016, Volume 11, Issue 10, pp. e0165385 - e0165385
Journal Article
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